John P Manis

Author PubWeight™ 51.06‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice. Proc Natl Acad Sci U S A 2003 9.14
2 MDC1 maintains genomic stability by participating in the amplification of ATM-dependent DNA damage signals. Mol Cell 2006 6.09
3 IgH class switching and translocations use a robust non-classical end-joining pathway. Nature 2007 6.05
4 H2AX prevents DNA breaks from progressing to chromosome breaks and translocations. Mol Cell 2006 3.53
5 The AID antibody diversification enzyme is regulated by protein kinase A phosphorylation. Nature 2005 2.63
6 Deficiencies of GM-CSF and interferon gamma link inflammation and cancer. J Exp Med 2003 2.36
7 p63 and p73 are not required for the development and p53-dependent apoptosis of T cells. Cancer Cell 2004 1.86
8 Artemis and p53 cooperate to suppress oncogenic N-myc amplification in progenitor B cells. Proc Natl Acad Sci U S A 2004 1.53
9 Leucine-rich repeat containing 8A (LRRC8A) is essential for T lymphocyte development and function. J Exp Med 2014 1.49
10 Oncogenic transformation in the absence of Xrcc4 targets peripheral B cells that have undergone editing and switching. J Exp Med 2008 1.47
11 Internal IgH class switch region deletions are position-independent and enhanced by AID expression. Proc Natl Acad Sci U S A 2002 1.44
12 53BP1 and p53 synergize to suppress genomic instability and lymphomagenesis. Proc Natl Acad Sci U S A 2006 1.27
13 Pathways that suppress programmed DNA breaks from progressing to chromosomal breaks and translocations. DNA Repair (Amst) 2006 1.24
14 Immature B cells preferentially switch to IgE with increased direct Sμ to Sε recombination. J Exp Med 2011 1.24
15 BBAP monoubiquitylates histone H4 at lysine 91 and selectively modulates the DNA damage response. Mol Cell 2009 1.23
16 AID-induced genotoxic stress promotes B cell differentiation in the germinal center via ATM and LKB1 signaling. Mol Cell 2010 1.16
17 SOCS3 protein developmentally regulates the chemokine receptor CXCR4-FAK signaling pathway during B lymphopoiesis. Immunity 2007 1.10
18 Artemis-independent functions of DNA-dependent protein kinase in Ig heavy chain class switch recombination and development. Proc Natl Acad Sci U S A 2005 1.02
19 Signatures of murine B-cell development implicate Yy1 as a regulator of the germinal center-specific program. Proc Natl Acad Sci U S A 2011 1.02
20 Downstream class switching leads to IgE antibody production by B lymphocytes lacking IgM switch regions. Proc Natl Acad Sci U S A 2010 0.96
21 The function of AID in somatic mutation and class switch recombination: upstream or downstream of DNA breaks. J Exp Med 2002 0.96
22 Fixing DNA breaks during class switch recombination. J Exp Med 2008 0.90
23 Deficiency of base excision repair enzyme NEIL3 drives increased predisposition to autoimmunity. J Clin Invest 2016 0.85
24 Analysis of mice lacking DNaseI hypersensitive sites at the 5' end of the IgH locus. PLoS One 2010 0.83
25 Correction: Complex Breakpoints and Template Switching Associated with Non-canonical Termination of Homologous Recombination in Mammalian Cells. PLoS Genet 2016 0.75