Published in J Leukoc Biol on September 12, 2003
Chemokines: integrators of pain and inflammation. Nat Rev Drug Discov (2005) 1.68
Viewing chemokines as a third major system of communication in the brain. AAPS J (2006) 1.39
Adenosine A2a receptors induce heterologous desensitization of chemokine receptors. Blood (2006) 1.19
Modulation of chemokine receptor activity through dimerization and crosstalk. Cell Mol Life Sci (2009) 1.15
Modulation of neuronal CXCR4 by the micro-opioid agonist DAMGO. J Neurovirol (2006) 1.11
Morphine increases brain levels of ferritin heavy chain leading to inhibition of CXCR4-mediated survival signaling in neurons. J Neurosci (2009) 1.10
CCR2 mediates increases in glial activation caused by exposure to HIV-1 Tat and opiates. J Neuroimmunol (2006) 1.04
CCL5/RANTES gene deletion attenuates opioid-induced increases in glial CCL2/MCP-1 immunoreactivity and activation in HIV-1 Tat-exposed mice. J Neuroimmune Pharmacol (2008) 1.02
Rapid heterologous desensitization of antinociceptive activity between mu or delta opioid receptors and chemokine receptors in rats. Drug Alcohol Depend (2006) 0.99
Bi-directional heterologous desensitization between the major HIV-1 co-receptor CXCR4 and the kappa-opioid receptor. J Neuroimmunol (2008) 0.99
Opioids and HIV/HCV infection. J Neuroimmune Pharmacol (2011) 0.91
Mechanisms regulating chemokine receptor activity. Immunology (2011) 0.89
Morphine, but not trauma, sensitizes to systemic Acinetobacter baumannii infection. J Neuroimmune Pharmacol (2011) 0.88
GTPgammaS incorporation in the rat brain: a study on mu-opioid receptors and CXCR4. J Neuroimmune Pharmacol (2007) 0.88
A novel bivalent HIV-1 entry inhibitor reveals fundamental differences in CCR5-μ-opioid receptor interactions between human astroglia and microglia. AIDS (2013) 0.88
Interactions between chemokine and mu-opioid receptors: anatomical findings and electrophysiological studies in the rat periaqueductal grey. Brain Behav Immun (2010) 0.86
HIV-1 alters neural and glial progenitor cell dynamics in the central nervous system: coordinated response to opiates during maturation. Glia (2012) 0.84
Depletion and recovery of lymphoid subsets following morphine administration. Br J Pharmacol (2011) 0.84
Fractalkine/CX3CL1 protects striatal neurons from synergistic morphine and HIV-1 Tat-induced dendritic losses and death. Mol Neurodegener (2011) 0.83
Far from the heart: Receptor cross-talk in remote conditioning. Nat Med (2010) 0.82
Protein kinase Czeta mediates micro-opioid receptor-induced cross-desensitization of chemokine receptor CCR5. J Biol Chem (2011) 0.82
Regulation of neuronal ferritin heavy chain, a new player in opiate-induced chemokine dysfunction. J Neuroimmune Pharmacol (2011) 0.81
A Bivalent Ligand Targeting the Putative Mu Opioid Receptor and Chemokine Receptor CCR5 Heterodimers: Binding Affinity versus Functional Activities. Medchemcomm (2013) 0.81
An in vitro model of morphine withdrawal manifests the enhancing effect on human immunodeficiency virus infection of human T lymphocytes through the induction of substance P. Am J Pathol (2006) 0.80
Opioids and the immune system: what is their mechanism of action? Br J Pharmacol (2011) 0.78
Functions of the chemokine receptor CXCR4 in the central nervous system and its regulation by μ-opioid receptors. Int Rev Neurobiol (2014) 0.78
Cross-desensitization of CCR1, but not CCR2, following activation of the formyl peptide receptor FPR1. J Immunol (2014) 0.77
Breaking barriers to novel analgesic drug development. Nat Rev Drug Discov (2017) 0.77
PKA and ERK1/2 are involved in dopamine D₁ receptor-induced heterologous desensitization of the δ opioid receptor. Life Sci (2013) 0.76
Opiate addiction therapies and HIV-1 Tat: interactive effects on glial [Ca²⁺]i, oxyradical and neuroinflammatory chemokine production and correlative neurotoxicity. Curr HIV Res (2014) 0.76
Nociceptin/orphanin FQ receptor-driven heterologous desensitization of the major HIV-1 co-receptor CXCR4. J Neuroimmune Pharmacol (2011) 0.76
Autoantibodies to the delta-opioid receptor function as opioid agonists and display immunomodulatory activity. J Neuroimmunol (2009) 0.75
Opioids and Viral Infections: A Double-Edged Sword. Front Microbiol (2016) 0.75
Activated niacin receptor HCA2 inhibits chemoattractant-mediated macrophage migration via Gβγ/PKC/ERK1/2 pathway and heterologous receptor desensitization. Sci Rep (2017) 0.75
Novel peptides based on HIV-1 gp120 sequence with homology to chemokines inhibit HIV infection in cell culture. PLoS One (2011) 0.75
Alterations of expression of inflammation/immune-related genes in the dorsal and ventral striatum of adult C57BL/6J mice following chronic oxycodone self-administration: a RNA sequencing study. Psychopharmacology (Berl) (2017) 0.75
A uniform proteomics MS/MS analysis platform utilizing open XML file formats. Mol Syst Biol (2005) 9.81
A higher-level phylogenetic classification of the Fungi. Mycol Res (2007) 7.93
The amsterdam declaration on fungal nomenclature. IMA Fungus (2011) 5.86
Toll-like receptor 4-dependent activation of dendritic cells by beta-defensin 2. Science (2002) 4.45
Mammalian defensins in immunity: more than just microbicidal. Trends Immunol (2002) 3.52
PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65. Open Biol (2012) 3.42
Transfusion of red blood cells after prolonged storage produces harmful effects that are mediated by iron and inflammation. Blood (2010) 3.03
Oncogenic Kras is required for both the initiation and maintenance of pancreatic cancer in mice. J Clin Invest (2012) 2.95
Interaction of TNF with TNF receptor type 2 promotes expansion and function of mouse CD4+CD25+ T regulatory cells. J Immunol (2007) 2.92
Multiple roles of antimicrobial defensins, cathelicidins, and eosinophil-derived neurotoxin in host defense. Annu Rev Immunol (2004) 2.72
Many chemokines including CCL20/MIP-3alpha display antimicrobial activity. J Leukoc Biol (2003) 2.62
High mobility group box-1 protein induces the migration and activation of human dendritic cells and acts as an alarmin. J Leukoc Biol (2006) 2.44
Engineering disulfide bridges to dissect antimicrobial and chemotactic activities of human beta-defensin 3. Proc Natl Acad Sci U S A (2003) 2.32
Alarmins: awaiting a clinical response. J Clin Invest (2012) 2.19
The association of NHERF adaptor proteins with g protein-coupled receptors and receptor tyrosine kinases. Annu Rev Physiol (2006) 2.18
Molecular phylogenetic diversity, multilocus haplotype nomenclature, and in vitro antifungal resistance within the Fusarium solani species complex. J Clin Microbiol (2008) 2.16
Cellular pharmacology studies of shikonin derivatives. Phytother Res (2002) 2.09
Rapamycin inhibits differentiation of Th17 cells and promotes generation of FoxP3+ T regulatory cells. Int Immunopharmacol (2007) 2.08
Eosinophil-derived neurotoxin acts as an alarmin to activate the TLR2-MyD88 signal pathway in dendritic cells and enhances Th2 immune responses. J Exp Med (2008) 2.04
Pharmacokinetics and pharmacodynamics of oral oxycodone in healthy human subjects: role of circulating active metabolites. Clin Pharmacol Ther (2006) 1.98
Reduced mitochondrial DNA copy number is correlated with tumor progression and prognosis in Chinese breast cancer patients. IUBMB Life (2007) 1.92
Comparison of pharmacological activities of three distinct kappa ligands (Salvinorin A, TRK-820 and 3FLB) on kappa opioid receptors in vitro and their antipruritic and antinociceptive activities in vivo. J Pharmacol Exp Ther (2004) 1.89
Trastuzumab-related cardiotoxicity among older patients with breast cancer. J Clin Oncol (2013) 1.89
Granulysin activates antigen-presenting cells through TLR4 and acts as an immune alarmin. Blood (2010) 1.85
Clinical and MRI characteristics of levamisole-induced leukoencephalopathy in 16 patients. J Neuroimaging (2009) 1.84
A proinflammatory chemokine, CCL3, sensitizes the heat- and capsaicin-gated ion channel TRPV1. Proc Natl Acad Sci U S A (2005) 1.82
Anthrax lethal toxin induces endothelial barrier dysfunction. Am J Pathol (2005) 1.81
Protein cross-linking analysis using mass spectrometry, isotope-coded cross-linkers, and integrated computational data processing. J Proteome Res (2006) 1.81
Synthesis and in vitro pharmacological studies of new C(2) modified salvinorin A analogues. Bioorg Med Chem Lett (2005) 1.79
Histidyl-tRNA synthetase and asparaginyl-tRNA synthetase, autoantigens in myositis, activate chemokine receptors on T lymphocytes and immature dendritic cells. J Exp Med (2002) 1.78
Mouse model of OPRM1 (A118G) polymorphism has sex-specific effects on drug-mediated behavior. Proc Natl Acad Sci U S A (2009) 1.76
Role of chemokines in angiogenesis: CXCL12/SDF-1 and CXCR4 interaction, a key regulator of endothelial cell responses. Microcirculation (2003) 1.71
Cutting edge: expression of TNFR2 defines a maximally suppressive subset of mouse CD4+CD25+FoxP3+ T regulatory cells: applicability to tumor-infiltrating T regulatory cells. J Immunol (2008) 1.71
Tumor-specific low molecular weight forms of cyclin E induce genomic instability and resistance to p21, p27, and antiestrogens in breast cancer. Cancer Res (2004) 1.70
Mouse cathelin-related antimicrobial peptide chemoattracts leukocytes using formyl peptide receptor-like 1/mouse formyl peptide receptor-like 2 as the receptor and acts as an immune adjuvant. J Immunol (2005) 1.62
Alarmins link neutrophils and dendritic cells. Trends Immunol (2009) 1.61
Synthesis and in vitro pharmacological evaluation of salvinorin A analogues modified at C(2). Bioorg Med Chem Lett (2005) 1.60
Human beta-defensin 2 and 3 and their mouse orthologs induce chemotaxis through interaction with CCR2. J Immunol (2010) 1.59
New concepts in the pathobiology of chronic obstructive pulmonary disease. Proc Am Thorac Soc (2008) 1.59
A haplotype map of genomic variations and genome-wide association studies of agronomic traits in foxtail millet (Setaria italica). Nat Genet (2013) 1.58
Synthesis and in vitro evaluation of salvinorin A analogues: effect of configuration at C(2) and substitution at C(18). Bioorg Med Chem Lett (2006) 1.55
Heterologous desensitization of opioid receptors by chemokines inhibits chemotaxis and enhances the perception of pain. Proc Natl Acad Sci U S A (2002) 1.55
mTOR complex component Rictor interacts with PKCzeta and regulates cancer cell metastasis. Cancer Res (2010) 1.54
High throughput proteome screening for biomarker detection. Mol Cell Proteomics (2005) 1.54
The structure of human macrophage inflammatory protein-3alpha /CCL20. Linking antimicrobial and CC chemokine receptor-6-binding activities with human beta-defensins. J Biol Chem (2002) 1.53
Internet-accessible DNA sequence database for identifying fusaria from human and animal infections. J Clin Microbiol (2010) 1.51
Mu-opioid modulation of HIV-1 coreceptor expression and HIV-1 replication. Virology (2003) 1.51
Meta-analysis confirms achieving pathological complete response after neoadjuvant chemotherapy predicts favourable prognosis for breast cancer patients. Eur J Cancer (2011) 1.51
Protein kinase C zeta is required for epidermal growth factor-induced chemotaxis of human breast cancer cells. Cancer Res (2005) 1.51
Stimulation of apical and basolateral VEGF-A and VEGF-C secretion by oxidative stress in polarized retinal pigment epithelial cells. Mol Vis (2006) 1.50
Are chemokines the third major system in the brain? J Leukoc Biol (2005) 1.50
Optimizing selective cerebral perfusion: deleterious effects of high perfusion pressures. J Thorac Cardiovasc Surg (2008) 1.48
Corra: Computational framework and tools for LC-MS discovery and targeted mass spectrometry-based proteomics. BMC Bioinformatics (2008) 1.48
Neuroprotective effect of recombinant human granulocyte colony-stimulating factor in transient focal ischemia of mice. J Cereb Blood Flow Metab (2006) 1.48
High severity and fatality of human infections with avian influenza A(H7N9) infection in China. Clin Infect Dis (2013) 1.47
Increased expression of multifunctional serine protease, HTRA1, in retinal pigment epithelium induces polypoidal choroidal vasculopathy in mice. Proc Natl Acad Sci U S A (2011) 1.45
Heterodimerization and cross-desensitization between the mu-opioid receptor and the chemokine CCR5 receptor. Eur J Pharmacol (2004) 1.45
Pertussis toxin by inducing IL-6 promotes the generation of IL-17-producing CD4 cells. J Immunol (2007) 1.45
UniPep--a database for human N-linked glycosites: a resource for biomarker discovery. Genome Biol (2006) 1.43
Evidence for altered activity of the IL-6 pathway in chronic rhinosinusitis with nasal polyps. J Allergy Clin Immunol (2010) 1.42
GRIM-19 inhibits the STAT3 signaling pathway and sensitizes gastric cancer cells to radiation. Gene (2012) 1.42
Defining forces that are associated with shoulder dystocia: the use of a mathematic dynamic computer model. Am J Obstet Gynecol (2003) 1.41
Prompt upper endoscopy is an appropriate initial management in uninvestigated chinese patients with typical reflux symptoms. Am J Gastroenterol (2010) 1.41
Does reduced IGF-1R signaling in Igf1r+/- mice alter aging? PLoS One (2011) 1.39
Ezrin-radixin-moesin-binding phosphoprotein-50/Na+/H+ exchanger regulatory factor (EBP50/NHERF) blocks U50,488H-induced down-regulation of the human kappa opioid receptor by enhancing its recycling rate. J Biol Chem (2002) 1.39
Viewing chemokines as a third major system of communication in the brain. AAPS J (2006) 1.39
Model test of anchoring effect on zonal disintegration in deep surrounding rock masses. ScientificWorldJournal (2013) 1.38
Sponge transgenic mouse model reveals important roles for the microRNA-183 (miR-183)/96/182 cluster in postmitotic photoreceptors of the retina. J Biol Chem (2011) 1.38
Mephedrone ('bath salt') elicits conditioned place preference and dopamine-sensitive motor activation. Drug Alcohol Depend (2012) 1.37
Co-expression of TNFR2 and CD25 identifies more of the functional CD4+FOXP3+ regulatory T cells in human peripheral blood. Eur J Immunol (2010) 1.37
Differential response of murine CD4+CD25+ and CD4+CD25- T cells to dexamethasone-induced cell death. Eur J Immunol (2004) 1.36
High resolution in vivo bioluminescent imaging for the study of bacterial tumour targeting. PLoS One (2012) 1.36
Tumor-associated macrophages recruit CCR6+ regulatory T cells and promote the development of colorectal cancer via enhancing CCL20 production in mice. PLoS One (2011) 1.36
Neutrophils promote experimental choroidal neovascularization. Mol Vis (2005) 1.35
Humanin, a newly identified neuroprotective factor, uses the G protein-coupled formylpeptide receptor-like-1 as a functional receptor. J Immunol (2004) 1.35
Social isolation alters neuroinflammatory response to stroke. Proc Natl Acad Sci U S A (2009) 1.34
Glucocorticoid amplifies IL-2-dependent expansion of functional FoxP3(+)CD4(+)CD25(+) T regulatory cells in vivo and enhances their capacity to suppress EAE. Eur J Immunol (2006) 1.34
Synthesis and in vitro pharmacological studies of C(4) modified salvinorin A analogues. Bioorg Med Chem Lett (2005) 1.34
Design, synthesis and biological evaluation of novel 4-thiazolidinones containing indolin-2-one moiety as potential antitumor agent. Eur J Med Chem (2011) 1.33
Human ribonuclease A superfamily members, eosinophil-derived neurotoxin and pancreatic ribonuclease, induce dendritic cell maturation and activation. J Immunol (2004) 1.33
Requirement of c-myb in T cell development and in mature T cell function. Proc Natl Acad Sci U S A (2004) 1.32
Identification and Biological Characterization of Mouse beta-defensin 14, the orthologue of human beta-defensin 3. J Biol Chem (2007) 1.32
The tumor-specific hyperactive forms of cyclin E are resistant to inhibition by p21 and p27. J Biol Chem (2005) 1.32
BALB/c mice have more CD4+CD25+ T regulatory cells and show greater susceptibility to suppression of their CD4+CD25- responder T cells than C57BL/6 mice. J Leukoc Biol (2005) 1.31