Published in J Neurochem on November 17, 2013
A dynamic formin-dependent deep F-actin network in axons. J Cell Biol (2015) 1.01
The axonal cytoskeleton: from organization to function. Front Mol Neurosci (2015) 0.96
Sculpting Neural Circuits by Axon and Dendrite Pruning. Annu Rev Cell Dev Biol (2015) 0.91
Promoting filopodial elongation in neurons by membrane-bound magnetic nanoparticles. Nanomedicine (2015) 0.86
The role of Arp2/3 in growth cone actin dynamics and guidance is substrate dependent. J Neurosci (2014) 0.85
TRPM7 Regulates Axonal Outgrowth and Maturation of Primary Hippocampal Neurons. Mol Neurobiol (2014) 0.85
CRMP4 and CRMP2 Interact to Coordinate Cytoskeleton Dynamics, Regulating Growth Cone Development and Axon Elongation. Neural Plast (2015) 0.85
Drosophila Imp iCLIP identifies an RNA assemblage coordinating F-actin formation. Genome Biol (2015) 0.83
Chatting with the neighbors: crosstalk between Rho-kinase (ROCK) and other signaling pathways for treatment of neurological disorders. Front Neurosci (2015) 0.81
Src and cortactin promote lamellipodia protrusion and filopodia formation and stability in growth cones. Mol Biol Cell (2015) 0.80
Mechanochemical regulation of growth cone motility. Front Cell Neurosci (2015) 0.80
Building Blocks of Functioning Brain: Cytoskeletal Dynamics in Neuronal Development. Int Rev Cell Mol Biol (2016) 0.80
Using Xenopus laevis retinal and spinal neurons to study mechanisms of axon guidance in vivo and in vitro. Semin Cell Dev Biol (2016) 0.79
Anchoring of protein kinase A by ERM (ezrin-radixin-moesin) proteins is required for proper netrin signaling through DCC (deleted in colorectal cancer). J Biol Chem (2015) 0.79
A requirement for filopodia extension toward Slit during Robo-mediated axon repulsion. J Cell Biol (2016) 0.78
Quantifying mechanical force in axonal growth and guidance. Front Cell Neurosci (2015) 0.77
Role of tropomodulin's leucine rich repeat domain in the formation of neurite-like processes. Biochemistry (2014) 0.77
Xenopus laevis as a model system to study cytoskeletal dynamics during axon pathfinding. Genesis (2017) 0.77
The discovery of the growth cone and its influence on the study of axon guidance. Front Neuroanat (2015) 0.76
Wnt Signalling Promotes Actin Dynamics during Axon Remodelling through the Actin-Binding Protein Eps8. PLoS One (2015) 0.76
Cdc42 and RhoA reveal different spatio-temporal dynamics upon local stimulation with Semaphorin-3A. Front Cell Neurosci (2015) 0.75
Sevoflurane Impairs Growth Cone Motility in Dissociated Murine Neurons. J Neurosurg Anesthesiol (2016) 0.75
Aerobic exercise regulates Rho/cofilin pathways to rescue synaptic loss in aged rats. PLoS One (2017) 0.75
Division of labor in the growth cone by DSCR1. J Cell Biol (2016) 0.75
Disruption of ArhGAP15 results in hyperactive Rac1, affects the architecture and function of hippocampal inhibitory neurons and causes cognitive deficits. Sci Rep (2016) 0.75
The Arp2/3 complex is essential at multiple stages of neural development. Neurogenesis (Austin) (2016) 0.75
FLIM FRET Visualization of Cdc42 Activation by Netrin-1 in Embryonic Spinal Commissural Neuron Growth Cones. PLoS One (2016) 0.75
Rat embryonic hippocampus and induced pluripotent stem cell derived cultured neurons recover from laser-induced subaxotomy. Neurophotonics (2015) 0.75
The RNA Binding Protein Igf2bp1 Is Required for Zebrafish RGC Axon Outgrowth In Vivo. PLoS One (2015) 0.75
The sense is in the fingertips: The distal end controls filopodial mechanics and dynamics in response to external stimuli. Commun Integr Biol (2013) 0.75
Local Arp2/3 dependent actin assembly modulates applied traction force during apCAM adhesion site maturation. Mol Biol Cell (2016) 0.75
Slippery signaling: Palmitoylation-dependent control of neuronal kinase localization and activity. Mol Membr Biol (2016) 0.75
Distinctive Effects of Cytochalasin B in Chick Primary Myoblasts and Fibroblasts. PLoS One (2016) 0.75
Traction force and tension fluctuations in growing axons. Front Cell Neurosci (2015) 0.75
Katanin p60 promotes neurite growth and collateral formation in the hippocampus. Int J Clin Exp Med (2014) 0.75
Tropomodulin isoforms utilize specific binding functions to modulate dendrite development. Cytoskeleton (Hoboken) (2016) 0.75
Actin regulation by tropomodulin and tropomyosin in neuronal morphogenesis and function. Mol Cell Neurosci (2017) 0.75
Amplification of F-Actin Disassembly and Cellular Repulsion by Growth Factor Signaling. Dev Cell (2017) 0.75
Cellular motility driven by assembly and disassembly of actin filaments. Cell (2003) 26.05
Rho GTPases in cell biology. Nature (2002) 22.81
Focal adhesion kinase: in command and control of cell motility. Nat Rev Mol Cell Biol (2005) 11.74
Molecular mechanisms controlling actin filament dynamics in nonmuscle cells. Annu Rev Biophys Biomol Struct (2000) 10.11
Antagonism between Ena/VASP proteins and actin filament capping regulates fibroblast motility. Cell (2002) 6.80
Actin polymerization and its regulation by proteins from nonmuscle cells. Physiol Rev (1982) 6.47
Cytoskeletal dynamics and transport in growth cone motility and axon guidance. Neuron (2003) 5.19
The Talin head domain binds to integrin beta subunit cytoplasmic tails and regulates integrin activation. J Biol Chem (1999) 4.92
Traction dynamics of filopodia on compliant substrates. Science (2008) 4.57
Control of the assembly of ATP- and ADP-actin by formins and profilin. Cell (2006) 4.37
Rho GTPases in neuronal morphogenesis. Nat Rev Neurosci (2000) 4.33
Calpain-mediated proteolysis of talin regulates adhesion dynamics. Nat Cell Biol (2004) 4.29
Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex. Nat Cell Biol (2002) 4.29
Formin is a processive motor that requires profilin to accelerate actin assembly and associated ATP hydrolysis. Cell (2004) 4.01
Myosin II functions in actin-bundle turnover in neuronal growth cones. Nat Cell Biol (2006) 3.91
Inhibition of lysophosphatidate- and thrombin-induced neurite retraction and neuronal cell rounding by ADP ribosylation of the small GTP-binding protein Rho. J Cell Biol (1994) 3.65
Talin depletion reveals independence of initial cell spreading from integrin activation and traction. Nat Cell Biol (2008) 3.62
Signal transduction in neuronal migration: roles of GTPase activating proteins and the small GTPase Cdc42 in the Slit-Robo pathway. Cell (2001) 3.44
Conversion of neuronal growth cone responses from repulsion to attraction by cyclic nucleotides. Science (1998) 3.42
The trip of the tip: understanding the growth cone machinery. Nat Rev Mol Cell Biol (2009) 3.38
Myosin drives retrograde F-actin flow in neuronal growth cones. Neuron (1996) 3.33
Local calcium signaling in neurons. Neuron (2003) 3.33
EphA receptors regulate growth cone dynamics through the novel guanine nucleotide exchange factor ephexin. Cell (2001) 3.20
Activation of EphA2 kinase suppresses integrin function and causes focal-adhesion-kinase dephosphorylation. Nat Cell Biol (2000) 3.09
Turning of nerve growth cones induced by neurotransmitters. Nature (1994) 3.06
Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity. J Cell Sci (2002) 2.91
Integrins in cell migration--the actin connection. J Cell Sci (2009) 2.88
Semaphorin 7A promotes axon outgrowth through integrins and MAPKs. Nature (2003) 2.87
Rac-dependent trans-endocytosis of ephrinBs regulates Eph-ephrin contact repulsion. Nat Cell Biol (2003) 2.79
Essential role of TRPC channels in the guidance of nerve growth cones by brain-derived neurotrophic factor. Nature (2005) 2.78
The Ig superfamily cell adhesion molecule, apCAM, mediates growth cone steering by substrate-cytoskeletal coupling. J Cell Biol (1998) 2.66
Plexin-B1 directly interacts with PDZ-RhoGEF/LARG to regulate RhoA and growth cone morphology. Neuron (2002) 2.59
Cell-to-substratum adhesion and guidance of axonal elongation. Dev Biol (1975) 2.47
Requirement of TRPC channels in netrin-1-induced chemotropic turning of nerve growth cones. Nature (2005) 2.42
An SH3 domain-containing GTPase-activating protein for Rho and Cdc42 associates with focal adhesion kinase. Mol Cell Biol (1996) 2.38
New insights into the regulation and cellular functions of the ARP2/3 complex. Nat Rev Mol Cell Biol (2012) 2.25
The growth cone cytoskeleton in axon outgrowth and guidance. Cold Spring Harb Perspect Biol (2011) 2.22
Polymer motors: pushing out the front and pulling up the back. Curr Biol (2003) 2.20
Rho and Ras GTPases in axon growth, guidance, and branching. Cold Spring Harb Perspect Biol (2010) 2.17
The clutch hypothesis revisited: ascribing the roles of actin-associated proteins in filopodial protrusion in the nerve growth cone. J Neurobiol (2000) 2.16
Recognition of the neural chemoattractant Netrin-1 by integrins alpha6beta4 and alpha3beta1 regulates epithelial cell adhesion and migration. Dev Cell (2003) 2.08
Myosin VI: two distinct roles in endocytosis. J Cell Sci (2003) 2.06
Rho proteins, mental retardation and the cellular basis of cognition. Trends Neurosci (2002) 2.06
Control of actin assembly dynamics in cell motility. J Biol Chem (2007) 2.03
The co-workers of actin filaments: from cell structures to signals. Nat Rev Mol Cell Biol (2004) 2.01
Activation of ERM proteins in vivo by Rho involves phosphatidyl-inositol 4-phosphate 5-kinase and not ROCK kinases. Curr Biol (1999) 2.00
Sonic hedgehog guides axons through a noncanonical, Src-family-kinase-dependent signaling pathway. Neuron (2009) 1.99
Nogo-A and myelin-associated glycoprotein mediate neurite growth inhibition by antagonistic regulation of RhoA and Rac1. J Neurosci (2002) 1.99
IRSp53: crossing the road of membrane and actin dynamics in the formation of membrane protrusions. Trends Cell Biol (2008) 1.99
Guiding neuronal growth cones using Ca2+ signals. Trends Cell Biol (2004) 1.97
Signal transduction underlying growth cone guidance by diffusible factors. Curr Opin Neurobiol (1999) 1.92
Clustering of VASP actively drives processive, WH2 domain-mediated actin filament elongation. EMBO J (2008) 1.90
Activation of FAK and Src are receptor-proximal events required for netrin signaling. Nat Neurosci (2004) 1.89
Purification of pseudopodia from polarized cells reveals redistribution and activation of Rac through assembly of a CAS/Crk scaffold. J Cell Biol (2002) 1.87
The molecular basis for calcium-dependent axon pathfinding. Nat Rev Neurosci (2006) 1.87
Signalling and crosstalk of Rho GTPases in mediating axon guidance. Nat Cell Biol (2003) 1.84
RhoA-kinase and myosin II are required for the maintenance of growth cone polarity and guidance by nerve growth factor. J Neurobiol (2006) 1.79
Differences in the organization of actin in the growth cones compared with the neurites of cultured neurons from chick embryos. J Cell Biol (1983) 1.78
Contingent phosphorylation/dephosphorylation provides a mechanism of molecular memory in WASP. Mol Cell (2003) 1.77
Regulation of the neuronal actin cytoskeleton by ADF/cofilin. J Neurobiol (2004) 1.76
Control of axonal branching and synapse formation by focal adhesion kinase. Nat Neurosci (2004) 1.74
Actin-binding proteins take the reins in growth cones. Nat Rev Neurosci (2008) 1.73
Rac1 and RhoA promote neurite outgrowth through formation and stabilization of growth cone point contacts. J Neurosci (2006) 1.71
Targeting of the F-actin-binding protein drebrin by the microtubule plus-tip protein EB3 is required for neuritogenesis. Nat Cell Biol (2008) 1.70
Antagonistic regulation of actin dynamics and cell motility by TRPC5 and TRPC6 channels. Sci Signal (2010) 1.70
Substrate-cytoskeletal coupling as a mechanism for the regulation of growth cone motility and guidance. J Neurobiol (2000) 1.67
Phospholipase C-gamma and phosphoinositide 3-kinase mediate cytoplasmic signaling in nerve growth cone guidance. Neuron (1999) 1.65
Wnt5a induces simultaneous cortical axon outgrowth and repulsive axon guidance through distinct signaling mechanisms. J Neurosci (2009) 1.59
Focal adhesion kinase signaling at sites of integrin-mediated adhesion controls axon pathfinding. Nat Neurosci (2006) 1.59
Growth cone travel in space and time: the cellular ensemble of cytoskeleton, adhesion, and membrane. Neuron (2012) 1.58
Control of axon elongation via an SDF-1alpha/Rho/mDia pathway in cultured cerebellar granule neurons. J Cell Biol (2003) 1.58
Laminin stimulates and guides axonal outgrowth via growth cone myosin II activity. Nat Neurosci (2005) 1.58
Rac1-mediated endocytosis during ephrin-A2- and semaphorin 3A-induced growth cone collapse. J Neurosci (2002) 1.55
Rho GTPases regulate axon growth through convergent and divergent signaling pathways. Neuron (2004) 1.55
XTRPC1-dependent chemotropic guidance of neuronal growth cones. Nat Neurosci (2005) 1.55
Regulation of rho GTPases by crosstalk and neuronal activity in vivo. Neuron (2002) 1.52
Human genetic disorders of axon guidance. Cold Spring Harb Perspect Biol (2010) 1.49
Strength in the periphery: growth cone biomechanics and substrate rigidity response in peripheral and central nervous system neurons. Biophys J (2012) 1.48
Focal loss of actin bundles causes microtubule redistribution and growth cone turning. J Cell Biol (2002) 1.47
Filopodial calcium transients regulate growth cone motility and guidance through local activation of calpain. Neuron (2003) 1.42
Immunocytochemical evidence for colocalization in neurite growth cones of actin and myosin and their relationship to cell--substratum adhesions. Dev Biol (1981) 1.39
A molecular clutch between the actin flow and N-cadherin adhesions drives growth cone migration. J Neurosci (2008) 1.38
The role of formins in filopodia formation. Biochim Biophys Acta (2009) 1.37
Deleted in colorectal cancer binding netrin-1 mediates cell substrate adhesion and recruits Cdc42, Rac1, Pak1, and N-WASP into an intracellular signaling complex that promotes growth cone expansion. J Neurosci (2005) 1.36
Cortactin: a multifunctional regulator of cellular invasiveness. Cell Adh Migr (2011) 1.36
Trio mediates netrin-1-induced Rac1 activation in axon outgrowth and guidance. Mol Cell Biol (2008) 1.32
Src family kinases are involved in EphA receptor-mediated retinal axon guidance. J Neurosci (2004) 1.29
Cell-substratum adhesion of neurite growth cones, and its role in neurite elongation. Exp Cell Res (1979) 1.28
Mouse ACF7 and drosophila short stop modulate filopodia formation and microtubule organisation during neuronal growth. J Cell Sci (2009) 1.28
Myosin-X: a MyTH-FERM myosin at the tips of filopodia. J Cell Sci (2011) 1.27
Regulation of axonal outgrowth and pathfinding by integrin-ECM interactions. Dev Neurobiol (2011) 1.27
Ca2+ influx through mechanosensitive channels inhibits neurite outgrowth in opposition to other influx pathways and release from intracellular stores. J Neurosci (2006) 1.25
Ca2+-dependent regulation of rho GTPases triggers turning of nerve growth cones. J Neurosci (2005) 1.25
Talin and vinculin play distinct roles in filopodial motility in the neuronal growth cone. J Cell Biol (1996) 1.23
Filopodia initiation: focus on the Arp2/3 complex and formins. Cell Adh Migr (2011) 1.23
Multi-level molecular clutches in motile cell processes. Trends Cell Biol (2009) 1.23
Calcium mediates bidirectional growth cone turning induced by myelin-associated glycoprotein. Neuron (2004) 1.20
Microtubule-binding proteins CLASP1 and CLASP2 interact with actin filaments. Cell Motil Cytoskeleton (2007) 1.19
Spatial and temporal second messenger codes for growth cone turning. Proc Natl Acad Sci U S A (2011) 1.18
Measurements of spatiotemporal changes in G-actin concentration reveal its effect on stimulus-induced actin assembly and lamellipodium extension. J Cell Biol (2011) 1.17
Regulation of growth cone actin filaments by guidance cues. J Neurobiol (2004) 2.20
Rac1-mediated endocytosis during ephrin-A2- and semaphorin 3A-induced growth cone collapse. J Neurosci (2002) 1.55
Calcium-dependent interaction of Lis1 with IQGAP1 and Cdc42 promotes neuronal motility. Nat Neurosci (2005) 1.41
Disregulated RhoGTPases and actin cytoskeleton contribute to the migration defect in Lis1-deficient neurons. J Neurosci (2003) 1.38
p75 neurotrophin receptor signaling regulates growth cone filopodial dynamics through modulating RhoA activity. J Neurosci (2004) 1.37
Protein synthesis in distal axons is not required for growth cone responses to guidance cues. J Neurosci (2009) 1.35
Nerve growth factor and semaphorin 3A signaling pathways interact in regulating sensory neuronal growth cone motility. J Neurosci (2002) 1.35
Growth cones turn and migrate up an immobilized gradient of the laminin IKVAV peptide. J Neurobiol (2005) 1.26
Actin turnover is required to prevent axon retraction driven by endogenous actomyosin contractility. J Cell Biol (2002) 1.23
Brain-derived neurotrophic factor regulation of retinal growth cone filopodial dynamics is mediated through actin depolymerizing factor/cofilin. J Neurosci (2004) 1.20
Cdc42 participates in the regulation of ADF/cofilin and retinal growth cone filopodia by brain derived neurotrophic factor. J Neurobiol (2006) 1.17
Changes within maturing neurons limit axonal regeneration in the developing spinal cord. J Neurobiol (2006) 1.14
Activation of ADF/cofilin mediates attractive growth cone turning toward nerve growth factor and netrin-1. Dev Neurobiol (2010) 1.09
Growth cones integrate signaling from multiple guidance cues. J Histochem Cytochem (2003) 0.98
Activation of ezrin/radixin/moesin mediates attractive growth cone guidance through regulation of growth cone actin and adhesion receptors. J Neurosci (2012) 0.97
Modifier of cell adhesion regulates N-cadherin-mediated cell-cell adhesion and neurite outgrowth. J Neurosci (2005) 0.90
L1, beta1 integrin, and cadherins mediate axonal regeneration in the embryonic spinal cord. J Neurobiol (2006) 0.85
The role of Arp2/3 in growth cone actin dynamics and guidance is substrate dependent. J Neurosci (2014) 0.85
Temporal regulation of neuropilin-1 expression and sensitivity to semaphorin 3A in NGF- and NT3-responsive chick sensory neurons. J Neurobiol (2002) 0.84
Protein synthesis in distal axons is not required for axon growth in the embryonic spinal cord. Dev Neurobiol (2007) 0.81
Transient PKA activity is required for initiation but not maintenance of BDNF-mediated protection from nitric oxide-induced growth-cone collapse. J Neurosci (2002) 0.81
Labeling F-actin barbed ends with rhodamine-actin in permeabilized neuronal growth cones. J Vis Exp (2011) 0.79
Repulsive axon guidance cues ephrin-A2 and slit3 stop protrusion of the growth cone leading margin concurrently with inhibition of ADF/cofilin and ERM proteins. Cytoskeleton (Hoboken) (2012) 0.76