Published in Endocrinology on August 28, 2003
Management of Hyperglycemic Patients in Emergency Medicine Department | NCT04665128
How does blood glucose control with insulin save lives in intensive care? J Clin Invest (2004) 2.65
Intensive insulin therapy protects the endothelium of critically ill patients. J Clin Invest (2005) 2.11
Hyperinsulinemia predicts survival in a hyperglycemic mouse model of critical illness. Crit Care Med (2009) 1.41
Metabolic and nutritional support of critically ill patients: consensus and controversies. Crit Care (2015) 1.28
Diabetes, insulin, and development of acute lung injury. Crit Care Med (2009) 1.26
Hyperosmotic stress enhances cytokine production and decreases phagocytosis in vitro. Crit Care (2008) 1.18
Organ failure and tight glycemic control in the SPRINT study. Crit Care (2010) 1.12
Insulin therapy for the management of hyperglycemia in hospitalized patients. Endocrinol Metab Clin North Am (2012) 1.04
Hyperglycemia in critical illness: a review. J Diabetes Sci Technol (2009) 1.04
Metabolic changes after polytrauma: an imperative for early nutritional support. World J Emerg Surg (2006) 1.02
Glycemic control in non-diabetic critically ill patients. Best Pract Res Clin Endocrinol Metab (2011) 1.00
New insights into insulin: The anti-inflammatory effect and its clinical relevance. World J Diabetes (2014) 0.94
Implementing glucose control in intensive care: a multicenter trial using statistical process control. Intensive Care Med (2010) 0.91
Short-term hyperglycemia in surgical patients and a study of related cellular mechanisms. Ann Surg (2006) 0.89
Moderate glucose control is associated with increased mortality compared with tight glucose control in critically ill patients without diabetes. Chest (2013) 0.87
Is there a relationship between admission blood glucose level following acute poisoning and clinical outcome? Arch Med Sci (2011) 0.87
Sex disparities in effects of cystic fibrosis-related diabetes on clinical outcomes: a matched study. Can Respir J (2008) 0.85
Topical application of naltrexone facilitates reepithelialization of the cornea in diabetic rabbits. Brain Res Bull (2009) 0.85
Stress hyperglycemia, insulin treatment, and innate immune cells. Int J Endocrinol (2014) 0.85
Intraoperative glycemic control procedures and the use of an artificial pancreas. World J Gastroenterol (2009) 0.84
What do we need beyond hemoglobin A1c to get the complete picture of glycemia in people with diabetes? Int J Med Sci (2012) 0.82
Glutamine metabolism drives succinate accumulation in plasma and the lung during hemorrhagic shock. J Trauma Acute Care Surg (2016) 0.81
Effects of substitution and high-dose thyroid hormone therapy on deiodination, sulfoconjugation, and tissue thyroid hormone levels in prolonged critically ill rabbits. Endocrinology (2008) 0.79
The benefits of tight glycemic control in critical illness: Sweeter than assumed? Indian J Crit Care Med (2014) 0.78
Intensive versus conventional insulin therapy in type 2 diabetes patients undergoing D2 gastrectomy for gastric cancer: a randomized controlled trial. World J Surg (2011) 0.77
Glucose control in the ICU: is there a time for more ambitious targets again? J Diabetes Sci Technol (2014) 0.76
Intensive insulin therapy to maintain normoglycemia after cardiac surgery. HSR Proc Intensive Care Cardiovasc Anesth (2011) 0.76
Untangling glycaemia and mortality in critical care. Crit Care (2017) 0.75
Influence of a strict glucose protocol on serum potassium and glucose concentrations and their association with mortality in intensive care patients. Crit Care (2015) 0.75
Hyperglycaemia in critically ill patients: the immune system's sweet tooth. Crit Care (2017) 0.75
Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy (2012) 20.08
Early versus late parenteral nutrition in critically ill adults. N Engl J Med (2011) 12.10
Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes. N Engl J Med (2005) 10.16
Intensive insulin therapy for patients in paediatric intensive care: a prospective, randomised controlled study. Lancet (2009) 6.44
Reduced cortisol metabolism during critical illness. N Engl J Med (2013) 6.01
Vitamin D and human health: lessons from vitamin D receptor null mice. Endocr Rev (2008) 5.28
Vitamin D deficiency is highly prevalent in COPD and correlates with variants in the vitamin D-binding gene. Thorax (2009) 4.86
ESPEN Guidelines on Parenteral Nutrition: intensive care. Clin Nutr (2009) 4.11
Serum potassium levels and mortality in acute myocardial infarction. JAMA (2012) 4.09
Nutrition in the acute phase of critical illness. N Engl J Med (2014) 4.02
Management of hyperglycemia in hospitalized patients in non-critical care setting: an endocrine society clinical practice guideline. J Clin Endocrinol Metab (2012) 4.02
High doses of vitamin D to reduce exacerbations in chronic obstructive pulmonary disease: a randomized trial. Ann Intern Med (2012) 3.99
Tight blood glucose control with insulin in the ICU: facts and controversies. Chest (2007) 3.79
Interleukin-17 orchestrates the granulocyte influx into airways after allergen inhalation in a mouse model of allergic asthma. Am J Respir Cell Mol Biol (2003) 3.60
Immunoregulation by 1,25-dihydroxyvitamin D3: basic concepts. J Steroid Biochem Mol Biol (2005) 3.44
Vitamin D: modulator of the immune system. Curr Opin Pharmacol (2010) 3.31
Neurocognitive development of children 4 years after critical illness and treatment with tight glucose control: a randomized controlled trial. JAMA (2012) 3.16
Dynamic characteristics of blood glucose time series during the course of critical illness: effects of intensive insulin therapy and relative association with mortality. Crit Care Med (2010) 3.16
Concern Guidelines for pre-operative cardiac risk assessment and perioperative cardiac management in non-cardiac surgery. Eur Heart J (2009) 3.14
Initiation and execution of lipotoxic ER stress in pancreatic beta-cells. J Cell Sci (2008) 2.99
Insulin degludec versus insulin glargine in insulin-naive patients with type 2 diabetes: a 1-year, randomized, treat-to-target trial (BEGIN Once Long). Diabetes Care (2012) 2.89
Impact of early parenteral nutrition on muscle and adipose tissue compartments during critical illness. Crit Care Med (2013) 2.81
Acute outcomes and 1-year mortality of intensive care unit-acquired weakness. A cohort study and propensity-matched analysis. Am J Respir Crit Care Med (2014) 2.68
Amino acid concentrations in critically ill children following cardiac surgery*. Pediatr Crit Care Med (2014) 2.65
A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death. EMBO J (2012) 2.45
Leaf mitochondria modulate whole cell redox homeostasis, set antioxidant capacity, and determine stress resistance through altered signaling and diurnal regulation. Plant Cell (2003) 2.22
Impact of intensive insulin therapy on neuromuscular complications and ventilator dependency in the medical intensive care unit. Am J Respir Crit Care Med (2006) 2.22
Sexual dysfunction in women with type 1 diabetes: a controlled study. Diabetes Care (2002) 2.20
Cytomegalovirus serostatus and outcome in nonimmunocompromised critically ill patients. Crit Care Med (2012) 2.14
Intensive insulin therapy protects the endothelium of critically ill patients. J Clin Invest (2005) 2.11
Polymorphisms in innate immunity genes predispose to bacteremia and death in the medical intensive care unit. Crit Care Med (2009) 2.10
Pressure autoregulation monitoring and cerebral perfusion pressure target recommendation in patients with severe traumatic brain injury based on minute-by-minute monitoring data. J Neurosurg (2014) 2.04
Intensive insulin therapy exerts antiinflammatory effects in critically ill patients and counteracts the adverse effect of low mannose-binding lectin levels. J Clin Endocrinol Metab (2003) 1.93
Monocytes from type 2 diabetic patients have a pro-inflammatory profile. 1,25-Dihydroxyvitamin D(3) works as anti-inflammatory. Diabetes Res Clin Pract (2006) 1.84
Reversal of autoimmune diabetes by restoration of antigen-specific tolerance using genetically modified Lactococcus lactis in mice. J Clin Invest (2012) 1.84
Prevalence and predictors of sexual dysfunction in patients with type 1 diabetes. Diabetes Care (2003) 1.82
Insufficient autophagy contributes to mitochondrial dysfunction, organ failure, and adverse outcome in an animal model of critical illness. Crit Care Med (2013) 1.78
Protection of hepatocyte mitochondrial ultrastructure and function by strict blood glucose control with insulin in critically ill patients. Lancet (2005) 1.78
Vitamin D: a pleiotropic hormone. Kidney Int (2010) 1.76
Clinical review: Consensus recommendations on measurement of blood glucose and reporting glycemic control in critically ill adults. Crit Care (2013) 1.72
Vitamin D and cancer. J Steroid Biochem Mol Biol (2006) 1.72
Clinical review: Critical illness polyneuropathy and myopathy. Crit Care (2008) 1.69
Tight blood glucose control is renoprotective in critically ill patients. J Am Soc Nephrol (2008) 1.67
Cellular islet autoimmunity associates with clinical outcome of islet cell transplantation. PLoS One (2008) 1.67
Vitamin D beyond bones in chronic obstructive pulmonary disease: time to act. Am J Respir Crit Care Med (2009) 1.63
Hypogonadism, quadriceps weakness, and exercise intolerance in chronic obstructive pulmonary disease. Am J Respir Crit Care Med (2005) 1.61
Correlation between beta cell mass and glycemic control in type 1 diabetic recipients of islet cell graft. Proc Natl Acad Sci U S A (2006) 1.60
Cortisol response to critical illness: effect of intensive insulin therapy. J Clin Endocrinol Metab (2006) 1.60
Tight glycemic control protects the myocardium and reduces inflammation in neonatal heart surgery. Ann Thorac Surg (2010) 1.59
American College of Endocrinology position statement on inpatient diabetes and metabolic control. Endocr Pract (2004) 1.59
Novel methods to predict increased intracranial pressure during intensive care and long-term neurologic outcome after traumatic brain injury: development and validation in a multicenter dataset. Crit Care Med (2013) 1.58
Modulation of asymmetric dimethylarginine in critically ill patients receiving intensive insulin treatment: a possible explanation of reduced morbidity and mortality? Crit Care Med (2005) 1.58
Muscle atrophy and preferential loss of myosin in prolonged critically ill patients. Crit Care Med (2012) 1.57
Association between elevated blood glucose and outcome in acute heart failure: results from an international observational cohort. J Am Coll Cardiol (2013) 1.55
ROS-induced autophagy in cancer cells assists in evasion from determinants of immunogenic cell death. Autophagy (2013) 1.55
Vitamin D and diabetes. Endocrinol Metab Clin North Am (2010) 1.52
Reducing mortality in sepsis: new directions. Crit Care (2002) 1.52
Toll-like receptor 3 and STAT-1 contribute to double-stranded RNA+ interferon-gamma-induced apoptosis in primary pancreatic beta-cells. J Biol Chem (2005) 1.50
Reduced activation and increased inactivation of thyroid hormone in tissues of critically ill patients. J Clin Endocrinol Metab (2003) 1.50
Regulation of the somatotropic axis by intensive insulin therapy during protracted critical illness. J Clin Endocrinol Metab (2004) 1.50
STAT1 is a master regulator of pancreatic {beta}-cell apoptosis and islet inflammation. J Biol Chem (2010) 1.49
Effect of insulin therapy on coagulation and fibrinolysis in medical intensive care patients. Crit Care Med (2008) 1.49
Critical illness-related corticosteroid insufficiency in patients with cirrhosis and variceal bleeding. Clin Gastroenterol Hepatol (2011) 1.49
American College of Endocrinology position statement on inpatient diabetes and metabolic control. Endocr Pract (2004) 1.47
Visualizing the pressure and time burden of intracranial hypertension in adult and paediatric traumatic brain injury. Intensive Care Med (2015) 1.44
Neuropathological Correlates of Hyperglycemia During Prolonged Polymicrobial Sepsis in Mice. Shock (2015) 1.43
Optimal vitamin D status: a critical analysis on the basis of evidence-based medicine. J Clin Endocrinol Metab (2013) 1.40
Withholding parenteral nutrition during critical illness increases plasma bilirubin but lowers the incidence of biliary sludge. Hepatology (2014) 1.40
Tight Glycemic Control in Critically Ill Children. N Engl J Med (2017) 1.39
Strict blood glucose control with insulin during intensive care after cardiac surgery: impact on 4-years survival, dependency on medical care, and quality-of-life. Eur Heart J (2006) 1.39
Worldwide Survey of Nutritional Practices in PICUs. Pediatr Crit Care Med (2016) 1.39
1,25-Dihydroxyvitamin D3 modulates expression of chemokines and cytokines in pancreatic islets: implications for prevention of diabetes in nonobese diabetic mice. Endocrinology (2005) 1.39
Transient Epstein-Barr virus reactivation in CD3 monoclonal antibody-treated patients. Blood (2009) 1.37
Immune regulation of 25-hydroxyvitamin-D3-1alpha-hydroxylase in human monocytes. J Bone Miner Res (2005) 1.37
Serum 3,3',5'-triiodothyronine (rT3) and 3,5,3'-triiodothyronine/rT3 are prognostic markers in critically ill patients and are associated with postmortem tissue deiodinase activities. J Clin Endocrinol Metab (2005) 1.37
Survival benefits of intensive insulin therapy in critical illness: impact of maintaining normoglycemia versus glycemia-independent actions of insulin. Diabetes (2006) 1.34
Role of disease and macronutrient dose in the randomized controlled EPaNIC trial: a post hoc analysis. Am J Respir Crit Care Med (2012) 1.34
Regulation of vitamin D homeostasis: implications for the immune system. Nutr Rev (2008) 1.33
Analogs of 1alpha,25-dihydroxyvitamin D3 as pluripotent immunomodulators. J Cell Biochem (2003) 1.31
Contribution of circulating lipids to the improved outcome of critical illness by glycemic control with intensive insulin therapy. J Clin Endocrinol Metab (2004) 1.31
Vitamin D and diabetes: its importance for beta cell and immune function. Mol Cell Endocrinol (2011) 1.30
The vitamin D receptor gene FokI polymorphism: functional impact on the immune system. Eur J Immunol (2007) 1.28
Insufficient activation of autophagy allows cellular damage to accumulate in critically ill patients. J Clin Endocrinol Metab (2011) 1.27
Differences in baseline lymphocyte counts and autoreactivity are associated with differences in outcome of islet cell transplantation in type 1 diabetic patients. Diabetes (2009) 1.27
The altered adrenal axis and treatment with glucocorticoids during critical illness. Nat Clin Pract Endocrinol Metab (2008) 1.20
Cytokines tumor necrosis factor-α and interferon-γ induce pancreatic β-cell apoptosis through STAT1-mediated Bim protein activation. J Biol Chem (2011) 1.20
Vitamin D insufficiency: implications for the immune system. Pediatr Nephrol (2010) 1.18
Intensive insulin therapy: enhanced Model Predictive Control algorithm versus standard care. Intensive Care Med (2008) 1.18
Human T lymphocytes are direct targets of 1,25-dihydroxyvitamin D3 in the immune system. J Steroid Biochem Mol Biol (2010) 1.18
Early parenteral nutrition evokes a phenotype of autophagy deficiency in liver and skeletal muscle of critically ill rabbits. Endocrinology (2012) 1.18
Glycemic penalty index for adequately assessing and comparing different blood glucose control algorithms. Crit Care (2008) 1.17
Interventions for preventing critical illness polyneuropathy and critical illness myopathy. Cochrane Database Syst Rev (2009) 1.16
The incidence of type 1 diabetes in the age group 0-39 years has not increased in Antwerp (Belgium) between 1989 and 2000: evidence for earlier disease manifestation. Diabetes Care (2002) 1.16
Effect of intensive insulin therapy on insulin sensitivity in the critically ill. J Clin Endocrinol Metab (2007) 1.16
Death protein 5 and p53-upregulated modulator of apoptosis mediate the endoplasmic reticulum stress-mitochondrial dialog triggering lipotoxic rodent and human β-cell apoptosis. Diabetes (2012) 1.16