Published in Biostatistics on January 01, 2003
Powerful SNP-set analysis for case-control genome-wide association studies. Am J Hum Genet (2010) 6.60
A powerful and flexible multilocus association test for quantitative traits. Am J Hum Genet (2008) 4.96
Optimal tests for rare variant effects in sequencing association studies. Biostatistics (2012) 4.69
Semiparametric regression of multidimensional genetic pathway data: least-squares kernel machines and linear mixed models. Biometrics (2007) 4.66
Estimation and testing for the effect of a genetic pathway on a disease outcome using logistic kernel machine regression via logistic mixed models. BMC Bioinformatics (2008) 3.70
Haplotype-based association analysis via variance-components score test. Am J Hum Genet (2007) 2.93
Sequence kernel association tests for the combined effect of rare and common variants. Am J Hum Genet (2013) 2.41
SNP set association analysis for familial data. Genet Epidemiol (2012) 2.08
General framework for meta-analysis of rare variants in sequencing association studies. Am J Hum Genet (2013) 1.86
Studying gene and gene-environment effects of uncommon and common variants on continuous traits: a marker-set approach using gene-trait similarity regression. Am J Hum Genet (2011) 1.71
Family-based association tests for sequence data, and comparisons with population-based association tests. Eur J Hum Genet (2013) 1.55
A general class of pattern mixture models for nonignorable dropout with many possible dropout times. Biometrics (2007) 1.41
Semiparametric regression during 2003-2007. Electron J Stat (2009) 1.38
A unified mixed-effects model for rare-variant association in sequencing studies. Genet Epidemiol (2013) 1.29
Test for interactions between a genetic marker set and environment in generalized linear models. Biostatistics (2013) 1.20
Insights into pancreatic cancer etiology from pathway analysis of genome-wide association study data. PLoS One (2012) 1.19
Smoothing spline-based score tests for proportional hazards models. Biometrics (2006) 1.14
Haplotype kernel association test as a powerful method to identify chromosomal regions harboring uncommon causal variants. Genet Epidemiol (2013) 1.04
Region-based association analysis of human quantitative traits in related individuals. PLoS One (2013) 0.97
Combining family- and population-based imputation data for association analysis of rare and common variants in large pedigrees. Genet Epidemiol (2014) 0.93
Gastrointestinal stromal tumors, somatic mutations and candidate genetic risk variants. PLoS One (2013) 0.90
A variance component based multi-marker association test using family and unrelated data. BMC Genet (2013) 0.90
Comparing the power of family-based association tests for sequence data with applications in the GAW18 simulated data. BMC Proc (2014) 0.88
A general non-linear multilevel structural equation mixture model. Front Psychol (2014) 0.87
A kernel machine method for detecting effects of interaction between multidimensional variable sets: an imaging genetics application. Neuroimage (2015) 0.86
Collapsing-based and kernel-based single-gene analyses applied to Genetic Analysis Workshop 17 mini-exome data. BMC Proc (2011) 0.85
Testing gene-environment interactions in gene-based association studies. BMC Proc (2011) 0.85
Likelihood Ratio Test for Excess Homozygosity at Marker Loci on X Chromosome. PLoS One (2015) 0.84
Trajectory analyses in alcohol treatment research. Alcohol Clin Exp Res (2012) 0.83
A method for analyzing multiple continuous phenotypes in rare variant association studies allowing for flexible correlations in variant effects. Eur J Hum Genet (2016) 0.81
Flexible and robust methods for rare-variant testing of quantitative traits in trios and nuclear families. Genet Epidemiol (2014) 0.81
Association of polymorphisms in natural killer cell-related genes with preterm birth. Am J Epidemiol (2013) 0.80
A statistical approach for rare-variant association testing in affected sibships. Am J Hum Genet (2015) 0.80
A Sequence Kernel Association Test for Dichotomous Traits in Family Samples under a Generalized Linear Mixed Model. Hum Hered (2015) 0.80
An efficient weighted tag SNP-set analytical method in genome-wide association studies. BMC Genet (2015) 0.79
Assessing gene-environment interactions for common and rare variants with binary traits using gene-trait similarity regression. Genetics (2015) 0.79
Meta-analysis for Discovering Rare-Variant Associations: Statistical Methods and Software Programs. Am J Hum Genet (2015) 0.78
Associating Multivariate Quantitative Phenotypes with Genetic Variants in Family Samples with a Novel Kernel Machine Regression Method. Genetics (2015) 0.78
Permutation-based variance component test in generalized linear mixed model with application to multilocus genetic association study. BMC Med Res Methodol (2015) 0.78
Rare-Variant Kernel Machine Test for Longitudinal Data from Population and Family Samples. Hum Hered (2016) 0.78
A novel random effect model for GWAS meta-analysis and its application to trans-ethnic meta-analysis. Biometrics (2016) 0.78
Incorporating gene-environment interaction in testing for association with rare genetic variants. Hum Hered (2014) 0.78
Random Effects Model for Multiple Pathway Analysis with Applications to Type II Diabetes Microarray Data. Stat Biosci (2014) 0.77
Power analysis of principal components regression in genetic association studies. J Zhejiang Univ Sci B (2009) 0.77
A Fast Multiple-Kernel Method With Applications to Detect Gene-Environment Interaction. Genet Epidemiol (2015) 0.76
A sexually transmitted infection screening algorithm based on semiparametric regression models. Stat Med (2015) 0.75
Kernel-based logistic regression model for protein sequence without vectorialization. Biostatistics (2014) 0.75
Determination of proportionality in two-part models and analysis of Multi-Ethnic Study of Atherosclerosis (MESA). Stat Interface (2011) 0.75
Testing polynomial covariate effects in linear and generalized linear mixed models. Stat Surv (2008) 0.75
A Set-Based Mixed Effect Model for Gene-Environment Interaction and Its Application to Neuroimaging Phenotypes. Front Neurosci (2017) 0.75
Rare-variant association testing for sequencing data with the sequence kernel association test. Am J Hum Genet (2011) 18.88
Quality of life and satisfaction with outcome among prostate-cancer survivors. N Engl J Med (2008) 18.60
LKB1 modulates lung cancer differentiation and metastasis. Nature (2007) 7.80
Powerful SNP-set analysis for case-control genome-wide association studies. Am J Hum Genet (2010) 6.60
Optimal unified approach for rare-variant association testing with application to small-sample case-control whole-exome sequencing studies. Am J Hum Genet (2012) 5.48
A powerful and flexible multilocus association test for quantitative traits. Am J Hum Genet (2008) 4.96
Aberrant lipid metabolism disrupts calcium homeostasis causing liver endoplasmic reticulum stress in obesity. Nature (2011) 4.78
Optimal tests for rare variant effects in sequencing association studies. Biostatistics (2012) 4.69
Semiparametric regression of multidimensional genetic pathway data: least-squares kernel machines and linear mixed models. Biometrics (2007) 4.66
Estimation and testing for the effect of a genetic pathway on a disease outcome using logistic kernel machine regression via logistic mixed models. BMC Bioinformatics (2008) 3.70
Sequence kernel association tests for the combined effect of rare and common variants. Am J Hum Genet (2013) 2.41
Genetic variants on 15q25.1, smoking, and lung cancer: an assessment of mediation and interaction. Am J Epidemiol (2012) 2.16
SNP set association analysis for familial data. Genet Epidemiol (2012) 2.08
Semiparametric modeling of longitudinal measurements and time-to-event data--a two-stage regression calibration approach. Biometrics (2008) 2.05
VEGF polymorphisms and survival in early-stage non-small-cell lung cancer. J Clin Oncol (2008) 1.94
General framework for meta-analysis of rare variants in sequencing association studies. Am J Hum Genet (2013) 1.86
Mixtures of varying coefficient models for longitudinal data with discrete or continuous nonignorable dropout. Biometrics (2004) 1.85
Impact of physician asthma care education on patient outcomes. Pediatrics (2006) 1.70
A comparison of methods for estimating the causal effect of a treatment in randomized clinical trials subject to noncompliance. Biometrics (2008) 1.70
A varying-coefficient Cox model for the effect of age at a marker event on age at menopause. Biometrics (2005) 1.68
Clinical presentation, recurrence, and survival in patients with neuroendocrine tumors: results from a prospective institutional database. Endocr Relat Cancer (2013) 1.62
Family-based association tests for sequence data, and comparisons with population-based association tests. Eur J Hum Genet (2013) 1.55
Genome-wide analysis of survival in early-stage non-small-cell lung cancer. J Clin Oncol (2009) 1.52
A tobit variance-component method for linkage analysis of censored trait data. Am J Hum Genet (2003) 1.49
The effect of correlation in false discovery rate estimation. Biometrika (2011) 1.46
Scaled marginal models for multiple continuous outcomes. Biostatistics (2003) 1.46
Air pollution-associated changes in lung function among asthmatic children in Detroit. Environ Health Perspect (2005) 1.45
Finding disease variants in Mendelian disorders by using sequence data: methods and applications. Am J Hum Genet (2011) 1.40
Detecting rare variant effects using extreme phenotype sampling in sequencing association studies. Genet Epidemiol (2012) 1.35
Ascertainment-adjusted parameter estimates revisited. Am J Hum Genet (2002) 1.34
Genotypes and haplotypes of matrix metalloproteinase 1, 3 and 12 genes and the risk of lung cancer. Carcinogenesis (2005) 1.33
Sparse linear discriminant analysis for simultaneous testing for the significance of a gene set/pathway and gene selection. Bioinformatics (2009) 1.32
Semiparametric Maximum Likelihood Estimation in Normal Transformation Models for Bivariate Survival Data. Biometrika (2008) 1.31
The role of choice in health education intervention trials: a review and case study. Soc Sci Med (2003) 1.30
Kernel machine approach to testing the significance of multiple genetic markers for risk prediction. Biometrics (2011) 1.30
Genome-wide association analysis for multiple continuous secondary phenotypes. Am J Hum Genet (2013) 1.29
Kernel machine SNP-set analysis for censored survival outcomes in genome-wide association studies. Genet Epidemiol (2011) 1.29
Staging reproductive aging: a comparison of proposed bleeding criteria for the menopausal transition. Menopause (2004) 1.27
Progression of subclinical coronary atherosclerosis: does obesity make a difference? Circulation (2005) 1.27
Vascular endothelial growth factor genotypes, haplotypes, gender, and the risk of non-small cell lung cancer. Clin Cancer Res (2008) 1.24
Quantitative quality-assessment techniques to compare fractionation and depletion methods in SELDI-TOF mass spectrometry experiments. Bioinformatics (2007) 1.22
Test for interactions between a genetic marker set and environment in generalized linear models. Biostatistics (2013) 1.20
Exposure to airborne particulate matter is associated with methylation pattern in the asthma pathway. Epigenomics (2013) 1.17
Neuropsychological effects of low-level manganese exposure in welders. Neurotoxicology (2010) 1.16
Apoptosis gene polymorphisms, age, smoking and the risk of non-small cell lung cancer. Carcinogenesis (2008) 1.15
GEE-based SNP set association test for continuous and discrete traits in family-based association studies. Genet Epidemiol (2013) 1.14
Variation in folate pathway genes contributes to risk of congenital heart defects among individuals with Down syndrome. Genet Epidemiol (2010) 1.14
Risk factors for low bone mineral density and the 6-year rate of bone loss among premenopausal and perimenopausal women. Osteoporos Int (2004) 1.13
Toenail, blood, and urine as biomarkers of manganese exposure. J Occup Environ Med (2011) 1.12
A Large-scale genetic association study of esophageal adenocarcinoma risk. Carcinogenesis (2010) 1.12
Evaluation of Viable Dynamic Treatment Regimes in a Sequentially Randomized Trial of Advanced Prostate Cancer. J Am Stat Assoc (2012) 1.11
Sparse principal component analysis for identifying ancestry-informative markers in genome-wide association studies. Genet Epidemiol (2012) 1.10
Two-stage functional mixed models for evaluating the effect of longitudinal covariate profiles on a scalar outcome. Biometrics (2007) 1.09
Missing covariates in longitudinal data with informative dropouts: bias analysis and inference. Biometrics (2005) 1.09
Using eQTL weights to improve power for genome-wide association studies: a genetic study of childhood asthma. Front Genet (2013) 1.08
Increased power for the analysis of label-free LC-MS/MS proteomics data by combining spectral counts and peptide peak attributes. Mol Cell Proteomics (2010) 1.08
Variable selection and estimation in generalized linear models with the seamless L0 penalty. Can J Stat (2012) 1.06
Fetal window of vulnerability to airborne polycyclic aromatic hydrocarbons on proportional intrauterine growth restriction. PLoS One (2012) 1.06
Cigarette smoking increases copy number alterations in nonsmall-cell lung cancer. Proc Natl Acad Sci U S A (2011) 1.05
Identifying genetic marker sets associated with phenotypes via an efficient adaptive score test. Biostatistics (2012) 1.04
Arsenic reduction in drinking water and improvement in skin lesions: a follow-up study in Bangladesh. Environ Health Perspect (2012) 1.03
Interictal epileptiform discharges do not change before seizures during sleep. Epilepsia (2002) 1.03
Prognostic significance of MTOR pathway component expression in neuroendocrine tumors. J Clin Oncol (2013) 1.02
Genetic polymorphisms of VEGF, interactions with cigarette smoking exposure and esophageal adenocarcinoma risk. Carcinogenesis (2008) 1.01
Assessment of occupational exposure to manganese and other metals in welding fumes by portable X-ray fluorescence spectrometer. J Occup Environ Hyg (2010) 1.00
Coronary artery calcification progression is heritable. Circulation (2007) 0.99
Powerful tests for detecting a gene effect in the presence of possible gene-gene interactions using garrote kernel machines. Biometrics (2011) 0.99
Insulin-like growth factor pathway genetic polymorphisms, circulating IGF1 and IGFBP3, and prostate cancer survival. J Natl Cancer Inst (2014) 0.98
Plasma neutrophil elastase and elafin imbalance is associated with acute respiratory distress syndrome (ARDS) development. PLoS One (2009) 0.98
Asking the correct questions to assess asthma symptoms. Clin Pediatr (Phila) (2005) 0.95
Prior biological knowledge-based approaches for the analysis of genome-wide expression profiles using gene sets and pathways. Stat Methods Med Res (2009) 0.94
Estimation in semiparametric transition measurement error models for longitudinal data. Biometrics (2009) 0.94
SEMIPARAMETRIC REGRESSION WITH TIME-DEPENDENT COEFFICIENTS FOR FAILURE TIME DATA ANALYSIS. Stat Sin (2010) 0.93
The effect of patient choice of intervention on health outcomes. Contemp Clin Trials (2008) 0.93
Parental management of asthma triggers within a child's environment. J Allergy Clin Immunol (2004) 0.92
Interactions among genetic variants in apoptosis pathway genes, reflux symptoms, body mass index, and smoking indicate two distinct etiologic patterns of esophageal adenocarcinoma. J Clin Oncol (2010) 0.92
Time-dependent cross ratio estimation for bivariate failure times. Biometrika (2011) 0.92
Spatial Linear Mixed Models with Covariate Measurement Errors. Stat Sin (2009) 0.91
Parity and risk of lung cancer in women. Am J Epidemiol (2010) 0.91
Estimating Causal Effects in Trials Involving Multi-Treatment Arms Subject to Non-compliance: A Bayesian framework. J R Stat Soc Ser C Appl Stat (2010) 0.90
Mediation analysis when a continuous mediator is measured with error and the outcome follows a generalized linear model. Stat Med (2014) 0.89
Epigenome-wide DNA methylation changes with development of arsenic-induced skin lesions in Bangladesh: a case-control follow-up study. Environ Mol Mutagen (2014) 0.89
SEMIPARAMETRIC TRANSFORMATION MODELS WITH RANDOM EFFECTS FOR CLUSTERED FAILURE TIME DATA. Stat Sin (2008) 0.89
Gene set analysis using variance component tests. BMC Bioinformatics (2013) 0.89
Bayesian inference in semiparametric mixed models for longitudinal data. Biometrics (2009) 0.88
Structural inference in transition measurement error models for longitudinal data. Biometrics (2006) 0.88
Nonparametric Regression With Missing Outcomes Using Weighted Kernel Estimating Equations. J Am Stat Assoc (2012) 0.87
Biomarker discovery for arsenic exposure using functional data. Analysis and feature learning of mass spectrometry proteomic data. J Proteome Res (2008) 0.87
Inverse probability of censoring weighted estimates of Kendall's τ for gap time analyses. Biometrics (2010) 0.87
Heart rate variability and DNA methylation levels are altered after short-term metal fume exposure among occupational welders: a repeated-measures panel study. BMC Public Health (2014) 0.87
Design and analysis issues in gene and environment studies. Environ Health (2012) 0.86
A population pharmacokinetic model with time-dependent covariates measured with errors. Biometrics (2004) 0.86
Using canonical correlation analysis to discover genetic regulatory variants. PLoS One (2010) 0.85
Substance use and psychotherapeutic medications: a likely contributor to menstrual disorders in women who are seropositive for human immunodeficiency virus. Am J Obstet Gynecol (2003) 0.85
Association test based on SNP set: logistic kernel machine based test vs. principal component analysis. PLoS One (2012) 0.85
Impact on disease development, genomic location and biological function of copy number alterations in non-small cell lung cancer. PLoS One (2011) 0.85
Air pollution and respiratory symptoms among children with asthma: vulnerability by corticosteroid use and residence area. Sci Total Environ (2012) 0.85
Platelet count mediates the contribution of a genetic variant in LRRC16A to ARDS risk. Chest (2015) 0.83
Short-term airborne particulate matter exposure alters the epigenetic landscape of human genes associated with the mitogen-activated protein kinase network: a cross-sectional study. Environ Health (2014) 0.83