Karen Skorupski

Author PubWeight™ 29.35‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Parallel quorum sensing systems converge to regulate virulence in Vibrio cholerae. Cell 2002 5.12
2 Regulation of virulence gene expression in Vibrio cholerae by quorum sensing: HapR functions at the aphA promoter. Mol Microbiol 2002 2.69
3 The alternative sigma factor sigma(E) plays an important role in intestinal survival and virulence in Vibrio cholerae. Infect Immun 2002 2.04
4 Dual regulation of genes involved in acetoin biosynthesis and motility/biofilm formation by the virulence activator AphA and the acetate-responsive LysR-type regulator AlsR in Vibrio cholerae. Mol Microbiol 2005 1.78
5 The crystal structure of AphB, a virulence gene activator from Vibrio cholerae, reveals residues that influence its response to oxygen and pH. Mol Microbiol 2012 1.64
6 Structure of Vibrio cholerae ToxT reveals a mechanism for fatty acid regulation of virulence genes. Proc Natl Acad Sci U S A 2010 1.46
7 The virulence activator AphA links quorum sensing to pathogenesis and physiology in Vibrio cholerae by repressing the expression of a penicillin amidase gene on the small chromosome. J Bacteriol 2003 1.45
8 Vibrio cholerae AphA uses a novel mechanism for virulence gene activation that involves interaction with the LysR-type regulator AphB at the tcpPH promoter. Mol Microbiol 2004 1.37
9 Crystal structure of the Vibrio cholerae quorum-sensing regulatory protein HapR. J Bacteriol 2007 1.32
10 The LysR-type virulence activator AphB regulates the expression of genes in Vibrio cholerae in response to low pH and anaerobiosis. J Bacteriol 2010 1.32
11 The quorum sensing regulator HapR downregulates the expression of the virulence gene transcription factor AphA in Vibrio cholerae by antagonizing Lrp- and VpsR-mediated activation. Mol Microbiol 2007 1.30
12 Requirements for Vibrio cholerae HapR binding and transcriptional repression at the hapR promoter are distinct from those at the aphA promoter. J Bacteriol 2005 1.23
13 Crystal structure of the virulence gene activator AphA from Vibrio cholerae reveals it is a novel member of the winged helix transcription factor superfamily. J Biol Chem 2005 1.21
14 Integration host factor positively regulates virulence gene expression in Vibrio cholerae. J Bacteriol 2008 1.14
15 Binding site requirements of the virulence gene regulator AphB: differential affinities for the Vibrio cholerae classical and El Tor tcpPH promoters. Mol Microbiol 2002 1.06
16 H-NS binding and repression of the ctx promoter in Vibrio cholerae. J Bacteriol 2010 1.01
17 Levels of the secreted Vibrio cholerae attachment factor GbpA are modulated by quorum-sensing-induced proteolysis. J Bacteriol 2009 0.98
18 Role of FlgT in anchoring the flagellum of Vibrio cholerae. J Bacteriol 2010 0.87
19 Characterization of BreR interaction with the bile response promoters breAB and breR in Vibrio cholerae. J Bacteriol 2012 0.78
20 Identification of a Small Molecule Activator for AphB, a LysR-Type Virulence Transcriptional Regulator in Vibrio cholerae. Biochemistry 2017 0.75