PubRank

Shosuke Ito

Author PubWeight™ 100.74‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling. Proc Natl Acad Sci U S A 2005 2.58
2 Topical drug rescue strategy and skin protection based on the role of Mc1r in UV-induced tanning. Nature 2006 2.09
3 UV-induced DNA damage and melanin content in human skin differing in racial/ethnic origin. FASEB J 2003 1.88
4 Advanced chemical methods in melanin determination. Pigment Cell Res 2002 1.78
5 Current challenges in understanding melanogenesis: bridging chemistry, biological control, morphology, and function. Pigment Cell Melanoma Res 2009 1.78
6 Protection against UVR involves MC1R-mediated non-pigmentary and pigmentary mechanisms in vivo. J Invest Dermatol 2010 1.65
7 Chemical analysis of late stages of pheomelanogenesis: conversion of dihydrobenzothiazine to a benzothiazole structure. Pigment Cell Melanoma Res 2009 1.62
8 Comparison of structural and chemical properties of black and red human hair melanosomes. Photochem Photobiol 2005 1.54
9 Serum levels of pigmentation markers are elevated in patients undergoing hemodialysis. Blood Purif 2007 1.46
10 Predicting phenotype from genotype: normal pigmentation. J Forensic Sci 2010 1.43
11 Regulation of human skin pigmentation and responses to ultraviolet radiation. Pigment Cell Res 2007 1.41
12 Ion-exchange and adsorption of Fe(III) by Sepia melanin. Pigment Cell Res 2004 1.32
13 Melanin acts as a potent UVB photosensitizer to cause an atypical mode of cell death in murine skin. Proc Natl Acad Sci U S A 2004 1.31
14 Slc7a11 gene controls production of pheomelanin pigment and proliferation of cultured cells. Proc Natl Acad Sci U S A 2005 1.28
15 The structure of neuromelanin as studied by chemical degradative methods. J Neurochem 2003 1.24
16 Melanins and melanogenesis: methods, standards, protocols. Pigment Cell Melanoma Res 2013 1.23
17 Melanocortin 1 receptor genotype: an important determinant of the damage response of melanocytes to ultraviolet radiation. FASEB J 2010 1.23
18 Interaction of Hermansky-Pudlak Syndrome genes in the regulation of lysosome-related organelles. Traffic 2006 1.23
19 Identification of glypican-3 as a novel tumor marker for melanoma. Clin Cancer Res 2004 1.22
20 Melanin content and MC1R function independently affect UVR-induced DNA damage in cultured human melanocytes. Pigment Cell Res 2006 1.20
21 Human melanocortin 1 receptor variants, receptor function and melanocyte response to UV radiation. J Cell Sci 2002 1.19
22 Comparisons of the structural and chemical properties of melanosomes isolated from retinal pigment epithelium, iris and choroid of newborn and mature bovine eyes. Photochem Photobiol 2005 1.18
23 Adaptive melanin response of the soil fungus Aspergillus niger to UV radiation stress at "Evolution Canyon", Mount Carmel, Israel. PLoS One 2008 1.17
24 Independent regulation of hair and skin color by two G protein-coupled pathways. Pigment Cell Melanoma Res 2009 1.16
25 Direct chemical evidence for eumelanin pigment from the Jurassic period. Proc Natl Acad Sci U S A 2012 1.14
26 Quantitative measures of the effect of the melanocortin 1 receptor on human pigmentary status. J Invest Dermatol 2004 1.13
27 The usefulness of 4-amino-3-hydroxyphenylalanine as a specific marker of pheomelanin. Pigment Cell Res 2002 1.13
28 The neuromelanin of human substantia nigra: physiological and pathogenic aspects. Pigment Cell Res 2004 1.12
29 Cutaneous photobiology. The melanocyte vs. the sun: who will win the final round? Pigment Cell Res 2003 1.07
30 New melanic pigments in the human brain that accumulate in aging and block environmental toxic metals. Proc Natl Acad Sci U S A 2008 1.07
31 Regulation of eumelanin/pheomelanin synthesis and visible pigmentation in melanocytes by ligands of the melanocortin 1 receptor. Pigment Cell Melanoma Res 2008 1.07
32 Pael receptor induces death of dopaminergic neurons in the substantia nigra via endoplasmic reticulum stress and dopamine toxicity, which is enhanced under condition of parkin inactivation. Hum Mol Genet 2006 1.06
33 4-S-Cysteaminylphenol-loaded magnetite cationic liposomes for combination therapy of hyperthermia with chemotherapy against malignant melanoma. Cancer Sci 2007 1.06
34 Agouti protein, mahogunin, and attractin in pheomelanogenesis and melanoblast-like alteration of melanocytes: a cAMP-independent pathway. Pigment Cell Melanoma Res 2009 1.02
35 Molecular and phenotypic analysis of 25 recessive, homozygous-viable alleles at the mouse agouti locus. Genetics 2002 1.02
36 Pigmentation effects of solar-simulated radiation as compared with UVA and UVB radiation. Pigment Cell Melanoma Res 2008 0.97
37 Inactivation of Pmel alters melanosome shape but has only a subtle effect on visible pigmentation. PLoS Genet 2011 0.97
38 Unexpected endocrine features and normal pigmentation in a young adult patient carrying a novel homozygous mutation in the POMC gene. J Clin Endocrinol Metab 2008 0.95
39 Comparison of the structural and physical properties of human hair eumelanin following enzymatic or acid/base extraction. Pigment Cell Res 2003 0.94
40 Eumelanin and pheomelanin concentrations in human epidermis before and after UVB irradiation. Pigment Cell Res 2005 0.94
41 Diversity of pigmentation in cultured human melanocytes is due to differences in the type as well as quantity of melanin. Pigment Cell Res 2006 0.93
42 Tyrosinase-related proteins suppress tyrosinase-mediated cell death of melanocytes and melanoma cells. Exp Cell Res 2004 0.92
43 Cutaneous photoprotection and melanoma susceptibility: reaching beyond melanin content to the frontiers of DNA repair. Front Biosci 2006 0.92
44 Melanoma-targeted chemo-thermo-immuno (CTI)-therapy using N-propionyl-4-S-cysteaminylphenol-magnetite nanoparticles elicits CTL response via heat shock protein-peptide complex release. Cancer Sci 2010 0.90
45 Characterization of melanin in human iridal and choroidal melanocytes from eyes with various colored irides. Pigment Cell Melanoma Res 2008 0.90
46 Stem cell factor rescues tyrosinase expression and pigmentation in discreet anatomic locations in albino mice. Pigment Cell Melanoma Res 2009 0.89
47 UVA-induced oxidative degradation of melanins: fission of indole moiety in eumelanin and conversion to benzothiazole moiety in pheomelanin. Pigment Cell Melanoma Res 2012 0.89
48 Spiny mice modulate eumelanin to pheomelanin ratio to achieve cryptic coloration in "evolution canyon," Israel. PLoS One 2010 0.88
49 Mutations in dopachrome tautomerase (Dct) affect eumelanin/pheomelanin synthesis, but do not affect intracellular trafficking of the mutant protein. Biochem J 2005 0.87
50 Influence of alpha-melanocyte-stimulating hormone and ultraviolet radiation on the transfer of melanosomes to keratinocytes. FASEB J 2001 0.87
51 Agaritine purified from Agaricus blazei Murrill exerts anti-tumor activity against leukemic cells. Biochim Biophys Acta 2010 0.86
52 Human iridal stroma melanosomes of varying pheomelanin contents possess a common eumelanic outer surface. J Phys Chem B 2009 0.85
53 Highly sensitive detection of melanoma at an early stage based on the increased serum secreted protein acidic and rich in cysteine and glypican-3 levels. Clin Cancer Res 2005 0.84
54 N-propionyl-cysteaminylphenol-magnetite conjugate (NPrCAP/M) is a nanoparticle for the targeted growth suppression of melanoma cells. J Invest Dermatol 2009 0.84
55 Variants in melanogenesis-related genes associate with skin cancer risk among Japanese populations. J Dermatol 2014 0.83
56 Pael receptor is involved in dopamine metabolism in the nigrostriatal system. Neurosci Res 2007 0.82
57 An oxygen transporter hemocyanin can act on the late pathway of melanin synthesis. Pigment Cell Res 2005 0.82
58 The mouse pink-eyed dilution allele of the P-gene greatly inhibits eumelanin but not pheomelanin synthesis. Pigment Cell Melanoma Res 2010 0.82
59 Prolonged treatment of fair-skinned mice with topical forskolin causes persistent tanning and UV protection. Pigment Cell Melanoma Res 2008 0.82
60 Pigment-independent cAMP-mediated epidermal thickening protects against cutaneous UV injury by keratinocyte proliferation. Exp Dermatol 2012 0.82
61 Common anti-apoptotic roles of parkin and alpha-synuclein in human dopaminergic cells. Biochem Biophys Res Commun 2005 0.81
62 T-cell receptor repertoires of tumor-infiltrating lymphocytes after hyperthermia using functionalized magnetite nanoparticles. Nanomedicine (Lond) 2012 0.81
63 Growth inhibition of re-challenge B16 melanoma transplant by conjugates of melanogenesis substrate and magnetite nanoparticles as the basis for developing melanoma-targeted chemo-thermo-immunotherapy. J Biomed Biotechnol 2009 0.81
64 Short- and long-term effects of UV radiation on the pigmentation of human skin. J Investig Dermatol Symp Proc 2009 0.81
65 Effects of melanogenesis-inducing nitric oxide and histamine on the production of eumelanin and pheomelanin in cultured human melanocytes. Pigment Cell Res 2003 0.81
66 Effects of genic substitution at the pink-eyed dilution locus on the proliferation and differentiation of mouse epidermal melanocytes in vivo and in vitro. J Exp Zool 2002 0.81
67 Cystinosin is a melanosomal protein that regulates melanin synthesis. FASEB J 2012 0.80
68 Melanins seem to be everywhere in the body, but for what? Pigment Cell Melanoma Res 2008 0.80
69 Estrogen increases hair pigmentation in female recessive yellow mice. Zoolog Sci 2010 0.80
70 A novel RFP-RET transgenic mouse model with abundant eumelanin in the cochlea. Hear Res 2004 0.80
71 The mouse brown (b/Tyrp1(b) ) allele does not affect pheomelanin synthesis in mice. Zoolog Sci 2014 0.79
72 Increased cysteinyldopa plasma levels hint to melanocyte as stress sensor in psoriasis. Exp Dermatol 2011 0.79
73 Comparison of eumelanin and pheomelanin content between cultured uveal melanoma cells and normal uveal melanocytes. Melanoma Res 2009 0.79
74 Excess tyrosine rescues the reduced activity of proliferation and differentiation of cultured recessive yellow melanocytes derived from neonatal mouse epidermis. Eur J Cell Biol 2007 0.79
75 Evaluation of melanin-related metabolites as markers of solar ultraviolet-B radiation. Pigment Cell Res 2006 0.78
76 Stimulation of the proliferation and differentiation of mouse pink-eyed dilution epidermal melanocytes by excess tyrosine in serum-free primary culture. J Cell Physiol 2002 0.78
77 Biosynthetic pathway to neuromelanin and its aging process. Pigment Cell Melanoma Res 2012 0.78
78 Purification and growth of melanocortin 1 receptor (Mc1r)- defective primary murine melanocytes is dependent on stem cell factor (SFC) from keratinocyte-conditioned media. In Vitro Cell Dev Biol Anim 2009 0.78
79 Childhood malnutrition is associated with a reduction in the total melanin content of scalp hair. Br J Nutr 2007 0.78
80 Pheomelanin production in the epidermis from newborn agouti mice is induced by the expression of the agouti gene in the dermis. Pigment Cell Res 2004 0.78
81 Determination of eumelanin in human urine. Pigment Cell Res 2006 0.77
82 Ultrafast absorption and photothermal studies of decarboxytrichochrome C in solution. Photochem Photobiol Sci 2003 0.77
83 Adaptation of pelage color and pigment variations in Israeli subterranean blind mole rats, Spalax ehrenbergi [corrected]. PLoS One 2013 0.77
84 The slaty mutation affects eumelanin and pheomelanin synthesis in mouse melanocytes. Eur J Cell Biol 2006 0.77
85 The histological analysis, colorimetric evaluation, and chemical quantification of melanin content in 'suntanned' fish. Pigment Cell Res 2005 0.77
86 Excess tyrosine stimulates eumelanin and pheomelanin synthesis in cultured slaty melanocytes from neonatal mouse epidermis. Zoolog Sci 2007 0.77
87 1-(2,4-Dihydroxyphenyl)-3-(2,4-dimethoxy-3-methylpheny)propane inhibits melanin synthesis by dual mechanisms. J Dermatol Sci 2011 0.77
88 Neuromelanins of human brain have soluble and insoluble components with dolichols attached to the melanic structure. PLoS One 2012 0.77
89 Degree of polymerization of 5,6-dihydroxyindole-derived eumelanin from chemical degradation study. Pigment Cell Melanoma Res 2014 0.77
90 High levels of melanin-related metabolites in plasma from pink-eyed dilution mice. Pigment Cell Res 2007 0.77
91 Changes in the proliferation and differentiation of neonatal mouse pink-eyed dilution melanocytes in the presence of excess tyrosine. Pigment Cell Res 2003 0.76
92 Possible oxidative polymerization mechanism of 5,6-dihydroxyindole from ab initio calculations. J Phys Chem A 2008 0.76
93 Inhibition of transglutaminase by synthetic tyrosine melanin. Biosci Biotechnol Biochem 2002 0.76
94 A close relationship between androgen levels and eumelanogenesis in the teleost red seabream (Pagrus major): Quantitative analysis of its seasonal variation and effects of oral treatment with methyl-testosterone. Comp Biochem Physiol A Mol Integr Physiol 2010 0.76
95 N-propionyl-4-S-cysteaminylphenol induces apoptosis in B16F1 cells and mediates tumor-specific T-cell immune responses in a mouse melanoma model. J Dermatol Sci 2012 0.76
96 Melanoma-Targeted Chemothermotherapy and In Situ Peptide Immunotherapy through HSP Production by Using Melanogenesis Substrate, NPrCAP, and Magnetite Nanoparticles. J Skin Cancer 2013 0.76
97 Gamma-glutamyl transpeptidase and its role in melanogenesis: redox reactions and regulation of tyrosinase. Pigment Cell Res 2002 0.76
98 A novel deletion mutation of mouse ruby-eye 2 named ru2(d)/Hps5(ru2-d) inhibits melanocyte differentiation and its impaired differentiation is rescued by L-tyrosine. Zoolog Sci 2011 0.76
99 Isomeric cysteinyldopas provide a (photo)degradable bulk component and a robust structural element in red human hair pheomelanin. Pigment Cell Melanoma Res 2009 0.76
100 The mouse ruby-eye 2(d) (ru2(d) /Hps5(ru2-d) ) allele inhibits eumelanin but not pheomelanin synthesis. Pigment Cell Melanoma Res 2013 0.76
101 A new mutation of mouse ruby-eye 2, ru2(d)/Hps5(ru2-d) inhibits eumelanin synthesis but stimulates pheomelanin synthesis in melanocytes. Zoolog Sci 2012 0.76
102 Case of Hermansky-Pudlak syndrome 1 patient with milder symptoms in Japanese. J Dermatol 2014 0.75
103 Serum levels of 5-s-cysteinyldopa are correlated with skin colors in hemodialysis patients but not in peritoneal dialysis patients. Blood Purif 2009 0.75
104 Comparison of phaeomelanin and its precursor 5-S-cysteinyldopa in the serum of melanoma patients. Melanoma Res 2003 0.75
105 HPLC analysis of pheomelanin degradation products in human urine. Pigment Cell Res 2003 0.75
106 Comparison of in vivo anti-melanoma effect of enantiomeric alpha-methyl- and alpha-ethyl-4-S-cysteaminylphenol. Melanoma Res 2004 0.75
107 Tyrosine peptides provide a color palette upon tyrosinase oxidation: nanosize does matter. Pigment Cell Melanoma Res 2016 0.75
108 Imaging, chemical and spectroscopic studies of the methylation-induced decomposition of melanosomes. Photochem Photobiol 2010 0.75
109 Synthesis and selective in vitro anti-melanoma effect of enantiomeric alpha-methyl- and alpha-ethyl-4-S-cysteaminylphenol. Melanoma Res 2003 0.75
110 The eumelanin and pheomelanin contents in dorsal hairs of female recessive yellow mice are greater than in male. J Dermatol Sci 2006 0.75