Systematic analysis of the TGF-beta/Smad signalling pathway in the rhabdomyosarcoma cell line RD.

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Published in Int J Exp Pathol on June 01, 2003

Authors

Hua Wang1, Guang-Hua Yang, Hong Bu, Qiao Zhou, Li-Xin Guo, Shou-Li Wang, Lv Ye

Author Affiliations

1: Department of Pathology, West China Hospital, Sichuan University, Chengdu, PR China. hxwanghua@21cn.com

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TGF-beta signalling from cell membrane to nucleus through SMAD proteins. Nature (1997) 15.75

TGFbeta signaling in growth control, cancer, and heritable disorders. Cell (2000) 12.38

The transforming growth factor-beta family. Annu Rev Cell Biol (1990) 10.62

The myoD gene family: nodal point during specification of the muscle cell lineage. Science (1991) 9.53

Controlling TGF-beta signaling. Genes Dev (2000) 8.13

Identification of Smad7, a TGFbeta-inducible antagonist of TGF-beta signalling. Nature (1997) 7.69

The MAD-related protein Smad7 associates with the TGFbeta receptor and functions as an antagonist of TGFbeta signaling. Cell (1997) 6.34

Smads: transcriptional activators of TGF-beta responses. Cell (1998) 5.33

Cultivation in vitro of cells derived from a human rhabdomyosarcoma. Cancer (1969) 4.99

TGF-beta receptor-mediated signalling through Smad2, Smad3 and Smad4. EMBO J (1997) 4.48

Type beta transforming growth factor is an inhibitor of myogenic differentiation. Proc Natl Acad Sci U S A (1986) 3.83

Physiological actions and clinical applications of transforming growth factor-beta (TGF-beta). Growth Factors (1993) 3.43

Biology and therapy of pediatric rhabdomyosarcoma. J Clin Oncol (1995) 3.00

Extension of the life-span of human endothelial cells by an interleukin-1 alpha antisense oligomer. Science (1990) 2.59

Insulin-like growth factor II acts as an autocrine growth and motility factor in human rhabdomyosarcoma tumors. Cell Growth Differ (1990) 2.24

Deficiency in rhabdomyosarcomas of a factor required for MyoD activity and myogenesis. Science (1993) 1.99

Mads and Smads in TGF beta signalling. Curr Opin Cell Biol (1998) 1.57

The nuclear import function of Smad2 is masked by SARA and unmasked by TGFbeta-dependent phosphorylation. Nat Cell Biol (2000) 1.55

Transforming growth factor beta represses the actions of myogenin through a mechanism independent of DNA binding. Proc Natl Acad Sci U S A (1991) 1.53

Ligand-independent activation of transforming growth factor (TGF) beta signaling pathways by heteromeric cytoplasmic domains of TGF-beta receptors. J Biol Chem (1996) 1.47

Basic fibroblast growth factor in human rhabdomyosarcoma cells: implications for the proliferation and neovascularization of myoblast-derived tumors. Proc Natl Acad Sci U S A (1987) 1.38

Regulation of intracellular dynamics of Smad4 by its leucine-rich nuclear export signal. EMBO Rep (2000) 1.29

Specific expression of insulin-like growth factor-II in rhabdomyosarcoma tumor cells. Am J Clin Pathol (1994) 1.17

Genetic change in transforming growth factor beta (TGF-beta) receptor type I gene correlates with insensitivity to TGF-beta 1 in human prostate cancer cells. Cancer Res (1996) 1.12

TGF-beta autocrine loop regulates cell growth and myogenic differentiation in human rhabdomyosarcoma cells. FASEB J (2000) 0.95

Soft tissue tumours in childhood. Histopathology (1993) 0.90

Use of the MTT assay in adult ventricular cardiomyocytes to assess viability: effects of adenosine and potassium on cellular survival. J Mol Cell Cardiol (1997) 0.89

Antisense epidermal growth factor receptor transfection impairs the proliferative ability of human rhabdomyosarcoma cells. Cancer Res (1996) 0.88

Redundancy of autocrine loops in human rhabdomyosarcoma cells: induction of differentiation by suramin. Br J Cancer (1995) 0.85

The molecular biology of childhood rhabdomyosarcoma. Semin Diagn Pathol (1994) 0.84

Effect of suppression of TGF-beta1 expression on cell-cycle and gene expression of beta-1,4-galactosyltransferase 1 in human hepatocarcinoma cells. Biochem Biophys Res Commun (2000) 0.78

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