Published in Structure on August 01, 2004
Large-scale filament formation inhibits the activity of CTP synthetase. Elife (2014) 1.06
CTP synthetase and its role in phospholipid synthesis in the yeast Saccharomyces cerevisiae. Prog Lipid Res (2008) 0.99
Mechanisms of product feedback regulation and drug resistance in cytidine triphosphate synthetases from the structure of a CTP-inhibited complex. Biochemistry (2005) 0.98
Phosphorylation of human CTP synthetase 1 by protein kinase C: identification of Ser(462) and Thr(455) as major sites of phosphorylation. J Biol Chem (2007) 0.91
Structure of the synthetase domain of human CTP synthetase, a target for anticancer therapy. Acta Crystallogr Sect F Struct Biol Cryst Commun (2006) 0.91
Expression of Human CTP synthetase in Saccharomyces cerevisiae reveals phosphorylation by protein kinase A. J Biol Chem (2005) 0.91
Nucleotide synthesis is regulated by cytoophidium formation during neurodevelopment and adaptive metabolism. Biol Open (2014) 0.91
Regulation of human cytidine triphosphate synthetase 2 by phosphorylation. J Biol Chem (2010) 0.90
Gates of enzymes. Chem Rev (2013) 0.90
Phosphorylation of CTP synthetase from Saccharomyces cerevisiae by protein kinase C. J Biol Chem (1995) 0.87
Formylglycinamide ribonucleotide amidotransferase from Thermotoga maritima: structural insights into complex formation. Biochemistry (2008) 0.84
Specific reactions of S-nitrosothiols with cysteine hydrolases: A comparative study between dimethylargininase-1 and CTP synthetase. Protein Sci (2007) 0.83
Phosphorylation of human CTP synthetase 1 by protein kinase A: identification of Thr455 as a major site of phosphorylation. J Biol Chem (2006) 0.83
Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG. Chem Biol (2015) 0.81
Structure of the dimeric form of CTP synthase from Sulfolobus solfataricus. Acta Crystallogr Sect F Struct Biol Cryst Commun (2011) 0.79
Active site coupling in Plasmodium falciparum GMP synthetase is triggered by domain rotation. Nat Commun (2015) 0.76
Ubiquitination and filamentous structure of cytidine triphosphate synthase. Fly (Austin) (2016) 0.75
Inference of S-system models of genetic networks using a cooperative coevolutionary algorithm. Bioinformatics (2004) 1.96
Structural basis of the substrate-specific two-step catalysis of long chain fatty acyl-CoA synthetase dimer. J Biol Chem (2004) 1.89
Structure of dNTP-inducible dNTP triphosphohydrolase: insight into broad specificity for dNTPs and triphosphohydrolase-type hydrolysis. Acta Crystallogr D Biol Crystallogr (2007) 1.29
Transcription activation mediated by a cyclic AMP receptor protein from Thermus thermophilus HB8. J Bacteriol (2007) 1.17
Identification of severe combined immunodeficiency by T-cell receptor excision circles quantification using neonatal guthrie cards. J Pediatr (2009) 1.15
Quantification of κ-deleting recombination excision circles in Guthrie cards for the identification of early B-cell maturation defects. J Allergy Clin Immunol (2011) 1.13
Structure of RecJ exonuclease defines its specificity for single-stranded DNA. J Biol Chem (2010) 1.11
Dual substrate recognition of aminotransferases. Chem Rec (2005) 1.10
Molecular and clinical analysis of RAF1 in Noonan syndrome and related disorders: dephosphorylation of serine 259 as the essential mechanism for mutant activation. Hum Mutat (2010) 1.08
Common variable immunodeficiency classification by quantifying T-cell receptor and immunoglobulin κ-deleting recombination excision circles. J Allergy Clin Immunol (2012) 1.07
Three-dimensional structure of the flavoenzyme acyl-CoA oxidase-II from rat liver, the peroxisomal counterpart of mitochondrial acyl-CoA dehydrogenase. J Biochem (2002) 1.05
Structural determinants for branched-chain aminotransferase isozyme-specific inhibition by the anticonvulsant drug gabapentin. J Biol Chem (2005) 1.05
Crystal structure of monofunctional histidinol phosphate phosphatase from Thermus thermophilus HB8. Biochemistry (2007) 1.03
Structural insights into the Thermus thermophilus ADP-ribose pyrophosphatase mechanism via crystal structures with the bound substrate and metal. J Biol Chem (2004) 1.01
Novel reaction mechanism of GTP cyclohydrolase I. High-resolution X-ray crystallography of Thermus thermophilus HB8 enzyme complexed with a transition state analogue, the 8-oxoguanine derivative. J Biochem (2005) 0.99
Bound nucleotide controls the endonuclease activity of mismatch repair enzyme MutL. J Biol Chem (2008) 0.99
Molecular mechanisms of the whole DNA repair system: a comparison of bacterial and eukaryotic systems. J Nucleic Acids (2010) 0.96
Crystal structure of quinohemoprotein amine dehydrogenase from Pseudomonas putida. Identification of a novel quinone cofactor encaged by multiple thioether cross-bridges. J Biol Chem (2001) 0.96
Characterization of DNA polymerase X from Thermus thermophilus HB8 reveals the POLXc and PHP domains are both required for 3'-5' exonuclease activity. Nucleic Acids Res (2009) 0.96
Structure of P-protein of the glycine cleavage system: implications for nonketotic hyperglycinemia. EMBO J (2005) 0.95
Role of RecJ-like protein with 5'-3' exonuclease activity in oligo(deoxy)nucleotide degradation. J Biol Chem (2010) 0.95
An O6-methylguanine-DNA methyltransferase-like protein from Thermus thermophilus interacts with a nucleotide excision repair protein. J Biochem (2008) 0.94
Structure of D-alanine-D-alanine ligase from Thermus thermophilus HB8: cumulative conformational change and enzyme-ligand interactions. Acta Crystallogr D Biol Crystallogr (2009) 0.94
Structure of imidazole glycerol phosphate synthase from Thermus thermophilus HB8: open-closed conformational change and ammonia tunneling. J Biochem (2002) 0.94
Crystal structure of family 5 uracil-DNA glycosylase bound to DNA. J Mol Biol (2007) 0.93
Structural basis for different substrate specificities of two ADP-ribose pyrophosphatases from Thermus thermophilus HB8. J Bacteriol (2007) 0.92
Crystal structures of branched-chain amino acid aminotransferase complexed with glutamate and glutarate: true reaction intermediate and double substrate recognition of the enzyme. Biochemistry (2003) 0.91
Crystal structures of nonoxidative zinc-dependent 2,6-dihydroxybenzoate (gamma-resorcylate) decarboxylase from Rhizobium sp. strain MTP-10005. J Biol Chem (2006) 0.91
Reaction mechanism and molecular basis for selenium/sulfur discrimination of selenocysteine lyase. J Biol Chem (2010) 0.90
Molecular mechanism of the Thermus thermophilus ADP-ribose pyrophosphatase from mutational and kinetic studies. Biochemistry (2005) 0.90
Structural insights into the enzymatic mechanism of serine palmitoyltransferase from Sphingobacterium multivorum. J Biochem (2009) 0.90
Multiple reversions of an IL2RG mutation restore T cell function in an X-linked severe combined immunodeficiency patient. J Clin Immunol (2012) 0.89
Insights into different dependence of dNTP triphosphohydrolase on metal ion species from intracellular ion concentrations in Thermus thermophilus. Extremophiles (2007) 0.89
Ligand-induced conformational changes and a reaction intermediate in branched-chain 2-oxo acid dehydrogenase (E1) from Thermus thermophilus HB8, as revealed by X-ray crystallography. J Mol Biol (2004) 0.89
Strain and catalysis in aspartate aminotransferase. Biochim Biophys Acta (2003) 0.88
Crystal structures of glutamine:phenylpyruvate aminotransferase from Thermus thermophilus HB8: induced fit and substrate recognition. J Biol Chem (2004) 0.88
Crystal structure of MutS2 endonuclease domain and the mechanism of homologous recombination suppression. J Biol Chem (2008) 0.88
A single amino acid limits the substrate specificity of Thermus thermophilus uridine-cytidine kinase to cytidine. Biochemistry (2011) 0.87
Two dNTP triphosphohydrolases from Pseudomonas aeruginosa possess diverse substrate specificities. FEBS J (2009) 0.86
Crystal structure of the conserved hypothetical protein TTHA1606 from Thermus thermophilus HB8. Proteins (2009) 0.86
ATP-induced structural change of dephosphocoenzyme A kinase from Thermus thermophilus HB8. Proteins (2005) 0.86
Crystal structure of a homolog of mammalian serine racemase from Schizosaccharomyces pombe. J Biol Chem (2009) 0.86
Three-dimensional structure of rat-liver acyl-CoA oxidase in complex with a fatty acid: insights into substrate-recognition and reactivity toward molecular oxygen. J Biochem (2006) 0.85
Crystal structure of TTHA0252 from Thermus thermophilus HB8, a RNA degradation protein of the metallo-beta-lactamase superfamily. J Biochem (2006) 0.85
Crystallization screening test for the whole-cell project on Thermus thermophilus HB8. Acta Crystallogr Sect F Struct Biol Cryst Commun (2008) 0.84
Improved heterologous gene expression in Escherichia coli by optimization of the AT-content of codons immediately downstream of the initiation codon. J Biotechnol (2005) 0.84
Extremely Long C-C Bond in (-)-trans-1,2-Di-tert-butyl-1,2-diphenyl- and 1,1-Di-tert-butyl-2,2-diphenyl-3,8-dichlorocyclobuta[b]naphthalenes. J Org Chem (1999) 0.84
Cloning, expression, purification, crystallization and preliminary X-ray crystallographic study of the putative SAICAR synthetase (PH0239) from Pyrococcus horikoshii OT3. Acta Crystallogr Sect F Struct Biol Cryst Commun (2010) 0.83
X-Ray crystallographic and mutational studies of fluoroacetate dehalogenase from Burkholderia sp. strain FA1. J Bacteriol (2009) 0.83
Very rapid induction of a cold shock protein by temperature downshift in Thermus thermophilus. Biochem Biophys Res Commun (2010) 0.83
Clinical profile and genetic basis of Wiskott-Aldrich syndrome at Chandigarh, North India. Asian Pac J Allergy Immunol (2012) 0.82
The role of ribonucleases in regulating global mRNA levels in the model organism Thermus thermophilus HB8. BMC Genomics (2014) 0.82
Overproduction, crystallization and preliminary diffraction data of ADP-ribose pyrophosphatase from Thermus thermophilus HB8. Acta Crystallogr D Biol Crystallogr (2003) 0.82
Crystal structure of the tandem-type universal stress protein TTHA0350 from Thermus thermophilus HB8. J Biochem (2011) 0.82
Structures of apo and GTP-bound molybdenum cofactor biosynthesis protein MoaC from Thermus thermophilus HB8. Acta Crystallogr D Biol Crystallogr (2010) 0.82
Glutamine:phenylpyruvate aminotransferase from an extremely thermophilic bacterium, Thermus thermophilus HB8. J Biochem (2003) 0.81
The structural basis of the kinetic mechanism of a gap-filling X-family DNA polymerase that binds Mg(2+)-dNTP before binding to DNA. J Mol Biol (2012) 0.81
Analysis of a nuclease activity of catalytic domain of Thermus thermophilus MutS2 by high-accuracy mass spectrometry. Nucleic Acids Res (2007) 0.81
Crystal structure of an archaeal cleavage and polyadenylation specificity factor subunit from Pyrococcus horikoshii. Proteins (2010) 0.81
Crystal structure of the ligand-binding form of nanoRNase from Bacteroides fragilis, a member of the DHH/DHHA1 phosphoesterase family of proteins. FEBS Lett (2013) 0.81
Remarkable structure deformation in phenothiazine trimer radical cation. Org Lett (2004) 0.81
A novel single-stranded DNA-specific 3'-5' exonuclease, Thermus thermophilus exonuclease I, is involved in several DNA repair pathways. Nucleic Acids Res (2010) 0.81
Structure of TTHA1623, a novel metallo-beta-lactamase superfamily protein from Thermus thermophilus HB8. Acta Crystallogr Sect F Struct Biol Cryst Commun (2009) 0.80
Expression, purification and preliminary X-ray characterization of DL-2-haloacid dehalogenase from Methylobacterium sp. CPA1. Acta Crystallogr Sect F Struct Biol Cryst Commun (2007) 0.80
Structures of argininosuccinate synthetase in enzyme-ATP substrates and enzyme-AMP product forms: stereochemistry of the catalytic reaction. J Biol Chem (2003) 0.80
Crystal structures of threonine synthase from Thermus thermophilus HB8: conformational change, substrate recognition, and mechanism. J Biol Chem (2003) 0.80
Crystallization and preliminary X-ray diffraction analysis of ribosomal protein L11 methyltransferase from Thermus thermophilus HB8. Acta Crystallogr D Biol Crystallogr (2003) 0.80
Expression, purification and preliminary X-ray characterization of N-acetyl-gamma-glutamyl-phosphate reductase from Thermus thermophilus HB8. Acta Crystallogr D Biol Crystallogr (2003) 0.80
A new family of NAD(P)H-dependent oxidoreductases distinct from conventional Rossmann-fold proteins. J Biosci Bioeng (2005) 0.80
Characterization of histidinol phosphate aminotransferase from Escherichia coli. Biochim Biophys Acta (2003) 0.80
Serine racemase with catalytically active lysinoalanyl residue. J Biochem (2009) 0.79
Conformational change in aspartate aminotransferase on substrate binding induces strain in the catalytic group and enhances catalysis. J Biol Chem (2002) 0.79