PubRank

Thomas G Graeber

Author PubWeight™ 79.07‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E). Nature 2011 10.77
2 Myc-driven murine prostate cancer shares molecular features with human prostate tumors. Cancer Cell 2003 6.38
3 An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells. Science 2013 5.10
4 Cell autonomous role of PTEN in regulating castration-resistant prostate cancer growth. Cancer Cell 2011 4.43
5 BCL6 enables Ph+ acute lymphoblastic leukaemia cells to survive BCR-ABL1 kinase inhibition. Nature 2011 3.63
6 TLR activation triggers the rapid differentiation of monocytes into macrophages and dendritic cells. Nat Med 2005 2.62
7 An integrated approach to dissecting oncogene addiction implicates a Myb-coordinated self-renewal program as essential for leukemia maintenance. Genes Dev 2011 2.38
8 Type I interferon suppresses type II interferon-triggered human anti-mycobacterial responses. Science 2013 2.34
9 Host immunity contributes to the anti-melanoma activity of BRAF inhibitors. J Clin Invest 2013 2.30
10 BRAF inhibitor vemurafenib improves the antitumor activity of adoptive cell immunotherapy. Cancer Res 2012 2.14
11 Phosphorylation of the ATP-binding loop directs oncogenicity of drug-resistant BCR-ABL mutants. Proc Natl Acad Sci U S A 2006 2.13
12 BACH2 mediates negative selection and p53-dependent tumor suppression at the pre-B cell receptor checkpoint. Nat Med 2013 1.79
13 Use of genetic profiling in leprosy to discriminate clinical forms of the disease. Science 2003 1.73
14 CTLA4 blockade broadens the peripheral T-cell receptor repertoire. Clin Cancer Res 2014 1.66
15 Sterol regulatory element-binding proteins are essential for the metabolic programming of effector T cells and adaptive immunity. Nat Immunol 2013 1.61
16 Antitumor activity of the ERK inhibitor SCH772984 [corrected] against BRAF mutant, NRAS mutant and wild-type melanoma. Mol Cancer 2014 1.59
17 Rank-rank hypergeometric overlap: identification of statistically significant overlap between gene-expression signatures. Nucleic Acids Res 2010 1.45
18 MicroRNA-21 targets the vitamin D-dependent antimicrobial pathway in leprosy. Nat Med 2012 1.43
19 18F-fluorodeoxy-glucose positron emission tomography marks MYC-overexpressing human basal-like breast cancers. Cancer Res 2011 1.36
20 Integrative analysis of the microbiome and metabolome of the human intestinal mucosal surface reveals exquisite inter-relationships. Microbiome 2013 1.32
21 Oncogene-specific activation of tyrosine kinase networks during prostate cancer progression. Proc Natl Acad Sci U S A 2012 1.32
22 Visualization and interpretation of protein networks in Mycobacterium tuberculosis based on hierarchical clustering of genome-wide functional linkage maps. Nucleic Acids Res 2003 1.31
23 A microfluidic platform for systems pathology: multiparameter single-cell signaling measurements of clinical brain tumor specimens. Cancer Res 2010 1.20
24 Glucose deprivation activates a metabolic and signaling amplification loop leading to cell death. Mol Syst Biol 2012 1.20
25 Vascular endothelial growth factor receptor 2 plays a role in the activation of aortic endothelial cells by oxidized phospholipids. Arterioscler Thromb Vasc Biol 2006 1.17
26 NOD2 triggers an interleukin-32-dependent human dendritic cell program in leprosy. Nat Med 2012 1.14
27 Metastatic castration-resistant prostate cancer reveals intrapatient similarity and interpatient heterogeneity of therapeutic kinase targets. Proc Natl Acad Sci U S A 2013 1.12
28 A metaproteomic approach to study human-microbial ecosystems at the mucosal luminal interface. PLoS One 2011 1.12
29 An essential requirement for the SCAP/SREBP signaling axis to protect cancer cells from lipotoxicity. Cancer Res 2013 1.12
30 Gene expression in epithelial ovarian carcinoma. Oncogene 2002 1.05
31 Doxycycline alters metabolism and proliferation of human cell lines. PLoS One 2013 1.01
32 Integrated microfluidic and imaging platform for a kinase activity radioassay to analyze minute patient cancer samples. Cancer Res 2010 0.98
33 Activation of aortic endothelial cells by oxidized phospholipids: a phosphoproteomic analysis. J Proteome Res 2010 0.97
34 The impact of ex vivo clinical grade activation protocols on human T-cell phenotype and function for the generation of genetically modified cells for adoptive cell transfer therapy. J Immunother 2010 0.88
35 Cross-species comparisons of cancer signaling. Nat Genet 2005 0.84
36 Heterogeneity of molecular targets on clonal cancer lines derived from a novel hormone-refractory prostate cancer tumor system. Prostate 2003 0.82
37 Determining PTEN functional status by network component deduced transcription factor activities. PLoS One 2012 0.79
38 Phosphoproteomic analysis of aortic endothelial cells activated by oxidized phospholipids. Methods Mol Biol 2013 0.76
39 Host immunity contributes to the anti-melanoma activity of BRAF inhibitors. J Clin Invest 2015 0.76
40 Corrigendum: Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia. Nature 2016 0.75