Published in Endocrinology on July 31, 2003
The central melanocortin system directly controls peripheral lipid metabolism. J Clin Invest (2007) 2.97
The melanocortin-4 receptor: physiology, pharmacology, and pathophysiology. Endocr Rev (2010) 2.09
Leptin action in the dorsomedial hypothalamus increases sympathetic tone to brown adipose tissue in spite of systemic leptin resistance. J Neurosci (2011) 1.93
Chronic treatment with a melanocortin-4 receptor agonist causes weight loss, reduces insulin resistance, and improves cardiovascular function in diet-induced obese rhesus macaques. Diabetes (2012) 1.91
Central neural regulation of brown adipose tissue thermogenesis and energy expenditure. Cell Metab (2014) 1.85
Metabolic imprinting: critical impact of the perinatal environment on the regulation of energy homeostasis. Philos Trans R Soc Lond B Biol Sci (2006) 1.72
Sympathetic and sensory innervation of brown adipose tissue. Int J Obes (Lond) (2010) 1.71
Melanocortin-4 receptor mRNA expressed in sympathetic outflow neurons to brown adipose tissue: neuroanatomical and functional evidence. Am J Physiol Regul Integr Comp Physiol (2008) 1.41
Hypothalamic and hindbrain melanocortin receptors contribute to the feeding, thermogenic, and cardiovascular action of melanocortins. Endocrinology (2009) 1.41
Leptin and the systems neuroscience of meal size control. Front Neuroendocrinol (2009) 1.35
Energetic responses are triggered by caudal brainstem melanocortin receptor stimulation and mediated by local sympathetic effector circuits. Endocrinology (2008) 1.15
The role of the central melanocortin system in the regulation of food intake and energy homeostasis: lessons from mouse models. Philos Trans R Soc Lond B Biol Sci (2006) 1.14
Central melanocortin stimulation increases phosphorylated perilipin A and hormone-sensitive lipase in adipose tissues. Am J Physiol Regul Integr Comp Physiol (2010) 0.98
Sympathetic nervous system control of triglyceride metabolism: novel concepts derived from recent studies. J Lipid Res (2013) 0.96
Melanocortin control of energy balance: evidence from rodent models. Cell Mol Life Sci (2011) 0.94
Central nervous system regulation of brown adipose tissue. Compr Physiol (2014) 0.93
Characterization of a novel melanocortin receptor-containing node in the SNS outflow circuitry to brown adipose tissue involved in thermogenesis. Brain Res (2011) 0.93
Food intake reductions and increases in energetic responses by hindbrain leptin and melanotan II are enhanced in mice with POMC-specific PTP1B deficiency. Am J Physiol Endocrinol Metab (2012) 0.91
Melanocortin receptors, melanotropic peptides and penile erection. Curr Top Med Chem (2007) 0.91
Deficiency of PTP1B in POMC neurons leads to alterations in energy balance and homeostatic response to cold exposure. Am J Physiol Endocrinol Metab (2011) 0.90
Sense and nonsense in metabolic control of reproduction. Front Endocrinol (Lausanne) (2012) 0.87
Melanocortinergic control of penile erection. Peptides (2005) 0.82
Simultaneous POMC gene transfer to hypothalamus and brainstem increases physical activity, lipolysis and reduces adult-onset obesity. Eur J Neurosci (2011) 0.81
Metabolic transceivers: in tune with the central melanocortin system. Trends Endocrinol Metab (2012) 0.80
Melanocortin agonists stimulate lipolysis in human adipose tissue explants but not in adipocytes. BMC Res Notes (2015) 0.77
If I only had a whole brain: the importance of extrahypothalamic areas in the energy balance equation. Endocrinology (2009) 0.77
Testosterone replacement does not normalize carcass composition in chronically decerebrate male rats. Am J Physiol Regul Integr Comp Physiol (2009) 0.75
Intermittent MTII application evokes repeated anorexia and robust fat and weight loss. Peptides (2009) 0.75
The brainstem is a key target for neuroendocrine research on obesity. Endocrinology (2003) 0.75
Tim Bartness, Ph.D. (1953-2015). Temperature (Austin) (2016) 0.75
Nesfatin-1 in the Lateral Parabrachial Nucleus Inhibits Food Intake, Modulates Excitability of Glucosensing Neurons, and Enhances UCP1 Expression in Brown Adipose Tissue. Front Physiol (2017) 0.75
The taste reactivity test. I. Mimetic responses to gustatory stimuli in neurologically normal rats. Brain Res (1978) 3.31
Facilitation of synaptic transmission by EGL-30 Gqalpha and EGL-8 PLCbeta: DAG binding to UNC-13 is required to stimulate acetylcholine release. Neuron (1999) 3.04
Modulation of serotonin-controlled behaviors by Go in Caenorhabditis elegans. Science (1995) 3.03
Serotonin inhibition of synaptic transmission: Galpha(0) decreases the abundance of UNC-13 at release sites. Neuron (1999) 2.94
The biology of white adipocyte proliferation. Obes Rev (2001) 2.94
Synaptic code for sensory modalities revealed by C. elegans GLR-1 glutamate receptor. Nature (1995) 2.89
Mitosis-specific phosphorylation of p60c-src by p34cdc2-associated protein kinase. Cell (1989) 2.37
LIN-10 is a shared component of the polarized protein localization pathways in neurons and epithelia. Cell (1998) 1.93
CNS origins of the sympathetic nervous system outflow to brown adipose tissue. Am J Physiol (1999) 1.87
Central nervous system origins of the sympathetic nervous system outflow to white adipose tissue. Am J Physiol (1998) 1.85
The taste reactivity test. II. Mimetic responses to gustatory stimuli in chronic thalamic and chronic decerebrate rats. Brain Res (1978) 1.70
The EGL-3 proprotein convertase regulates mechanosensory responses of Caenorhabditis elegans. J Neurosci (2001) 1.70
Distinct signaling pathways mediate touch and osmosensory responses in a polymodal sensory neuron. J Neurosci (1999) 1.63
Cerebral infarction in patients with nephrotic syndrome. Stroke (1991) 1.57
Analytical issues in the evaluation of food deprivation and sucrose concentration effects on the microstructure of licking behavior in the rat. Behav Neurosci (1998) 1.56
Gustatory cortex in the rat. I. Physiological properties and cytoarchitecture. Brain Res (1986) 1.55
Brainstem application of melanocortin receptor ligands produces long-lasting effects on feeding and body weight. J Neurosci (1998) 1.54
Two distinct antigen-specific suppressor factors induced by the oral administration of antigen. J Exp Med (1980) 1.50
Infections in children caused by the HB group of bacteria. J Pediatr (1973) 1.49
Poland's syndrome. Report of seven cases and review of the literature. Clin Pediatr (Phila) (1972) 1.48
Chronically decerebrate rats demonstrate satiation but not bait shyness. Science (1978) 1.47
A mutation in v-src that removes a single conserved residue in the SH-2 domain of pp60v-src restricts transformation in a host-dependent manner. J Virol (1989) 1.40
The role of the dorsal vagal complex and the vagus nerve in feeding effects of melanocortin-3/4 receptor stimulation. Endocrinology (2000) 1.38
Signal transduction in the Caenorhabditis elegans nervous system. Annu Rev Neurosci (1998) 1.36
CaMKII regulates the density of central glutamatergic synapses in vivo. Nature (1999) 1.35
Catecholaminergic innervation of white adipose tissue in Siberian hamsters. Am J Physiol (1995) 1.34
G alphas-induced neurodegeneration in Caenorhabditis elegans. J Neurosci (1998) 1.24
Central gustatory lesions: II. Effects on sodium appetite, taste aversion learning, and feeding behaviors. Behav Neurosci (1991) 1.23
The regulation of total body fat: lessons learned from lipectomy studies. Neurosci Biobehav Rev (2001) 1.22
White adipose tissue sympathetic nervous system denervation increases fat pad mass and fat cell number. Am J Physiol (1998) 1.21
Pharmacologic studies in neonates given large dosages of ampicillin. J Pediatr (1974) 1.19
Influence of methodology upon apparent concentrations of antibiotics in tissue. Antimicrob Agents Chemother (1973) 1.19
Gustatory cortex in the rat. II. Thalamocortical projections. Brain Res (1986) 1.15
Taste reactivity as a dependent measure of the rapid formation of conditioned taste aversion: a tool for the neural analysis of taste-visceral associations. Behav Neurosci (1988) 1.15
Gonadal influences on adiposity. Int J Obes (1985) 1.15
Parabrachial gustatory lesions impair taste aversion learning in rats. Behav Neurosci (1992) 1.14
Sodium depletion enhances salt palatability in rats. Behav Neurosci (1984) 1.12
Photoperiodic control of seasonal body weight cycles in hamsters. Neurosci Biobehav Rev (1985) 1.11
Rat stereotaxic surgery without earbars. Physiol Behav (1983) 1.10
Production of p60c-src by baculovirus expression and immunoaffinity purification. Methods Enzymol (1991) 1.09
Hindbrain leptin and glucagon-like-peptide-1 receptor signaling interact to suppress food intake in an additive manner. Int J Obes (Lond) (2012) 1.08
CNS sympathetic outflow neurons to white fat that express MEL receptors may mediate seasonal adiposity. Am J Physiol Regul Integr Comp Physiol (2001) 1.08
Short-day increases in aggression are inversely related to circulating testosterone concentrations in male Siberian hamsters (Phodopus sungorus). Horm Behav (2000) 1.06
Control of the temporal locations of polydipsic licking in the rat. J Exp Anal Behav (1980) 1.04
Effects of foraging effort on body fat and food hoarding in Siberian hamsters. J Exp Zool (2001) 1.03
Effects of photoperiod and gonadectomy on food intake, body weight, and body composition in Siberian hamsters. Am J Physiol (1984) 1.02
Basis of pulmonary toxicity associated with cationic lipid-mediated gene transfer to the mammalian lung. Hum Gene Ther (1997) 1.02
Gender-related plasma levels of progesterone, interleukin-8 and interleukin-10 during and after cardiopulmonary bypass in infants and children. Crit Care (2001) 1.01
Lick rate analysis of sodium taste-state combinations. Am J Physiol (1993) 0.99
Adenovirus vector-infected cells can escape adenovirus antigen-specific cytotoxic T-lymphocyte killing in vivo. J Virol (1997) 0.99
Detection of mammaglobin expressing cells in blood of breast cancer patients. Cancer Lett (2000) 0.99
Relation of consummatory responses and preabsorptive insulin release to palatability and learned taste aversions. J Comp Physiol Psychol (1981) 0.99
Central melanocortin stimulation increases phosphorylated perilipin A and hormone-sensitive lipase in adipose tissues. Am J Physiol Regul Integr Comp Physiol (2010) 0.98
The forebrain is not essential for sympathoadrenal hyperglycemic response to glucoprivation. Science (1979) 0.97
A high fructose diet impairs spatial memory in male rats. Neurobiol Learn Mem (2009) 0.97
Sensory affect and motivation. Ann N Y Acad Sci (1977) 0.97
Antibody to CD40 ligand inhibits both humoral and cellular immune responses to adenoviral vectors and facilitates repeated administration to mouse airway. Gene Ther (1997) 0.97
Partial restoration of cAMP-stimulated CFTR chloride channel activity in DeltaF508 cells by deoxyspergualin. Am J Physiol (1998) 0.96
Quality of acquired responses to tastes by Rattus norvegicus depends on type of associated discomfort. J Comp Psychol (1983) 0.95
Neurochemical phenotype of sympathetic nervous system outflow from brain to white fat. Brain Res Bull (2001) 0.95
Fat pad-specific compensatory mass increases after varying degrees of lipectomy in Siberian hamsters. Am J Physiol (1997) 0.94
The effects of glossopharyngeal and chorda tympani nerve cuts on the ingestion and rejection of sapid stimuli: an electromyographic analysis in the rat. Behav Brain Res (1987) 0.94
Concentration-dependent licking of sucrose and sodium chloride in rats with parabrachial gustatory lesions. Physiol Behav (1993) 0.94
A quantitative comparison of taste reactivity behaviors to sucrose before and after lithium chloride pairings: a unidimensional account of palatability. Behav Neurosci (1992) 0.94
p53 autoantibodies in patients with primary ovarian cancer are associated with higher age, advanced stage and a higher proportion of p53-positive tumor cells. Oncology (1999) 0.94
Interoceptive and integrative contributions of forebrain and brainstem to energy balance control. Int J Obes Relat Metab Disord (2001) 0.94
Differential characteristics of two new tumorigenic cell lines of human breast carcinoma origin. Int J Cancer (1998) 0.93
Gustatory detection thresholds after parabrachial nuclei lesions in rats. Behav Neurosci (1995) 0.93
Effects of central oxytocin administration on intraoral intake of glucose in deprived and nondeprived rats. Physiol Behav (1997) 0.93
Body fat regulation after partial lipectomy in Siberian hamsters is photoperiod dependent and fat pad specific. Am J Physiol (1994) 0.93
Characterization of a novel melanocortin receptor-containing node in the SNS outflow circuitry to brown adipose tissue involved in thermogenesis. Brain Res (2011) 0.93
Bite size, ingestion rate, and meal size in lean and obese women. Appetite (1993) 0.93
Passive transfer of antibodies of maternal origin from blood to cerebrospinal fluid in infants. Lancet (1975) 0.92
Effects of postnatal estradiol and progesterone replacement in extremely preterm infants. J Clin Endocrinol Metab (1999) 0.92
Salt taste discrimination after bilateral section of the chorda tympani or glossopharyngeal nerves. Am J Physiol (1992) 0.91
Serotonin receptors in the caudal brainstem are necessary and sufficient for the anorectic effect of peripherally administered mCPP. Psychopharmacology (Berl) (1998) 0.91
Food deprivation-induced increases in hoarding by Siberian hamsters are not photoperiod-dependent. Physiol Behav (1996) 0.91
Glucagon stimulation of brown adipose tissue growth and thermogenesis. Am J Physiol (1987) 0.90
Effect of hepatic glucose infusion on glucose intake and licking microstructure in deprived and nondeprived rats. Am J Physiol (1999) 0.90
Prognostic value of genomic alterations in minimal residual cancer cells purified from the blood of breast cancer patients. Br J Cancer (2000) 0.90
Adenovirus-mediated persistent cystic fibrosis transmembrane conductance regulator expression in mouse airway epithelium. J Virol (1998) 0.90
Generation of cytotoxic T lymphocytes against immunorecessive epitopes after multiple immunizations with adenovirus vectors is dependent on haplotype. J Virol (1997) 0.90
Opioids and consummatory behavior. Brain Res Bull (1985) 0.90
Lesions of the central nucleus of the amygdala. I: Effects on taste reactivity, taste aversion learning and sodium appetite. Behav Brain Res (1993) 0.90
Neurological tests and behavioral deficits in chronic thalamic and chronic decerebrate rats. Brain Res (1978) 0.90
Clinical pharmacology of tobramycin in newborns. Am J Dis Child (1973) 0.89
Photoperiod-peptide interactions in the energy intake of Siberian hamsters. Peptides (1987) 0.89
Sodium homeostasis in chronic decerebrate rats. Behav Neurosci (1986) 0.88
Dynamics of gastric emptying during and after stomach fill. Am J Physiol (1992) 0.88
Suprachiasmatic and paraventricular control of photoperiodism in Siberian hamsters. Am J Physiol (1991) 0.88
Chemospecific deficits in taste detection after selective gustatory deafferentation in rats. Am J Physiol (1990) 0.88
Synthesis of biotin-labelled dexamethasone derivatives. Novel hormone-affinity probes. Eur J Biochem (1983) 0.88
Neurological dissociation of gastrointestinal and metabolic contributions to meal size control. Behav Neurosci (1994) 0.88
Pulmonary dysfunction and reduced exercise capacity in patients with myelomeningocele. J Pediatr (1997) 0.88
Intraoral intake and taste reactivity responses elicited by sucrose and sodium chloride in chronic decerebrate rats. Behav Neurosci (1988) 0.88
Role of short photoperiod and cold exposure in regulating daily torpor in Djungarian hamsters. J Comp Physiol A (1987) 0.87