Published in Eur J Immunol on July 01, 2003
The canonical Wnt signaling pathway plays an important role in lymphopoiesis and hematopoiesis. Eur J Immunol (2008) 2.37
Update on Wnt signaling in bone cell biology and bone disease. Gene (2011) 2.03
Keratinocyte growth factor (KGF) is required for postnatal thymic regeneration. Blood (2005) 1.65
Global regulator SATB1 recruits beta-catenin and regulates T(H)2 differentiation in Wnt-dependent manner. PLoS Biol (2010) 1.64
Wnt signaling in the thymus is regulated by differential expression of intracellular signaling molecules. Proc Natl Acad Sci U S A (2006) 1.24
Noncanonical Wnt signaling promotes apoptosis in thymocyte development. J Exp Med (2007) 1.10
T cell factor 1 regulates thymocyte survival via a RORγt-dependent pathway. J Immunol (2011) 1.00
Thymus involution and regeneration: two sides of the same coin? Nat Rev Immunol (2013) 0.99
DKK1 mediated inhibition of Wnt signaling in postnatal mice leads to loss of TEC progenitors and thymic degeneration. PLoS One (2010) 0.99
Wnt4 and LAP2alpha as pacemakers of thymic epithelial senescence. PLoS One (2010) 0.95
Wnt-4 protects thymic epithelial cells against dexamethasone-induced senescence. Rejuvenation Res (2011) 0.87
Prenatal cadmium exposure dysregulates sonic hedgehog and Wnt/beta-catenin signaling in the thymus resulting in altered thymocyte development. Toxicol Appl Pharmacol (2009) 0.86
Gene expression profile of the third pharyngeal pouch reveals role of mesenchymal MafB in embryonic thymus development. Blood (2009) 0.81
Assessing breast cancer cell lines as tumour models by comparison of mRNA expression profiles. Breast Cancer Res (2015) 0.80
GSK3-mediated instability of tubulin polymers is responsible for the failure of immature CD4+CD8+ thymocytes to polarize their MTOC in response to TCR stimulation. Int Immunol (2011) 0.77
Developing stratified epithelia: lessons from the epidermis and thymus. Wiley Interdiscip Rev Dev Biol (2014) 0.76
Decline of FOXN1 gene expression in human thymus correlates with age: possible epigenetic regulation. Immun Ageing (2015) 0.76
Dual epithelial and immune cell function of Dvl1 regulates gut microbiota composition and intestinal homeostasis. JCI Insight (2016) 0.75
Wnt signalling meets epigenetics. Stem Cell Investig (2016) 0.75
In vivo lineage tracing reveals Axin2-expressing, long-lived cortical thymic epithelial progenitors in the postnatal thymus. PLoS One (2017) 0.75
Trans-endocytosis of CD80 and CD86: a molecular basis for the cell-extrinsic function of CTLA-4. Science (2011) 4.96
RANK signals from CD4(+)3(-) inducer cells regulate development of Aire-expressing epithelial cells in the thymic medulla. J Exp Med (2007) 2.91
Progression through key stages of haemopoiesis is dependent on distinct threshold levels of c-Myb. EMBO J (2003) 2.61
Clonal analysis reveals a common progenitor for thymic cortical and medullary epithelium. Nature (2006) 2.32
Rank signaling links the development of invariant γδ T cell progenitors and Aire(+) medullary epithelium. Immunity (2012) 1.94
Redefining epithelial progenitor potential in the developing thymus. Eur J Immunol (2007) 1.81
Generation of both cortical and Aire(+) medullary thymic epithelial compartments from CD205(+) progenitors. Eur J Immunol (2013) 1.75
Lymphotoxin-β receptor signaling through NF-κB2-RelB pathway reprograms adipocyte precursors as lymph node stromal cells. Immunity (2012) 1.75
Roquin differentiates the specialized functions of duplicated T cell costimulatory receptor genes CD28 and ICOS. Immunity (2009) 1.70
The thymic medulla is required for Foxp3+ regulatory but not conventional CD4+ thymocyte development. J Exp Med (2013) 1.70
Generating intrathymic microenvironments to establish T-cell tolerance. Nat Rev Immunol (2007) 1.68
Heterogeneity of lymphoid tissue inducer cell populations present in embryonic and adult mouse lymphoid tissues. Immunology (2008) 1.54
OX40 ligand and CD30 ligand are expressed on adult but not neonatal CD4+CD3- inducer cells: evidence that IL-7 signals regulate CD30 ligand but not OX40 ligand expression. J Immunol (2005) 1.45
Lymphoid tissue inducer cells and the evolution of CD4 dependent high-affinity antibody responses. Prog Mol Biol Transl Sci (2010) 1.45
Checkpoints in the development of thymic cortical epithelial cells. J Immunol (2009) 1.40
Function of CD4+CD3- cells in relation to B- and T-zone stroma in spleen. Blood (2006) 1.31
Neonatal and adult CD4+ CD3- cells share similar gene expression profile, and neonatal cells up-regulate OX40 ligand in response to TL1A (TNFSF15). J Immunol (2006) 1.26
Establishment and functioning of intrathymic microenvironments. Immunol Rev (2006) 1.22
Ontogeny of stromal organizer cells during lymph node development. J Immunol (2010) 1.20
Lymphotoxin signals from positively selected thymocytes regulate the terminal differentiation of medullary thymic epithelial cells. J Immunol (2010) 1.20
CD248/Endosialin is dynamically expressed on a subset of stromal cells during lymphoid tissue development, splenic remodeling and repair. FEBS Lett (2007) 1.16
PDGFRalpha-expressing mesenchyme regulates thymus growth and the availability of intrathymic niches. Blood (2006) 1.10
Differential requirement for mesenchyme in the proliferation and maturation of thymic epithelial progenitors. J Exp Med (2003) 1.10
T/B lineage choice occurs prior to intrathymic Notch signaling. Blood (2005) 1.10
An epithelial progenitor pool regulates thymus growth. J Immunol (2008) 1.10
Lymphotoxin a-dependent and -independent signals regulate stromal organizer cell homeostasis during lymph node organogenesis. Blood (2007) 1.09
Exercise capacity and progression from prehypertension to hypertension. Hypertension (2012) 1.08
Overexpression of ICAT highlights a role for catenin-mediated canonical Wnt signalling in early T cell development. Eur J Immunol (2006) 1.07
OX40 and CD30 signals in CD4(+) T-cell effector and memory function: a distinct role for lymphoid tissue inducer cells in maintaining CD4(+) T-cell memory but not effector function. Immunol Rev (2011) 1.05
A distinct subset of podoplanin (gp38) expressing F4/80+ macrophages mediate phagocytosis and are induced following zymosan peritonitis. FEBS Lett (2010) 1.04
Abrogation of CD30 and OX40 signals prevents autoimmune disease in FoxP3-deficient mice. J Exp Med (2011) 1.03
Microenvironmental regulation of Notch signalling in T cell development. Semin Immunol (2003) 1.03
The role of lymphoid tissue inducer cells in splenic white pulp development. Eur J Immunol (2007) 1.03
Lymphoid tissue inducer cells in adaptive CD4 T cell dependent responses. Semin Immunol (2008) 1.03
A stroma-derived defect in NF-kappaB2-/- mice causes impaired lymph node development and lymphocyte recruitment. J Immunol (2004) 1.03
AIRE's CARD revealed, a new structure for central tolerance provokes transcriptional plasticity. J Biol Chem (2007) 1.03
CD117⁺ CD3⁻ CD56⁻ OX40Lhigh cells express IL-22 and display an LTi phenotype in human secondary lymphoid tissues. Eur J Immunol (2011) 1.02
Cutting edge: lymphoid tissue inducer cells maintain memory CD4 T cells within secondary lymphoid tissue. J Immunol (2012) 1.02
Sequential phases in the development of Aire-expressing medullary thymic epithelial cells involve distinct cellular input. Eur J Immunol (2008) 1.02
The thymus and T-cell commitment: the right niche for Notch? Nat Rev Immunol (2006) 1.02
Serial progression of cortical and medullary thymic epithelial microenvironments. Eur J Immunol (2013) 1.01
Critical synergy of CD30 and OX40 signals in CD4 T cell homeostasis and Th1 immunity to Salmonella. J Immunol (2008) 0.99
Involvement of CCR9 at multiple stages of adult T lymphopoiesis. J Leukoc Biol (2007) 0.99
Entry into the thymic microenvironment triggers Notch activation in the earliest migrant T cell progenitors. J Immunol (2003) 0.99
Thymic function is maintained during Salmonella-induced atrophy and recovery. J Immunol (2012) 0.98
Enhanced selection of FoxP3+ T-regulatory cells protects CTLA-4-deficient mice from CNS autoimmune disease. Proc Natl Acad Sci U S A (2009) 0.96
Ly49H+ NK cells migrate to and protect splenic white pulp stroma from murine cytomegalovirus infection. J Immunol (2008) 0.96
An essential role for medullary thymic epithelial cells during the intrathymic development of invariant NKT cells. J Immunol (2014) 0.96
Wnt4 and LAP2alpha as pacemakers of thymic epithelial senescence. PLoS One (2010) 0.95
The pericyte and stromal cell marker CD248 (endosialin) is required for efficient lymph node expansion. Eur J Immunol (2010) 0.95
Mutation in the TCRα subunit constant gene (TRAC) leads to a human immunodeficiency disorder characterized by a lack of TCRαβ+ T cells. J Clin Invest (2011) 0.95
Expression of the Ian family of putative GTPases during T cell development and description of an Ian with three sets of GTP/GDP-binding motifs. Int Immunol (2005) 0.95
Developmentally regulated availability of RANKL and CD40 ligand reveals distinct mechanisms of fetal and adult cross-talk in the thymus medulla. J Immunol (2012) 0.94
Human and non-human primate intestinal FcRn expression and immunoglobulin G transcytosis. Pharm Res (2013) 0.92
EphrinB1-EphB signaling regulates thymocyte-epithelium interactions involved in functional T cell development. Eur J Immunol (2007) 0.91
Lymphoid tissue inducer cells: pivotal cells in the evolution of CD4 immunity and tolerance? Front Immunol (2012) 0.91
TSCOT+ thymic epithelial cell-mediated sensitive CD4 tolerance by direct presentation. PLoS Biol (2008) 0.91
One for all and all for one: thymic epithelial stem cells and regeneration. Trends Immunol (2002) 0.91
A roadmap for thymic epithelial cell development. Eur J Immunol (2009) 0.91
Role of CD30 in B/T segregation in the spleen. J Immunol (2007) 0.90
Chemokine receptor expression defines heterogeneity in the earliest thymic migrants. Eur J Immunol (2007) 0.89
Wnt-4 protects thymic epithelial cells against dexamethasone-induced senescence. Rejuvenation Res (2011) 0.87
Thymus medulla fosters generation of natural Treg cells, invariant γδ T cells, and invariant NKT cells: what we learn from intrathymic migration. Eur J Immunol (2015) 0.87
Mesenchymal cells regulate retinoic acid receptor-dependent cortical thymic epithelial cell homeostasis. J Immunol (2012) 0.87
Phenotypic characterization of CD3-7+ cells in developing human intestine and an analysis of their ability to differentiate into T cells. J Immunol (2005) 0.87
Clonal analysis reveals uniformity in the molecular profile and lineage potential of CCR9(+) and CCR9(-) thymus-settling progenitors. J Immunol (2011) 0.85
Lymphoid tissue inducer cells: innate cells critical for CD4+ T cell memory responses? Ann N Y Acad Sci (2012) 0.83
A novel method to allow noninvasive, longitudinal imaging of the murine immune system in vivo. Blood (2012) 0.83
Absence of thymus crosstalk in the fetus does not preclude hematopoietic induction of a functional thymus in the adult. Eur J Immunol (2009) 0.83
Cutting edge: a chemical genetic system for the analysis of kinases regulating T cell development. J Immunol (2003) 0.83
Development of functional thymic epithelial cells occurs independently of lymphostromal interactions. Mech Dev (2005) 0.83