Published in Dev Immunol on September 01, 2002
Exploring the full spectrum of macrophage activation. Nat Rev Immunol (2008) 26.08
Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair. J Clin Invest (2005) 8.58
Biochemical and functional characterization of three activated macrophage populations. J Leukoc Biol (2006) 4.87
Macrophages: master regulators of inflammation and fibrosis. Semin Liver Dis (2010) 4.24
NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 mice. Nature (2012) 3.67
Krüppel-like factor 4 regulates macrophage polarization. J Clin Invest (2011) 3.08
Heterogeneity of microglial activation in the innate immune response in the brain. J Neuroimmune Pharmacol (2009) 3.04
Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor kappaB. Proc Natl Acad Sci U S A (2009) 3.01
Expression profiles for macrophage alternative activation genes in AD and in mouse models of AD. J Neuroinflammation (2006) 2.23
Th2 cytokine-induced alterations in intestinal smooth muscle function depend on alternatively activated macrophages. Gastroenterology (2008) 2.09
Retnla (relmalpha/fizz1) suppresses helminth-induced Th2-type immunity. PLoS Pathog (2009) 2.07
Francisella tularensis live vaccine strain induces macrophage alternative activation as a survival mechanism. J Immunol (2008) 2.06
Control of virus reactivation arrests pulmonary herpesvirus-induced fibrosis in IFN-gamma receptor-deficient mice. Am J Respir Crit Care Med (2007) 2.05
C-C chemokine receptor 2 (CCR2) regulates the hepatic recruitment of myeloid cells that promote obesity-induced hepatic steatosis. Diabetes (2010) 1.86
Temporal pattern of expression and colocalization of microglia/macrophage phenotype markers following brain ischemic injury in mice. J Neuroinflammation (2011) 1.84
Neuroinflammation and M2 microglia: the good, the bad, and the inflamed. J Neuroinflammation (2014) 1.83
Control of RSV-induced lung injury by alternatively activated macrophages is IL-4R alpha-, TLR4-, and IFN-beta-dependent. Mucosal Immunol (2010) 1.78
Retracted The absence of MyD88 has no effect on the induction of alternatively activated macrophage during Fasciola hepatica infection. BMC Immunol (2011) 1.40
In a murine tuberculosis model, the absence of homeostatic chemokines delays granuloma formation and protective immunity. J Immunol (2009) 1.38
Skin wound healing modulation by macrophages. Int J Clin Exp Pathol (2010) 1.34
Revision joint replacement, wear particles, and macrophage polarization. Acta Biomater (2012) 1.21
Sequential expression of macrophage anti-microbial/inflammatory and wound healing markers following innate, alternative and classical activation. Clin Exp Immunol (2010) 1.14
Resistin-like molecule-beta in scleroderma-associated pulmonary hypertension. Am J Respir Cell Mol Biol (2009) 1.12
The immunomodulatory glycan LNFPIII initiates alternative activation of murine macrophages in vivo. Immunology (2008) 1.08
Advanced age impairs macrophage polarization. J Interferon Cytokine Res (2011) 1.04
Rod-like microglia are restricted to eyes with laser-induced ocular hypertension but absent from the microglial changes in the contralateral untreated eye. PLoS One (2013) 1.02
New weapons in the war on worms: identification of putative mechanisms of immune-mediated expulsion of gastrointestinal nematodes. Int J Parasitol (2006) 1.02
Local effect of IL-4 delivery on polyethylene particle induced osteolysis in the murine calvarium. J Biomed Mater Res A (2012) 1.00
HDL induces the expression of the M2 macrophage markers arginase 1 and Fizz-1 in a STAT6-dependent process. PLoS One (2013) 0.99
Macrophage polarization in response to wear particles in vitro. Cell Mol Immunol (2013) 0.99
Arginase in parasitic infections: macrophage activation, immunosuppression, and intracellular signals. J Biomed Biotechnol (2009) 0.98
Mannosyl-recognizing receptors induce an M1-like phenotype in macrophages of susceptible mice but an M2-like phenotype in mice resistant to a fungal infection. PLoS One (2013) 0.92
The increase in mannose receptor recycling favors arginase induction and Trypanosoma cruzi survival in macrophages. Int J Biol Sci (2011) 0.90
Differential macrophage activation alters the expression profile of NTPDase and ecto-5'-nucleotidase. PLoS One (2012) 0.90
Role for parasite genetic diversity in differential host responses to Trypanosoma brucei infection. Infect Immun (2010) 0.88
Three-dimensional confocal analysis of microglia/macrophage markers of polarization in experimental brain injury. J Vis Exp (2013) 0.87
Acute heart inflammation: ultrastructural and functional aspects of macrophages elicited by Trypanosoma cruzi infection. J Cell Mol Med (2008) 0.87
Critical role of regulator G-protein signaling 10 (RGS10) in modulating macrophage M1/M2 activation. PLoS One (2013) 0.86
Programmed death ligand 2 regulates arginase induction and modifies Trypanosoma cruzi survival in macrophages during murine experimental infection. Immunology (2011) 0.85
Selective inhibition and augmentation of alternative macrophage activation by progesterone. Immunology (2011) 0.84
Complement protein C1q promotes macrophage anti-inflammatory M2-like polarization during the clearance of atherogenic lipoproteins. Inflamm Res (2014) 0.82
Extracellular mycobacterial DnaK polarizes macrophages to the M2-like phenotype. PLoS One (2014) 0.81
Interleukin-1 receptor-associated kinase-4 (IRAK4) promotes inflammatory osteolysis by activating osteoclasts and inhibiting formation of foreign body giant cells. J Biol Chem (2014) 0.79
Apolipoprotein E-/- Mice Lacking Hemopexin Develop Increased Atherosclerosis via Mechanisms That Include Oxidative Stress and Altered Macrophage Function. Arterioscler Thromb Vasc Biol (2016) 0.78
Retnla overexpression attenuates allergic inflammation of the airway. PLoS One (2014) 0.78
Proteomic analysis of bronchoalveolar lavage fluid proteins from mice infected with Francisella tularensis ssp. novicida. J Proteome Res (2012) 0.77
Overexpression of the monocyte chemokine CCL2 in dorsal root ganglion neurons causes a conditioning-like increase in neurite outgrowth and does so via a STAT3 dependent mechanism. Exp Neurol (2015) 0.77
Bidirectional crosstalk via IL-6, PGE2 and PGD2 between murine myofibroblasts and alternatively activated macrophages enhances anti-inflammatory phenotype in both cells. Br J Pharmacol (2016) 0.77
Role of Atypical Chemokine Receptors in Microglial Activation and Polarization. Front Aging Neurosci (2017) 0.76
The spleen as an extramedullary source of inflammatory cells responding to acetaminophen-induced liver injury. Toxicol Appl Pharmacol (2016) 0.75
Alkylindole-sensitive receptors modulate microglial cell migration and proliferation. Glia (2015) 0.75
The pathogenesis of chronic eosinophilic esophagitis in SHARPIN-deficient mice. Exp Mol Pathol (2015) 0.75
Evaluating the evidence for macrophage presence in skeletal muscle and its relation to insulin resistance in obese mice and humans: a systematic review protocol. BMC Res Notes (2017) 0.75
Loss of IRF2BP2 in Microglia Increases Inflammation and Functional Deficits after Focal Ischemic Brain Injury. Front Cell Neurosci (2017) 0.75
Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity. Blood (2008) 7.15
Differential expression of FIZZ1 and Ym1 in alternatively versus classically activated macrophages. J Leukoc Biol (2002) 3.89
Tolerance and M2 (alternative) macrophage polarization are related processes orchestrated by p50 nuclear factor kappaB. Proc Natl Acad Sci U S A (2009) 3.01
Macrophage galactose-type C-type lectins as novel markers for alternatively activated macrophages elicited by parasitic infections and allergic airway inflammation. J Leukoc Biol (2004) 2.30
Alternatively activated macrophages during parasite infections. Trends Parasitol (2004) 2.01
Classical and alternative activation of mononuclear phagocytes: picking the best of both worlds for tumor promotion. Immunobiology (2006) 1.96
Reactive oxygen species and 12/15-lipoxygenase contribute to the antiproliferative capacity of alternatively activated myeloid cells elicited during helminth infection. J Immunol (2005) 1.86
The serum resistance-associated gene as a diagnostic tool for the detection of Trypanosoma brucei rhodesiense. Am J Trop Med Hyg (2002) 1.76
Tip-DC development during parasitic infection is regulated by IL-10 and requires CCL2/CCR2, IFN-gamma and MyD88 signaling. PLoS Pathog (2010) 1.70
Peroxisome proliferator-activated receptor gamma (PPARgamma) ligands reverse CTL suppression by alternatively activated (M2) macrophages in cancer. Blood (2006) 1.65
Identification of a common gene signature for type II cytokine-associated myeloid cells elicited in vivo in different pathologic conditions. Blood (2006) 1.43
Myeloid-derived suppressor cells in parasitic infections. Eur J Immunol (2010) 1.36
IL-10 dampens TNF/inducible nitric oxide synthase-producing dendritic cell-mediated pathogenicity during parasitic infection. J Immunol (2009) 1.35
Alternatively activated macrophages in protozoan infections. Curr Opin Immunol (2007) 1.30
Antiprotozoan and Antiviral Activities of Non-cytotoxic Truncated and Variant Analogues of Mussel Defensin. Evid Based Complement Alternat Med (2004) 1.24
Nitric oxide-independent CTL suppression during tumor progression: association with arginase-producing (M2) myeloid cells. J Immunol (2003) 1.23
Secretory leukocyte protease inhibitor promotes the tumorigenic and metastatic potential of cancer cells. Proc Natl Acad Sci U S A (2003) 1.19
Adenylate cyclases of Trypanosoma brucei inhibit the innate immune response of the host. Science (2012) 1.19
Alternatively activated myeloid cells limit pathogenicity associated with African trypanosomiasis through the IL-10 inducible gene selenoprotein P. J Immunol (2008) 1.16
Engineering camel single-domain antibodies and immobilization chemistry for human prostate-specific antigen sensing. Anal Chem (2005) 1.10
African trypanosomiasis: naturally occurring regulatory T cells favor trypanotolerance by limiting pathology associated with sustained type 1 inflammation. J Immunol (2007) 1.09
Domains and maturation processes that regulate the activity of ADAMTS-2, a metalloproteinase cleaving the aminopropeptide of fibrillar procollagens types I-III and V. J Biol Chem (2005) 1.06
Myeloid-derived suppressor cells infiltrate the heart in acute Trypanosoma cruzi infection. J Immunol (2011) 1.05
Pivotal Advance: Arginase-1-independent polyamine production stimulates the expression of IL-4-induced alternatively activated macrophage markers while inhibiting LPS-induced expression of inflammatory genes. J Leukoc Biol (2012) 1.04
High affinity nanobodies against the Trypanosome brucei VSG are potent trypanolytic agents that block endocytosis. PLoS Pathog (2011) 1.01
African trypanosomosis: from immune escape and immunopathology to immune intervention. Vet Parasitol (2007) 0.98
A glycosylphosphatidylinositol-based treatment alleviates trypanosomiasis-associated immunopathology. J Immunol (2007) 0.96
Role of iron homeostasis in trypanosomiasis-associated anemia. Immunobiology (2008) 0.96
Exosites mediate the anti-inflammatory effects of a multifunctional serpin from the saliva of the tick Ixodes ricinus. FEBS J (2009) 0.96
Experimental expansion of the regulatory T cell population increases resistance to African trypanosomiasis. J Infect Dis (2008) 0.95
Infection stage-dependent modulation of macrophage activation in Trypanosoma congolense-resistant and -susceptible mice. Infect Immun (2002) 0.94
Similar inflammatory DC maturation signatures induced by TNF or Trypanosoma brucei antigens instruct default Th2-cell responses. Eur J Immunol (2011) 0.91
IL-10 limits production of pathogenic TNF by M1 myeloid cells through induction of nuclear NF-κB p50 member in Trypanosoma congolense infection-resistant C57BL/6 mice. Eur J Immunol (2011) 0.90
Antagonistic effect of NK cells on alternatively activated monocytes: a contribution of NK cells to CTL generation. Blood (2002) 0.90
Bacterial lipoprotein-based vaccines induce tumor necrosis factor-dependent type 1 protective immunity against Leishmania major. Infect Immun (2002) 0.88
Understanding the role of monocytic cells in liver inflammation using parasite infection as a model. Immunobiology (2009) 0.86
Scrutinizing the mechanisms underlying the induction of anemia of inflammation through GPI-mediated modulation of macrophage activation in a model of African trypanosomiasis. Microbes Infect (2010) 0.86
The central role of macrophages in trypanosomiasis-associated anemia: rationale for therapeutical approaches. Endocr Metab Immune Disord Drug Targets (2010) 0.84
Heavy-chain only antibodies derived from dromedary are secreted and displayed by mouse B cells. Immunology (2003) 0.83
Identification of a parasitic immunomodulatory protein triggering the development of suppressive M1 macrophages during African trypanosomiasis. J Infect Dis (2009) 0.83
Origin and functional diversification of an amphibian defense peptide arsenal. PLoS Genet (2013) 0.83
A Trypanosoma brucei kinesin heavy chain promotes parasite growth by triggering host arginase activity. PLoS Pathog (2013) 0.82
The CD20 homolog Ms4a8a integrates pro- and anti-inflammatory signals in novel M2-like macrophages and is expressed in parasite infection. Eur J Immunol (2012) 0.81
N-terminal truncation enables crystallization of the receptor-binding domain of the FedF bacterial adhesin. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.81
Evidence for proteins involved in prophenoloxidase cascade Eisenia fetida earthworms. J Comp Physiol B (2006) 0.81
Relationship between hemolytic molecules in Eisenia fetida earthworms. Dev Comp Immunol (2005) 0.80
Both type-I and type-II responses contribute to murine trypanotolerance. J Vet Med Sci (2009) 0.79
Comparative study of the CCF-like pattern recognition protein in different Lumbricid species. Dev Comp Immunol (2005) 0.78
Effect of experimental microbial challenge on the expression of defense molecules in Eisenia foetida earthworm. Dev Comp Immunol (2004) 0.77
The metastatic T-cell hybridoma antigen/P-selectin glycoprotein ligand 1 is required for hematogenous metastasis of lymphomas. Int J Cancer (2007) 0.77
An invertebrate TNF functional analogue activates macrophages via lectin-saccharide interaction with ion channels. Int Immunol (2006) 0.77
Ablation of NK cell function during tumor growth favors Type 2-associated macrophages, leading to suppressed CTL generation. Clin Dev Immunol (2004) 0.77
CCF, an invertebrate analogue of TNF, is not related to the other lytic components from Eisenia foetida earthworm. Bioessays (2002) 0.75
Trypanosoma cruzi is lysed by coelomic cytolytic factor-1, an invertebrate analogue of tumor necrosis factor, and induces phenoloxidase activity in the coelomic fluid of Eisenia foetida foetida. Dev Comp Immunol (2002) 0.75
Characterization of the interaction between murine tumour necrosis factor and monoclonal antibodies. Cytokine (2002) 0.75
Advances in immunology and vaccine discovery report of the United States-European Commission workshop. Vaccine (2007) 0.75
An invertebrate defense molecule activates membrane conductance in mammalian cells by means of its lectin-like domain. Dev Comp Immunol (2002) 0.75
Quantitative differences in immune responses in mouse strains that differ in their susceptibility to Trypanosoma brucei brucei infection. J Vet Med Sci (2009) 0.75