Published in J Cell Sci on September 01, 2003
Organelles and trafficking machinery for postsynaptic plasticity. Annu Rev Neurosci (2006) 2.82
The structure of the myosin VI motor reveals the mechanism of directionality reversal. Nature (2005) 2.50
Myosin-1a is critical for normal brush border structure and composition. Mol Biol Cell (2005) 2.44
Myosin VI and vinculin cooperate during the morphogenesis of cadherin cell cell contacts in mammalian epithelial cells. J Cell Biol (2007) 2.02
The molecular pharmacology and cell biology of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors. Pharmacol Rev (2005) 1.96
A role for myosin VI in postsynaptic structure and glutamate receptor endocytosis. J Cell Biol (2005) 1.90
GIPC is recruited by APPL to peripheral TrkA endosomes and regulates TrkA trafficking and signaling. Mol Cell Biol (2006) 1.85
Binding of internalized receptors to the PDZ domain of GIPC/synectin recruits myosin VI to endocytic vesicles. Proc Natl Acad Sci U S A (2006) 1.68
A novel role of myosin VI in human prostate cancer. Am J Pathol (2006) 1.59
Myosin VI walks "wiggly" on actin with large and variable tilting. Mol Cell (2007) 1.54
Internalization of large double-membrane intercellular vesicles by a clathrin-dependent endocytic process. Mol Biol Cell (2006) 1.46
Uncoated endocytic vesicles require the unconventional myosin, Myo6, for rapid transport through actin barriers. Mol Biol Cell (2004) 1.43
Molecular structure, function, and dynamics of clathrin-mediated membrane traffic. Cold Spring Harb Perspect Biol (2014) 1.41
Neuropilins are multifunctional coreceptors involved in tumor initiation, growth, metastasis and immunity. Oncotarget (2012) 1.37
Endocytic trafficking of CFTR in health and disease. J Cyst Fibros (2006) 1.36
GLUT1CBP(TIP2/GIPC1) interactions with GLUT1 and myosin VI: evidence supporting an adapter function for GLUT1CBP. Mol Biol Cell (2005) 1.35
The NHE3 juxtamembrane cytoplasmic domain directly binds ezrin: dual role in NHE3 trafficking and mobility in the brush border. Mol Biol Cell (2006) 1.34
Cargo binding induces dimerization of myosin VI. Proc Natl Acad Sci U S A (2009) 1.34
Myosin VI: an innovative motor that challenged the swinging lever arm hypothesis. Nat Rev Mol Cell Biol (2010) 1.27
Cargo-binding makes a wild-type single-headed myosin-VI move processively. Biophys J (2006) 1.27
The myosin superfamily at a glance. J Cell Sci (2012) 1.23
A PDZ-binding motif as a critical determinant of Rho guanine exchange factor function and cell phenotype. Mol Biol Cell (2006) 1.19
Actin dynamics in growth cone motility and navigation. J Neurochem (2013) 1.16
A role for myosin VI in the localization of axonal proteins. PLoS Biol (2011) 1.14
Myosin motor function: the ins and outs of actin-based membrane protrusions. Cell Mol Life Sci (2010) 1.12
Different subcellular localizations and functions of Arabidopsis myosin VIII. BMC Plant Biol (2008) 1.11
Coupled myosin VI motors facilitate unidirectional movement on an F-actin network. J Cell Biol (2009) 1.06
Type II transforming growth factor-beta receptor recycling is dependent upon the clathrin adaptor protein Dab2. Mol Biol Cell (2010) 1.06
Myosin-Va regulates exocytosis through the submicromolar Ca2+-dependent binding of syntaxin-1A. Mol Biol Cell (2005) 1.05
Myosin VI is a mediator of the p53-dependent cell survival pathway. Mol Cell Biol (2006) 1.04
Aminoglycoside-induced phosphatidylserine externalization in sensory hair cells is regionally restricted, rapid, and reversible. J Neurosci (2008) 1.04
A WASp-binding type II phosphatidylinositol 4-kinase required for actin polymerization-driven endosome motility. J Cell Biol (2005) 1.02
A network of networks: cytoskeletal control of compartmentalized function within dendritic spines. Curr Opin Neurobiol (2010) 0.99
Postsynaptic scaffold proteins at non-synaptic sites. The role of postsynaptic scaffold proteins in motor-protein-receptor complexes. EMBO Rep (2005) 0.98
Targeting GIPC/synectin in pancreatic cancer inhibits tumor growth. Clin Cancer Res (2009) 0.96
Molecular mechanisms of receptor-mediated endocytosis in the renal proximal tubular epithelium. J Biomed Biotechnol (2010) 0.95
Gipc1 has a dual role in Vangl2 trafficking and hair bundle integrity in the inner ear. Development (2012) 0.93
Myosin VI must dimerize and deploy its unusual lever arm in order to perform its cellular roles. Cell Rep (2014) 0.90
Migrating with myosin VI. Am J Pathol (2006) 0.90
The cortical acto-Myosin network: from diffusion barrier to functional gateway in the transport of neurosecretory vesicles to the plasma membrane. Front Endocrinol (Lausanne) (2013) 0.90
A combined transgenic proteomic analysis and regulated trafficking of neuroligin-2. J Biol Chem (2014) 0.89
Myosins in cell junctions. Bioarchitecture (2012) 0.89
Altered renal proximal tubular endocytosis and histology in mice lacking myosin-VI. Cytoskeleton (Hoboken) (2010) 0.89
Negative regulation of the endocytic adaptor disabled-2 (Dab2) in mitosis. J Biol Chem (2010) 0.89
Multifunctional myosin VI has a multitude of cargoes. Proc Natl Acad Sci U S A (2011) 0.88
The Drosophila GIPC homologue can modulate myosin based processes and planar cell polarity but is not essential for development. PLoS One (2010) 0.87
Dynamic exchange of myosin VI on endocytic structures. J Biol Chem (2012) 0.86
The endocytic receptor megalin and its associated proteins in proximal tubule epithelial cells. Membranes (Basel) (2014) 0.86
Kinetic properties and small-molecule inhibition of human myosin-6. FEBS Lett (2012) 0.85
Microarray analysis of E9.5 reduced folate carrier (RFC1; Slc19a1) knockout embryos reveals altered expression of genes in the cubilin-megalin multiligand endocytic receptor complex. BMC Genomics (2008) 0.83
Structural and functional insights on the Myosin superfamily. Bioinform Biol Insights (2012) 0.83
Drosophila CLIP-190 and mammalian CLIP-170 display reduced microtubule plus end association in the nervous system. Mol Biol Cell (2015) 0.82
GIPC1 interacts with MyoGEF and promotes MDA-MB-231 breast cancer cell invasion. J Biol Chem (2010) 0.81
C-Fos elimination compensates for disabled-2 requirement in mouse extraembryonic endoderm development. Dev Dyn (2009) 0.81
Myosin VI and VIIa distribution among inner ear epithelia in diverse fishes. Hear Res (2007) 0.80
Structure, sulfatide binding properties, and inhibition of platelet aggregation by a disabled-2 protein-derived peptide. J Biol Chem (2012) 0.80
Myosin VI mediates the movement of NHE3 down the microvillus in intestinal epithelial cells. J Cell Sci (2014) 0.79
Adaptive evolution of the myo6 gene in old world fruit bats (family: pteropodidae). PLoS One (2013) 0.79
Myosin VI reduces proliferation, but not differentiation, in pluripotent P19 cells. PLoS One (2013) 0.79
Hormonal induction and roles of Disabled-2 in lactation and involution. PLoS One (2014) 0.78
Myosin VI is differentially regulated by DNA damage in p53- and cell type-dependent manners. J Biol Chem (2010) 0.78
Myosinome: a database of myosins from select eukaryotic genomes to facilitate analysis of sequence-structure-function relationships. Bioinform Biol Insights (2012) 0.77
Myosin VI and Associated Proteins Are Expressed in Human Macrophages but Do Not Play a Role in Foam Cell Formation in THP-1 Cells. Int J Vasc Med (2013) 0.77
Molecular mechanisms regulating formation, trafficking and processing of annular gap junctions. BMC Cell Biol (2016) 0.76
Analysis of the membrane proteome of ciprofloxacin-resistant macrophages by stable isotope labeling with amino acids in cell culture (SILAC). PLoS One (2013) 0.76
Neuropilin-1 is a receptor for extracellular miRNA and AGO2/miRNA complexes and mediates the internalization of miRNAs that modulate cell function. Oncotarget (2016) 0.76
Tocotrienols induce endoplasmic reticulum stress and apoptosis in cervical cancer cells. Genes Nutr (2016) 0.75
Endocytosis and Physiology: Insights from Disabled-2 Deficient Mice. Front Cell Dev Biol (2016) 0.75
Diverse functions of myosin VI elucidated by an isoform-specific α-helix domain. Nat Struct Mol Biol (2016) 0.75