Published in J Control Release on July 17, 2009
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Systemic delivery of gemcitabine triphosphate via LCP nanoparticles for NSCLC and pancreatic cancer therapy. Biomaterials (2013) 0.99
An optical and microPET assessment of thermally-sensitive liposome biodistribution in the Met-1 tumor model: Importance of formulation. J Control Release (2009) 0.97
Disconnecting the yin and yang relation of epidermal growth factor receptor (EGFR)-mediated delivery: a fully synthetic, EGFR-targeted gene transfer system avoiding receptor activation. Hum Gene Ther (2011) 0.95
Gemcitabine-loaded liposomes: rationale, potentialities and future perspectives. Int J Nanomedicine (2012) 0.90
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In vitro and in vivo assessment of targeting lipid-based nanoparticles to the epidermal growth factor-receptor (EGFR) using a novel Heptameric ZEGFR domain. J Control Release (2011) 0.85
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A Novel Strategy to Improve the Therapeutic Efficacy of Gemcitabine for Non-Small Cell Lung Cancer by the Tumor-Penetrating Peptide iRGD. PLoS One (2015) 0.82
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Magnetic Nanoparticles Cross the Blood-Brain Barrier: When Physics Rises to a Challenge. Nanomaterials (Basel) (2015) 0.75
Cellular uptake mechanism and intracellular fate of hydrophobically modified glycol chitosan nanoparticles. J Control Release (2009) 1.81
siRNA conjugate delivery systems. Bioconjug Chem (2009) 1.69
In situ gelling stimuli-sensitive block copolymer hydrogels for drug delivery. J Control Release (2008) 1.67
Uvrag targeting by Mir125a and Mir351 modulates autophagy associated with Ewsr1 deficiency. Autophagy (2015) 1.42
Biodistribution and improved anticancer effect of NIK-siRNA in combination with 5-FU for hepatocellular carcinoma. Arch Pharm Res (2011) 1.39
Injectable biodegradable hydrogels. Macromol Biosci (2010) 1.24
Target-specific intracellular delivery of siRNA using degradable hyaluronic acid nanogels. J Control Release (2007) 1.20
Tumor-targeting peptide conjugated pH-responsive micelles as a potential drug carrier for cancer therapy. Bioconjug Chem (2010) 1.16
Prolonged antifungal effects of clotrimazole-containing mucoadhesive thermosensitive gels on vaginitis. J Control Release (2002) 1.15
Gas foamed open porous biodegradable polymeric microspheres. Biomaterials (2006) 1.14
Rat organic anion transporter 3 (rOAT3) is responsible for brain-to-blood efflux of homovanillic acid at the abluminal membrane of brain capillary endothelial cells. J Cereb Blood Flow Metab (2003) 1.10
Novel pH sensitive block copolymer micelles for solvent free drug loading. Macromol Biosci (2006) 1.08
Alterations in promoter usage and expression levels of insulin-like growth factor-II and H19 genes in cervical carcinoma exhibiting biallelic expression of IGF-II. Biochim Biophys Acta (2002) 1.06
Tumor specificity and therapeutic efficacy of photosensitizer-encapsulated glycol chitosan-based nanoparticles in tumor-bearing mice. Biomaterials (2009) 1.05
Accelerated cerebral ischemic injury by activated macrophages/microglia after lipopolysaccharide microinjection into rat corpus callosum. Glia (2005) 1.04
Differential expression and polarized secretion of CXC and CC chemokines by human intestinal epithelial cancer cell lines in response to Clostridium difficile toxin A. Microbiol Immunol (2002) 1.04
Tumoral acidic extracellular pH targeting of pH-responsive MPEG-poly(beta-amino ester) block copolymer micelles for cancer therapy. J Control Release (2007) 1.03
Vacuolating cytotoxin in Helicobacter pylori water-soluble proteins upregulates chemokine expression in human eosinophils via Ca2+ influx, mitochondrial reactive oxygen intermediates, and NF-kappaB activation. Infect Immun (2007) 1.02
Anti-inflammatory mechanism of ginsenoside Rh1 in lipopolysaccharide-stimulated microglia: critical role of the protein kinase A pathway and hemeoxygenase-1 expression. J Neurochem (2010) 1.02
CpG oligodeoxynucleotides induce IL-8 expression in CD34+ cells via mitogen-activated protein kinase-dependent and NF-kappaB-independent pathways. Int Immunol (2005) 1.02
Tumoral acidic pH-responsive MPEG-poly(beta-amino ester) polymeric micelles for cancer targeting therapy. J Control Release (2010) 1.01
Macroporous poly(L-lactide) scaffold 1. Preparation of a macroporous scaffold by liquid--liquid phase separation of a PLLA--dioxane--water system. J Biomed Mater Res (2002) 1.00
Stability and cellular uptake of polymerized siRNA (poly-siRNA)/polyethylenimine (PEI) complexes for efficient gene silencing. J Control Release (2009) 1.00
Trials of clear aceclofenac-loaded soft capsules with accelerated oral absorption in human subjects. Int J Pharm (2005) 1.00
Public attitudes toward cancer and cancer patients: a national survey in Korea. Psychooncology (2012) 0.99
The brain-to-blood efflux transport of taurine and changes in the blood-brain barrier transport system by tumor necrosis factor-alpha. Brain Res (2004) 0.99
Hyaluronic acid-polyethyleneimine conjugate for target specific intracellular delivery of siRNA. Biopolymers (2008) 0.98
Immobilization of cell adhesive RGD peptide onto the surface of highly porous biodegradable polymer scaffolds fabricated by a gas foaming/salt leaching method. Biomaterials (2004) 0.98
In vivo tumor diagnosis and photodynamic therapy via tumoral pH-responsive polymeric micelles. Chem Commun (Camb) (2010) 0.98
Topical application of porcine placenta extract inhibits the progression of experimental contact hypersensitivity. J Ethnopharmacol (2010) 0.97
Helicobacter pylori infection activates NF-kappaB signaling pathway to induce iNOS and protect human gastric epithelial cells from apoptosis. Am J Physiol Gastrointest Liver Physiol (2003) 0.96
Novel cationic cholesterol derivative-based liposomes for serum-enhanced delivery of siRNA. Int J Pharm (2007) 0.95
Effects of transcription factor activator protein-1 on interleukin-8 expression and enteritis in response to Clostridium difficile toxin A. J Mol Med (Berl) (2007) 0.95
Bacteroides fragilis enterotoxin induces cyclooxygenase-2 and fluid secretion in intestinal epithelial cells through NF-kappaB activation. Eur J Immunol (2006) 0.94
Development of docetaxel-loaded solid self-nanoemulsifying drug delivery system (SNEDDS) for enhanced chemotherapeutic effect. Int J Pharm (2013) 0.94
Upregulation of NAD(P)H:quinone oxidoreductase by radiation potentiates the effect of bioreductive beta-lapachone on cancer cells. Neoplasia (2007) 0.94
Preparation of ibuprofen-loaded liquid suppository using eutectic mixture system with menthol. Eur J Pharm Sci (2004) 0.93
Tumor-homing glycol chitosan/polyethylenimine nanoparticles for the systemic delivery of siRNA in tumor-bearing mice. J Control Release (2010) 0.93
Enhanced humoral and cellular immune responses after sublingual immunization against human papillomavirus 16 L1 protein with adjuvants. Vaccine (2010) 0.93
Safety and tumor tissue accumulation of pegylated graphene oxide nanosheets for co-delivery of anticancer drug and photosensitizer. Biomaterials (2013) 0.93
Novel injectable pH and temperature sensitive block copolymer hydrogel. Biomacromolecules (2005) 0.92
Enhanced antitumor activity of vitamin C via p53 in cancer cells. Free Radic Biol Med (2012) 0.91
pH-responsive polymeric micelle based on PEG-poly(β-amino ester)/(amido amine) as intelligent vehicle for magnetic resonance imaging in detection of cerebral ischemic area. J Control Release (2010) 0.91
Trilysinoyl oleylamide-based cationic liposomes for systemic co-delivery of siRNA and an anticancer drug. J Control Release (2010) 0.91
Bacteroides fragilis enterotoxin induces human beta-defensin-2 expression in intestinal epithelial cells via a mitogen-activated protein kinase/I kappaB kinase/NF-kappaB-dependent pathway. Infect Immun (2010) 0.91
Environmental pH-sensitive polymeric micelles for cancer diagnosis and targeted therapy. J Control Release (2012) 0.91
The fatty acid conjugated exendin-4 analogs for type 2 antidiabetic therapeutics. J Control Release (2010) 0.90
Effect of sodium chloride on the release, absorption and safety of diclofenac sodium delivered by poloxamer gel. Int J Pharm (2003) 0.90
Simvastatin prevents oxygen and glucose deprivation/reoxygenation-induced death of cortical neurons by reducing the production and toxicity of 4-hydroxy-2E-nonenal. J Neurochem (2006) 0.89
In vivo imaging of tumor apoptosis using histone H1-targeting peptide. J Control Release (2010) 0.89
β-lapachone significantly increases the effect of ionizing radiation to cause mitochondrial apoptosis via JNK activation in cancer cells. PLoS One (2011) 0.89
Novel histone deacetylase inhibitor CG200745 induces clonogenic cell death by modulating acetylation of p53 in cancer cells. Invest New Drugs (2010) 0.89
Thermal and mechanical characteristics of poly(L-lactic acid) nanocomposite scaffold. Biomaterials (2003) 0.89
Enhanced mucosal and systemic immune responses following intravaginal immunization with human papillomavirus 16 L1 virus-like particle vaccine in thermosensitive mucoadhesive delivery systems. J Med Virol (2003) 0.89
Magnetite-nanoparticle-encapsulated pH-responsive polymeric micelle as an MRI probe for detecting acidic pathologic areas. Small (2010) 0.89
Changes in the bispectral index and cerebral oxygen saturation during neuroendovascular intervention under general anesthesia. Korean J Anesthesiol (2012) 0.88
Antifibrotic effect of MMP13-encoding plasmid DNA delivered using polyethylenimine shielded with hyaluronic acid. Mol Ther (2010) 0.88
Effect of edge activators on the formation and transfection efficiency of ultradeformable liposomes. Biomaterials (2005) 0.88
Low molecular weight polyethylenimine for efficient transfection of human hematopoietic and umbilical cord blood-derived CD34+ cells. Biochim Biophys Acta (2005) 0.88
Controlled protein release from electrospun biodegradable fiber mesh composed of poly(epsilon-caprolactone) and poly(ethylene oxide). Int J Pharm (2007) 0.88
Perception, attitudes, preparedness and experience of chemotherapy-induced alopecia among breast cancer patients: a qualitative study. Asian Pac J Cancer Prev (2012) 0.87
Enhanced intrapulmonary delivery of anticancer siRNA for lung cancer therapy using cationic ethylphosphocholine-based nanolipoplexes. Mol Ther (2013) 0.87
HAUSP, a deubiquitinating enzyme for p53, is polyubiquitinated, polyneddylated, and dimerized. FEBS Lett (2005) 0.87
Sulfonamide-based pH- and temperature-sensitive biodegradable block copolymer hydrogels. Biomacromolecules (2006) 0.87
Plasmid vectors harboring cellular promoters can induce prolonged gene expression in hematopoietic and mesenchymal progenitor cells. Biochem Biophys Res Commun (2005) 0.86
Injectable in situ-forming pH/thermo-sensitive hydrogel for bone tissue engineering. Tissue Eng Part A (2009) 0.86
Biodegradable and pH-sensitive polymersome with tuning permeable membrane for drug delivery carrier. Chem Commun (Camb) (2010) 0.86
Anti-inflammatory activity of Taraxacum officinale. J Ethnopharmacol (2007) 0.86
Immunogenicity of bivalent human papillomavirus DNA vaccine using human endogenous retrovirus envelope-coated baculoviral vectors in mice and pigs. PLoS One (2012) 0.86
pH-Sensitive nanoflash for tumoral acidic pH imaging in live animals. Small (2010) 0.86
A novel peptide probe for imaging and targeted delivery of liposomal doxorubicin to lung tumor. Mol Pharm (2011) 0.86
Cholesteryl hyaluronic acid-coated, reduced graphene oxide nanosheets for anti-cancer drug delivery. Biomaterials (2013) 0.86
pH- and temperature-sensitive, injectable, biodegradable block copolymer hydrogels as carriers for paclitaxel. Int J Pharm (2006) 0.86
In situ gelling and mucoadhesive polymer vehicles for controlled intranasal delivery of plasmid DNA. J Biomed Mater Res (2002) 0.86
Ciclopirox protects mitochondria from hydrogen peroxide toxicity. Br J Pharmacol (2005) 0.86
Enhancement of DC vaccine potency by activating the PI3K/AKT pathway with a small interfering RNA targeting PTEN. Immunol Lett (2010) 0.86
Enhanced inhibition of murine tumor and human breast tumor xenografts using targeted delivery of an antibody-endostatin fusion protein. Mol Cancer Ther (2005) 0.86
Cationic drug-derived nanoparticles for multifunctional delivery of anticancer siRNA. Biomaterials (2011) 0.86
Radiation therapy is a treatment to be considered for recurrent epithelial ovarian cancer after chemotherapy. Tumori (2011) 0.85
Enhanced brain targeting efficiency of intranasally administered plasmid DNA: an alternative route for brain gene therapy. J Mol Med (Berl) (2006) 0.85
Cationic solid lipid nanoparticles for co-delivery of paclitaxel and siRNA. Eur J Pharm Biopharm (2011) 0.85
Nitric oxide production by the vacuolar-type (H+)-ATPase inhibitors bafilomycin A1 and concanamycin A and its possible role in apoptosis in RAW 264.7 cells. J Pharmacol Exp Ther (2006) 0.85
Oncogenic function of p34SEI-1 via NEDD4‑1‑mediated PTEN ubiquitination/degradation and activation of the PI3K/AKT pathway. Int J Oncol (2013) 0.85
Controlled release of insulin from pH/temperature-sensitive injectable pentablock copolymer hydrogel. J Control Release (2009) 0.85
Development of a novel viral DNA vaccine against human papillomavirus: AcHERV-HP16L1. Vaccine (2009) 0.85
In vivo delivery of small interfering RNA targeting brain capillary endothelial cells. Biochem Biophys Res Commun (2005) 0.84
Reduction of L-type amino acid transporter 1 mRNA expression in brain capillaries in a mouse model of Parkinson's disease. Biol Pharm Bull (2010) 0.84
The synergistic therapeutic effect of cisplatin with Human papillomavirus E6/E7 short interfering RNA on cervical cancer cell lines in vitro and in vivo. Int J Cancer (2011) 0.84
Function and regulation of taurine transport at the inner blood-retinal barrier. Microvasc Res (2006) 0.84
Pegylated poly-l-arginine derivatives of chitosan for effective delivery of siRNA. J Control Release (2010) 0.84
Organic anion transporter 3 is involved in the brain-to-blood efflux transport of thiopurine nucleobase analogs. J Neurochem (2004) 0.84
Biodistribution and tissue expression kinetics of plasmid DNA complexed with polyethylenimines of different molecular weight and structure. J Control Release (2006) 0.84