Dissociating valence of outcome from behavioral control in human orbital and ventral prefrontal cortices.

PubWeight™: 4.21‹?› | Rank: Top 1%

🔗 View Article (PMID 12944524)

Published in J Neurosci on August 27, 2003

Authors

John O'Doherty1, Hugo Critchley, Ralf Deichmann, Raymond J Dolan

Author Affiliations

1: Wellcome Department of Imaging Neuroscience, Institute of Neurology, London WC1N 3BG, United Kingdom. j.odoherty@fil.ion.ucl.ac.uk

Articles citing this

(truncated to the top 100)

The reward circuit: linking primate anatomy and human imaging. Neuropsychopharmacology (2010) 10.17

The neural correlates of subjective value during intertemporal choice. Nat Neurosci (2007) 9.46

Is avoiding an aversive outcome rewarding? Neural substrates of avoidance learning in the human brain. PLoS Biol (2006) 3.80

Triadic model of the neurobiology of motivated behavior in adolescence. Psychol Med (2006) 3.62

Encoding of time-discounted rewards in orbitofrontal cortex is independent of value representation. Neuron (2006) 3.45

Separable learning systems in the macaque brain and the role of orbitofrontal cortex in contingent learning. Neuron (2010) 3.28

Common and distinct networks underlying reward valence and processing stages: a meta-analysis of functional neuroimaging studies. Neurosci Biobehav Rev (2010) 2.94

Differential effects of insular and ventromedial prefrontal cortex lesions on risky decision-making. Brain (2008) 2.82

Shifting and stopping: fronto-striatal substrates, neurochemical modulation and clinical implications. Philos Trans R Soc Lond B Biol Sci (2007) 2.66

Neural evidence for inequality-averse social preferences. Nature (2010) 2.64

From fear to safety and back: reversal of fear in the human brain. J Neurosci (2008) 2.63

Dissociable neural representations of future reward magnitude and delay during temporal discounting. Neuroimage (2008) 2.52

Neural substrates of choice selection in adults and adolescents: development of the ventrolateral prefrontal and anterior cingulate cortices. Neuropsychologia (2006) 2.44

Determining a role for ventromedial prefrontal cortex in encoding action-based value signals during reward-related decision making. Cereb Cortex (2008) 2.40

Decoding the neural substrates of reward-related decision making with functional MRI. Proc Natl Acad Sci U S A (2007) 2.26

Automatic independent component labeling for artifact removal in fMRI. Neuroimage (2007) 2.24

Double dissociation of the effects of medial and orbital prefrontal cortical lesions on attentional and affective shifts in mice. J Neurosci (2008) 2.22

Hierarchically organized behavior and its neural foundations: a reinforcement learning perspective. Cognition (2008) 2.18

Abnormal ventromedial prefrontal cortex function in children with psychopathic traits during reversal learning. Arch Gen Psychiatry (2008) 2.06

The social-emotional processing stream: five core constructs and their translational potential for schizophrenia and beyond. Biol Psychiatry (2008) 2.02

Goal representations and motivational drive in schizophrenia: the role of prefrontal-striatal interactions. Schizophr Bull (2010) 2.01

Neural computations underlying action-based decision making in the human brain. Proc Natl Acad Sci U S A (2009) 1.98

A developmental neurobiological model of motivated behavior: anatomy, connectivity and ontogeny of the triadic nodes. Neurosci Biobehav Rev (2008) 1.95

Obsessive-compulsive disorder: beyond segregated cortico-striatal pathways. Trends Cogn Sci (2011) 1.94

What we know and do not know about the functions of the orbitofrontal cortex after 20 years of cross-species studies. J Neurosci (2007) 1.93

Social network modulation of reward-related signals. J Neurosci (2012) 1.84

Retracted Motivated cognitive control: reward incentives modulate preparatory neural activity during task-switching. J Neurosci (2010) 1.82

Functional dissociations of risk and reward processing in the medial prefrontal cortex. Cereb Cortex (2008) 1.78

Rules ventral prefrontal cortical axons use to reach their targets: implications for diffusion tensor imaging tractography and deep brain stimulation for psychiatric illness. J Neurosci (2011) 1.76

Neural correlates of individual differences in pain-related fear and anxiety. Pain (2005) 1.76

Are attractive people rewarding? Sex differences in the neural substrates of facial attractiveness. J Cogn Neurosci (2008) 1.64

Insight into the relationship between impulsivity and substance abuse from studies using animal models. Alcohol Clin Exp Res (2010) 1.62

Behavioral and neural changes after gains and losses of conditioned reinforcers. J Neurosci (2009) 1.62

The amygdala and ventromedial prefrontal cortex: functional contributions and dysfunction in psychopathy. Philos Trans R Soc Lond B Biol Sci (2008) 1.61

Abnormal frontal activations related to decision-making in current and former amphetamine and opiate dependent individuals. Psychopharmacology (Berl) (2005) 1.61

Ventral striatum response during reward and punishment reversal learning in unmedicated major depressive disorder. Am J Psychiatry (2012) 1.55

The human amygdala and orbital prefrontal cortex in behavioural regulation. Philos Trans R Soc Lond B Biol Sci (2007) 1.52

Perceived control influences neural responses to setbacks and promotes persistence. Neuron (2014) 1.52

Cortical midline involvement in autobiographical memory. Neuroimage (2008) 1.45

Relationship between the corticostriatal terminals from areas 9 and 46, and those from area 8A, dorsal and rostral premotor cortex and area 24c: an anatomical substrate for cognition to action. Eur J Neurosci (2007) 1.43

Your pain or mine? Common and distinct neural systems supporting the perception of pain in self and other. Soc Cogn Affect Neurosci (2008) 1.42

Which way was I going? Contextual retrieval supports the disambiguation of well learned overlapping navigational routes. J Neurosci (2010) 1.37

Neural basis of abnormal response to negative feedback in unmedicated mood disorders. Neuroimage (2008) 1.37

Adaptive decision making and value in the anterior cingulate cortex. Neuroimage (2007) 1.36

Neural components underlying behavioral flexibility in human reversal learning. Cereb Cortex (2009) 1.35

Parkinson's disease and dopaminergic therapy--differential effects on movement, reward and cognition. Brain (2008) 1.29

Preparatory allocation of attention and adjustments in conflict processing. Neuroimage (2007) 1.27

Both Risk and Reward are Processed Differently in Decisions Made Under Stress. Curr Dir Psychol Sci (2012) 1.27

Altered function and connectivity of the medial frontal cortex in pediatric obsessive-compulsive disorder. Biol Psychiatry (2010) 1.26

Differential contributions of the primate ventrolateral prefrontal and orbitofrontal cortex to serial reversal learning. J Neurosci (2010) 1.26

Policy adjustment in a dynamic economic game. PLoS One (2006) 1.24

Dissociable regulation of instrumental action within mouse prefrontal cortex. Eur J Neurosci (2010) 1.19

Cognitive and motivational deficits together with prefrontal oxidative stress in a mouse model for neuropsychiatric illness. Proc Natl Acad Sci U S A (2013) 1.18

Selective aspiration or neurotoxic lesions of orbital frontal areas 11 and 13 spared monkeys' performance on the object discrimination reversal task. J Neurosci (2009) 1.17

Short-term temporal discounting of reward value in human ventral striatum. J Neurophysiol (2009) 1.16

Neural correlates of instrumental contingency learning: differential effects of action-reward conjunction and disjunction. J Neurosci (2011) 1.16

Pavlovian reward prediction and receipt in schizophrenia: relationship to anhedonia. PLoS One (2012) 1.16

Hyperactive error responses and altered connectivity in ventromedial and frontoinsular cortices in obsessive-compulsive disorder. Biol Psychiatry (2010) 1.16

Event-related potential studies of outcome processing and feedback-guided learning. Front Hum Neurosci (2012) 1.15

An fMRI study of obesity, food reward, and perceived caloric density. Does a low-fat label make food less appealing? Appetite (2011) 1.15

Primary and secondary rewards differentially modulate neural activity dynamics during working memory. PLoS One (2010) 1.15

Brain mechanisms of persuasion: how 'expert power' modulates memory and attitudes. Soc Cogn Affect Neurosci (2008) 1.13

The development of the ventral prefrontal cortex and social flexibility. Dev Cogn Neurosci (2011) 1.13

The inherent reward of choice. Psychol Sci (2011) 1.13

Should I stay or should I go? Transformation of time-discounted rewards in orbitofrontal cortex and associated brain circuits. Ann N Y Acad Sci (2007) 1.12

Developmental stages and sex differences of white matter and behavioral development through adolescence: a longitudinal diffusion tensor imaging (DTI) study. Neuroimage (2013) 1.11

Response options and expectations of reward in decision-making: the differential roles of dorsal and rostral anterior cingulate cortex. Neuroimage (2007) 1.10

Neural coding of reward magnitude in the orbitofrontal cortex of the rat during a five-odor olfactory discrimination task. Learn Mem (2007) 1.10

Social manipulation of preference in the human brain. Neuron (2013) 1.10

Orbitofrontal inactivation impairs reversal of Pavlovian learning by interfering with 'disinhibition' of responding for previously unrewarded cues. Eur J Neurosci (2009) 1.10

Shared brain activity for aesthetic and moral judgments: implications for the Beauty-is-Good stereotype. Soc Cogn Affect Neurosci (2010) 1.09

The medial prefrontal and orbitofrontal cortices differentially regulate dopamine system function. Neuropsychopharmacology (2011) 1.08

CNTRICS final task selection: long-term memory. Schizophr Bull (2008) 1.06

Individual differences in risk preference predict neural responses during financial decision-making. Brain Res (2009) 1.05

The interference of operant task performance by emotional distracters: an antagonistic relationship between the amygdala and frontoparietal cortices. Neuroimage (2007) 1.04

Your resting brain CAREs about your risky behavior. PLoS One (2010) 1.03

Blocking central opiate function modulates hedonic impact and anterior cingulate response to rewards and losses. J Neurosci (2008) 1.03

Interactivity and reward-related neural activation during a serious videogame. PLoS One (2012) 1.02

The neural substrate of prior information in perceptual decision making: a model-based analysis. Front Hum Neurosci (2010) 1.01

Uncertainty and cognitive control. Front Psychol (2011) 1.01

Dissociable responses to punishment in distinct striatal regions during reversal learning. Neuroimage (2010) 1.00

The influence of feedback valence in associative learning. Neuroimage (2008) 1.00

Adapting to dynamic stimulus-response values: differential contributions of inferior frontal, dorsomedial, and dorsolateral regions of prefrontal cortex to decision making. J Neurosci (2009) 1.00

The problem with value. Neurosci Biobehav Rev (2014) 0.99

Reduced behavioral flexibility in autism spectrum disorders. Neuropsychology (2013) 0.98

Inefficiency in self-organized attentional switching in the normal aging population is associated with decreased activity in the ventrolateral prefrontal cortex. J Cogn Neurosci (2008) 0.98

Influence of contingency awareness on neural, electrodermal and evaluative responses during fear conditioning. Soc Cogn Affect Neurosci (2010) 0.97

Selective prefrontal serotonin depletion impairs acquisition of a detour-reaching task. Eur J Neurosci (2006) 0.96

Human reversal learning under conditions of certain versus uncertain outcomes. Neuroimage (2011) 0.96

Mediodorsal thalamus hypofunction impairs flexible goal-directed behavior. Biol Psychiatry (2014) 0.96

Neuroimaging of aggressive and violent behaviour in children and adolescents. Front Behav Neurosci (2009) 0.96

Frontal cortex activation causes rapid plasticity of auditory cortical processing. J Neurosci (2013) 0.95

A mixture of delta-rules approximation to bayesian inference in change-point problems. PLoS Comput Biol (2013) 0.95

Neural circuitry of emotional and cognitive conflict revealed through facial expressions. PLoS One (2011) 0.94

Dissociable roles of medial orbitofrontal cortex in human operant extinction learning. Neuroimage (2008) 0.94

Sex-related differences in neural activity during risk taking: an fMRI study. Cereb Cortex (2008) 0.93

Age-related differences in neural activities during risk taking as revealed by functional MRI. Soc Cogn Affect Neurosci (2007) 0.93

Emotional and autonomic consequences of spinal cord injury explored using functional brain imaging. Brain (2005) 0.93

Effect of reinforcement history on hand choice in an unconstrained reaching task. Front Neurosci (2011) 0.92

Neural correlates of attitude change following positive and negative advertisements. Front Behav Neurosci (2009) 0.92

Articles by these authors

Neural systems supporting interoceptive awareness. Nat Neurosci (2004) 11.88

Dissociable roles of ventral and dorsal striatum in instrumental conditioning. Science (2004) 11.67

Empathy for pain involves the affective but not sensory components of pain. Science (2004) 11.33

Cortical substrates for exploratory decisions in humans. Nature (2006) 10.73

Temporal difference models and reward-related learning in the human brain. Neuron (2003) 8.50

Dopamine-dependent prediction errors underpin reward-seeking behaviour in humans. Nature (2006) 6.90

Encoding predictive reward value in human amygdala and orbitofrontal cortex. Science (2003) 6.76

Frames, biases, and rational decision-making in the human brain. Science (2006) 6.67

Neural responses during anticipation of a primary taste reward. Neuron (2002) 6.40

Empathic neural responses are modulated by the perceived fairness of others. Nature (2006) 6.04

Human cingulate cortex and autonomic control: converging neuroimaging and clinical evidence. Brain (2003) 5.48

Temporal difference models describe higher-order learning in humans. Nature (2004) 4.94

Distant influences of amygdala lesion on visual cortical activation during emotional face processing. Nat Neurosci (2004) 4.72

Image distortion correction in fMRI: A quantitative evaluation. Neuroimage (2002) 4.64

Model-based influences on humans' choices and striatal prediction errors. Neuron (2011) 4.58

Regret and its avoidance: a neuroimaging study of choice behavior. Nat Neurosci (2005) 3.99

Distinct spatial frequency sensitivities for processing faces and emotional expressions. Nat Neurosci (2003) 3.90

When fear is near: threat imminence elicits prefrontal-periaqueductal gray shifts in humans. Science (2007) 3.78

Relating introspective accuracy to individual differences in brain structure. Science (2010) 3.68

Concurrent TMS-fMRI and psychophysics reveal frontal influences on human retinotopic visual cortex. Curr Biol (2006) 3.54

Reward value coding distinct from risk attitude-related uncertainty coding in human reward systems. J Neurophysiol (2006) 3.53

Evidence for segregated and integrative connectivity patterns in the human Basal Ganglia. J Neurosci (2008) 3.43

Context-dependent human extinction memory is mediated by a ventromedial prefrontal and hippocampal network. J Neurosci (2006) 3.17

Morphing Marilyn into Maggie dissociates physical and identity face representations in the brain. Nat Neurosci (2004) 3.12

Optimal EPI parameters for reduction of susceptibility-induced BOLD sensitivity losses: a whole-brain analysis at 3 T and 1.5 T. Neuroimage (2006) 3.00

Predictive neural coding of reward preference involves dissociable responses in human ventral midbrain and ventral striatum. Neuron (2006) 2.72

Appetitive and aversive olfactory learning in humans studied using event-related functional magnetic resonance imaging. J Neurosci (2002) 2.65

Brain responses to the acquired moral status of faces. Neuron (2004) 2.61

Subliminal instrumental conditioning demonstrated in the human brain. Neuron (2008) 2.55

The role of human orbitofrontal cortex in value comparison for incommensurable objects. J Neurosci (2009) 2.51

Brain activity underlying encoding and retrieval of source memory. Cereb Cortex (2002) 2.48

Anterior cingulate activity during error and autonomic response. Neuroimage (2005) 2.47

Oxytocin attenuates affective evaluations of conditioned faces and amygdala activity. J Neurosci (2008) 2.41

Computational psychiatry. Trends Cogn Sci (2011) 2.40

The neural basis of mood-congruent processing biases in depression. Arch Gen Psychiatry (2002) 2.35

Anxiety reduction through detachment: subjective, physiological, and neural effects. J Cogn Neurosci (2005) 2.32

Eye-specific effects of binocular rivalry in the human lateral geniculate nucleus. Nature (2005) 2.30

Neural correlates of value, risk, and risk aversion contributing to decision making under risk. J Neurosci (2009) 2.29

Human orbitofrontal cortex mediates extinction learning while accessing conditioned representations of value. Nat Neurosci (2004) 2.25

Fear conditioning in humans: the influence of awareness and autonomic arousal on functional neuroanatomy. Neuron (2002) 2.22

An agent independent axis for executed and modeled choice in medial prefrontal cortex. Neuron (2012) 2.21

Attentional load and sensory competition in human vision: modulation of fMRI responses by load at fixation during task-irrelevant stimulation in the peripheral visual field. Cereb Cortex (2004) 2.19

Neural mechanisms of belief inference during cooperative games. J Neurosci (2010) 2.18

How humans integrate the prospects of pain and reward during choice. J Neurosci (2009) 2.14

How choice reveals and shapes expected hedonic outcome. J Neurosci (2009) 2.12

Brain systems for assessing facial attractiveness. Neuropsychologia (2006) 2.09

Mapping value based planning and extensively trained choice in the human brain. Nat Neurosci (2012) 2.09

Threatening a rubber hand that you feel is yours elicits a cortical anxiety response. Proc Natl Acad Sci U S A (2007) 2.08

Encoding of emotional memories depends on amygdala and hippocampus and their interactions. Nat Neurosci (2004) 2.08

Distinct causal influences of parietal versus frontal areas on human visual cortex: evidence from concurrent TMS-fMRI. Cereb Cortex (2007) 2.07

Human pavlovian-instrumental transfer. J Neurosci (2008) 2.06

Task and content modulate amygdala-hippocampal connectivity in emotional retrieval. Neuron (2006) 2.05

Real-time functional magnetic resonance imaging: methods and applications. Magn Reson Imaging (2007) 2.01

Confidence in value-based choice. Nat Neurosci (2012) 2.00

Dopamine restores reward prediction errors in old age. Nat Neurosci (2013) 2.00

The neural basis of metacognitive ability. Philos Trans R Soc Lond B Biol Sci (2012) 1.99

Remembrance of odors past: human olfactory cortex in cross-modal recognition memory. Neuron (2004) 1.97

How the opinion of others affects our valuation of objects. Curr Biol (2010) 1.94

How unrealistic optimism is maintained in the face of reality. Nat Neurosci (2011) 1.94

From threat to fear: the neural organization of defensive fear systems in humans. J Neurosci (2009) 1.94

Striatal activity underlies novelty-based choice in humans. Neuron (2008) 1.92

Time-series analysis for rapid event-related skin conductance responses. J Neurosci Methods (2009) 1.87

Genetic association and brain morphology studies and the chromosome 8p22 pericentriolar material 1 (PCM1) gene in susceptibility to schizophrenia. Arch Gen Psychiatry (2006) 1.86

Non-invasive mapping of corticofugal fibres from multiple motor areas--relevance to stroke recovery. Brain (2006) 1.85

Mechanisms underlying dopamine-mediated reward bias in compulsive behaviors. Neuron (2010) 1.85

Information theory, novelty and hippocampal responses: unpredicted or unpredictable? Neural Netw (2005) 1.82

Neural correlates of self-distraction from anxiety and a process model of cognitive emotion regulation. J Cogn Neurosci (2006) 1.82

Voxel-based cortical thickness measurements in MRI. Neuroimage (2008) 1.82

Brain, emotion and decision making: the paradigmatic example of regret. Trends Cogn Sci (2007) 1.77

The cutaneous rabbit illusion affects human primary sensory cortex somatotopically. PLoS Biol (2006) 1.76

Interaction of activation-repolarization coupling and restitution properties in humans. Circ Arrhythm Electrophysiol (2009) 1.75

Following the crowd: brain substrates of long-term memory conformity. Science (2011) 1.74

Encoding of marginal utility across time in the human brain. J Neurosci (2009) 1.74

Preserved verbal memory function in left medial temporal pathology involves reorganisation of function to right medial temporal lobe. Neuroimage (2003) 1.73

Activity in the human brain predicting differential heart rate responses to emotional facial expressions. Neuroimage (2004) 1.71

The nose smells what the eye sees: crossmodal visual facilitation of human olfactory perception. Neuron (2003) 1.70

Go and no-go learning in reward and punishment: interactions between affect and effect. Neuroimage (2012) 1.69

Action dominates valence in anticipatory representations in the human striatum and dopaminergic midbrain. J Neurosci (2011) 1.68

Integrated neural representations of odor intensity and affective valence in human amygdala. J Neurosci (2005) 1.67

The anatomy of choice: active inference and agency. Front Hum Neurosci (2013) 1.66

Modulation of spatial attention by fear-conditioned stimuli: an event-related fMRI study. Neuropsychologia (2002) 1.65

Knowing how much you don't know: a neural organization of uncertainty estimates. Nat Rev Neurosci (2012) 1.65

Disentangling the roles of approach, activation and valence in instrumental and pavlovian responding. PLoS Comput Biol (2011) 1.63

Explaining modulation of reasoning by belief. Cognition (2003) 1.63

Maintenance versus manipulation in verbal working memory revisited: an fMRI study. Neuroimage (2003) 1.63

Risk-dependent reward value signal in human prefrontal cortex. Proc Natl Acad Sci U S A (2009) 1.63

Dissociable codes of odor quality and odorant structure in human piriform cortex. Neuron (2006) 1.63

Dopamine, time, and impulsivity in humans. J Neurosci (2010) 1.63

Impulsive choice and response in dopamine agonist-related impulse control behaviors. Psychopharmacology (Berl) (2009) 1.62

Prefrontal contributions to metacognition in perceptual decision making. J Neurosci (2012) 1.61

A genetically mediated bias in decision making driven by failure of amygdala control. J Neurosci (2009) 1.59

The neurobiology of reference-dependent value computation. J Neurosci (2009) 1.58

Anticipation of novelty recruits reward system and hippocampus while promoting recollection. Neuroimage (2007) 1.58

fMRI activity patterns in human LOC carry information about object exemplars within category. J Cogn Neurosci (2008) 1.57

Abnormal ventral frontal response during performance of an affective go/no go task in patients with mania. Biol Psychiatry (2004) 1.56

Levels of appraisal: a medial prefrontal role in high-level appraisal of emotional material. Neuroimage (2006) 1.55