Published in PLoS One on November 30, 2010
Reprogramming cardiomyocyte mechanosensing by crosstalk between integrins and hyaluronic acid receptors. J Biomech (2011) 1.00
Hyaluronan regulates cell behavior: a potential niche matrix for stem cells. Biochem Res Int (2012) 0.94
Amniotic fluid stem cells morph into a cardiovascular lineage: analysis of a chemically induced cardiac and vascular commitment. Drug Des Devel Ther (2013) 0.82
Neurological morphofunctional differentiation induced by REAC technology in PC12. A neuro protective model for Parkinson's disease. Sci Rep (2015) 0.80
Prometheus's heart: what lies beneath. J Cell Mol Med (2012) 0.80
Local activation of cardiac stem cells for post-myocardial infarction cardiac repair. J Cell Mol Med (2012) 0.79
The functional diversity of essential genes required for mammalian cardiac development. Genesis (2014) 0.79
REAC technology and hyaluron synthase 2, an interesting network to slow down stem cell senescence. Sci Rep (2016) 0.77
What Can be Learned from the Time Course of Changes in Low-Frequency Stimulated Muscle? Eur J Transl Myol (2017) 0.75
A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res (2001) 124.61
Controlling TGF-beta signaling. Genes Dev (2000) 8.13
Embryo-derived stem cells: of mice and men. Annu Rev Cell Dev Biol (2001) 6.76
Mouse GATA-4: a retinoic acid-inducible GATA-binding transcription factor expressed in endodermally derived tissues and heart. Mol Cell Biol (1993) 4.13
The gene tinman is required for specification of the heart and visceral muscles in Drosophila. Development (1993) 4.11
Smad regulation in TGF-beta signal transduction. J Cell Sci (2001) 3.99
Nkx-2.5: a novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants. Development (1993) 3.94
tinman and bagpipe: two homeo box genes that determine cell fates in the dorsal mesoderm of Drosophila. Genes Dev (1993) 3.90
NK-2 homeobox genes and heart development. Dev Biol (1996) 3.55
Smad6 inhibits BMP/Smad1 signaling by specifically competing with the Smad4 tumor suppressor. Genes Dev (1998) 3.16
Smads as transcriptional co-modulators. Curr Opin Cell Biol (2000) 2.92
Control of early cardiac-specific transcription of Nkx2-5 by a GATA-dependent enhancer. Development (1999) 2.24
Building the heart piece by piece: modularity of cis-elements regulating Nkx2-5 transcription. Development (1999) 1.88
ATP-driven chromatin remodeling activity and histone acetyltransferases act sequentially during transactivation by RAR/RXR In vitro. Mol Cell (2000) 1.83
Smad proteins act in combination with synergistic and antagonistic regulators to target Dpp responses to the Drosophila mesoderm. Genes Dev (1998) 1.77
A new homeobox-containing gene, msh-2, is transiently expressed early during mesoderm formation of Drosophila. Development (1990) 1.74
Cardiac-specific activity of an Nkx2-5 enhancer requires an evolutionarily conserved Smad binding site. Dev Biol (2002) 1.72
The cardiac determination factor, Nkx2-5, is activated by mutual cofactors GATA-4 and Smad1/4 via a novel upstream enhancer. J Biol Chem (2003) 1.58
A GATA-dependent nkx-2.5 regulatory element activates early cardiac gene expression in transgenic mice. Development (1998) 1.45
Hyaluronan mixed esters of butyric and retinoic Acid drive cardiac and endothelial fate in term placenta human mesenchymal stem cells and enhance cardiac repair in infarcted rat hearts. J Biol Chem (2007) 1.35
Promoting bone morphogenetic protein signaling through negative regulation of inhibitory Smads. EMBO J (2001) 1.34
Identification of upstream regulatory regions in the heart-expressed homeobox gene Nkx2-5. Development (1999) 1.22
Smads, TAK1, and their common target ATF-2 play a critical role in cardiomyocyte differentiation. J Cell Biol (2001) 1.20
Myocardial smad4 is essential for cardiogenesis in mouse embryos. Circ Res (2007) 1.19
Smad7 is required for the development and function of the heart. J Biol Chem (2008) 1.18
Retinoic acids potentiate BMP9-induced osteogenic differentiation of mesenchymal progenitor cells. PLoS One (2010) 1.17
Regulation of TGF-beta signalling by protein phosphatases. Biochem J (2010) 1.08
Complex modular cis-acting elements regulate expression of the cardiac specifying homeobox gene Csx/Nkx2.5. Development (1999) 1.06
Opioid peptide gene expression primes cardiogenesis in embryonal pluripotent stem cells. Circ Res (2000) 0.98
Butyric and retinoic mixed ester of hyaluronan. A novel differentiating glycoconjugate affording a high throughput of cardiogenesis in embryonic stem cells. J Biol Chem (2004) 0.96
Retinoic acid stimulates chondrocyte differentiation and enhances bone morphogenetic protein effects through induction of Smad1 and Smad5. Endocrinology (2003) 0.95
Dynorphin B is an agonist of nuclear opioid receptors coupling nuclear protein kinase C activation to the transcription of cardiogenic genes in GTR1 embryonic stem cells. Circ Res (2003) 0.94
Molecular basis of sodium butyrate-dependent proapoptotic activity in cancer cells. Adv Med Sci (2007) 0.91
Transforming growth factor-beta1 downregulation of Smad1 gene expression in rat hepatic stellate cells. Am J Physiol Gastrointest Liver Physiol (2003) 0.91
The TGFbeta/Smad 3-signaling pathway is involved in butyrate-mediated vitamin D receptor (VDR)-expression. J Cell Biochem (2007) 0.86
Protein kinase C signaling transduces endorphin-primed cardiogenesis in GTR1 embryonic stem cells. Circ Res (2003) 0.85
Hyaluronan mixed esters of butyric and retinoic acid affording myocardial survival and repair without stem cell transplantation. J Biol Chem (2010) 0.83
Suppression of ES cell differentiation by retinol (vitamin A) via the overexpression of Nanog. Differentiation (2007) 0.83
Beta-hydroxybutyrate-induced growth inhibition and collagen production in HK-2 cells are dependent on TGF-beta and Smad3. Kidney Int (2003) 0.82
Systematic analysis of the TGF-beta/Smad signalling pathway in the rhabdomyosarcoma cell line RD. Int J Exp Pathol (2003) 0.80
B-type natriuretic peptide attenuates cardiac hypertrophy via the transforming growth factor-ß1/smad7 pathway in vivo and in vitro. Clin Exp Pharmacol Physiol (2009) 0.80
Modification of TGF-beta1 signaling pathway during NB4 cells differentiation by all-trans retinoid acid induction. Int J Hematol (2009) 0.79
All-trans-retinoic acid alters Smads expression in embryonic neural tissue of mice. J Appl Toxicol (2009) 0.77
Creating prodynorphin-expressing stem cells alerted for a high-throughput of cardiogenic commitment. Regen Med (2007) 0.76
Short QT Syndrome: a familial cause of sudden death. Circulation (2003) 4.23
Sudden death associated with short-QT syndrome linked to mutations in HERG. Circulation (2003) 3.68
Activation and function of cyclin T-Cdk9 (positive transcription elongation factor-b) in cardiac muscle-cell hypertrophy. Nat Med (2002) 2.82
Congenital short QT syndrome and implantable cardioverter defibrillator treatment: inherent risk for inappropriate shock delivery. J Cardiovasc Electrophysiol (2003) 2.14
Safety and efficacy of cryoablation of accessory pathways adjacent to the normal conduction system. J Cardiovasc Electrophysiol (2003) 1.91
Short QT syndrome: pharmacological treatment. J Am Coll Cardiol (2004) 1.87
Mutations of hMLH1 and hMSH2 in patients with suspected hereditary nonpolyposis colorectal cancer: correlation with microsatellite instability and abnormalities of mismatch repair protein expression. J Clin Oncol (2002) 1.75
Glucose-6-phosphate dehydrogenase-derived NADPH fuels superoxide production in the failing heart. J Mol Cell Cardiol (2006) 1.73
Term Amniotic membrane is a high throughput source for multipotent Mesenchymal Stem Cells with the ability to differentiate into endothelial cells in vitro. BMC Dev Biol (2007) 1.71
Risk stratification of the patients with Brugada type electrocardiogram: a community-based prospective study. Europace (2009) 1.66
From G0 to S phase: a view of the roles played by the retinoblastoma (Rb) family members in the Rb-E2F pathway. J Cell Biochem (2007) 1.65
Genetic basis of pulmonary arterial hypertension: current understanding and future directions. J Am Coll Cardiol (2004) 1.53
Paradoxical downregulation of the glucose oxidation pathway despite enhanced flux in severe heart failure. J Mol Cell Cardiol (2004) 1.49
Potential role of HER2-overexpressing exosomes in countering trastuzumab-based therapy. J Cell Physiol (2012) 1.45
Cardiomyocyte VEGFR-1 activation by VEGF-B induces compensatory hypertrophy and preserves cardiac function after myocardial infarction. FASEB J (2009) 1.39
Hyaluronan mixed esters of butyric and retinoic Acid drive cardiac and endothelial fate in term placenta human mesenchymal stem cells and enhance cardiac repair in infarcted rat hearts. J Biol Chem (2007) 1.35
Dexamethasone plus rituximab yields higher sustained response rates than dexamethasone monotherapy in adults with primary immune thrombocytopenia. Blood (2010) 1.34
Activation of MyoD-dependent transcription by cdk9/cyclin T2. Oncogene (2002) 1.33
Importance of Ezh2 polycomb protein in tumorigenesis process interfering with the pathway of growth suppressive key elements. J Cell Physiol (2008) 1.31
Anatomical variability of the lateral femoral cutaneous nerve: findings from a surgical series. Clin Anat (2009) 1.30
Pectin methylesterase is induced in Arabidopsis upon infection and is necessary for a successful colonization by necrotrophic pathogens. Mol Plant Microbe Interact (2011) 1.28
Transgenic expression of a fungal endo-polygalacturonase increases plant resistance to pathogens and reduces auxin sensitivity. Plant Physiol (2007) 1.28
Assessment of real-time myocardial uptake and enzymatic conversion of hyperpolarized [1-¹³C]pyruvate in pigs using slice selective magnetic resonance spectroscopy. Contrast Media Mol Imaging (2012) 1.20
The ectopic expression of a pectin methyl esterase inhibitor increases pectin methyl esterification and limits fungal diseases in wheat. Mol Plant Microbe Interact (2011) 1.16
Ezh2 reduces the ability of HDAC1-dependent pRb2/p130 transcriptional repression of cyclin A. Oncogene (2004) 1.16
Early detection of acute lung injury uncoupled to hypoxemia in pigs using ultrasound lung comets. Crit Care Med (2007) 1.14
Ferritin as a reporter gene for in vivo tracking of stem cells by 1.5-T cardiac MRI in a rat model of myocardial infarction. Am J Physiol Heart Circ Physiol (2011) 1.11
CDK9/CYCLIN T1 expression during normal lymphoid differentiation and malignant transformation. J Pathol (2004) 1.11
Future perspectives for the treatment of pulmonary arterial hypertension. J Am Coll Cardiol (2009) 1.08
Radiofrequency energy loop primes cardiac, neuronal, and skeletal muscle differentiation in mouse embryonic stem cells: a new tool for improving tissue regeneration. Cell Transplant (2011) 1.06
Deacetylase recruitment by the C/H3 domain of the acetyltransferase p300. Oncogene (2004) 1.06
Targeted biocompatible nanoparticles for the delivery of (-)-epigallocatechin 3-gallate to prostate cancer cells. J Med Chem (2011) 1.05
Histone deacetylase inhibitors in the treatment of hematological malignancies and solid tumors. J Biomed Biotechnol (2010) 1.03
A new nonenzymatic method and device to obtain a fat tissue derivative highly enriched in pericyte-like elements by mild mechanical forces from human lipoaspirates. Cell Transplant (2012) 1.03
Arabidopsis and Brachypodium distachyon transgenic plants expressing Aspergillus nidulans acetylesterases have decreased degree of polysaccharide acetylation and increased resistance to pathogens. Plant Physiol (2013) 1.02
Sustained NF-kappaB activation produces a short-term cell proliferation block in conjunction with repressing effectors of cell cycle progression controlled by E2F or FoxM1. J Cell Physiol (2009) 1.01
Silencing of RB1 but not of RB2/P130 induces cellular senescence and impairs the differentiation potential of human mesenchymal stem cells. Cell Mol Life Sci (2013) 0.99
Mild exercise training, cardioprotection and stress genes profile. Eur J Appl Physiol (2007) 0.98
Distinct cardiac and renal effects of ETA receptor antagonist and ACE inhibitor in experimental type 2 diabetes. Am J Physiol Renal Physiol (2011) 0.98
Development of polymeric microbubbles targeted to prostate-specific membrane antigen as prototype of novel ultrasound contrast agents. Mol Pharm (2011) 0.98
Radio electric conveyed fields directly reprogram human dermal skin fibroblasts toward cardiac, neuronal, and skeletal muscle-like lineages. Cell Transplant (2012) 0.97
Assessing the pathogenicity of MLH1 missense mutations in patients with suspected hereditary nonpolyposis colorectal cancer: correlation with clinical, genetic and functional features. Eur J Hum Genet (2006) 0.96
Butyric and retinoic mixed ester of hyaluronan. A novel differentiating glycoconjugate affording a high throughput of cardiogenesis in embryonic stem cells. J Biol Chem (2004) 0.96
Relation of QRS duration to mortality in a community-based cohort with hypertrophic cardiomyopathy. Am J Cardiol (2007) 0.96
Physical interaction between pRb and cdk9/cyclinT2 complex. Oncogene (2002) 0.95
MyoD recruits the cdk9/cyclin T2 complex on myogenic-genes regulatory regions. J Cell Physiol (2006) 0.95
Mesenchymal stem cells and islet cotransplantation in diabetic rats: improved islet graft revascularization and function by human adipose tissue-derived stem cells preconditioned with natural molecules. Cell Transplant (2012) 0.94
Patients with differentiated thyroid cancer who underwent radioiodine thyroid remnant ablation with low-activity ¹³¹I after either recombinant human TSH or thyroid hormone therapy withdrawal showed the same outcome after a 10-year follow-up. J Clin Endocrinol Metab (2013) 0.94
The ablation of EZH2 uncovers its crucial role in rhabdomyosarcoma formation. Cell Cycle (2012) 0.94
PKC/Raf/MEK/ERK signaling pathway modulates native-LDL-induced E2F-1 gene expression and endothelial cell proliferation. Cardiovasc Res (2003) 0.94
X chromosome and ovarian failure. Semin Reprod Med (2007) 0.93
Protein oxidation seems to be linked to constitutive autophagy: a sex study. Life Sci (2013) 0.93
A functional pectin methylesterase inhibitor protein (SolyPMEI) is expressed during tomato fruit ripening and interacts with PME-1. Plant Mol Biol (2012) 0.92
Cell wall integrity: targeted post-synthetic modifications to reveal its role in plant growth and defense against pathogens. Plant Signal Behav (2013) 0.92
Splenectomy as a curative treatment for immune thrombocytopenia: a retrospective analysis of 233 patients with a minimum follow up of 10 years. Haematologica (2012) 0.91
Chronic activation of peroxisome proliferator-activated receptor-alpha with fenofibrate prevents alterations in cardiac metabolic phenotype without changing the onset of decompensation in pacing-induced heart failure. J Pharmacol Exp Ther (2007) 0.91
Osteopontin controls endothelial cell migration in vitro and in excised human valvular tissue from patients with calcific aortic stenosis and controls. J Cell Physiol (2011) 0.91
Mesenchymal stem cells in renal function recovery after acute kidney injury: use of a differentiating agent in a rat model. Cell Transplant (2010) 0.90
Acute hemodynamic effect of left ventricular endocardial pacing in cardiac resynchronization therapy: assessment by pressure-volume loops. Circ Arrhythm Electrophysiol (2012) 0.90
Control of autocrine and paracrine myocardial signals: an emerging therapeutic strategy in heart failure. Heart Fail Rev (2010) 0.90
Expression of C-type natriuretic peptide and of its receptor NPR-B in normal and failing heart. Peptides (2008) 0.90
Cell wall traits as potential resources to improve resistance of durum wheat against Fusarium graminearum. BMC Plant Biol (2015) 0.89
Characteristics of maxillofacial trauma in females: a retrospective analysis of 367 patients. J Craniomaxillofac Surg (2009) 0.89
Frequent loss of pRb2/p130 in human ovarian carcinoma. Clin Cancer Res (2004) 0.89
The anti-metastatic agent imidazolium trans-imidazoledimethylsulfoxide-tetrachlororuthenate induces endothelial cell apoptosis by inhibiting the mitogen-activated protein kinase/extracellular signal-regulated kinase signaling pathway. Arch Biochem Biophys (2002) 0.89
CTCF and BORIS regulate Rb2/p130 gene transcription: a novel mechanism and a new paradigm for understanding the biology of lung cancer. Mol Cancer Res (2011) 0.89
Inhibition of hepatocellular carcinomas in vitro and hepatic metastases in vivo in mice by the histone deacetylase inhibitor HA-But. Clin Cancer Res (2004) 0.89
Cryoenergy catheter ablation: a new technique for treatment of permanent junctional reciprocating tachycardia in children. J Cardiovasc Electrophysiol (2004) 0.88
Glucose 6-phosphate dehydrogenase deficiency increases redox stress and moderately accelerates the development of heart failure. Circ Heart Fail (2012) 0.88
How the signal-to-noise ratio influences hyperpolarized 13C dynamic MRS data fitting and parameter estimation. NMR Biomed (2011) 0.88
Atrial fibrillation in a large population with Brugada electrocardiographic pattern: prevalence, management, and correlation with prognosis. Heart Rhythm (2014) 0.88
Early subclinical increase in pulmonary water content in athletes performing sustained heavy exercise at sea level: ultrasound lung comet-tail evidence. Am J Physiol Heart Circ Physiol (2011) 0.87
Placental stem cells pre-treated with a hyaluronan mixed ester of butyric and retinoic acid to cure infarcted pig hearts: a multimodal study. Cardiovasc Res (2011) 0.87
Shed HER2 extracellular domain in HER2-mediated tumor growth and in trastuzumab susceptibility. J Cell Physiol (2010) 0.87
Inhibition of the MEK/ERK signaling pathway by the novel antimetastatic agent NAMI-A down regulates c-myc gene expression and endothelial cell proliferation. Eur J Biochem (2002) 0.87
Radioelectric asymmetric conveyed fields and human adipose-derived stem cells obtained with a nonenzymatic method and device: a novel approach to multipotency. Cell Transplant (2013) 0.87
Anti-senescence efficacy of radio-electric asymmetric conveyer technology. Age (Dordr) (2013) 0.86
A susceptibility gene for premature ovarian failure (POF) maps to proximal Xq28. Eur J Hum Genet (2004) 0.86
Regenerative treatment using a radioelectric asymmetric conveyor as a novel tool in antiaging medicine: an in vitro beta-galactosidase study. Clin Interv Aging (2012) 0.86