Published in Curr Opin Biotechnol on August 01, 2003
Development of a high-throughput screen for soluble epoxide hydrolase inhibition. Anal Biochem (2006) 1.19
The X-ray structure of the haloalcohol dehalogenase HheA from Arthrobacter sp. strain AD2: insight into enantioselectivity and halide binding in the haloalcohol dehalogenase family. J Bacteriol (2006) 0.86
A broadly applicable and practical oligomeric (salen) Co catalyst for enantioselective epoxide ring-opening reactions. Tetrahedron (2014) 0.86
One-pot deracemization of sec-alcohols: enantioconvergent enzymatic hydrolysis of alkyl sulfates using stereocomplementary sulfatases. Angew Chem Int Ed Engl (2013) 0.81
Oxidative Cyclization in Natural Product Biosynthesis. Chem Rev (2016) 0.81
One-Pot Deracemization of sec-Alcohols: Enantioconvergent Enzymatic Hydrolysis of Alkyl Sulfates Using Stereocomplementary Sulfatases. Angew Chem Weinheim Bergstr Ger (2013) 0.78
Compositional profile of α / β-hydrolase fold proteins in mangrove soil metagenomes: prevalence of epoxide hydrolases and haloalkane dehalogenases in oil-contaminated sites. Microb Biotechnol (2014) 0.77
Engineering of an epoxide hydrolase for efficient bioresolution of bulky pharmaco substrates. Proc Natl Acad Sci U S A (2014) 0.76
Enhancing the biocatalytic manufacture of the key intermediate of atorvastatin by focused directed evolution of halohydrin dehalogenase. Sci Rep (2017) 0.75
Synthesis and evaluation of phenylalanine-derived trifluoromethyl ketones for peptide-based oxidation catalysis. Bioorg Med Chem (2016) 0.75
Enzyme-catalyzed cationic epoxide rearrangements in quinolone alkaloid biosynthesis. Nat Chem Biol (2017) 0.75
Production of epoxide hydrolases in batch fermentations of Botryosphaeria rhodina. J Ind Microbiol Biotechnol (2008) 0.75
Identification of a Baeyer-Villiger monooxygenase sequence motif. FEBS Lett (2002) 1.68
Discovery of a thermostable Baeyer-Villiger monooxygenase by genome mining. Appl Microbiol Biotechnol (2004) 1.46
Quantifying the accessibility of the metagenome by random expression cloning techniques. Environ Microbiol (2004) 1.43
Rhamnolipid stimulates uptake of hydrophobic compounds by Pseudomonas aeruginosa. Appl Environ Microbiol (2002) 1.41
Recent advances in the catalytic asymmetric synthesis of beta-amino acids. Chem Soc Rev (2010) 1.35
Efficient recovery of environmental DNA for expression cloning by indirect extraction methods. FEMS Microbiol Ecol (2003) 1.25
Biodegradation of 1,2,3-trichloropropane through directed evolution and heterologous expression of a haloalkane dehalogenase gene. Appl Environ Microbiol (2002) 1.25
The prodrug activator EtaA from Mycobacterium tuberculosis is a Baeyer-Villiger monooxygenase. J Biol Chem (2003) 1.25
Kinetic mechanism of phenylacetone monooxygenase from Thermobifida fusca. Biochemistry (2008) 1.18
Substrate specificity and enantioselectivity of 4-hydroxyacetophenone monooxygenase. Appl Environ Microbiol (2003) 1.17
Directed evolution of epoxide hydrolase from A. radiobacter toward higher enantioselectivity by error-prone PCR and DNA shuffling. Chem Biol (2004) 1.08
Elucidation of the 4-hydroxyacetophenone catabolic pathway in Pseudomonas fluorescens ACB. J Bacteriol (2008) 1.05
The sequence and crystal structure of the alpha-amino acid ester hydrolase from Xanthomonas citri define a new family of beta-lactam antibiotic acylases. J Biol Chem (2003) 1.04
Identifying determinants of NADPH specificity in Baeyer-Villiger monooxygenases. Eur J Biochem (2004) 1.03
Molecular dynamics simulations as a tool for improving protein stability. Protein Eng (2002) 0.99
Phenylalanine aminomutase-catalyzed addition of ammonia to substituted cinnamic acids: a route to enantiopure alpha- and beta-amino acids. J Org Chem (2009) 0.99
Structure- and sequence-analysis inspired engineering of proteins for enhanced thermostability. Curr Opin Struct Biol (2013) 0.99
Priming ammonia lyases and aminomutases for industrial and therapeutic applications. Curr Opin Chem Biol (2013) 0.99
Discovery, characterization, and kinetic analysis of an alditol oxidase from Streptomyces coelicolor. J Biol Chem (2007) 0.99
Catalytic mechanism of the maloalkane dehalogenase LinB from Sphingomonas paucimobilis UT26. J Biol Chem (2003) 0.98
Enantioselectivity of haloalkane dehalogenases and its modulation by surface loop engineering. Angew Chem Int Ed Engl (2010) 0.98
Discovery of a novel styrene monooxygenase originating from the metagenome. Appl Environ Microbiol (2007) 0.96
Diversity and biocatalytic potential of epoxide hydrolases identified by genome analysis. Appl Environ Microbiol (2006) 0.95
Construction, characterization, and use of small-insert gene banks of DNA isolated from soil and enrichment cultures for the recovery of novel amidases. Environ Microbiol (2004) 0.94
Characterization of a phenylacetate-CoA ligase from Penicillium chrysogenum. Biochem J (2009) 0.94
Acetobacter turbidans alpha-amino acid ester hydrolase: how a single mutation improves an antibiotic-producing enzyme. J Biol Chem (2005) 0.93
Identification of the catalytic residues of alpha-amino acid ester hydrolase from Acetobacter turbidans by labeling and site-directed mutagenesis. J Biol Chem (2002) 0.93
Biodegradation kinetics of 4-fluorocinnamic acid by a consortium of Arthrobacter and Ralstonia strains. Biodegradation (2011) 0.93
The enhancement by surfactants of hexadecane degradation by Pseudomonas aeruginosa varies with substrate availability. J Biotechnol (2002) 0.93
Computationally designed libraries for rapid enzyme stabilization. Protein Eng Des Sel (2014) 0.92
Kinetic mechanism and enantioselectivity of halohydrin dehalogenase from Agrobacterium radiobacter. Biochemistry (2003) 0.91
Steady-state kinetics and tryptophan fluorescence properties of halohydrin dehalogenase from Agrobacterium radiobacter. Roles of W139 and W249 in the active site and halide-induced conformational change. Biochemistry (2003) 0.91
Generating segmental mutations in haloalkane dehalogenase: a novel part in the directed evolution toolbox. Nucleic Acids Res (2002) 0.91
Alteration of the diastereoselectivity of 3-methylaspartate ammonia lyase by using structure-based mutagenesis. Chembiochem (2009) 0.90
The role of hydrophobic active-site residues in substrate specificity and acyl transfer activity of penicillin acylase. Eur J Biochem (2002) 0.90
Discovery and characterization of a putrescine oxidase from Rhodococcus erythropolis NCIMB 11540. Appl Microbiol Biotechnol (2008) 0.89
Coenzyme binding during catalysis is beneficial for the stability of 4-hydroxyacetophenone monooxygenase. J Biol Chem (2005) 0.89
Discovery of a eugenol oxidase from Rhodococcus sp. strain RHA1. FEBS J (2007) 0.89
Catalytic promiscuity of halohydrin dehalogenase and its application in enantioselective epoxide ring opening. Chembiochem (2008) 0.88
Role of alphaArg145 and betaArg263 in the active site of penicillin acylase of Escherichia coli. Biochem J (2002) 0.88
Characterization of cytochrome P450 monooxygenase CYP154H1 from the thermophilic soil bacterium Thermobifida fusca. Appl Microbiol Biotechnol (2010) 0.88
The role of double covalent flavin binding in chito-oligosaccharide oxidase from Fusarium graminearum. Biochem J (2008) 0.88
Improved catalytic properties of halohydrin dehalogenase by modification of the halide-binding site. Biochemistry (2005) 0.88
Covalent flavinylation of vanillyl-alcohol oxidase is an autocatalytic process. FEBS J (2008) 0.86
Biocatalytic enantioselective synthesis of N-substituted aspartic acids by aspartate ammonia lyase. Chemistry (2008) 0.86
Enantioselective enzymes by computational design and in silico screening. Angew Chem Int Ed Engl (2015) 0.86
The X-ray structure of the haloalcohol dehalogenase HheA from Arthrobacter sp. strain AD2: insight into enantioselectivity and halide binding in the haloalcohol dehalogenase family. J Bacteriol (2006) 0.86
Increasing the synthetic performance of penicillin acylase PAS2 by structure-inspired semi-random mutagenesis. Protein Eng Des Sel (2004) 0.86
Engineering methylaspartate ammonia lyase for the asymmetric synthesis of unnatural amino acids. Nat Chem (2012) 0.86
Computational design gains momentum in enzyme catalysis engineering. FEBS J (2013) 0.86
Directed evolution strategies for enantiocomplementary haloalkane dehalogenases: from chemical waste to enantiopure building blocks. Chembiochem (2011) 0.86
Degradation of 4-fluorophenol by Arthrobacter sp. strain IF1. Appl Microbiol Biotechnol (2008) 0.85
Structural basis for the enantioselectivity of an epoxide ring opening reaction catalyzed by halo alcohol dehalogenase HheC. J Am Chem Soc (2005) 0.84
Kinetics of enzyme acylation and deacylation in the penicillin acylase-catalyzed synthesis of beta-lactam antibiotics. Eur J Biochem (2003) 0.84
Changing the substrate specificity of a chitooligosaccharide oxidase from Fusarium graminearum by model-inspired site-directed mutagenesis. FEBS Lett (2007) 0.84
Azobenzene photoswitches for Staudinger-Bertozzi ligation. Angew Chem Int Ed Engl (2013) 0.83
A simple enantioconvergent and chemoenzymatic synthesis of optically active α-substituted amides. Angew Chem Int Ed Engl (2011) 0.83
Steady-state and pre-steady-state kinetic analysis of halopropane conversion by a rhodococcus haloalkane dehalogenase. Biochemistry (2003) 0.83
Dynamic kinetic resolution of racemic beta-haloalcohols: direct access to enantioenriched epoxides. J Am Chem Soc (2008) 0.83
Synthesis of enantiopure chloroalcohols by enzymatic kinetic resolution. Org Biomol Chem (2006) 0.83
The Penicillium chrysogenum aclA gene encodes a broad-substrate-specificity acyl-coenzyme A ligase involved in activation of adipic acid, a side-chain precursor for cephem antibiotics. Fungal Genet Biol (2010) 0.83
Mechanism-inspired engineering of phenylalanine aminomutase for enhanced β-regioselective asymmetric amination of cinnamates. Angew Chem Int Ed Engl (2011) 0.83
Degradation of chloroaromatics by Pseudomonas putida GJ31: assembled route for chlorobenzene degradation encoded by clusters on plasmid pKW1 and the chromosome. Microbiology (2009) 0.83
Aminomutases: mechanistic diversity, biotechnological applications and future perspectives. Trends Biotechnol (2011) 0.82
Enzymatic synthesis of enantiopure alpha- and beta-amino acids by phenylalanine aminomutase-catalysed amination of cinnamic acid derivatives. Chembiochem (2009) 0.82
Kinetic resolution and stereoselective synthesis of 3-substituted aspartic acids by using engineered methylaspartate ammonia lyases. Chemistry (2013) 0.82
Characterization of a thermostable methylaspartate ammonia lyase from Carboxydothermus hydrogenoformans. Appl Microbiol Biotechnol (2011) 0.81
Cloning, sequence analysis, and expression in Escherichia coli of the gene encoding an alpha-amino acid ester hydrolase from Acetobacter turbidans. Appl Environ Microbiol (2002) 0.81
Saturation mutagenesis reveals the importance of residues alphaR145 and alphaF146 of penicillin acylase in the synthesis of beta-lactam antibiotics. J Biotechnol (2007) 0.81
Degradation of fluorobenzene by Rhizobiales strain F11 via ortho cleavage of 4-fluorocatechol and catechol. Appl Environ Microbiol (2006) 0.80
Biocatalytic and structural properties of a highly engineered halohydrin dehalogenase. Chembiochem (2013) 0.80
Structural and kinetic studies on ligand binding in wild-type and active-site mutants of penicillin acylase. Protein Eng Des Sel (2004) 0.80
Enantiomerically pure beta-phenylalanine analogues from alpha-beta-phenylalanine mixtures in a single reactive extraction step. Chem Commun (Camb) (2009) 0.79
Formation of enantiopure 5-substituted oxazolidinones through enzyme-catalysed kinetic resolution of epoxides. Org Lett (2008) 0.79
One pot 'click' reactions: tandem enantioselective biocatalytic epoxide ring opening and [3+2] azide alkyne cycloaddition. Chem Commun (Camb) (2010) 0.79
Selective steroid oxyfunctionalisation by CYP154C5, a bacterial cytochrome P450. Microb Cell Fact (2013) 0.79
Sequential kinetic resolution catalyzed by halohydrin dehalogenase. Org Lett (2006) 0.79
Export of functional Streptomyces coelicolor alditol oxidase to the periplasm or cell surface of Escherichia coli and its application in whole-cell biocatalysis. Appl Microbiol Biotechnol (2009) 0.79
Isolation and characterization of a Rhodococcus strain able to degrade 2-fluorophenol. Appl Microbiol Biotechnol (2011) 0.79
Engineering of an enantioselective tyrosine aminomutase by mutation of a single active site residue in phenylalanine aminomutase. Chem Commun (Camb) (2010) 0.78
Complete biodegradation of 4-fluorocinnamic acid by a consortium comprising Arthrobacter sp. strain G1 and Ralstonia sp. strain H1. Appl Environ Microbiol (2010) 0.78
Site-directed mutagenesis, kinetic and inhibition studies of aspartate ammonia lyase from Bacillus sp. YM55-1. FEBS J (2009) 0.78
Biochemical properties and crystal structure of a β-phenylalanine aminotransferase from Variovorax paradoxus. Appl Environ Microbiol (2012) 0.77
Novel dehalogenase mechanism for 2,3-dichloro-1-propanol utilization in Pseudomonas putida strain MC4. Appl Environ Microbiol (2012) 0.77
Computational library design for increasing haloalkane dehalogenase stability. Chembiochem (2014) 0.77
Computationally efficient and accurate enantioselectivity modeling by clusters of molecular dynamics simulations. J Chem Inf Model (2014) 0.77
Metabolism of mono- and dihalogenated C1 and C2 compounds by Xanthobacter autotrophicus growing on 1,2-dichloroethane. Biodegradation (2006) 0.77
Structural investigations into the stereochemistry and activity of a phenylalanine-2,3-aminomutase from Taxus chinensis. Biochemistry (2014) 0.76
Crystallization and preliminary X-ray analysis of an enantioselective halohydrin dehalogenase from Agrobacterium radiobacter AD1. Acta Crystallogr D Biol Crystallogr (2001) 0.76
Transformation and biodegradation of 1,2,3-trichloropropane (TCP). Environ Sci Pollut Res Int (2012) 0.76
Analysis of two gene clusters involved in the degradation of 4-fluorophenol by Arthrobacter sp. strain IF1. Appl Environ Microbiol (2009) 0.76
Structural determinants of the β-selectivity of a bacterial aminotransferase. J Biol Chem (2012) 0.76
Merging homogeneous catalysis with biocatalysis; papain as hydrogenation catalyst. Chem Commun (Camb) (2005) 0.75
Proteolysin, a novel highly thermostable and cosolvent-compatible protease from the thermophilic bacterium Coprothermobacter proteolyticus. Appl Environ Microbiol (2013) 0.75
ADP competes with FAD binding in putrescine oxidase. J Biol Chem (2008) 0.75
Functional Exchangeability of Oxidase and Dehydrogenase Reactions in the Biosynthesis of Hydroxyphenylglycine, a Nonribosomal Peptide Building Block. ACS Synth Biol (2015) 0.75
Aminoacyl-coenzyme A synthesis catalyzed by a CoA ligase from Penicillium chrysogenum. FEBS Lett (2011) 0.75
Inactivation of epoxide hydrolase by catalysis-induced formation of isoaspartate. FEBS Lett (2008) 0.75
Degradation of chloroaromatics: structure and catalytic activities of wild-type chlorocatechol 2,3-dioxygenases and modified ones. Environ Microbiol (2012) 0.75
Purification and use of E. coli peptide deformylase for peptide deprotection in chemoenzymatic peptide synthesis. Protein Expr Purif (2013) 0.75