PubRank

Kazumasa Wakamatsu

Author PubWeight™ 113.77‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling. Proc Natl Acad Sci U S A 2005 2.58
2 Topical drug rescue strategy and skin protection based on the role of Mc1r in UV-induced tanning. Nature 2006 2.09
3 UV-induced DNA damage and melanin content in human skin differing in racial/ethnic origin. FASEB J 2003 1.88
4 Current challenges in understanding melanogenesis: bridging chemistry, biological control, morphology, and function. Pigment Cell Melanoma Res 2009 1.78
5 Protection against UVR involves MC1R-mediated non-pigmentary and pigmentary mechanisms in vivo. J Invest Dermatol 2010 1.65
6 Comparison of structural and chemical properties of black and red human hair melanosomes. Photochem Photobiol 2005 1.54
7 Chemistry of mixed melanogenesis--pivotal roles of dopaquinone. Photochem Photobiol 2008 1.47
8 Serum levels of pigmentation markers are elevated in patients undergoing hemodialysis. Blood Purif 2007 1.46
9 Predicting phenotype from genotype: normal pigmentation. J Forensic Sci 2010 1.43
10 Regulation of human skin pigmentation and responses to ultraviolet radiation. Pigment Cell Res 2007 1.41
11 Ion-exchange and adsorption of Fe(III) by Sepia melanin. Pigment Cell Res 2004 1.32
12 Usefulness of alkaline hydrogen peroxide oxidation to analyze eumelanin and pheomelanin in various tissue samples: application to chemical analysis of human hair melanins. Pigment Cell Melanoma Res 2011 1.31
13 Melanin acts as a potent UVB photosensitizer to cause an atypical mode of cell death in murine skin. Proc Natl Acad Sci U S A 2004 1.31
14 Slc7a11 gene controls production of pheomelanin pigment and proliferation of cultured cells. Proc Natl Acad Sci U S A 2005 1.28
15 Quantitative analysis of eumelanin and pheomelanin in humans, mice, and other animals: a comparative review. Pigment Cell Res 2003 1.26
16 Melanins and melanogenesis: methods, standards, protocols. Pigment Cell Melanoma Res 2013 1.23
17 Melanocortin 1 receptor genotype: an important determinant of the damage response of melanocytes to ultraviolet radiation. FASEB J 2010 1.23
18 Interaction of Hermansky-Pudlak Syndrome genes in the regulation of lysosome-related organelles. Traffic 2006 1.23
19 Identification of glypican-3 as a novel tumor marker for melanoma. Clin Cancer Res 2004 1.22
20 Strength and cost of an induced immune response are associated with a heritable melanin-based colour trait in female tawny owls. J Anim Ecol 2009 1.21
21 Melanin content and MC1R function independently affect UVR-induced DNA damage in cultured human melanocytes. Pigment Cell Res 2006 1.20
22 Human melanocortin 1 receptor variants, receptor function and melanocyte response to UV radiation. J Cell Sci 2002 1.19
23 Comparisons of the structural and chemical properties of melanosomes isolated from retinal pigment epithelium, iris and choroid of newborn and mature bovine eyes. Photochem Photobiol 2005 1.18
24 Adaptive melanin response of the soil fungus Aspergillus niger to UV radiation stress at "Evolution Canyon", Mount Carmel, Israel. PLoS One 2008 1.17
25 Independent regulation of hair and skin color by two G protein-coupled pathways. Pigment Cell Melanoma Res 2009 1.16
26 Direct chemical evidence for eumelanin pigment from the Jurassic period. Proc Natl Acad Sci U S A 2012 1.14
27 Quantitative measures of the effect of the melanocortin 1 receptor on human pigmentary status. J Invest Dermatol 2004 1.13
28 The neuromelanin of human substantia nigra: physiological and pathogenic aspects. Pigment Cell Res 2004 1.12
29 Cutaneous photobiology. The melanocyte vs. the sun: who will win the final round? Pigment Cell Res 2003 1.07
30 New melanic pigments in the human brain that accumulate in aging and block environmental toxic metals. Proc Natl Acad Sci U S A 2008 1.07
31 Regulation of eumelanin/pheomelanin synthesis and visible pigmentation in melanocytes by ligands of the melanocortin 1 receptor. Pigment Cell Melanoma Res 2008 1.07
32 Pael receptor induces death of dopaminergic neurons in the substantia nigra via endoplasmic reticulum stress and dopamine toxicity, which is enhanced under condition of parkin inactivation. Hum Mol Genet 2006 1.06
33 4-S-Cysteaminylphenol-loaded magnetite cationic liposomes for combination therapy of hyperthermia with chemotherapy against malignant melanoma. Cancer Sci 2007 1.06
34 Agouti protein, mahogunin, and attractin in pheomelanogenesis and melanoblast-like alteration of melanocytes: a cAMP-independent pathway. Pigment Cell Melanoma Res 2009 1.02
35 Molecular and phenotypic analysis of 25 recessive, homozygous-viable alleles at the mouse agouti locus. Genetics 2002 1.02
36 Raman spectroscopy as a non-invasive technique for the quantification of melanins in feathers and hairs. Pigment Cell Melanoma Res 2013 0.98
37 Pigmentation effects of solar-simulated radiation as compared with UVA and UVB radiation. Pigment Cell Melanoma Res 2008 0.97
38 Inactivation of Pmel alters melanosome shape but has only a subtle effect on visible pigmentation. PLoS Genet 2011 0.97
39 Unexpected endocrine features and normal pigmentation in a young adult patient carrying a novel homozygous mutation in the POMC gene. J Clin Endocrinol Metab 2008 0.95
40 Comparison of the structural and physical properties of human hair eumelanin following enzymatic or acid/base extraction. Pigment Cell Res 2003 0.94
41 Eumelanin and pheomelanin concentrations in human epidermis before and after UVB irradiation. Pigment Cell Res 2005 0.94
42 Human hair melanins: what we have learned and have not learned from mouse coat color pigmentation. Pigment Cell Melanoma Res 2011 0.93
43 Tyrosinase-related proteins suppress tyrosinase-mediated cell death of melanocytes and melanoma cells. Exp Cell Res 2004 0.92
44 Characterization of the pigment produced by the planarian, Dugesia ryukyuensis. Pigment Cell Res 2006 0.92
45 Cutaneous photoprotection and melanoma susceptibility: reaching beyond melanin content to the frontiers of DNA repair. Front Biosci 2006 0.92
46 Vibrational characterization of pheomelanin and trichochrome F by Raman spectroscopy. Spectrochim Acta A Mol Biomol Spectrosc 2013 0.91
47 Melanoma-targeted chemo-thermo-immuno (CTI)-therapy using N-propionyl-4-S-cysteaminylphenol-magnetite nanoparticles elicits CTL response via heat shock protein-peptide complex release. Cancer Sci 2010 0.90
48 Stem cell factor rescues tyrosinase expression and pigmentation in discreet anatomic locations in albino mice. Pigment Cell Melanoma Res 2009 0.89
49 Regulation of DHICA-mediated antioxidation by dopachrome tautomerase: implication for skin photoprotection against UVA radiation. Free Radic Biol Med 2010 0.88
50 Spiny mice modulate eumelanin to pheomelanin ratio to achieve cryptic coloration in "evolution canyon," Israel. PLoS One 2010 0.88
51 High prevalence of cataracts in birds with pheomelanin-based colouration. Comp Biochem Physiol A Mol Integr Physiol 2012 0.87
52 Influence of alpha-melanocyte-stimulating hormone and ultraviolet radiation on the transfer of melanosomes to keratinocytes. FASEB J 2001 0.87
53 Mutations in dopachrome tautomerase (Dct) affect eumelanin/pheomelanin synthesis, but do not affect intracellular trafficking of the mutant protein. Biochem J 2005 0.87
54 Agaritine purified from Agaricus blazei Murrill exerts anti-tumor activity against leukemic cells. Biochim Biophys Acta 2010 0.86
55 Highly sensitive detection of melanoma at an early stage based on the increased serum secreted protein acidic and rich in cysteine and glypican-3 levels. Clin Cancer Res 2005 0.84
56 N-propionyl-cysteaminylphenol-magnetite conjugate (NPrCAP/M) is a nanoparticle for the targeted growth suppression of melanoma cells. J Invest Dermatol 2009 0.84
57 Low-quality birds do not display high-quality signals: The cysteine-pheomelanin mechanism of honesty. Evolution 2014 0.83
58 Sexual dimorphism in melanin pigmentation, feather coloration and its heritability in the barn swallow (Hirundo rustica). PLoS One 2013 0.83
59 Variants in melanogenesis-related genes associate with skin cancer risk among Japanese populations. J Dermatol 2014 0.83
60 Neutral pH and copper ions promote eumelanogenesis after the dopachrome stage. Pigment Cell Melanoma Res 2013 0.83
61 Pael receptor is involved in dopamine metabolism in the nigrostriatal system. Neurosci Res 2007 0.82
62 Prolonged treatment of fair-skinned mice with topical forskolin causes persistent tanning and UV protection. Pigment Cell Melanoma Res 2008 0.82
63 An oxygen transporter hemocyanin can act on the late pathway of melanin synthesis. Pigment Cell Res 2005 0.82
64 The mouse pink-eyed dilution allele of the P-gene greatly inhibits eumelanin but not pheomelanin synthesis. Pigment Cell Melanoma Res 2010 0.82
65 Pigment-independent cAMP-mediated epidermal thickening protects against cutaneous UV injury by keratinocyte proliferation. Exp Dermatol 2012 0.82
66 Effects of melanogenesis-inducing nitric oxide and histamine on the production of eumelanin and pheomelanin in cultured human melanocytes. Pigment Cell Res 2003 0.81
67 Short- and long-term effects of UV radiation on the pigmentation of human skin. J Investig Dermatol Symp Proc 2009 0.81
68 T-cell receptor repertoires of tumor-infiltrating lymphocytes after hyperthermia using functionalized magnetite nanoparticles. Nanomedicine (Lond) 2012 0.81
69 An extract of Withania somnifera attenuates endothelin-1-stimulated pigmentation in human epidermal equivalents through the interruption of PKC activity within melanocytes. Phytother Res 2011 0.81
70 Effects of genic substitution at the pink-eyed dilution locus on the proliferation and differentiation of mouse epidermal melanocytes in vivo and in vitro. J Exp Zool 2002 0.81
71 Phenotypic expression of melanocortin-1 receptor mutations in Black Jamaicans. J Invest Dermatol 2003 0.81
72 Comparison of the quantity of cochlear melanin in young and old C57BL/6 mice. Arch Otolaryngol Head Neck Surg 2007 0.81
73 An extract of Melia toosendan attenuates endothelin-1-stimulated pigmentation in human epidermal equivalents through the interruption of PKC activity within melanocytes. Arch Dermatol Res 2011 0.81
74 Growth inhibition of re-challenge B16 melanoma transplant by conjugates of melanogenesis substrate and magnetite nanoparticles as the basis for developing melanoma-targeted chemo-thermo-immunotherapy. J Biomed Biotechnol 2009 0.81
75 Cystinosin is a melanosomal protein that regulates melanin synthesis. FASEB J 2012 0.80
76 Estrogen increases hair pigmentation in female recessive yellow mice. Zoolog Sci 2010 0.80
77 Tyrosinase-catalyzed oxidation of rhododendrol produces 2-methylchromane-6,7-dione, the putative ultimate toxic metabolite: implications for melanocyte toxicity. Pigment Cell Melanoma Res 2014 0.80
78 A novel RFP-RET transgenic mouse model with abundant eumelanin in the cochlea. Hear Res 2004 0.80
79 The mouse brown (b/Tyrp1(b) ) allele does not affect pheomelanin synthesis in mice. Zoolog Sci 2014 0.79
80 Abrogating effect of a xanthophyll carotenoid astaxanthin on the stem cell factor-induced stimulation of human epidermal pigmentation. Arch Dermatol Res 2012 0.79
81 Increased cysteinyldopa plasma levels hint to melanocyte as stress sensor in psoriasis. Exp Dermatol 2011 0.79
82 Comparison of eumelanin and pheomelanin content between cultured uveal melanoma cells and normal uveal melanocytes. Melanoma Res 2009 0.79
83 Excess tyrosine rescues the reduced activity of proliferation and differentiation of cultured recessive yellow melanocytes derived from neonatal mouse epidermis. Eur J Cell Biol 2007 0.79
84 Photoaging of human retinal pigment epithelium is accompanied by oxidative modifications of its eumelanin. Pigment Cell Melanoma Res 2013 0.79
85 Purification and growth of melanocortin 1 receptor (Mc1r)- defective primary murine melanocytes is dependent on stem cell factor (SFC) from keratinocyte-conditioned media. In Vitro Cell Dev Biol Anim 2009 0.78
86 Stimulation of the proliferation and differentiation of mouse pink-eyed dilution epidermal melanocytes by excess tyrosine in serum-free primary culture. J Cell Physiol 2002 0.78
87 Childhood malnutrition is associated with a reduction in the total melanin content of scalp hair. Br J Nutr 2007 0.78
88 Pheomelanin production in the epidermis from newborn agouti mice is induced by the expression of the agouti gene in the dermis. Pigment Cell Res 2004 0.78
89 Viability is associated with melanin-based coloration in the barn swallow (Hirundo rustica). PLoS One 2013 0.77
90 Ultrafast absorption and photothermal studies of decarboxytrichochrome C in solution. Photochem Photobiol Sci 2003 0.77
91 The histological analysis, colorimetric evaluation, and chemical quantification of melanin content in 'suntanned' fish. Pigment Cell Res 2005 0.77
92 Neuromelanins of human brain have soluble and insoluble components with dolichols attached to the melanic structure. PLoS One 2012 0.77
93 Withania somnifera extract attenuates stem cell factor-stimulated pigmentation in human epidermal equivalents through interruption of ERK phosphorylation within melanocytes. J Nat Med 2011 0.77
94 Excess tyrosine stimulates eumelanin and pheomelanin synthesis in cultured slaty melanocytes from neonatal mouse epidermis. Zoolog Sci 2007 0.77
95 Tyrosinase-catalyzed metabolism of rhododendrol (RD) in B16 melanoma cells: production of RD-pheomelanin and covalent binding with thiol proteins. Pigment Cell Melanoma Res 2015 0.77
96 High levels of melanin-related metabolites in plasma from pink-eyed dilution mice. Pigment Cell Res 2007 0.77
97 Maintenance of immune hyporesponsiveness to melanosomal proteins by DHICA-mediated antioxidation: Possible implications for autoimmune vitiligo. Free Radic Biol Med 2011 0.77
98 Degree of polymerization of 5,6-dihydroxyindole-derived eumelanin from chemical degradation study. Pigment Cell Melanoma Res 2014 0.77
99 The slaty mutation affects eumelanin and pheomelanin synthesis in mouse melanocytes. Eur J Cell Biol 2006 0.77
100 Adaptation of pelage color and pigment variations in Israeli subterranean blind mole rats, Spalax ehrenbergi [corrected]. PLoS One 2013 0.77
101 1-(2,4-Dihydroxyphenyl)-3-(2,4-dimethoxy-3-methylpheny)propane inhibits melanin synthesis by dual mechanisms. J Dermatol Sci 2011 0.77
102 Human tyrosinase is able to oxidize both enantiomers of rhododendrol. Pigment Cell Melanoma Res 2014 0.77
103 Inhibition of transglutaminase by synthetic tyrosine melanin. Biosci Biotechnol Biochem 2002 0.76
104 Gamma-glutamyl transpeptidase and its role in melanogenesis: redox reactions and regulation of tyrosinase. Pigment Cell Res 2002 0.76
105 Isomeric cysteinyldopas provide a (photo)degradable bulk component and a robust structural element in red human hair pheomelanin. Pigment Cell Melanoma Res 2009 0.76
106 N-propionyl-4-S-cysteaminylphenol induces apoptosis in B16F1 cells and mediates tumor-specific T-cell immune responses in a mouse melanoma model. J Dermatol Sci 2012 0.76
107 Mechanism of putative neo-antigen formation from N-propionyl-4-S-cysteaminylphenol, a tyrosinase substrate, in melanoma models. Biochem Pharmacol 2012 0.76
108 Black bib size is associated with feather content of pheomelanin in male house sparrows. Pigment Cell Melanoma Res 2014 0.76
109 The mouse ruby-eye 2(d) (ru2(d) /Hps5(ru2-d) ) allele inhibits eumelanin but not pheomelanin synthesis. Pigment Cell Melanoma Res 2013 0.76
110 Changes in the proliferation and differentiation of neonatal mouse pink-eyed dilution melanocytes in the presence of excess tyrosine. Pigment Cell Res 2003 0.76
111 Melanin-based iridescent feather color in the Jungle Crow. J Vet Med Sci 2009 0.76
112 A new mutation of mouse ruby-eye 2, ru2(d)/Hps5(ru2-d) inhibits eumelanin synthesis but stimulates pheomelanin synthesis in melanocytes. Zoolog Sci 2012 0.76
113 A close relationship between androgen levels and eumelanogenesis in the teleost red seabream (Pagrus major): Quantitative analysis of its seasonal variation and effects of oral treatment with methyl-testosterone. Comp Biochem Physiol A Mol Integr Physiol 2010 0.76
114 Possible oxidative polymerization mechanism of 5,6-dihydroxyindole from ab initio calculations. J Phys Chem A 2008 0.76
115 Effects of Aloe-emodin and Emodin on Proliferation of the MKN45 Human Gastric Cancer Cell Line. Asian Pac J Cancer Prev 2015 0.76
116 Melanoma-Targeted Chemothermotherapy and In Situ Peptide Immunotherapy through HSP Production by Using Melanogenesis Substrate, NPrCAP, and Magnetite Nanoparticles. J Skin Cancer 2013 0.76
117 High-performance liquid chromatography estimation of cross-linking of dihydroxyindole moiety in eumelanin. Anal Biochem 2012 0.76
118 A novel deletion mutation of mouse ruby-eye 2 named ru2(d)/Hps5(ru2-d) inhibits melanocyte differentiation and its impaired differentiation is rescued by L-tyrosine. Zoolog Sci 2011 0.76
119 Effect of infrared radiation A on photoaged hairless mice harboring eumelanin and pheomelanin in the epidermis. J Dermatol 2015 0.75
120 Synthesis and selective in vitro anti-melanoma effect of enantiomeric alpha-methyl- and alpha-ethyl-4-S-cysteaminylphenol. Melanoma Res 2003 0.75
121 Inhibitory effects of low-dose aloe-emodin on the development of colorectal tumors in min mice. Asian Pac J Cancer Prev 2014 0.75
122 HPLC analysis of pheomelanin degradation products in human urine. Pigment Cell Res 2003 0.75
123 Imaging, chemical and spectroscopic studies of the methylation-induced decomposition of melanosomes. Photochem Photobiol 2010 0.75
124 Comparison of in vivo anti-melanoma effect of enantiomeric alpha-methyl- and alpha-ethyl-4-S-cysteaminylphenol. Melanoma Res 2004 0.75
125 Serum levels of 5-s-cysteinyldopa are correlated with skin colors in hemodialysis patients but not in peritoneal dialysis patients. Blood Purif 2009 0.75
126 The eumelanin and pheomelanin contents in dorsal hairs of female recessive yellow mice are greater than in male. J Dermatol Sci 2006 0.75