GTPgammaS incorporation in the rat brain: a study on mu-opioid receptors and CXCR4.

PubWeight™: 0.88‹?›

🔗 View Article (PMC 2689546)

Published in J Neuroimmune Pharmacol on October 25, 2007

Authors

Silvia Burbassi1, Vincent J Aloyo, Kenny J Simansky, Olimpia Meucci

Author Affiliations

1: Department of Pharmacology and Physiology, Drexel University College of Medicine, 245 North 15th Street (NCB 8804), Philadelphia, PA 19102, USA.

Articles cited by this

Function of the chemokine receptor CXCR4 in haematopoiesis and in cerebellar development. Nature (1998) 11.41

Impaired B-lymphopoiesis, myelopoiesis, and derailed cerebellar neuron migration in CXCR4- and SDF-1-deficient mice. Proc Natl Acad Sci U S A (1998) 7.69

A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development. J Exp Med (2006) 6.86

The neuropathogenesis of AIDS. Nat Rev Immunol (2005) 6.54

The chemokine SDF-1/CXCL12 binds to and signals through the orphan receptor RDC1 in T lymphocytes. J Biol Chem (2005) 5.45

HIV and antiretroviral therapy in the brain: neuronal injury and repair. Nat Rev Neurosci (2007) 3.73

Autoradiographic differentiation of mu, delta, and kappa opioid receptors in the rat forebrain and midbrain. J Neurosci (1987) 2.53

CXCR4 regulates interneuron migration in the developing neocortex. J Neurosci (2003) 2.44

A dual role for the SDF-1/CXCR4 chemokine receptor system in adult brain: isoform-selective regulation of SDF-1 expression modulates CXCR4-dependent neuronal plasticity and cerebral leukocyte recruitment after focal ischemia. J Neurosci (2002) 2.08

CXCR-4 (Fusin), a co-receptor for the type 1 human immunodeficiency virus (HIV-1), is expressed in the human brain in a variety of cell types, including microglia and neurons. Am J Pathol (1997) 2.00

Role of the alpha-chemokine stromal cell-derived factor (SDF-1) in the developing and mature central nervous system. Glia (2003) 1.94

In vitro autoradiography of receptor-activated G proteins in rat brain by agonist-stimulated guanylyl 5'-[gamma-[35S]thio]-triphosphate binding. Proc Natl Acad Sci U S A (1995) 1.88

Standard binding and functional assays related to medications development division testing for potential cocaine and opiate narcotic treatment medications. NIDA Res Monogr (1998) 1.86

Chemokine receptors are expressed widely by embryonic and adult neural progenitor cells. J Neurosci Res (2004) 1.81

Effects of chronic morphine administration on mu opioid receptor-stimulated [35S]GTPgammaS autoradiography in rat brain. J Neurosci (1996) 1.74

The chemokine stromal cell-derived factor-1 regulates the migration of sensory neuron progenitors. J Neurosci (2005) 1.69

Neuroanatomical distribution of CXCR4 in adult rat brain and its localization in cholinergic and dopaminergic neurons. Eur J Neurosci (2002) 1.52

Immunohistochemical analysis of CCR2, CCR3, CCR5, and CXCR4 in the human brain: potential mechanisms for HIV dementia. Exp Mol Pathol (2000) 1.48

Opiates as potential cofactors in progression of HIV-1 infections to AIDS. J Neuroimmunol (1998) 1.46

Evolution of the human immunodeficiency virus type 1 envelope during infection reveals molecular corollaries of specificity for coreceptor utilization and AIDS pathogenesis. J Virol (2000) 1.39

Selective inactivation of CCR5 and decreased infectivity of R5 HIV-1 strains mediated by opioid-induced heterologous desensitization. J Leukoc Biol (2003) 1.30

Highly regionalized distribution of stromal cell-derived factor-1/CXCL12 in adult rat brain: constitutive expression in cholinergic, dopaminergic and vasopressinergic neurons. Eur J Neurosci (2003) 1.30

Expression of the chemokine receptor Cxcr4 mRNA during mouse brain development. Brain Res Dev Brain Res (2004) 1.20

Principles: extending the utility of [35S]GTP gamma S binding assays. Trends Pharmacol Sci (2003) 1.20

Molecular targets of opiate drug abuse in neuroAIDS. Neurotox Res (2005) 1.16

AIDS and the brain: is there a chemokine connection? Trends Neurosci (1999) 1.14

Proteolytic processing of SDF-1alpha reveals a change in receptor specificity mediating HIV-associated neurodegeneration. Proc Natl Acad Sci U S A (2006) 1.12

Modulation of neuronal CXCR4 by the micro-opioid agonist DAMGO. J Neurovirol (2006) 1.11

Discrete mapping of brain Mu and delta opioid receptors using selective peptides: quantitative autoradiography, species differences and comparison with kappa receptors. Peptides (1989) 1.06

HIV and drug misuse in the Edinburgh cohort. J Acquir Immune Defic Syndr (2002) 1.00

Comparison of [Dmt1]DALDA and DAMGO in binding and G protein activation at mu, delta, and kappa opioid receptors. J Pharmacol Exp Ther (2003) 0.97

The chemokine SDF-1/CXCL12 modulates the firing pattern of vasopressin neurons and counteracts induced vasopressin release through CXCR4. Proc Natl Acad Sci U S A (2006) 0.97

Nociceptin (orphanin FQ): high-affinity and high-capacity binding site coupled to low-potency stimulation of guanylyl-5'-O-(gamma-thio)-triphosphate binding in rat brain membranes. J Pharmacol Exp Ther (1998) 0.96

Expression of SDF-1 and CXCR4 during reorganization of the postnatal dentate gyrus. Dev Neurosci (2007) 0.96

Mu opioid receptor coupling to Gi/o proteins increases during postnatal development in rat brain. J Pharmacol Exp Ther (2005) 0.95

Chemokines and their receptors in neurobiology: perspectives in physiology and homeostasis. J Neuroimmunol (2000) 0.95

Chemokine receptors in the brain: a developing story. J Comp Neurol (2003) 0.94

Relationship of mu opioid receptor binding to activation of G-proteins in specific rat brain regions. Biochem Pharmacol (2000) 0.88

Agonist-stimulated [35S]GTPgammaS autoradiography: optimization for high sensitivity. Eur J Pharmacol (2001) 0.87

Mu and Delta opioid receptors activate the same G proteins in human neuroblastoma SH-SY5Y cells. Br J Pharmacol (2002) 0.86

Articles by these authors

Site-specific phosphorylation of CXCR4 is dynamically regulated by multiple kinases and results in differential modulation of CXCR4 signaling. J Biol Chem (2010) 2.06

CX3CR1-fractalkine expression regulates cellular mechanisms involved in adhesion, migration, and survival of human prostate cancer cells. Cancer Res (2004) 1.55

The gamma-secretase-generated intracellular domain of beta-amyloid precursor protein binds Numb and inhibits Notch signaling. Proc Natl Acad Sci U S A (2002) 1.49

Activating parabrachial cannabinoid CB1 receptors selectively stimulates feeding of palatable foods in rats. J Neurosci (2008) 1.37

CX3CR1 is expressed by prostate epithelial cells and androgens regulate the levels of CX3CL1/fractalkine in the bone marrow: potential role in prostate cancer bone tropism. Cancer Res (2008) 1.15

Modulation of neuronal CXCR4 by the micro-opioid agonist DAMGO. J Neurovirol (2006) 1.11

An orexigenic role for mu-opioid receptors in the lateral parabrachial nucleus. Am J Physiol Regul Integr Comp Physiol (2003) 1.10

The chemokine receptor CXCR4 regulates cell-cycle proteins in neurons. J Neurovirol (2003) 1.10

Morphine increases brain levels of ferritin heavy chain leading to inhibition of CXCR4-mediated survival signaling in neurons. J Neurosci (2009) 1.10

Regulation of neuronal P53 activity by CXCR 4. Mol Cell Neurosci (2005) 1.10

Interactions between chemokines: regulation of fractalkine/CX3CL1 homeostasis by SDF/CXCL12 in cortical neurons. J Biol Chem (2010) 1.06

Apoptotic and antiapoptotic effects of CXCR4: is it a matter of intrinsic efficacy? Implications for HIV neuropathogenesis. AIDS Res Hum Retroviruses (2004) 1.06

Bone-metastatic potential of human prostate cancer cells correlates with Akt/PKB activation by alpha platelet-derived growth factor receptor. Oncogene (2005) 1.03

Role of the transcription factor E2F1 in CXCR4-mediated neurotoxicity and HIV neuropathology. Neurobiol Dis (2006) 0.99

Role of mu-opioids as cofactors in human immunodeficiency virus type 1 disease progression and neuropathogenesis. J Neurovirol (2011) 0.98

CXCR7 protein expression in human adult brain and differentiated neurons. PLoS One (2011) 0.96

Mu-opioid receptor cellular function in the nucleus accumbens is essential for hedonically driven eating. Eur J Neurosci (2006) 0.95

Human immunodeficiency virus gp120-induced apoptosis of human neuroblastoma cells in the absence of CXCR4 internalization. J Neurovirol (2006) 0.95

Chronic prevention of mu-opioid receptor (MOR) G-protein coupling in the pontine parabrachial nucleus persistently decreases consumption of standard but not palatable food. Psychopharmacology (Berl) (2006) 0.91

Bilaminar co-culture of primary rat cortical neurons and glia. J Vis Exp (2011) 0.91

The chemokine receptor CX₃CR1 is directly involved in the arrest of breast cancer cells to the skeleton. Breast Cancer Res (2011) 0.89

Modulation of dendritic cell maturation and function by the Tax protein of human T cell leukemia virus type 1. J Leukoc Biol (2007) 0.88

Neuropeptide FF exerts pro- and anti-opioid actions in the parabrachial nucleus to modulate food intake. Am J Physiol Regul Integr Comp Physiol (2003) 0.87

A naloxonazine sensitive (mu1 receptor) mechanism in the parabrachial nucleus modulates eating. Brain Res (2008) 0.86

Inhibiting parabrachial fatty acid amide hydrolase activity selectively increases the intake of palatable food via cannabinoid CB1 receptors. Am J Physiol Regul Integr Comp Physiol (2008) 0.85

CXCL12-mediated regulation of ANP32A/Lanp, a component of the inhibitor of histone acetyl transferase (INHAT) complex, in cortical neurons. J Neuroimmune Pharmacol (2010) 0.85

Pharmacological and behavioral characterization of the 5-HT2A receptor in C57BL/6N mice. Psychopharmacology (Berl) (2011) 0.85

Selective remodeling of rabbit frontal cortex: relationship between 5-HT2A receptor density and associative learning. Psychopharmacology (Berl) (2003) 0.84

Alterations of CXCR4 function in μ-opioid receptor-deficient glia. Eur J Neurosci (2010) 0.83

Regulation of cell cycle proteins by chemokine receptors: A novel pathway in human immunodeficiency virus neuropathogenesis? J Neurovirol (2004) 0.83

Intrahippocampal LSD accelerates learning and desensitizes the 5-HT(2A) receptor in the rabbit, Romano et al. Psychopharmacology (Berl) (2010) 0.82

Regulation of neuronal ferritin heavy chain, a new player in opiate-induced chemokine dysfunction. J Neuroimmune Pharmacol (2011) 0.81

Disruption of neuronal CXCR4 function by opioids: preliminary evidence of ferritin heavy chain as a potential etiological agent in neuroAIDS. J Neuroimmunol (2010) 0.81

The role of serotonin-2 (5-HT2) and dopamine receptors in the behavioral actions of the 5-HT2A/2C agonist, DOI, and putative 5-HT2C inverse agonist, SR46349B. Psychopharmacology (Berl) (2010) 0.81

Cardiac norepinephrine release: modulation by ovariectomy and estrogen. Exp Biol Med (Maywood) (2003) 0.80

Serotonin 5-HT2A receptors in the CA1 field of the hippocampus mediate head movements in the rabbit. Psychopharmacology (Berl) (2004) 0.80

The time-course for up- and down-regulation of the cortical 5-hydroxytryptamine (5-HT)2A receptor density predicts 5-HT2A receptor-mediated behavior in the rabbit. J Pharmacol Exp Ther (2007) 0.80

Effects of opiates and HIV proteins on neurons: the role of ferritin heavy chain and a potential for synergism. Curr HIV Res (2012) 0.79

Neuronal ferritin heavy chain and drug abuse affect HIV-associated cognitive dysfunction. J Clin Invest (2014) 0.79

A novel behavioral model that discriminates between 5-HT2A and 5-HT2C receptor activation. Pharmacol Biochem Behav (2002) 0.79

Serotonergic and dopaminergic distinctions in the behavioral pharmacology of (±)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Pharmacol Biochem Behav (2011) 0.78

A 5-HT2C agonist elicits hyperactivity and oral dyskinesia with hypophagia in rabbits. Physiol Behav (2004) 0.78

Multispectral imaging and automated laser capture microdissection of human cortical neurons: a quantitative study of CXCR4 expression. Methods Mol Biol (2013) 0.77

Identification of myristoylated alanine-rich C kinase substrate (MARCKS) in astrocytes. Front Biosci (2005) 0.77

Phospholipase C mediates (±)-1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI)-, but not lysergic acid diethylamide (LSD)-elicited head bobs in rabbit medial prefrontal cortex. Brain Res (2012) 0.77

Role of central 5-HT2 receptors in mediating head bobs and body shakes in the rabbit. Pharmacol Biochem Behav (2004) 0.77

The stereoisomer (+)-naloxone potentiates G-protein coupling and feeding associated with stimulation of mu opioid receptors in the parabrachial nucleus. J Psychopharmacol (2013) 0.77

Effect of μ-opioid agonist DAMGO on surface CXCR4 and HIV-1 replication in TF-1 human bone marrow progenitor cells. BMC Res Notes (2014) 0.76

Characterization of membrane-associated substrates of Ca2+-dependent kinases in astrocytes. Front Biosci (2005) 0.75