| Rank |
Title |
Journal |
Year |
PubWeight™‹?› |
|
1
|
Presenilin clinical mutations can affect gamma-secretase activity by different mechanisms.
|
J Neurochem
|
2006
|
3.03
|
|
2
|
The mechanism of γ-Secretase dysfunction in familial Alzheimer disease.
|
EMBO J
|
2012
|
2.72
|
|
3
|
gamma-Secretase heterogeneity in the Aph1 subunit: relevance for Alzheimer's disease.
|
Science
|
2009
|
2.43
|
|
4
|
Effect of sample collection tubes on cerebrospinal fluid concentrations of tau proteins and amyloid beta peptides.
|
Clin Chem
|
2006
|
1.54
|
|
5
|
Neurochemical diagnosis of Alzheimer's dementia by CSF Abeta42, Abeta42/Abeta40 ratio and total tau.
|
Neurobiol Aging
|
2004
|
1.48
|
|
6
|
Amyloid beta peptide ratio 42/40 but not A beta 42 correlates with phospho-Tau in patients with low- and high-CSF A beta 40 load.
|
J Neurochem
|
2007
|
1.28
|
|
7
|
Cerebrospinal fluid amyloid beta peptide patterns in Alzheimer's disease patients and nondemented controls depend on sample pretreatment: indication of carrier-mediated epitope masking of amyloid beta peptides.
|
Electrophoresis
|
2004
|
1.27
|
|
8
|
International quality control survey of neurochemical dementia diagnostics.
|
Neurosci Lett
|
2006
|
1.26
|
|
9
|
Retrieval of the Alzheimer's amyloid precursor protein from the endosome to the TGN is S655 phosphorylation state-dependent and retromer-mediated.
|
Mol Neurodegener
|
2010
|
1.25
|
|
10
|
CSF amyloid-beta-peptides in Alzheimer's disease, dementia with Lewy bodies and Parkinson's disease dementia.
|
Brain
|
2006
|
1.25
|
|
11
|
Amyloid beta peptide 1-40 enhances the action of Toll-like receptor-2 and -4 agonists but antagonizes Toll-like receptor-9-induced inflammation in primary mouse microglial cell cultures.
|
J Neurochem
|
2005
|
1.14
|
|
12
|
Independent generation of Abeta42 and Abeta38 peptide species by gamma-secretase.
|
J Biol Chem
|
2008
|
1.13
|
|
13
|
Tau protein phosphorylated at threonine 181 in CSF as a neurochemical biomarker in Alzheimer's disease: original data and review of the literature.
|
J Mol Neurosci
|
2004
|
1.13
|
|
14
|
Combined CSF tau, p-tau181 and amyloid-beta 38/40/42 for diagnosing Alzheimer's disease.
|
J Neural Transm (Vienna)
|
2009
|
1.10
|
|
15
|
Multiplexed quantification of dementia biomarkers in the CSF of patients with early dementias and MCI: a multicenter study.
|
Neurobiol Aging
|
2007
|
1.10
|
|
16
|
Presenilin-1 L166P mutant human pluripotent stem cell-derived neurons exhibit partial loss of γ-secretase activity in endogenous amyloid-β generation.
|
Am J Pathol
|
2012
|
1.04
|
|
17
|
Beta-amyloid peptides in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease.
|
Ann Neurol
|
2003
|
1.02
|
|
18
|
Amyloid beta peptides in cerebrospinal fluid as profiled with surface enhanced laser desorption/ionization time-of-flight mass spectrometry: evidence of novel biomarkers in Alzheimer's disease.
|
Biol Psychiatry
|
2004
|
1.01
|
|
19
|
Heart fatty acid binding protein as a potential diagnostic marker for neurodegenerative diseases.
|
Neurosci Lett
|
2004
|
0.99
|
|
20
|
Blood-based neurochemical diagnosis of vascular dementia: a pilot study.
|
J Neurochem
|
2007
|
0.96
|
|
21
|
Urea-based two-dimensional electrophoresis of beta-amyloid peptides in human plasma: evidence for novel Abeta species.
|
Proteomics
|
2007
|
0.96
|
|
22
|
The amyloid-beta (Abeta) peptide pattern in cerebrospinal fluid in Alzheimer's disease: evidence of a novel carboxyterminally elongated Abeta peptide.
|
Rapid Commun Mass Spectrom
|
2003
|
0.95
|
|
23
|
Memantine inhibits ethanol-induced NMDA receptor up-regulation in rat hippocampal neurons.
|
Brain Res
|
2005
|
0.95
|
|
24
|
Development of a magnetic immunosorbent for on-chip preconcentration of amyloid β isoforms: Representatives of Alzheimer's disease biomarkers.
|
Biomicrofluidics
|
2012
|
0.88
|
|
25
|
Electrophoretic separation of amyloid beta peptides in plasma.
|
Electrophoresis
|
2004
|
0.87
|
|
26
|
CSF amyloid-β 1-38 and 1-42 in FTD and AD: Biomarker performance critically depends on the detergent accessible fraction.
|
Proteomics Clin Appl
|
2008
|
0.86
|
|
27
|
Cerebrospinal fluid neurochemical phenotypes in vascular dementias: original data and mini-review.
|
Dement Geriatr Cogn Disord
|
2008
|
0.85
|
|
28
|
Tyr687 dependent APP endocytosis and Abeta production.
|
J Mol Neurosci
|
2007
|
0.85
|
|
29
|
cNEUPRO: Novel Biomarkers for Neurodegenerative Diseases.
|
Int J Alzheimers Dis
|
2010
|
0.84
|
|
30
|
Measurement of ERK 1/2 in CSF from patients with neuropsychiatric disorders and evidence for the presence of the activated form.
|
J Alzheimers Dis
|
2009
|
0.84
|
|
31
|
Microchip electrophoresis profiling of Aβ peptides in the cerebrospinal fluid of patients with Alzheimer's disease.
|
Anal Chem
|
2010
|
0.84
|
|
32
|
Recurrent systemic infections with Streptococcus pneumoniae do not aggravate the course of experimental neurodegenerative diseases.
|
J Neurosci Res
|
2010
|
0.82
|
|
33
|
Polymeric complements to the Alzheimer's disease biomarker β-amyloid isoforms Aβ1-40 and Aβ1-42 for blood serum analysis under denaturing conditions.
|
J Am Chem Soc
|
2011
|
0.82
|
|
34
|
A novel mutation P112H in the TARDBP gene associated with frontotemporal lobar degeneration without motor neuron disease and abundant neuritic amyloid plaques.
|
Acta Neuropathol Commun
|
2015
|
0.82
|
|
35
|
Tyrosine 687 phosphorylated Alzheimer's amyloid precursor protein is retained intracellularly and exhibits a decreased turnover rate.
|
Neurodegener Dis
|
2007
|
0.81
|
|
36
|
Cerebrospinal fluid amyloid-β 2-42 is decreased in Alzheimer's, but not in frontotemporal dementia.
|
J Neural Transm (Vienna)
|
2012
|
0.81
|
|
37
|
Characterization of cerebrospinal fluid aminoterminally truncated and oxidized amyloid-β peptides.
|
Proteomics Clin Appl
|
2012
|
0.80
|
|
38
|
Exposure to allergens of different cattle breeds and their relevance in occupational allergy.
|
Int Arch Occup Environ Health
|
2009
|
0.80
|
|
39
|
Cerebrospinal fluid tau, p-tau 181 and amyloid-β38/40/42 in frontotemporal dementias and primary progressive aphasias.
|
Dement Geriatr Cogn Disord
|
2010
|
0.80
|
|
40
|
Long-term stability of Alzheimer's disease biomarker proteins in cerebrospinal fluid.
|
J Alzheimers Dis
|
2011
|
0.80
|
|
41
|
Nonsteroidal anti-inflammatory drugs and ectodomain shedding of the amyloid precursor protein.
|
Neurodegener Dis
|
2008
|
0.78
|
|
42
|
Combined Analysis of CSF Tau, Aβ42, Aβ1-42% and Aβ1-40% in Alzheimer's Disease, Dementia with Lewy Bodies and Parkinson's Disease Dementia.
|
Int J Alzheimers Dis
|
2010
|
0.78
|
|
43
|
Different CSF β-amyloid processing in Alzheimer's and Creutzfeldt-Jakob disease.
|
J Neural Transm (Vienna)
|
2011
|
0.78
|
|
44
|
Adherence-dependent shifts in the patterns of beta-amyloid peptides secreted by human mononuclear phagocytes.
|
Brain Behav Immun
|
2008
|
0.78
|
|
45
|
Stability of amyloid-β peptides in plasma and serum.
|
Electrophoresis
|
2012
|
0.78
|
|
46
|
Aminoterminally truncated and oxidized amyloid-β peptides in the cerebrospinal fluid of Alzheimer's disease patients.
|
J Alzheimers Dis
|
2012
|
0.77
|
|
47
|
Distinct fractional Abeta release patterns in human mononuclear phagocytes.
|
J Neuroimmunol
|
2008
|
0.76
|
|
48
|
Neurochemical biomarkers in Alzheimer's disease and related disorders.
|
Ther Adv Neurol Disord
|
2012
|
0.76
|
|
49
|
Plasma amyloid-beta peptides in acute cerebral ischemia: a pilot study.
|
J Clin Lab Anal
|
2012
|
0.75
|
|
50
|
Analysis of amyloid-β peptides in cerebrospinal fluid samples by capillary electrophoresis coupled with LIF detection.
|
Anal Chem
|
2011
|
0.75
|
|
51
|
Challenges in modern biomarker discovery--17th HUPO BPP workshop: May 24-25, 2012, Sao Paulo, Brazil.
|
Proteomics
|
2013
|
0.75
|