Enzyme-catalyzed cationic epoxide rearrangements in quinolone alkaloid biosynthesis.

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Published in Nat Chem Biol on January 23, 2017

Authors

Yi Zou1, Marc Garcia-Borràs2, Mancheng C Tang1, Yuichiro Hirayama3, Dehai H Li4, Li Li1, Kenji Watanabe3, K N Houk5, Yi Tang1,5

Author Affiliations

1: Department of Chemical and Biomolecular Engineering, University of California, Los Angeles, Los Angeles, California, USA.
2: Institut de Química Computacional i Catàlisi (IQCC), Departament de Química, Universitat de Girona, Campus Montilivi, 17071, Girona, Catalonia, Spain.
3: Department of Pharmaceutical Sciences, University of Shizuoka, Shizuoka, Japan.
4: Key Laboratory of Marine Drugs, Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qingdao, China.
5: Department of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, California, USA.

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