Published in Diabetes on August 01, 2003
Vascular and inflammatory stresses mediate atherosclerosis via RAGE and its ligands in apoE-/- mice. J Clin Invest (2008) 3.11
The RAGE axis: a fundamental mechanism signaling danger to the vulnerable vasculature. Circ Res (2010) 2.19
AGE restriction in diabetes mellitus: a paradigm shift. Nat Rev Endocrinol (2011) 1.46
A perspective on the Maillard reaction and the analysis of protein glycation by mass spectrometry: probing the pathogenesis of chronic disease. J Proteome Res (2009) 1.31
RAGE mediates podocyte injury in adriamycin-induced glomerulosclerosis. J Am Soc Nephrol (2008) 1.24
Modifying apolipoprotein A-I by malondialdehyde, but not by an array of other reactive carbonyls, blocks cholesterol efflux by the ABCA1 pathway. J Biol Chem (2010) 1.19
Radical roles for RAGE in the pathogenesis of oxidative stress in cardiovascular diseases and beyond. Int J Mol Sci (2013) 1.15
Differential roles of NADPH oxidases in vascular physiology and pathophysiology. Front Biosci (Schol Ed) (2012) 0.95
NADPH Oxidase versus Mitochondria-Derived ROS in Glucose-Induced Apoptosis of Pericytes in Early Diabetic Retinopathy. J Ophthalmol (2010) 0.95
Advanced glycation end products on stored red blood cells increase endothelial reactive oxygen species generation through interaction with receptor for advanced glycation end products. Transfusion (2010) 0.92
Renal endothelial dysfunction in diabetic nephropathy. Cardiovasc Hematol Disord Drug Targets (2014) 0.90
Anti-inflammatory agents and monoHER protect against DOX-induced cardiotoxicity and accumulation of CML in mice. Br J Cancer (2007) 0.85
Reactive carbonyl compounds (RCCs) cause aggregation and dysfunction of fibrinogen. Protein Cell (2012) 0.80
Hypochlorous acid converts the gamma-glutamyl group of glutathione disulfide to 5-hydroxybutyrolactam, a potential marker for neutrophil activation. J Biol Chem (2009) 0.80
Serum carboxymethyl-lysine, disability, and frailty in older persons: the Cardiovascular Health Study. J Gerontol A Biol Sci Med Sci (2013) 0.79
Effect of chronic hypoxia on RAGE and its soluble forms in lungs and plasma of mice. Biochim Biophys Acta (2015) 0.78
Advanced glycation end products in diabetic cardiomyopathy: an alternative hypothesis. J Heart Lung Transplant (2011) 0.76
Non-professional marathon running: RAGE axis and ST2 family changes in relation to open-window effect, inflammation and renal function. Sci Rep (2016) 0.75
Effect of dietary prebiotic supplementation on advanced glycation, insulin resistance and inflammatory biomarkers in adults with pre-diabetes: a study protocol for a double-blind placebo-controlled randomised crossover clinical trial. BMC Endocr Disord (2014) 0.75
Shotgun proteomics implicates protease inhibition and complement activation in the antiinflammatory properties of HDL. J Clin Invest (2007) 5.38
Quantification of thyroglobulin, a low-abundance serum protein, by immunoaffinity peptide enrichment and tandem mass spectrometry. Clin Chem (2008) 3.23
Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet. Am J Physiol Endocrinol Metab (2008) 2.86
ATP-binding cassette transporter A1: a cell cholesterol exporter that protects against cardiovascular disease. Physiol Rev (2005) 2.76
Bioluminescence imaging of myeloperoxidase activity in vivo. Nat Med (2009) 2.43
The myeloperoxidase product hypochlorous acid oxidizes HDL in the human artery wall and impairs ABCA1-dependent cholesterol transport. Proc Natl Acad Sci U S A (2004) 2.39
Myeloperoxidase impairs ABCA1-dependent cholesterol efflux through methionine oxidation and site-specific tyrosine chlorination of apolipoprotein A-I. J Biol Chem (2006) 1.95
Diabetes promotes an inflammatory macrophage phenotype and atherosclerosis through acyl-CoA synthetase 1. Proc Natl Acad Sci U S A (2012) 1.91
High-density lipoprotein suppresses the type I interferon response, a family of potent antiviral immunoregulators, in macrophages challenged with lipopolysaccharide. Circulation (2010) 1.80
Bcl-xL deamidation is a critical switch in the regulation of the response to DNA damage. Cell (2002) 1.76
Monocyte chemoattractant protein deficiency fails to restrain macrophage infiltration into adipose tissue [corrected]. Diabetes (2008) 1.72
Tyrosine 192 in apolipoprotein A-I is the major site of nitration and chlorination by myeloperoxidase, but only chlorination markedly impairs ABCA1-dependent cholesterol transport. J Biol Chem (2004) 1.71
Human atherosclerotic intima and blood of patients with established coronary artery disease contain high density lipoprotein damaged by reactive nitrogen species. J Biol Chem (2004) 1.68
Methionine oxidation impairs reverse cholesterol transport by apolipoprotein A-I. Proc Natl Acad Sci U S A (2008) 1.63
Thematic review series: The immune system and atherogenesis. Lipoprotein-associated inflammatory proteins: markers or mediators of cardiovascular disease? J Lipid Res (2005) 1.61
Spectral index for assessment of differential protein expression in shotgun proteomics. J Proteome Res (2008) 1.55
High-density lipoproteins: a consensus statement from the National Lipid Association. J Clin Lipidol (2013) 1.50
Myeloperoxidase-generated oxidants modulate left ventricular remodeling but not infarct size after myocardial infarction. Circulation (2005) 1.42
Ablation of the inflammatory enzyme myeloperoxidase mitigates features of Parkinson's disease in mice. J Neurosci (2005) 1.40
Oxidative stress and endothelial dysfunction in vascular disease. Curr Diab Rep (2007) 1.39
Combined statin and niacin therapy remodels the high-density lipoprotein proteome. Circulation (2008) 1.38
Mechanisms for oxidative stress in diabetic cardiovascular disease. Antioxid Redox Signal (2007) 1.37
Myeloperoxidase produces nitrating oxidants in vivo. J Clin Invest (2002) 1.35
Expression of human myeloperoxidase by macrophages promotes atherosclerosis in mice. Circulation (2005) 1.32
Myeloperoxidase: an inflammatory enzyme for generating dysfunctional high density lipoprotein. Curr Opin Cardiol (2006) 1.30
Type 1 diabetes promotes disruption of advanced atherosclerotic lesions in LDL receptor-deficient mice. Proc Natl Acad Sci U S A (2008) 1.28
Myeloperoxidase targets apolipoprotein A-I, the major high density lipoprotein protein, for site-specific oxidation in human atherosclerotic lesions. J Biol Chem (2012) 1.28
Neuronal expression of myeloperoxidase is increased in Alzheimer's disease. J Neurochem (2004) 1.27
Lysine residues direct the chlorination of tyrosines in YXXK motifs of apolipoprotein A-I when hypochlorous acid oxidizes high density lipoprotein. J Biol Chem (2003) 1.27
Acrolein impairs ATP binding cassette transporter A1-dependent cholesterol export from cells through site-specific modification of apolipoprotein A-I. J Biol Chem (2005) 1.27
Myeloperoxidase: an oxidative pathway for generating dysfunctional high-density lipoprotein. Chem Res Toxicol (2010) 1.25
The interplay between size, morphology, stability, and functionality of high-density lipoprotein subclasses. Biochemistry (2008) 1.24
Unique proteomic signatures distinguish macrophages and dendritic cells. PLoS One (2012) 1.24
A macrophage sterol-responsive network linked to atherogenesis. Cell Metab (2010) 1.23
Translation of high-density lipoprotein function into clinical practice: current prospects and future challenges. Circulation (2013) 1.23
Serum amyloid A3 does not contribute to circulating SAA levels. J Lipid Res (2009) 1.23
HDL, lipid peroxidation, and atherosclerosis. J Lipid Res (2009) 1.22
Human neutrophils use the myeloperoxidase-hydrogen peroxide-chloride system to chlorinate but not nitrate bacterial proteins during phagocytosis. J Biol Chem (2002) 1.22
Advanced glycation end product precursors impair ABCA1-dependent cholesterol removal from cells. Diabetes (2005) 1.22
S100A9 differentially modifies phenotypic states of neutrophils, macrophages, and dendritic cells: implications for atherosclerosis and adipose tissue inflammation. Circulation (2011) 1.20
Generation of intramolecular and intermolecular sulfenamides, sulfinamides, and sulfonamides by hypochlorous acid: a potential pathway for oxidative cross-linking of low-density lipoprotein by myeloperoxidase. Biochemistry (2002) 1.20
Methionine oxidation contributes to bacterial killing by the myeloperoxidase system of neutrophils. Proc Natl Acad Sci U S A (2009) 1.20
Modifying apolipoprotein A-I by malondialdehyde, but not by an array of other reactive carbonyls, blocks cholesterol efflux by the ABCA1 pathway. J Biol Chem (2010) 1.19
Proteomic and computational analysis of bronchoalveolar proteins during the course of the acute respiratory distress syndrome. Am J Respir Crit Care Med (2008) 1.17
Hyperlipidemia in concert with hyperglycemia stimulates the proliferation of macrophages in atherosclerotic lesions: potential role of glucose-oxidized LDL. Diabetes (2004) 1.14
Lipoproteomics: using mass spectrometry-based proteomics to explore the assembly, structure, and function of lipoproteins. J Lipid Res (2009) 1.11
Reactive carbonyls and polyunsaturated fatty acids produce a hydroxyl radical-like species: a potential pathway for oxidative damage of retinal proteins in diabetes. J Biol Chem (2005) 1.10
Oxidation of apolipoprotein A-I by myeloperoxidase impairs the initial interactions with ABCA1 required for signaling and cholesterol export. J Lipid Res (2010) 1.09
Myeloperoxidase plays critical roles in killing Klebsiella pneumoniae and inactivating neutrophil elastase: effects on host defense. J Immunol (2005) 1.09
Phagocytes produce 5-chlorouracil and 5-bromouracil, two mutagenic products of myeloperoxidase, in human inflammatory tissue. J Biol Chem (2003) 1.08
MMP-9 sheds the beta2 integrin subunit (CD18) from macrophages. Mol Cell Proteomics (2008) 1.08
Serum amyloid A facilitates the binding of high-density lipoprotein from mice injected with lipopolysaccharide to vascular proteoglycans. Arterioscler Thromb Vasc Biol (2011) 1.08
Myeloperoxidase inactivates TIMP-1 by oxidizing its N-terminal cysteine residue: an oxidative mechanism for regulating proteolysis during inflammation. J Biol Chem (2007) 1.06
Using tandem mass spectrometry to quantify site-specific chlorination and nitration of proteins: model system studies with high-density lipoprotein oxidized by myeloperoxidase. Methods Enzymol (2008) 1.05
NADPH oxidase restrains the matrix metalloproteinase activity of macrophages. J Biol Chem (2005) 1.04
TLR-2/TLR-4 TREM-1 signaling pathway is dispensable in inflammatory myeloid cells during sterile kidney injury. PLoS One (2013) 1.03
Apolipoprotein M binds oxidized phospholipids and increases the antioxidant effect of HDL. Atherosclerosis (2011) 1.03
Retracted Activation and silencing of matrix metalloproteinases. Semin Cell Dev Biol (2007) 1.01
Resident renal mononuclear phagocytes comprise five discrete populations with distinct phenotypes and functions. J Immunol (2013) 1.01
Mapping the lung proteome in cystic fibrosis. J Proteome Res (2009) 1.01
Exchange of apolipoprotein A-I between lipid-associated and lipid-free states: a potential target for oxidative generation of dysfunctional high density lipoproteins. J Biol Chem (2010) 1.01
High density lipoprotein is targeted for oxidation by myeloperoxidase in rheumatoid arthritis. Ann Rheum Dis (2013) 1.00
Oxidative cross-linking of tryptophan to glycine restrains matrix metalloproteinase activity: specific structural motifs control protein oxidation. J Biol Chem (2003) 1.00
Misincorporation of free m-tyrosine into cellular proteins: a potential cytotoxic mechanism for oxidized amino acids. Biochem J (2006) 0.99
A fluorescent probe for the detection of myeloperoxidase activity in atherosclerosis-associated macrophages. Chem Biol (2007) 0.99
Enhanced cellular uptake of remnant high-density lipoprotein particles: a mechanism for high-density lipoprotein lowering in insulin resistance and hypertriglyceridemia. Circ Res (2008) 0.97
The biological activity of FasL in human and mouse lungs is determined by the structure of its stalk region. J Clin Invest (2011) 0.96
Phospholipid transfer protein in human plasma associates with proteins linked to immunity and inflammation. Biochemistry (2010) 0.96
Low clusterin levels in high-density lipoprotein associate with insulin resistance, obesity, and dyslipoproteinemia. Arterioscler Thromb Vasc Biol (2010) 0.96
Mechanisms of oxidative stress in diabetes: implications for the pathogenesis of vascular disease and antioxidant therapy. Front Biosci (2004) 0.94
Myeloperoxidase generates 5-chlorouracil in human atherosclerotic tissue: a potential pathway for somatic mutagenesis by macrophages. J Biol Chem (2005) 0.93
Metalloproteinase-mediated Shedding of Integrin β2 promotes macrophage efflux from inflammatory sites. J Biol Chem (2011) 0.93
Myeloperoxidase and inflammatory proteins: pathways for generating dysfunctional high-density lipoprotein in humans. Curr Atheroscler Rep (2007) 0.91
Impact of HDL oxidation by the myeloperoxidase system on sterol efflux by the ABCA1 pathway. J Proteomics (2011) 0.90
Vitamin C fails to protect amino acids and lipids from oxidation during acute inflammation. Free Radic Biol Med (2006) 0.88
Methionine sulfoxide and proteolytic cleavage contribute to the inactivation of cathepsin G by hypochlorous acid: an oxidative mechanism for regulation of serine proteinases by myeloperoxidase. J Biol Chem (2005) 0.88
Testosterone replacement in hypogonadal men alters the HDL proteome but not HDL cholesterol efflux capacity. J Lipid Res (2012) 0.87
Macrophage metalloelastase (MMP12) regulates adipose tissue expansion, insulin sensitivity, and expression of inducible nitric oxide synthase. Endocrinology (2014) 0.86
A sensitive and specific ELISA detects methionine sulfoxide-containing apolipoprotein A-I in HDL. J Lipid Res (2008) 0.86
Acrolein modifies apolipoprotein A-I in the human artery wall. Ann N Y Acad Sci (2005) 0.86
Pathways for oxidation of high-density lipoprotein in human cardiovascular disease. Curr Opin Mol Ther (2006) 0.86
An experimentally robust model of monomeric apolipoprotein A-I created from a chimera of two X-ray structures and molecular dynamics simulations. Biochemistry (2014) 0.84
Copper-mediated intra-ligand oxygen transfer in gas-phase complexes with 3-nitrotyrosine. J Mass Spectrom (2005) 0.83
Oxidized HDL: the paradox-idation of lipoproteins. Arterioscler Thromb Vasc Biol (2003) 0.82
Identification and quantification of mutagenic halogenated cytosines by gas chromatography, fast atom bombardment, and electrospray ionization tandem mass spectrometry. Anal Biochem (2003) 0.80
Cholesterol accumulation regulates expression of macrophage proteins implicated in proteolysis and complement activation. Arterioscler Thromb Vasc Biol (2012) 0.80
Acute sex steroid withdrawal increases cholesterol efflux capacity and HDL-associated clusterin in men. Steroids (2012) 0.80
Hypochlorous acid converts the gamma-glutamyl group of glutathione disulfide to 5-hydroxybutyrolactam, a potential marker for neutrophil activation. J Biol Chem (2009) 0.80
Cholesterol efflux capacity, macrophage reverse cholesterol transport and cardioprotective HDL. Curr Opin Lipidol (2015) 0.78
Impact of mifepristone, a glucocorticoid/progesterone antagonist, on HDL cholesterol, HDL particle concentration, and HDL function. J Clin Endocrinol Metab (2012) 0.77
A "new" thematic series: mass spectrometry-based proteomics of lipid biology. J Lipid Res (2009) 0.76
Conservation of apolipoprotein A-I's central domain structural elements upon lipid association on different high-density lipoprotein subclasses. Biochemistry (2013) 0.76
8-Nitroxanthine, a product of myeloperoxidase, peroxynitrite, and activated human neutrophils, enhances generation of superoxide by xanthine oxidase. Arch Biochem Biophys (2003) 0.76
HDL's protein cargo: friend or foe in cardioprotection? Circulation (2013) 0.75
Specific sequence motifs direct the oxygenation and chlorination of tryptophan by myeloperoxidase. Biochemistry (2006) 0.75
When good cholesterol turns bad: the evolving saga of CETP inhibitors and clinical strategies to elevate high-density lipoprotein. Curr Diab Rep (2008) 0.75
Time to ditch HDL-C as a measure of HDL function? Curr Opin Lipidol (2017) 0.75
Chemical knockout of C-reactive protein in cardiovascular disease. Nat Chem Biol (2006) 0.75