Published in Development on November 01, 2003
Retinoic acid from the meninges regulates cortical neuron generation. Cell (2009) 2.46
The FaceBase Consortium: a comprehensive program to facilitate craniofacial research. Dev Biol (2011) 2.16
Palatogenesis: morphogenetic and molecular mechanisms of secondary palate development. Development (2012) 2.01
The human calvaria: a review of embryology, anatomy, pathology, and molecular development. Childs Nerv Syst (2011) 1.72
Ectodermal Smad4 and p38 MAPK are functionally redundant in mediating TGF-beta/BMP signaling during tooth and palate development. Dev Cell (2008) 1.61
Regional regulation of palatal growth and patterning along the anterior-posterior axis in mice. J Anat (2005) 1.60
Smad2 and myocardin-related transcription factor B cooperatively regulate vascular smooth muscle differentiation from neural crest cells. Circ Res (2013) 1.58
Two developmental modules establish 3D beak-shape variation in Darwin's finches. Proc Natl Acad Sci U S A (2011) 1.55
TGF-beta signaling is essential for joint morphogenesis. J Cell Biol (2007) 1.51
Epithelial and ectomesenchymal role of the type I TGF-beta receptor ALK5 during facial morphogenesis and palatal fusion. Dev Biol (2006) 1.50
Inactivation of TGFbeta signaling in neural crest stem cells leads to multiple defects reminiscent of DiGeorge syndrome. Genes Dev (2005) 1.50
Primary cellular meningeal defects cause neocortical dysplasia and dyslamination. Ann Neurol (2010) 1.48
Prdm16 is required for normal palatogenesis in mice. Hum Mol Genet (2009) 1.46
Integration of IRF6 and Jagged2 signalling is essential for controlling palatal adhesion and fusion competence. Hum Mol Genet (2009) 1.45
Variation in WNT genes is associated with non-syndromic cleft lip with or without cleft palate. Hum Mol Genet (2008) 1.39
Wnt5a can both activate and repress Wnt/β-catenin signaling during mouse embryonic development. Dev Biol (2012) 1.39
Cortical dysplasia and skull defects in mice with a Foxc1 allele reveal the role of meningeal differentiation in regulating cortical development. Proc Natl Acad Sci U S A (2007) 1.39
Modulation of noncanonical TGF-β signaling prevents cleft palate in Tgfbr2 mutant mice. J Clin Invest (2012) 1.37
The role of TGF-beta signaling in regulating chondrogenesis and osteogenesis during mandibular development. Dev Biol (2006) 1.36
Modulation of BMP signaling by Noggin is required for the maintenance of palatal epithelial integrity during palatogenesis. Dev Biol (2010) 1.34
Current perspectives of the signaling pathways directing neural crest induction. Cell Mol Life Sci (2012) 1.30
Hand2 is required in the epithelium for palatogenesis in mice. Dev Biol (2009) 1.28
Concerted action of Msx1 and Msx2 in regulating cranial neural crest cell differentiation during frontal bone development. Mech Dev (2007) 1.22
Defective ALK5 signaling in the neural crest leads to increased postmigratory neural crest cell apoptosis and severe outflow tract defects. BMC Dev Biol (2006) 1.20
The Mn1 transcription factor acts upstream of Tbx22 and preferentially regulates posterior palate growth in mice. Development (2008) 1.16
The widely used Wnt1-Cre transgene causes developmental phenotypes by ectopic activation of Wnt signaling. Dev Biol (2013) 1.16
TGF-beta mediated FGF10 signaling in cranial neural crest cells controls development of myogenic progenitor cells through tissue-tissue interactions during tongue morphogenesis. Dev Biol (2010) 1.15
BMP signaling regulates sympathetic nervous system development through Smad4-dependent and -independent pathways. Development (2009) 1.15
Transforming growth factor-beta regulates basal transcriptional regulatory machinery to control cell proliferation and differentiation in cranial neural crest-derived osteoprogenitor cells. J Biol Chem (2009) 1.14
Fibroblast growth factor 9 (FGF9)-pituitary homeobox 2 (PITX2) pathway mediates transforming growth factor β (TGFβ) signaling to regulate cell proliferation in palatal mesenchyme during mouse palatogenesis. J Biol Chem (2011) 1.10
TGF-beta mediated Dlx5 signaling plays a crucial role in osteo-chondroprogenitor cell lineage determination during mandible development. Dev Biol (2008) 1.07
Overexpression of Spry1 in chondrocytes causes attenuated FGFR ubiquitination and sustained ERK activation resulting in chondrodysplasia. Dev Biol (2008) 1.04
Tgfbr2 is required for development of the skull vault. Dev Biol (2009) 1.04
The mechanism of TGF-β signaling during palate development. Oral Dis (2011) 1.04
Hand in glove: brain and skull in development and dysmorphogenesis. Acta Neuropathol (2013) 1.04
Cell autonomous requirement for TGF-beta signaling during odontoblast differentiation and dentin matrix formation. Mech Dev (2007) 1.04
Smad4-Irf6 genetic interaction and TGFβ-mediated IRF6 signaling cascade are crucial for palatal fusion in mice. Development (2013) 1.03
Indirect modulation of Shh signaling by Dlx5 affects the oral-nasal patterning of palate and rescues cleft palate in Msx1-null mice. Development (2009) 1.02
Insights into neural crest development and evolution from genomic analysis. Genome Res (2013) 1.02
Wnt5a regulates growth, patterning, and odontoblast differentiation of developing mouse tooth. Dev Dyn (2011) 1.00
Tbx1 is necessary for palatal elongation and elevation. Mech Dev (2010) 0.99
Axin2 regulates chondrocyte maturation and axial skeletal development. J Orthop Res (2010) 0.97
Disruption of Smad4 in neural crest cells leads to mid-gestation death with pharyngeal arch, craniofacial and cardiac defects. Dev Biol (2008) 0.96
Mice with an anterior cleft of the palate survive neonatal lethality. Dev Dyn (2008) 0.95
Clinical features in a family with an R460H mutation in transforming growth factor beta receptor 2 gene. J Med Genet (2006) 0.95
A healthy tension in translational research. J Clin Invest (2014) 0.95
Protein tyrosine phosphatase activity in the neural crest is essential for normal heart and skull development. Proc Natl Acad Sci U S A (2009) 0.94
Enhanced BMP signaling prevents degeneration and leads to endochondral ossification of Meckel's cartilage in mice. Dev Biol (2013) 0.94
Inactivation of Tgfbr2 in Osterix-Cre expressing dental mesenchyme disrupts molar root formation. Dev Biol (2013) 0.93
Pax9 regulates a molecular network involving Bmp4, Fgf10, Shh signaling and the Osr2 transcription factor to control palate morphogenesis. Development (2013) 0.92
Type 1 fibroblast growth factor receptor in cranial neural crest cell-derived mesenchyme is required for palatogenesis. J Biol Chem (2013) 0.90
Impaired meningeal development in association with apical expansion of calvarial bone osteogenesis in the Foxc1 mutant. J Anat (2008) 0.90
Conditional expression of Spry1 in neural crest causes craniofacial and cardiac defects. BMC Dev Biol (2010) 0.89
TGF-beta type I receptor Alk5 regulates tooth initiation and mandible patterning in a type II receptor-independent manner. Dev Biol (2008) 0.89
TGF-β type II receptor/MCP-5 axis: at the crossroad between joint and growth plate development. Dev Cell (2012) 0.89
TGF-beta mediated Msx2 expression controls occipital somites-derived caudal region of skull development. Dev Biol (2007) 0.89
TGF-β-activated kinase 1 (Tak1) mediates agonist-induced Smad activation and linker region phosphorylation in embryonic craniofacial neural crest-derived cells. J Biol Chem (2013) 0.87
Trigenic neural crest-restricted Smad7 over-expression results in congenital craniofacial and cardiovascular defects. Dev Biol (2010) 0.87
Rbms3 functions in craniofacial development by posttranscriptionally modulating TGF-β signaling. J Cell Biol (2012) 0.86
The non-canonical BMP and Wnt/β-catenin signaling pathways orchestrate early tooth development. Development (2014) 0.86
Molecular signaling along the anterior-posterior axis of early palate development. Front Physiol (2013) 0.86
Roles of BMP signaling pathway in lip and palate development. Front Oral Biol (2012) 0.86
CTGF mediates Smad-dependent transforming growth factor β signaling to regulate mesenchymal cell proliferation during palate development. Mol Cell Biol (2013) 0.85
Genetic disruption of the sh3pxd2a gene reveals an essential role in mouse development and the existence of a novel isoform of tks5. PLoS One (2014) 0.84
Augmented BMPRIA-mediated BMP signaling in cranial neural crest lineage leads to cleft palate formation and delayed tooth differentiation. PLoS One (2013) 0.84
Murine craniofacial development requires Hdac3-mediated repression of Msx gene expression. Dev Biol (2013) 0.84
PRDM Proteins: Molecular Mechanisms in Signal Transduction and Transcriptional Regulation. Biology (Basel) (2013) 0.83
Collagen XXIV (Col24α1) promotes osteoblastic differentiation and mineralization through TGF-β/Smads signaling pathway. Int J Biol Sci (2012) 0.83
Recycling signals in the neural crest. J Biol (2005) 0.83
Requirement for Dlgh-1 in planar cell polarity and skeletogenesis during vertebrate development. PLoS One (2013) 0.83
Mesodermal expression of integrin α5β1 regulates neural crest development and cardiovascular morphogenesis. Dev Biol (2014) 0.83
Signaling networks in palate development. Wiley Interdiscip Rev Syst Biol Med (2014) 0.83
Alk5-mediated transforming growth factor β signaling acts upstream of fibroblast growth factor 10 to regulate the proliferation and maintenance of dental epithelial stem cells. Mol Cell Biol (2011) 0.82
Endothelial cells regulate neural crest and second heart field morphogenesis. Biol Open (2014) 0.82
The role of vertebrate models in understanding craniosynostosis. Childs Nerv Syst (2012) 0.82
Cranial neural crest cell contribution to craniofacial formation, pathology, and future directions in tissue engineering. Birth Defects Res C Embryo Today (2014) 0.81
Identification of candidate downstream targets of TGFβ signaling during palate development by genome-wide transcript profiling. J Cell Biochem (2013) 0.81
An atypical canonical bone morphogenetic protein (BMP) signaling pathway regulates Msh homeobox 1 (Msx1) expression during odontogenesis. J Biol Chem (2014) 0.81
Site-specific expression of gelatinolytic activity during morphogenesis of the secondary palate in the mouse embryo. PLoS One (2012) 0.81
Conditional deletion of the human ortholog gene Dicer1 in Pax2-Cre expression domain impairs orofacial development. Indian J Hum Genet (2012) 0.81
The skeletal site-specific role of connective tissue growth factor in prenatal osteogenesis. Dev Dyn (2012) 0.80
Roles of collagen and periostin expression by cranial neural crest cells during soft palate development. J Histochem Cytochem (2012) 0.80
Msx1 and Dlx5 function synergistically to regulate frontal bone development. Genesis (2010) 0.80
Localization of transforming growth factor beta receptor II interacting protein-1 in bone and teeth: implications in matrix mineralization. J Histochem Cytochem (2012) 0.80
Cranial sutures: a multidisciplinary review. Childs Nerv Syst (2013) 0.80
Cleft palate defect of Dlx1/2-/- mutant mice is caused by lack of vertical outgrowth in the posterior palate. Dev Dyn (2012) 0.80
Modulation of lipid metabolic defects rescues cleft palate in Tgfbr2 mutant mice. Hum Mol Genet (2013) 0.80
Type III transforming growth factor beta receptor regulates vascular and osteoblast development during palatogenesis. Dev Dyn (2014) 0.80
Transforming growth factor-β activates c-Myc to promote palatal growth. J Cell Biochem (2012) 0.79
Disruption of the ERK/MAPK pathway in neural crest cells as a potential cause of Pierre Robin sequence. Development (2015) 0.79
Chemokine-mediated migration of mesencephalic neural crest cells. Cytokine (2011) 0.79
Expression profiling of transforming growth factor beta superfamily genes in developing orofacial tissue. Birth Defects Res A Clin Mol Teratol (2006) 0.79
Molecular basis of cleft palates in mice. World J Biol Chem (2015) 0.78
Identification of Chiari Type I Malformation subtypes using whole genome expression profiles and cranial base morphometrics. BMC Med Genomics (2014) 0.78
Synovial joints: from development to homeostasis. Curr Osteoporos Rep (2015) 0.78
Cytomegalovirus induces abnormal chondrogenesis and osteogenesis during embryonic mandibular development. BMC Dev Biol (2008) 0.78
TGFβ superfamily signaling in the neural crest lineage. Cell Adh Migr (2011) 0.78
The expression of TGF-β3 for epithelial-mesenchyme transdifferentiated MEE in palatogenesis. J Mol Histol (2010) 0.77
Integration of comprehensive 3D microCT and signaling analysis reveals differential regulatory mechanisms of craniofacial bone development. Dev Biol (2015) 0.77
Single cell lineage tracing reveals a role for TgfβR2 in intestinal stem cell dynamics and differentiation. Proc Natl Acad Sci U S A (2016) 0.76
Human infection with a novel avian-origin influenza A (H7N9) virus. N Engl J Med (2013) 24.88
Stromal fibroblasts in cancer initiation and progression. Nature (2004) 11.69
TGF-beta signaling in fibroblasts modulates the oncogenic potential of adjacent epithelia. Science (2004) 10.23
Tumour microenvironment: TGFbeta: the molecular Jekyll and Hyde of cancer. Nat Rev Cancer (2006) 8.59
Abrogation of TGF beta signaling in mammary carcinomas recruits Gr-1+CD11b+ myeloid cells that promote metastasis. Cancer Cell (2008) 6.78
TGF-beta and cancer. Cytokine Growth Factor Rev (2005) 3.38
Biological features of novel avian influenza A (H7N9) virus. Nature (2013) 3.24
Conditional inactivation of the TGF-beta type II receptor using Cre:Lox. Genesis (2002) 3.21
Aggressive pancreatic ductal adenocarcinoma in mice caused by pancreas-specific blockade of transforming growth factor-beta signaling in cooperation with active Kras expression. Genes Dev (2006) 3.16
Adora2b-elicited Per2 stabilization promotes a HIF-dependent metabolic switch crucial for myocardial adaptation to ischemia. Nat Med (2012) 3.03
Tumor-stroma interactions. Curr Opin Genet Dev (2005) 2.89
Smad3 deficiency attenuates bleomycin-induced pulmonary fibrosis in mice. Am J Physiol Lung Cell Mol Physiol (2002) 2.83
Cross-interference of RLR and TLR signaling pathways modulates antibacterial T cell responses. Nat Immunol (2012) 2.72
Effect of conditional knockout of the type II TGF-beta receptor gene in mammary epithelia on mammary gland development and polyomavirus middle T antigen induced tumor formation and metastasis. Cancer Res (2005) 2.63
TGF-beta and immune cells: an important regulatory axis in the tumor microenvironment and progression. Trends Immunol (2010) 2.61
Activation of the Erk pathway is required for TGF-beta1-induced EMT in vitro. Neoplasia (2004) 2.60
A prospective, randomized study comparing outcomes and toxicities of intensity-modulated radiotherapy vs. conventional two-dimensional radiotherapy for the treatment of nasopharyngeal carcinoma. Radiother Oncol (2012) 2.54
Inhibiting Cxcr2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinoma. J Clin Invest (2011) 2.54
Inhibition of TGF-beta with neutralizing antibodies prevents radiation-induced acceleration of metastatic cancer progression. J Clin Invest (2007) 2.52
Loss of TGF-beta type II receptor in fibroblasts promotes mammary carcinoma growth and invasion through upregulation of TGF-alpha-, MSP- and HGF-mediated signaling networks. Oncogene (2005) 2.35
The roles of TGFβ in the tumour microenvironment. Nat Rev Cancer (2013) 2.35
Induction by transforming growth factor-beta1 of epithelial to mesenchymal transition is a rare event in vitro. Breast Cancer Res (2004) 2.33
A tale of two proteins: differential roles and regulation of Smad2 and Smad3 in TGF-beta signaling. J Cell Biochem (2007) 2.32
Role of SMAD and non-SMAD signals in the development of Th17 and regulatory T cells. J Immunol (2010) 2.20
The FaceBase Consortium: a comprehensive program to facilitate craniofacial research. Dev Biol (2011) 2.16
Transforming growth factor beta receptor type II inactivation induces the malignant transformation of intestinal neoplasms initiated by Apc mutation. Cancer Res (2006) 2.14
Multicentric peripheral ossifying fibroma. J Oral Sci (2006) 2.06
Increased malignancy of Neu-induced mammary tumors overexpressing active transforming growth factor beta1. Mol Cell Biol (2003) 1.99
Transforming growth factor beta (TGF-beta) and inflammation in cancer. Cytokine Growth Factor Rev (2009) 1.95
Oral bisphosphonate use and the prevalence of osteonecrosis of the jaw: an institutional inquiry. J Am Dent Assoc (2009) 1.84
Gr-1+CD11b+ myeloid cells tip the balance of immune protection to tumor promotion in the premetastatic lung. Cancer Res (2010) 1.83
Transcriptional cooperation between the transforming growth factor-beta and Wnt pathways in mammary and intestinal tumorigenesis. Cancer Res (2007) 1.81
Cell autonomous requirement for Tgfbr2 in the disappearance of medial edge epithelium during palatal fusion. Dev Biol (2006) 1.79
Antagonistic actions of Msx1 and Osr2 pattern mammalian teeth into a single row. Science (2009) 1.73
TGF-beta receptor deletion in the renal collecting system exacerbates fibrosis. J Am Soc Nephrol (2010) 1.70
Abrogation of TGF-beta signaling enhances chemokine production and correlates with prognosis in human breast cancer. J Clin Invest (2009) 1.68
Effect of antibiotic treatment on the intestinal metabolome. Antimicrob Agents Chemother (2011) 1.64
Transforming growth factor-beta regulates mammary carcinoma cell survival and interaction with the adjacent microenvironment. Cancer Res (2008) 1.64
A signaling pathway involving TGF-beta2 and snail in hair follicle morphogenesis. PLoS Biol (2004) 1.63
Formation and differentiation of multiple mesenchymal lineages during lung development is regulated by beta-catenin signaling. PLoS One (2008) 1.63
Transforming growth factor beta receptor type II inactivation promotes the establishment and progression of colon cancer. Cancer Res (2004) 1.62
Ectodermal Smad4 and p38 MAPK are functionally redundant in mediating TGF-beta/BMP signaling during tooth and palate development. Dev Cell (2008) 1.61
A haplotype map of genomic variations and genome-wide association studies of agronomic traits in foxtail millet (Setaria italica). Nat Genet (2013) 1.58
Effect of IGF-I in the chondrogenesis of bone marrow mesenchymal stem cells in the presence or absence of TGF-beta signaling. J Bone Miner Res (2006) 1.55
Combined deficiencies of Msx1 and Msx2 cause impaired patterning and survival of the cranial neural crest. Development (2005) 1.52
TGF-beta signaling is essential for joint morphogenesis. J Cell Biol (2007) 1.51
Epithelial and ectomesenchymal role of the type I TGF-beta receptor ALK5 during facial morphogenesis and palatal fusion. Dev Biol (2006) 1.50
Transgenic mice expressing a dominant-negative mutant type II transforming growth factor-beta receptor exhibit impaired mammary development and enhanced mammary tumor formation. Am J Pathol (2003) 1.46
Diagnosis of heart failure with preserved ejection fraction: which parameters and diagnostic strategies are more valuable? Eur J Heart Fail (2011) 1.46
Acute cardiovascular effects of the Wenchuan earthquake: ambulatory blood pressure monitoring of hypertensive patients. Hypertens Res (2009) 1.46
HIF1A reduces acute lung injury by optimizing carbohydrate metabolism in the alveolar epithelium. PLoS Biol (2013) 1.45
Bioactive nanofibers instruct cells to proliferate and differentiate during enamel regeneration. J Bone Miner Res (2008) 1.42
Cardiovascular malformations with normal smooth muscle differentiation in neural crest-specific type II TGFbeta receptor (Tgfbr2) mutant mice. Dev Biol (2005) 1.40
Tgfbeta signaling is required for atrioventricular cushion mesenchyme remodeling during in vivo cardiac development. Development (2006) 1.38
A delicate balance: TGF-beta and the tumor microenvironment. J Cell Biochem (2007) 1.38
Morphoregulation of teeth: modulating the number, size, shape and differentiation by tuning Bmp activity. Evol Dev (2005) 1.38
Modulation of noncanonical TGF-β signaling prevents cleft palate in Tgfbr2 mutant mice. J Clin Invest (2012) 1.37
The role of TGF-beta signaling in regulating chondrogenesis and osteogenesis during mandibular development. Dev Biol (2006) 1.36
Convergent genesis of an adult neural crest-like dermal stem cell from distinct developmental origins. Stem Cells (2010) 1.36
Role of Hertwig's epithelial root sheath cells in tooth root development. Dev Dyn (2003) 1.35
Proliferation of estrogen receptor-alpha-positive mammary epithelial cells is restrained by transforming growth factor-beta1 in adult mice. Am J Pathol (2005) 1.35
Hydrogen/deuterium exchange mass spectrometry with top-down electron capture dissociation for characterizing structural transitions of a 17 kDa protein. J Am Chem Soc (2009) 1.35
Modulation of BMP signaling by Noggin is required for the maintenance of palatal epithelial integrity during palatogenesis. Dev Biol (2010) 1.34
TGFbeta-mediated FGF signaling is crucial for regulating cranial neural crest cell proliferation during frontal bone development. Development (2006) 1.34
Transforming growth factor beta-regulated gene expression in a mouse mammary gland epithelial cell line. Breast Cancer Res (2003) 1.32
Identification of microbial biofilms in osteonecrosis of the jaws secondary to bisphosphonate therapy. J Oral Maxillofac Surg (2008) 1.32
Transforming growth factor beta: tumor suppressor or promoter? Are host immune cells the answer? Cancer Res (2008) 1.31
Fate of HERS during tooth root development. Dev Biol (2009) 1.31
Surveillance for Creutzfeldt-Jakob disease in China from 2006 to 2007. BMC Public Health (2008) 1.30
Microbial biofilms in osteomyelitis of the jaw and osteonecrosis of the jaw secondary to bisphosphonate therapy. J Am Dent Assoc (2009) 1.28
Enhanced hepatocyte growth factor signaling by type II transforming growth factor-beta receptor knockout fibroblasts promotes mammary tumorigenesis. Cancer Res (2007) 1.27
TGF-β receptor II loss promotes mammary carcinoma progression by Th17 dependent mechanisms. Cancer Discov (2011) 1.26
TGF-beta-induced RhoA and p160ROCK activation is involved in the inhibition of Cdc25A with resultant cell-cycle arrest. Proc Natl Acad Sci U S A (2003) 1.25