Published in Endocrinology on June 26, 2003
Longitudinal noninvasive PET-based beta cell mass estimates in a spontaneous diabetes rat model. J Clin Invest (2006) 2.08
Visualizing pancreatic beta-cell mass with [11C]DTBZ. Nucl Med Biol (2006) 1.67
Hypothalamic POMC Deficiency Improves Glucose Tolerance Despite Insulin Resistance by Increasing Glycosuria. Diabetes (2015) 1.45
Simultaneous silencing of Npy and Dbh expression in hindbrain A1/C1 catecholamine cells suppresses glucoprivic feeding. J Neurosci (2009) 0.96
Regulatory polymorphisms in human DBH affect peripheral gene expression and sympathetic activity. Circ Res (2014) 0.84
Blocking of beta-2 adrenergic receptors hastens recovery from hypoglycemia-associated social withdrawal. Psychoneuroendocrinology (2008) 0.78
Hyperinsulinemia and Insulin Resistance in Dopamine β-Hydroxylase Deficiency. J Clin Endocrinol Metab (2016) 0.75
Central Congenital Hypoventilation Syndrome associated with hypoglycemia and seizure. Respir Med Case Rep (2016) 0.75
A robust and high-throughput Cre reporting and characterization system for the whole mouse brain. Nat Neurosci (2009) 21.94
NPY/AgRP neurons are essential for feeding in adult mice but can be ablated in neonates. Science (2005) 6.55
Loss of GABAergic signaling by AgRP neurons to the parabrachial nucleus leads to starvation. Cell (2009) 3.94
mTOR inhibition alleviates mitochondrial disease in a mouse model of Leigh syndrome. Science (2013) 3.41
Disruption of NMDAR-dependent burst firing by dopamine neurons provides selective assessment of phasic dopamine-dependent behavior. Proc Natl Acad Sci U S A (2009) 3.15
Parkin-mediated K63-linked polyubiquitination targets misfolded DJ-1 to aggresomes via binding to HDAC6. J Cell Biol (2007) 3.13
Vesicular glutamate transport promotes dopamine storage and glutamate corelease in vivo. Neuron (2010) 2.75
Mice with mitochondrial complex I deficiency develop a fatal encephalomyopathy. Cell Metab (2008) 2.72
Role of NMDA receptors in dopamine neurons for plasticity and addictive behaviors. Neuron (2008) 2.41
Parkin-deficient mice are not a robust model of parkinsonism. Proc Natl Acad Sci U S A (2005) 2.27
Novel monoclonal antibodies demonstrate biochemical variation of brain parkin with age. J Biol Chem (2003) 2.26
GAD67-mediated GABA synthesis and signaling regulate inhibitory synaptic innervation in the visual cortex. Neuron (2007) 2.23
Deciphering a neuronal circuit that mediates appetite. Nature (2012) 2.21
Genetic identification of a neural circuit that suppresses appetite. Nature (2013) 2.18
Distinguishing whether dopamine regulates liking, wanting, and/or learning about rewards. Behav Neurosci (2005) 2.02
Activation of the kappa opioid receptor in the dorsal raphe nucleus mediates the aversive effects of stress and reinstates drug seeking. Proc Natl Acad Sci U S A (2009) 1.88
Cre recombinase-mediated restoration of nigrostriatal dopamine in dopamine-deficient mice reverses hypophagia and bradykinesia. Proc Natl Acad Sci U S A (2006) 1.85
Selective p38α MAPK deletion in serotonergic neurons produces stress resilience in models of depression and addiction. Neuron (2011) 1.83
Reward without dopamine. J Neurosci (2003) 1.80
Contribution by synaptic zinc to the gender-disparate plaque formation in human Swedish mutant APP transgenic mice. Proc Natl Acad Sci U S A (2002) 1.68
Dopamine supersensitivity correlates with D2High states, implying many paths to psychosis. Proc Natl Acad Sci U S A (2005) 1.67
Morphine reward in dopamine-deficient mice. Nature (2005) 1.66
Complex I deficiency due to loss of Ndufs4 in the brain results in progressive encephalopathy resembling Leigh syndrome. Proc Natl Acad Sci U S A (2010) 1.62
NPY/AgRP neurons are not essential for feeding responses to glucoprivation. Peptides (2006) 1.61
Mitochondrial complex I inhibition is not required for dopaminergic neuron death induced by rotenone, MPP+, or paraquat. Proc Natl Acad Sci U S A (2008) 1.61
Multiple pathways involved in the biosynthesis of anandamide. Neuropharmacology (2007) 1.59
Cocaine-conditioned place preference by dopamine-deficient mice is mediated by serotonin. J Neurosci (2007) 1.57
Dopamine modulates release from corticostriatal terminals. J Neurosci (2004) 1.54
Redundancy in Kiss1 expression safeguards reproduction in the mouse. Endocrinology (2013) 1.49
Firing properties of dopamine neurons in freely moving dopamine-deficient mice: effects of dopamine receptor activation and anesthesia. Proc Natl Acad Sci U S A (2004) 1.48
Neuropeptide Y is an essential in vivo developmental regulator of cardiac ICa,L. Circ Res (2003) 1.47
Activation of dopamine neurons is critical for aversive conditioning and prevention of generalized anxiety. Nat Neurosci (2011) 1.46
Overexpression of c-Myc in beta-cells of transgenic mice causes proliferation and apoptosis, downregulation of insulin gene expression, and diabetes. Diabetes (2002) 1.43
Retinal dopamine mediates multiple dimensions of light-adapted vision. J Neurosci (2012) 1.42
Deletion of GAD67 in dopamine receptor-1 expressing cells causes specific motor deficits. Genesis (2008) 1.42
Dopamine is necessary for cue-dependent fear conditioning. J Neurosci (2009) 1.38
Role of noradrenergic signaling by the nucleus tractus solitarius in mediating opiate reward. Science (2006) 1.35
Starvation after AgRP neuron ablation is independent of melanocortin signaling. Proc Natl Acad Sci U S A (2008) 1.32
Loss of mitochondrial complex I activity potentiates dopamine neuron death induced by microtubule dysfunction in a Parkinson's disease model. J Cell Biol (2011) 1.28
Requirement of dopamine signaling in the amygdala and striatum for learning and maintenance of a conditioned avoidance response. Learn Mem (2011) 1.27
Mice with chronic norepinephrine deficiency resemble amphetamine-sensitized animals. Proc Natl Acad Sci U S A (2002) 1.27
Absence of NMDA receptors in dopamine neurons attenuates dopamine release but not conditioned approach during Pavlovian conditioning. Proc Natl Acad Sci U S A (2010) 1.26
Lack of GPR88 enhances medium spiny neuron activity and alters motor- and cue-dependent behaviors. Nat Neurosci (2012) 1.25
Expression of mutant NMDA receptors in dopamine D1 receptor-containing cells prevents cocaine sensitization and decreases cocaine preference. J Neurosci (2005) 1.25
Zinc released from metallothionein-iii may contribute to hippocampal CA1 and thalamic neuronal death following acute brain injury. Exp Neurol (2003) 1.22
Dopamine is not required for the hyperlocomotor response to NMDA receptor antagonists. Neuropsychopharmacology (2005) 1.21
Molecular properties of Kiss1 neurons in the arcuate nucleus of the mouse. Endocrinology (2011) 1.21
Zinc transporter ZnT-3 regulates presynaptic Erk1/2 signaling and hippocampus-dependent memory. Proc Natl Acad Sci U S A (2011) 1.16
Dysregulation of dopamine signaling in the dorsal striatum inhibits feeding. Brain Res (2005) 1.16
Neuronal zinc exchange with the blood vessel wall promotes cerebral amyloid angiopathy in an animal model of Alzheimer's disease. J Neurosci (2004) 1.15
The origins of oncomice: a history of the first transgenic mice genetically engineered to develop cancer. Genes Dev (2007) 1.15
Dbh(-/-) mice are hypotensive, have altered circadian rhythms, and have abnormal responses to dieting and stress. Am J Physiol Regul Integr Comp Physiol (2003) 1.14
GABAergic signaling by AgRP neurons prevents anorexia via a melanocortin-independent mechanism. Eur J Pharmacol (2011) 1.14
Ablation of neurons expressing agouti-related protein activates fos and gliosis in postsynaptic target regions. J Neurosci (2008) 1.13
Restriction of dopamine signaling to the dorsolateral striatum is sufficient for many cognitive behaviors. Proc Natl Acad Sci U S A (2009) 1.13
Hair cell replacement in adult mouse utricles after targeted ablation of hair cells with diphtheria toxin. J Neurosci (2012) 1.13
Mitochondrion-derived reactive oxygen species lead to enhanced amyloid beta formation. Antioxid Redox Signal (2012) 1.12
Restricting dopaminergic signaling to either dorsolateral or medial striatum facilitates cognition. J Neurosci (2010) 1.11
Transient activation of specific neurons in mice by selective expression of the capsaicin receptor. Nat Commun (2012) 1.10
Dopamine controls the firing pattern of dopamine neurons via a network feedback mechanism. Proc Natl Acad Sci U S A (2003) 1.10
Ablation of neurons expressing agouti-related protein, but not melanin concentrating hormone, in leptin-deficient mice restores metabolic functions and fertility. Proc Natl Acad Sci U S A (2012) 1.09
Viral restoration of dopamine signaling to the dorsal striatum restores instrumental conditioning to dopamine-deficient mice. Psychopharmacology (Berl) (2006) 1.06
Balanced NMDA receptor activity in dopamine D1 receptor (D1R)- and D2R-expressing medium spiny neurons is required for amphetamine sensitization. Proc Natl Acad Sci U S A (2011) 1.06
Fatal breathing dysfunction in a mouse model of Leigh syndrome. J Clin Invest (2012) 1.04
Viral restoration of dopamine to the nucleus accumbens is sufficient to induce a locomotor response to amphetamine. Brain Res (2003) 1.04
Norepinephrine-deficient mice exhibit normal sleep-wake states but have shorter sleep latency after mild stress and low doses of amphetamine. Sleep (2003) 1.03
Altered anesthetic sensitivity of mice lacking Ndufs4, a subunit of mitochondrial complex I. PLoS One (2012) 1.02
Contributions of striatal dopamine signaling to the modulation of cognitive flexibility. Biol Psychiatry (2010) 1.01
Modulation of neuropeptide Y expression in adult mice does not affect feeding. Proc Natl Acad Sci U S A (2005) 1.01
Parkin-deficient mice are not more sensitive to 6-hydroxydopamine or methamphetamine neurotoxicity. BMC Neurosci (2005) 1.01
The NK1 receptor mediates both the hyperalgesia and the resistance to morphine in mice lacking noradrenaline. Proc Natl Acad Sci U S A (2002) 1.01
Regulation of norepinephrine transporter abundance by catecholamines and desipramine in vivo. Brain Res (2002) 1.00
Mouse zinc transporter 1 gene provides an essential function during early embryonic development. Genesis (2004) 1.00
The contribution of NMDA receptor signaling in the corticobasal ganglia reward network to appetitive Pavlovian learning. J Neurosci (2011) 0.99
Induction of metallothionein I by phenolic antioxidants requires metal-activated transcription factor 1 (MTF-1) and zinc. Biochem J (2004) 0.98
Neuropeptide Y protects against methamphetamine-induced neuronal apoptosis in the mouse striatum. J Neurosci (2005) 0.98
Role of agouti-related protein-expressing neurons in lactation. Endocrinology (2007) 0.98
Ablation of neurons expressing melanin-concentrating hormone (MCH) in adult mice improves glucose tolerance independent of MCH signaling. J Neurosci (2013) 0.97
Local dopamine production in the dorsal striatum restores goal-directed behavior in dopamine-deficient mice. Behav Neurosci (2006) 0.97
The role of dopamine in learning, memory, and performance of a water escape task. Behav Brain Res (2004) 0.97
Estrogen decreases zinc transporter 3 expression and synaptic vesicle zinc levels in mouse brain. J Biol Chem (2003) 0.95
Attenuating GABA(A) receptor signaling in dopamine neurons selectively enhances reward learning and alters risk preference in mice. J Neurosci (2011) 0.95
Adenosine receptor blockade reverses hypophagia and enhances locomotor activity of dopamine-deficient mice. Proc Natl Acad Sci U S A (2003) 0.94
Altered sleep latency and arousal regulation in mice lacking norepinephrine. Pharmacol Biochem Behav (2004) 0.94
Neuropeptide Y is required for hyperphagic feeding in response to neuroglucopenia. Endocrinology (2004) 0.94
Genetic activation of ERK5 MAP kinase enhances adult neurogenesis and extends hippocampus-dependent long-term memory. J Neurosci (2014) 0.94
Dopamine-dependent desensitization of dopaminergic signaling in the developing mouse striatum. J Neurosci (2002) 0.93
Long-term memory for pavlovian fear conditioning requires dopamine in the nucleus accumbens and basolateral amygdala. PLoS One (2010) 0.93
NR2B subunit of the NMDA glutamate receptor regulates appetite in the parabrachial nucleus. Proc Natl Acad Sci U S A (2013) 0.91
Attenuation of diabetic hyperphagia in neuropeptide Y--deficient mice. Diabetes (2002) 0.91
Clioquinol and docosahexaenoic acid act synergistically to kill tumor cells. Mol Cancer Ther (2006) 0.90
Dysregulation of striatal dopamine signaling by amphetamine inhibits feeding by hungry mice. Neuron (2004) 0.89
A behavioral genetics approach to understanding D1 receptor involvement in phasic dopamine signaling. Mol Cell Neurosci (2010) 0.88
Endogenous neurotensin attenuates dopamine-dependent locomotion and stereotypy. Brain Res (2004) 0.87
Chronic neuropeptide Y infusion into the lateral ventricle induces sustained feeding and obesity in mice lacking either Npy1r or Npy5r expression. Endocrinology (2003) 0.87
The neuropeptide Y Y1 receptor regulates leptin-mediated control of energy homeostasis and reproductive functions. FASEB J (2002) 0.87
A role for dopamine in feeding responses produced by orexigenic agents. Brain Res (2004) 0.86
Dopamine depletion does not protect against acute 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine toxicity in vivo. J Neurosci (2005) 0.86
Attenuated feeding responses to circadian and palatability cues in mice lacking neuropeptide Y. Peptides (2005) 0.85
Restoration of dopamine signaling to the dorsal striatum is sufficient for aspects of active maternal behavior in female mice. Endocrinology (2013) 0.85