Effect of sodium chloride on the release, absorption and safety of diclofenac sodium delivered by poloxamer gel.

PubWeight™: 0.90‹?›

🔗 View Article (PMID 12954185)

Published in Int J Pharm on September 16, 2003

Authors

Young-Joon Park1, Chul Soon Yong, Hak-Mi Kim, Jong-Dal Rhee, Yu-Kyoung Oh, Chong-Kook Kim, Han-Gon Choi

Author Affiliations

1: College of Pharmacy, Seoul National University, San 56-1, Shinlim-Dong, Kwanak-Ku, Seoul 151-742, South Korea.

Articles by these authors

Cellular uptake mechanism and intracellular fate of hydrophobically modified glycol chitosan nanoparticles. J Control Release (2009) 1.81

siRNA conjugate delivery systems. Bioconjug Chem (2009) 1.69

Enhanced oral bioavailability of flurbiprofen by combined use of micelle solution and inclusion compound. Arch Pharm Res (2010) 1.41

Enhanced oral bioavailability of dexibuprofen by a novel solid self-emulsifying drug delivery system (SEDDS). Eur J Pharm Biopharm (2009) 1.33

Gel characterisation and in vivo evaluation of minocycline-loaded wound dressing with enhanced wound healing using polyvinyl alcohol and chitosan. Int J Pharm (2010) 1.29

Formulation and in vitro assessment of minoxidil niosomes for enhanced skin delivery. Int J Pharm (2009) 1.26

Preparation, characterization and in vivo evaluation of ibuprofen binary solid dispersions with poloxamer 188. Int J Pharm (2007) 1.24

Target-specific intracellular delivery of siRNA using degradable hyaluronic acid nanogels. J Control Release (2007) 1.20

Preparation, characterization and in vitro cytotoxicity of paclitaxel-loaded sterically stabilized solid lipid nanoparticles. Biomaterials (2007) 1.20

Antitumor activity of EGFR targeted pH-sensitive immunoliposomes encapsulating gemcitabine in A549 xenograft nude mice. J Control Release (2009) 1.17

Prolonged antifungal effects of clotrimazole-containing mucoadhesive thermosensitive gels on vaginitis. J Control Release (2002) 1.15

Rheological evaluation of thermosensitive and mucoadhesive vaginal gels in physiological conditions. Int J Pharm (2002) 1.13

Formulation parameters determining the physicochemical characteristics of solid lipid nanoparticles loaded with all-trans retinoic acid. Int J Pharm (2002) 1.12

The NRF2-heme oxygenase-1 system modulates cyclosporin A-induced epithelial-mesenchymal transition and renal fibrosis. Free Radic Biol Med (2010) 1.12

Topical delivery of low-molecular-weight heparin with surface-charged flexible liposomes. Biomaterials (2006) 1.11

Enhanced bioavailability of poorly water-soluble clotrimazole by inclusion with beta-cyclodextrin. Arch Pharm Res (2007) 1.09

Adaptive response to GSH depletion and resistance to L-buthionine-(S,R)-sulfoximine: involvement of Nrf2 activation. Mol Cell Biochem (2008) 1.08

Alterations in promoter usage and expression levels of insulin-like growth factor-II and H19 genes in cervical carcinoma exhibiting biallelic expression of IGF-II. Biochim Biophys Acta (2002) 1.06

Novel valsartan-loaded solid dispersion with enhanced bioavailability and no crystalline changes. Int J Pharm (2011) 1.06

Enhanced oral bioavailability of Coenzyme Q10 by self-emulsifying drug delivery systems. Int J Pharm (2009) 1.06

Development of polyvinyl alcohol-sodium alginate gel-matrix-based wound dressing system containing nitrofurazone. Int J Pharm (2008) 1.05

Tumor specificity and therapeutic efficacy of photosensitizer-encapsulated glycol chitosan-based nanoparticles in tumor-bearing mice. Biomaterials (2009) 1.05

Accelerated cerebral ischemic injury by activated macrophages/microglia after lipopolysaccharide microinjection into rat corpus callosum. Glia (2005) 1.04

Differential expression and polarized secretion of CXC and CC chemokines by human intestinal epithelial cancer cell lines in response to Clostridium difficile toxin A. Microbiol Immunol (2002) 1.04

CpG oligodeoxynucleotides induce IL-8 expression in CD34+ cells via mitogen-activated protein kinase-dependent and NF-kappaB-independent pathways. Int Immunol (2005) 1.02

Vacuolating cytotoxin in Helicobacter pylori water-soluble proteins upregulates chemokine expression in human eosinophils via Ca2+ influx, mitochondrial reactive oxygen intermediates, and NF-kappaB activation. Infect Immun (2007) 1.02

A new self-emulsifying formulation of itraconazole with improved dissolution and oral absorption. J Control Release (2005) 1.01

Enhancement of solubility, dissolution and bioavailability of ibuprofen in solid dispersion systems. Chem Pharm Bull (Tokyo) (2008) 1.01

The effects of mixed MPEG-PLA/Pluronic copolymer micelles on the bioavailability and multidrug resistance of docetaxel. Biomaterials (2010) 1.00

Stability and cellular uptake of polymerized siRNA (poly-siRNA)/polyethylenimine (PEI) complexes for efficient gene silencing. J Control Release (2009) 1.00

Trials of clear aceclofenac-loaded soft capsules with accelerated oral absorption in human subjects. Int J Pharm (2005) 1.00

In vitro and in vivo transfection efficiency of a novel ultradeformable cationic liposome. Biomaterials (2004) 0.99

Hyaluronic acid-polyethyleneimine conjugate for target specific intracellular delivery of siRNA. Biopolymers (2008) 0.98

Enhanced rectal bioavailability of ibuprofen in rats by poloxamer 188 and menthol. Int J Pharm (2004) 0.97

Topical application of porcine placenta extract inhibits the progression of experimental contact hypersensitivity. J Ethnopharmacol (2010) 0.97

Helicobacter pylori infection activates NF-kappaB signaling pathway to induce iNOS and protect human gastric epithelial cells from apoptosis. Am J Physiol Gastrointest Liver Physiol (2003) 0.96

Novel cationic cholesterol derivative-based liposomes for serum-enhanced delivery of siRNA. Int J Pharm (2007) 0.95

Altered chemical and biological activities of all-trans retinoic acid incorporated in solid lipid nanoparticle powders. J Control Release (2004) 0.95

Effects of transcription factor activator protein-1 on interleukin-8 expression and enteritis in response to Clostridium difficile toxin A. J Mol Med (Berl) (2007) 0.95

The use of chitosan as a condensing agent to enhance emulsion-mediated gene transfer. Biomaterials (2005) 0.95

The use of PEGylated liposomes to prolong circulation lifetimes of tissue plasminogen activator. Biomaterials (2009) 0.94

Bacteroides fragilis enterotoxin induces cyclooxygenase-2 and fluid secretion in intestinal epithelial cells through NF-kappaB activation. Eur J Immunol (2006) 0.94

Development of docetaxel-loaded solid self-nanoemulsifying drug delivery system (SNEDDS) for enhanced chemotherapeutic effect. Int J Pharm (2013) 0.94

Safety and tumor tissue accumulation of pegylated graphene oxide nanosheets for co-delivery of anticancer drug and photosensitizer. Biomaterials (2013) 0.93

Preparation of ibuprofen-loaded liquid suppository using eutectic mixture system with menthol. Eur J Pharm Sci (2004) 0.93

Enhanced humoral and cellular immune responses after sublingual immunization against human papillomavirus 16 L1 protein with adjuvants. Vaccine (2010) 0.93

Tumor-homing glycol chitosan/polyethylenimine nanoparticles for the systemic delivery of siRNA in tumor-bearing mice. J Control Release (2010) 0.93

Synthesis and evaluation of Ketorolac ester prodrugs for transdermal delivery. J Pharm Sci (2003) 0.93

Preparation and evaluation of taste-masked donepezil hydrochloride orally disintegrating tablets. Biol Pharm Bull (2010) 0.92

Reduced food-effect and enhanced bioavailability of a self-microemulsifying formulation of itraconazole in healthy volunteers. Eur J Pharm Sci (2007) 0.91

Accelerated wound healing by smad3 antisense oligonucleotides-impregnated chitosan/alginate polyelectrolyte complex. Biomaterials (2008) 0.91

Bacteroides fragilis enterotoxin induces human beta-defensin-2 expression in intestinal epithelial cells via a mitogen-activated protein kinase/I kappaB kinase/NF-kappaB-dependent pathway. Infect Immun (2010) 0.91

Development of clindamycin-loaded wound dressing with polyvinyl alcohol and sodium alginate. Biol Pharm Bull (2008) 0.91

Comparison of solid self-microemulsifying drug delivery system (solid SMEDDS) prepared with hydrophilic and hydrophobic solid carrier. Int J Pharm (2011) 0.91

Trilysinoyl oleylamide-based cationic liposomes for systemic co-delivery of siRNA and an anticancer drug. J Control Release (2010) 0.91

Release behavior and photo-image of nifedipine tablet coated with high viscosity grade hydroxypropylmethylcellulose: effect of coating conditions. Int J Pharm (2004) 0.90

Phospholipid-based microemulsion formulation of all-trans-retinoic acid for parenteral administration. Int J Pharm (2004) 0.90

Simvastatin prevents oxygen and glucose deprivation/reoxygenation-induced death of cortical neurons by reducing the production and toxicity of 4-hydroxy-2E-nonenal. J Neurochem (2006) 0.89

In vivo imaging of tumor apoptosis using histone H1-targeting peptide. J Control Release (2010) 0.89

Physicochemical characterization of diclofenac sodium-loaded poloxamer gel as a rectal delivery system with fast absorption. Drug Dev Ind Pharm (2003) 0.89

Skin penetration and retention of L-ascorbic acid 2-phosphate using multilamellar vesicles. Arch Pharm Res (2008) 0.89

Enhanced mucosal and systemic immune responses following intravaginal immunization with human papillomavirus 16 L1 virus-like particle vaccine in thermosensitive mucoadhesive delivery systems. J Med Virol (2003) 0.89

Preparation and evaluation of fast dissolving ibuprofen-polyethylene glycol 6000 solid dispersions. Drug Deliv (2008) 0.89

Inhibitory effects of asiatic acid on 7,12-dimethylbenz[a]anthracene and 12-O-tetradecanoylphorbol 13-acetate-induced tumor promotion in mice. Biol Pharm Bull (2007) 0.88

Rheological characterization and in vivo evaluation of thermosensitive poloxamer-based hydrogel for intramuscular injection of piroxicam. Int J Pharm (2010) 0.88

Formulation and optimization of raloxifene-loaded solid lipid nanoparticles to enhance oral bioavailability. J Nanosci Nanotechnol (2014) 0.88

Ketorolac amide prodrugs for transdermal delivery: stability and in vitro rat skin permeation studies. Int J Pharm (2005) 0.88

Low molecular weight polyethylenimine for efficient transfection of human hematopoietic and umbilical cord blood-derived CD34+ cells. Biochim Biophys Acta (2005) 0.88

Effect of edge activators on the formation and transfection efficiency of ultradeformable liposomes. Biomaterials (2005) 0.88

Preparation and evaluation of raloxifene-loaded solid dispersion nanoparticle by spray-drying technique without an organic solvent. Int J Pharm (2013) 0.88