PubRank

Ken Hirotsu

Author PubWeight™ 30.53‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Structural determinants for branched-chain aminotransferase isozyme-specific inhibition by the anticonvulsant drug gabapentin. J Biol Chem 2005 1.05
2 Three-dimensional structure of the flavoenzyme acyl-CoA oxidase-II from rat liver, the peroxisomal counterpart of mitochondrial acyl-CoA dehydrogenase. J Biochem 2002 1.05
3 Crystal structure of monofunctional histidinol phosphate phosphatase from Thermus thermophilus HB8. Biochemistry 2007 1.03
4 Crystal structures of CTP synthetase reveal ATP, UTP, and glutamine binding sites. Structure 2004 1.01
5 Structure of the transition state analog of medium-chain acyl-CoA dehydrogenase. Crystallographic and molecular orbital studies on the charge-transfer complex of medium-chain acyl-CoA dehydrogenase with 3-thiaoctanoyl-CoA. J Biochem 2003 0.97
6 Crystal structure of quinohemoprotein amine dehydrogenase from Pseudomonas putida. Identification of a novel quinone cofactor encaged by multiple thioether cross-bridges. J Biol Chem 2001 0.96
7 Structure of imidazole glycerol phosphate synthase from Thermus thermophilus HB8: open-closed conformational change and ammonia tunneling. J Biochem 2002 0.94
8 Structure of D-alanine-D-alanine ligase from Thermus thermophilus HB8: cumulative conformational change and enzyme-ligand interactions. Acta Crystallogr D Biol Crystallogr 2009 0.94
9 Crystal structures of branched-chain amino acid aminotransferase complexed with glutamate and glutarate: true reaction intermediate and double substrate recognition of the enzyme. Biochemistry 2003 0.91
10 Crystal structures of nonoxidative zinc-dependent 2,6-dihydroxybenzoate (gamma-resorcylate) decarboxylase from Rhizobium sp. strain MTP-10005. J Biol Chem 2006 0.91
11 Reaction mechanism and molecular basis for selenium/sulfur discrimination of selenocysteine lyase. J Biol Chem 2010 0.90
12 Strain and catalysis in aspartate aminotransferase. Biochim Biophys Acta 2003 0.88
13 Crystal structures of glutamine:phenylpyruvate aminotransferase from Thermus thermophilus HB8: induced fit and substrate recognition. J Biol Chem 2004 0.88
14 Crystal structure of a homolog of mammalian serine racemase from Schizosaccharomyces pombe. J Biol Chem 2009 0.86
15 Three-dimensional structure of rat-liver acyl-CoA oxidase in complex with a fatty acid: insights into substrate-recognition and reactivity toward molecular oxygen. J Biochem 2006 0.85
16 Crystallization screening test for the whole-cell project on Thermus thermophilus HB8. Acta Crystallogr Sect F Struct Biol Cryst Commun 2008 0.84
17 Extremely Long C-C Bond in (-)-trans-1,2-Di-tert-butyl-1,2-diphenyl- and 1,1-Di-tert-butyl-2,2-diphenyl-3,8-dichlorocyclobuta[b]naphthalenes. J Org Chem 1999 0.84
18 X-Ray crystallographic and mutational studies of fluoroacetate dehalogenase from Burkholderia sp. strain FA1. J Bacteriol 2009 0.83
19 Crystal structure of the tandem-type universal stress protein TTHA0350 from Thermus thermophilus HB8. J Biochem 2011 0.82
20 Glutamine:phenylpyruvate aminotransferase from an extremely thermophilic bacterium, Thermus thermophilus HB8. J Biochem 2003 0.81
21 Remarkable structure deformation in phenothiazine trimer radical cation. Org Lett 2004 0.81
22 Expression, purification and preliminary X-ray characterization of N-acetyl-gamma-glutamyl-phosphate reductase from Thermus thermophilus HB8. Acta Crystallogr D Biol Crystallogr 2003 0.80
23 A new family of NAD(P)H-dependent oxidoreductases distinct from conventional Rossmann-fold proteins. J Biosci Bioeng 2005 0.80
24 Characterization of histidinol phosphate aminotransferase from Escherichia coli. Biochim Biophys Acta 2003 0.80
25 Structures of argininosuccinate synthetase in enzyme-ATP substrates and enzyme-AMP product forms: stereochemistry of the catalytic reaction. J Biol Chem 2003 0.80
26 Expression, purification and preliminary X-ray characterization of DL-2-haloacid dehalogenase from Methylobacterium sp. CPA1. Acta Crystallogr Sect F Struct Biol Cryst Commun 2007 0.80
27 Crystal structures of threonine synthase from Thermus thermophilus HB8: conformational change, substrate recognition, and mechanism. J Biol Chem 2003 0.80
28 Serine racemase with catalytically active lysinoalanyl residue. J Biochem 2009 0.79
29 Conformational change in aspartate aminotransferase on substrate binding induces strain in the catalytic group and enhances catalysis. J Biol Chem 2002 0.79
30 Engineering the substrate specificity of porcine kidney D-amino acid oxidase by mutagenesis of the "active-site lid". J Biochem 2006 0.78
31 Crystal structure of argininosuccinate synthetase from Thermus thermophilus HB8. Structural basis for the catalytic action. J Biol Chem 2002 0.78
32 Crystal structures of Delta1-piperideine-2-carboxylate/Delta1-pyrroline-2-carboxylate reductase belonging to a new family of NAD(P)H-dependent oxidoreductases: conformational change, substrate recognition, and stereochemistry of the reaction. J Biol Chem 2005 0.77
33 Binding of C5-dicarboxylic substrate to aspartate aminotransferase: implications for the conformational change at the transaldimination step. Biochemistry 2005 0.77
34 Substrate specificity of fluoroacetate dehalogenase: an insight from crystallographic analysis, fluorescence spectroscopy, and theoretical computations. Chemistry 2012 0.77
35 Effects of hydrogen bonds in association with flavin and substrate in flavoenzyme d-amino acid oxidase. The catalytic and structural roles of Gly313 and Thr317. J Biochem 2002 0.77
36 Expression, purification and preliminary X-ray characterization of CTP synthetase from Thermus thermophilus HB8. Acta Crystallogr D Biol Crystallogr 2003 0.76
37 Structures of hypoxanthine-guanine phosphoribosyltransferase (TTHA0220) from Thermus thermophilus HB8. Acta Crystallogr Sect F Struct Biol Cryst Commun 2010 0.75
38 Binding modes of DL-2-haloacid dehalogenase revealed by crystallography, modeling and isotope effects studies. Arch Biochem Biophys 2013 0.75
39 Expression, purification and preliminary X-ray characterization of histidinol phosphate phosphatase. Acta Crystallogr D Biol Crystallogr 2004 0.75
40 Mechanism of preferential enrichment, an unusual enantiomeric resolution phenomenon caused by polymorphic transition during crystallization of mixed crystals composed of two enantiomers. J Am Chem Soc 2002 0.75
41 The active site structure of quinohemoprotein amine dehydrogenase inhibited by p-nitrophenylhydrazine. Biochim Biophys Acta 2003 0.75