Immunonutrition.

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Published in BMJ on July 19, 2003

Authors

Philip C Calder

Articles by these authors

(truncated to the top 100)

Association of n-3 polyunsaturated fatty acids with stability of atherosclerotic plaques: a randomised controlled trial. Lancet (2003) 2.68

Eicosapentaenoic acid (EPA) from highly concentrated n-3 fatty acid ethyl esters is incorporated into advanced atherosclerotic plaques and higher plaque EPA is associated with decreased plaque inflammation and increased stability. Atherosclerosis (2010) 2.65

Cardiovascular effects of marine omega-3 fatty acids. Lancet (2010) 2.45

Conversion of alpha-linolenic acid to longer-chain polyunsaturated fatty acids in human adults. Reprod Nutr Dev (2005) 2.28

Perioperative immunonutrition in patients undergoing liver transplantation: a randomized double-blind trial. Hepatology (2015) 2.00

Dose-related effects of eicosapentaenoic acid on innate immune function in healthy humans: a comparison of young and older men. Am J Clin Nutr (2006) 1.97

Non-alcoholic fatty liver disease: a new and important cardiovascular risk factor? Eur Heart J (2012) 1.73

Differential anti-inflammatory effects of phenolic compounds from extra virgin olive oil identified in human whole blood cultures. Nutrition (2005) 1.72

Monitoring immune modulation by nutrition in the general population: identifying and substantiating effects on human health. Br J Nutr (2013) 1.64

Prebiotics, immune function, infection and inflammation: a review of the evidence. Br J Nutr (2008) 1.63

Incorporation of eicosapentaenoic and docosahexaenoic acids into lipid pools when given as supplements providing doses equivalent to typical intakes of oily fish. Am J Clin Nutr (2012) 1.57

Differential effects of short-chain fatty acids on proliferation and production of pro- and anti-inflammatory cytokines by cultured lymphocytes. Life Sci (2003) 1.53

Evaluation of health care services provided for older adults in primary health care centers and its internal environment. A step towards age-friendly health centers. Saudi Med J (2015) 1.52

Influence of marine n-3 polyunsaturated fatty acids on immune function and a systematic review of their effects on clinical outcomes in rheumatoid arthritis. Br J Nutr (2012) 1.50

Differential immunomodulation with long-chain n-3 PUFA in health and chronic disease. Proc Nutr Soc (2007) 1.47

Effects of a fish oil containing lipid emulsion on plasma phospholipid fatty acids, inflammatory markers, and clinical outcomes in septic patients: a randomized, controlled clinical trial. Crit Care (2010) 1.47

Effects of fat and fatty acid intake on inflammatory and immune responses: a critical review. Ann Nutr Metab (2009) 1.47

PASSCLAIM--gut health and immunity. Eur J Nutr (2004) 1.43

Markers to measure immunomodulation in human nutrition intervention studies. Br J Nutr (2005) 1.42

BJN gets a new sister! Br J Nutr (2012) 1.39

The scope of the British Journal of Nutrition. Br J Nutr (2012) 1.37

Differences in matrix metalloproteinase-1 and matrix metalloproteinase-12 transcript levels among carotid atherosclerotic plaques with different histopathological characteristics. Stroke (2004) 1.35

Immune modulation by parenteral lipid emulsions. Am J Clin Nutr (2007) 1.33

Plasma cytokine response during the postprandial period: a potential causal process in vascular disease? Br J Nutr (2005) 1.30

Dietary alpha-linolenic acid and health-related outcomes: a metabolic perspective. Nutr Res Rev (2006) 1.27

Relation between the fatty acid composition of peripheral blood mononuclear cells and measures of immune cell function in healthy, free-living subjects aged 25-72 y. Am J Clin Nutr (2003) 1.26

Omega-3 fatty acid supplementation does not reduce risk of atrial fibrillation after coronary artery bypass surgery: a randomized, double-blind, placebo-controlled clinical trial. Circ Arrhythm Electrophysiol (2009) 1.26

Gender differences in the n-3 fatty acid content of tissues. Proc Nutr Soc (2008) 1.23

Omega-3 Fatty acids and inflammation: novel interactions reveal a new step in neutrophil recruitment. PLoS Biol (2009) 1.22

Polyunsaturated fatty acid concentrations in young men and women consuming their habitual diets. Br J Nutr (2006) 1.21

Lack of effect of foods enriched with plant- or marine-derived n-3 fatty acids on human immune function. Am J Clin Nutr (2003) 1.19

Inhibition of tumour necrosis factor-alpha and interleukin 6 production by mononuclear cells following dietary fish-oil supplementation in healthy men and response to antioxidant co-supplementation. Br J Nutr (2003) 1.17

Opposing effects of cis-9,trans-11 and trans-10,cis-12 conjugated linoleic acid on blood lipids in healthy humans. Am J Clin Nutr (2004) 1.16

Atopy risk in infants and children in relation to early exposure to fish, oily fish, or long-chain omega-3 fatty acids: a systematic review. Clin Rev Allergy Immunol (2011) 1.15

Effect of sex and genotype on cardiovascular biomarker response to fish oils: the FINGEN Study. Am J Clin Nutr (2008) 1.13

n-3 polyunsaturated fatty acids and colon cancer prevention. Clin Nutr (2004) 1.11

Effects of purified eicosapentaenoic and docosahexaenoic acids in nonalcoholic fatty liver disease: results from the Welcome* study. Hepatology (2014) 1.11

The ability of fish oil to suppress tumor necrosis factor alpha production by peripheral blood mononuclear cells in healthy men is associated with polymorphisms in genes that influence tumor necrosis factor alpha production. Am J Clin Nutr (2002) 1.10

Olive oil in parenteral nutrition. Curr Opin Clin Nutr Metab Care (2007) 1.10

Plant- and marine-derived n-3 polyunsaturated fatty acids have differential effects on fasting and postprandial blood lipid concentrations and on the susceptibility of LDL to oxidative modification in moderately hyperlipidemic subjects. Am J Clin Nutr (2003) 1.07

Whole-blood culture is a valid low-cost method to measure monocytic cytokines - a comparison of cytokine production in cultures of human whole-blood, mononuclear cells and monocytes. J Immunol Methods (2008) 1.06

Umbilical cord and maternal blood red cell fatty acids and early childhood wheezing and eczema. J Allergy Clin Immunol (2004) 1.05

Maternal fat intake in rats alters 20:4n-6 and 22:6n-3 status and the epigenetic regulation of Fads2 in offspring liver. J Nutr Biochem (2012) 1.03

Mechanisms involved in the cytotoxic and cytoprotective actions of saturated versus monounsaturated long-chain fatty acids in pancreatic beta-cells. J Endocrinol (2007) 1.01

Prostaglandin E2 production and T cell function after fish-oil supplementation: response to antioxidant cosupplementation. Am J Clin Nutr (2003) 1.01

Evaluation of the immune benefits of two probiotic strains Bifidobacterium animalis ssp. lactis, BB-12® and Lactobacillus paracasei ssp. paracasei, L. casei 431® in an influenza vaccination model: a randomised, double-blind, placebo-controlled study. Br J Nutr (2011) 1.00

Vascular dysfunction induced in offspring by maternal dietary fat involves altered arterial polyunsaturated fatty acid biosynthesis. PLoS One (2012) 1.00

Age-related increases in circulating inflammatory markers in men are independent of BMI, blood pressure and blood lipid concentrations. Atherosclerosis (2006) 1.00

Effects of cis-9,trans-11 and trans-10,cis-12 conjugated linoleic acid on immune cell function in healthy humans. Am J Clin Nutr (2004) 0.97

The impact of common gene variants on the response of biomarkers of cardiovascular disease (CVD) risk to increased fish oil fatty acids intakes. Annu Rev Nutr (2011) 0.97

UK Food Standards Agency Workshop Report: the effects of the dietary n-6:n-3 fatty acid ratio on cardiovascular health. Br J Nutr (2007) 0.95

Fatty acids and immune function: new insights into mechanisms. Br J Nutr (2007) 0.95

The Salmon in Pregnancy Study: study design, subject characteristics, maternal fish and marine n-3 fatty acid intake, and marine n-3 fatty acid status in maternal and umbilical cord blood. Am J Clin Nutr (2011) 0.95

Nutrition issues in Codex: health claims, nutrient reference values and WTO agreements: a conference report. Eur J Nutr (2012) 0.94

Effects of dairy products naturally enriched with cis-9,trans-11 conjugated linoleic acid on the blood lipid profile in healthy middle-aged men. Am J Clin Nutr (2006) 0.94

Gene polymorphisms, inflammatory diseases and cancer. Proc Nutr Soc (2002) 0.94

Increased intake of oily fish in pregnancy: effects on neonatal immune responses and on clinical outcomes in infants at 6 mo. Am J Clin Nutr (2012) 0.93

The influence of different combinations of gamma-linolenic acid, stearidonic acid and EPA on immune function in healthy young male subjects. Br J Nutr (2004) 0.91

Lack of effect of meal fatty acid composition on postprandial lipid, glucose and insulin responses in men and women aged 50-65 years consuming their habitual diets. Br J Nutr (2006) 0.91

Fish oil n-3 polyunsaturated fatty acids selectively affect plasma cytokines and decrease illness in Thai schoolchildren: a randomized, double-blind, placebo-controlled intervention trial. J Pediatr (2008) 0.91

Decreased tumor growth in Walker 256 tumor-bearing rats chronically supplemented with fish oil involves COX-2 and PGE2 reduction associated with apoptosis and increased peroxidation. Prostaglandins Leukot Essent Fatty Acids (2007) 0.91

The influence of different combinations of gamma-linolenic, stearidonic and eicosapentaenoic acids on the fatty acid composition of blood lipids and mononuclear cells in human volunteers. Prostaglandins Leukot Essent Fatty Acids (2004) 0.90

The polyunsaturated fatty acid composition of hepatic and plasma lipids differ by both sex and dietary fat intake in rats. J Nutr (2009) 0.90

Age- and dose-dependent effects of an eicosapentaenoic acid-rich oil on cardiovascular risk factors in healthy male subjects. Atherosclerosis (2006) 0.90

Managing adult patients who need home parenteral nutrition. BMJ (2011) 0.90

The effects of conjugated linoleic acid on human health-related outcomes. Proc Nutr Soc (2005) 0.89

Compared with daily, weekly n-3 PUFA intake affects the incorporation of eicosapentaenoic acid and docosahexaenoic acid into platelets and mononuclear cells in humans. J Nutr (2014) 0.89

Polymorphisms in the CD36 gene modulate the ability of fish oil supplements to lower fasting plasma triacyl glycerol and raise HDL cholesterol concentrations in healthy middle-aged men. Prostaglandins Leukot Essent Fatty Acids (2008) 0.89

Supplementation with a fish oil-enriched, high-protein medical food leads to rapid incorporation of EPA into white blood cells and modulates immune responses within one week in healthy men and women. J Nutr (2011) 0.88

Incorporation of cis-9,trans-11 or trans-10,cis-12 conjugated linoleic acid into plasma and cellular lipids in healthy men. J Lipid Res (2004) 0.88

Comparison of the effects of linseed oil and different doses of fish oil on mononuclear cell function in healthy human subjects. Br J Nutr (2003) 0.88

Apolipoprotein E genotype and the cardiovascular disease risk phenotype: impact of sex and adiposity (the FINGEN study). Atherosclerosis (2012) 0.87

N-3 polyunsaturated fatty acids and allergic disease. Curr Opin Clin Nutr Metab Care (2004) 0.87

CD36 and SR-BI are involved in cellular uptake of provitamin A carotenoids by Caco-2 and HEK cells, and some of their genetic variants are associated with plasma concentrations of these micronutrients in humans. J Nutr (2013) 0.87

Peripheral blood mononuclear cell fatty acid composition and inflammatory mediator production in adult Crohn's disease. Clin Nutr (2004) 0.86

High-dose fish oil and antioxidants in Crohn's disease and the response of bone turnover: a randomised controlled trial. Br J Nutr (2005) 0.86

Effect of reduced maternal protein intake in pregnancy in the rat on the fatty acid composition of brain, liver, plasma, heart and lung phospholipids of the offspring after weaning. Br J Nutr (2003) 0.86

Influence of yeast-derived 1,3/1,6 glucopolysaccharide on circulating cytokines and chemokines with respect to upper respiratory tract infections. Nutrition (2012) 0.85

Perioperative immunonutrition in well-nourished patients undergoing surgery for head and neck cancer: evaluation of inflammatory and immunologic outcomes. Nutrients (2013) 0.84

Short-term infusion of a fish oil-based lipid emulsion modulates fatty acid status, but not immune function or (anti)oxidant balance: a randomized cross-over study. Eur J Clin Invest (2011) 0.84

Fish oil supplementation improves neutrophil function during cancer chemotherapy. Lipids (2011) 0.84

Variants in the genes encoding TNF-α, IL-10, and GSTP1 influence the effect of α-tocopherol on inflammatory cell responses in healthy men. Am J Clin Nutr (2012) 0.83

Docosahexaenoic acid inhibits the adhesion of flowing neutrophils to cytokine stimulated human umbilical vein endothelial cells. J Nutr (2011) 0.83

Altered colonic mucosal Polyunsaturated Fatty Acid (PUFA) derived lipid mediators in ulcerative colitis: new insight into relationship with disease activity and pathophysiology. PLoS One (2013) 0.83

The effect of feeding structured triacylglycerols enriched in eicosapentaenoic or docosahexaenoic acids on murine splenocyte fatty acid composition and leucocyte phagocytosis. Br J Nutr (2003) 0.83

Stearidonic acid as a supplemental source of ω-3 polyunsaturated fatty acids to enhance status for improved human health. Nutrition (2012) 0.83

Dietary free oleic and linoleic acid enhances neutrophil function and modulates the inflammatory response in rats. Lipids (2010) 0.82

Plant and marine derived (n-3) polyunsaturated fatty acids do not affect blood coagulation and fibrinolytic factors in moderately hyperlipidemic humans. J Nutr (2003) 0.82

The effect of dietary supplementation with linoleic acid to late gestation ewes on the fatty acid composition of maternal and fetal plasma and tissues and the synthetic capacity of the placenta for 2-series prostaglandins. Biochim Biophys Acta (2004) 0.82

Salmon consumption during pregnancy alters fatty acid composition and secretory IgA concentration in human breast milk. J Nutr (2012) 0.82

Old study sheds new light on the fatty acids and cardiovascular health debate. BMJ (2013) 0.82

Fish oil and antioxidants alter the composition and function of circulating mononuclear cells in Crohn disease. Am J Clin Nutr (2004) 0.82

Different intakes of n-3 fatty acids among pregnant women in 3 regions of China with contrasting dietary patterns are reflected in maternal but not in umbilical erythrocyte phosphatidylcholine fatty acid composition. Nutr Res (2013) 0.82

Acute appearance of fatty acids in human plasma--a comparative study between polar-lipid rich oil from the microalgae Nannochloropsis oculata and krill oil in healthy young males. Lipids Health Dis (2013) 0.82

Effect of oxygen tension on the amino acid utilisation of human embryonic stem cells. Cell Physiol Biochem (2014) 0.82

UK Food Standards Agency alpha-linolenic acid workshop report. Br J Nutr (2002) 0.82

Is there a case for n-3 fatty acid supplementation in cystic fibrosis? Curr Opin Clin Nutr Metab Care (2005) 0.82

Fatty acids, lipid emulsions and the immune and inflammatory systems. World Rev Nutr Diet (2014) 0.82

Lower omega-3 fatty acid intake and status are associated with poorer cognitive function in older age: A comparison of individuals with and without cognitive impairment and Alzheimer's disease. Nutr Neurosci (2012) 0.81

β2-1 Fructans have a bifidogenic effect in healthy middle-aged human subjects but do not alter immune responses examined in the absence of an in vivo immune challenge: results from a randomised controlled trial. Br J Nutr (2012) 0.81