Published in Proc Natl Acad Sci U S A on August 21, 2007
A developmental and genetic classification for malformations of cortical development: update 2012. Brain (2012) 3.14
Retinoic acid from the meninges regulates cortical neuron generation. Cell (2009) 2.46
FOXC1 is required for normal cerebellar development and is a major contributor to chromosome 6p25.3 Dandy-Walker malformation. Nat Genet (2009) 1.66
Primary cellular meningeal defects cause neocortical dysplasia and dyslamination. Ann Neurol (2010) 1.48
What disorders of cortical development tell us about the cortex: one plus one does not always make two. Curr Opin Genet Dev (2011) 1.45
Growth and folding of the mammalian cerebral cortex: from molecules to malformations. Nat Rev Neurosci (2014) 1.44
We have got you 'covered': how the meninges control brain development. Curr Opin Genet Dev (2011) 1.14
Cerebellar development in the preterm neonate: effect of supratentorial brain injury. Pediatr Res (2009) 1.09
Polymicrogyria: pathology, fetal origins and mechanisms. Acta Neuropathol Commun (2014) 1.08
FOXC1 contributes to microvascular invasion in primary hepatocellular carcinoma via regulating epithelial-mesenchymal transition. Int J Biol Sci (2012) 1.07
Retinoic acid functions as a key GABAergic differentiation signal in the basal ganglia. PLoS Biol (2011) 1.06
Focusing forward genetics: a tripartite ENU screen for neurodevelopmental mutations in the mouse. Genetics (2011) 1.02
A cascade of morphogenic signaling initiated by the meninges controls corpus callosum formation. Neuron (2012) 0.96
Bmp7 regulates the survival, proliferation, and neurogenic properties of neural progenitor cells during corticogenesis in the mouse. PLoS One (2012) 0.94
FoxC1 is essential for vascular basement membrane integrity and hyaloid vessel morphogenesis. Invest Ophthalmol Vis Sci (2009) 0.94
Meningeal defects alter the tangential migration of cortical interneurons in Foxc1hith/hith mice. Neural Dev (2012) 0.93
Abnormal development of the human cerebral cortex. J Anat (2010) 0.92
Developmental disorders of the midbrain and hindbrain. Front Neuroanat (2012) 0.90
Impaired meningeal development in association with apical expansion of calvarial bone osteogenesis in the Foxc1 mutant. J Anat (2008) 0.90
Loss of Col3a1, the gene for Ehlers-Danlos syndrome type IV, results in neocortical dyslamination. PLoS One (2012) 0.88
Mutations in extracellular matrix genes NID1 and LAMC1 cause autosomal dominant Dandy-Walker malformation and occipital cephaloceles. Hum Mutat (2013) 0.88
Foxc1 is required by pericytes during fetal brain angiogenesis. Biol Open (2013) 0.87
Interaction between Foxc1 and Fgf8 during mammalian jaw patterning and in the pathogenesis of syngnathia. PLoS Genet (2013) 0.86
Foxc1 controls the growth of the murine frontal bone rudiment by direct regulation of a Bmp response threshold of Msx2. Development (2013) 0.85
Novel approaches to studying the genetic basis of cerebellar development. Cerebellum (2010) 0.84
Bone morphogenic protein signaling is a major determinant of dentate development. J Neurosci (2013) 0.82
New insights into behaviour using mouse ENU mutagenesis. Hum Mol Genet (2012) 0.80
Initiation of early osteoblast differentiation events through the direct transcriptional regulation of Msx2 by FOXC1. PLoS One (2012) 0.80
CoupTFI interacts with retinoic acid signaling during cortical development. PLoS One (2013) 0.79
Diverse Functions of Retinoic Acid in Brain Vascular Development. J Neurosci (2016) 0.78
A mouse model of early-onset renal failure due to a xanthine dehydrogenase nonsense mutation. PLoS One (2012) 0.78
A role for PDGF-C/PDGFRα signaling in the formation of the meningeal basement membranes surrounding the cerebral cortex. Biol Open (2016) 0.77
Midline craniofacial malformations with a lipomatous cephalocele are associated with insufficient closure of the neural tube in the tuft mouse. Birth Defects Res A Clin Mol Teratol (2014) 0.76
Cerebrovascular defects in Foxc1 mutants correlate with aberrant WNT and VEGF-A pathways downstream of retinoic acid from the meninges. Dev Biol (2016) 0.75
Col1a1+ perivascular cells in the brain are a source of retinoic acid following stroke. BMC Neurosci (2016) 0.75
Phenotypic outcomes in Mouse and Human Foxc1 dependent Dandy-Walker cerebellar malformation suggest shared mechanisms. Elife (2017) 0.75
Epithelial cells supply Sonic Hedgehog to the perinatal dentate gyrus via transport by platelets. Elife (2015) 0.75
Cell migration in the forebrain. Annu Rev Neurosci (2003) 4.59
Tissue origins and interactions in the mammalian skull vault. Dev Biol (2002) 3.95
Differential expression of multiple fork head related genes during gastrulation and axial pattern formation in the mouse embryo. Development (1993) 3.63
The forkhead transcription factor gene FKHL7 is responsible for glaucoma phenotypes which map to 6p25. Nat Genet (1998) 3.24
FAK deficiency in cells contributing to the basal lamina results in cortical abnormalities resembling congenital muscular dystrophies. Neuron (2003) 2.86
The cephalic neural crest provides pericytes and smooth muscle cells to all blood vessels of the face and forebrain. Development (2001) 2.78
Conditional inactivation of Tgfbr2 in cranial neural crest causes cleft palate and calvaria defects. Development (2003) 2.78
The forkhead/winged helix gene Mf1 is disrupted in the pleiotropic mouse mutation congenital hydrocephalus. Cell (1998) 2.41
Mutations of the forkhead/winged-helix gene, FKHL7, in patients with Axenfeld-Rieger anomaly. Am J Hum Genet (1998) 2.34
Haploinsufficiency of the transcription factors FOXC1 and FOXC2 results in aberrant ocular development. Hum Mol Genet (2000) 2.32
Murine forkhead/winged helix genes Foxc1 (Mf1) and Foxc2 (Mfh1) are required for the early organogenesis of the kidney and urinary tract. Development (2000) 2.23
The murine winged helix transcription factors, Foxc1 and Foxc2, are both required for cardiovascular development and somitogenesis. Genes Dev (2001) 2.15
The forkhead transcription factors, Foxc1 and Foxc2, are required for arterial specification and lymphatic sprouting during vascular development. Dev Biol (2006) 2.06
Beyond laminar fate: toward a molecular classification of cortical projection/pyramidal neurons. Dev Neurosci (2003) 2.02
A critical function of the pial basement membrane in cortical histogenesis. J Neurosci (2002) 2.00
A forkhead gene, FoxE3, is essential for lens epithelial proliferation and closure of the lens vesicle. Genes Dev (2000) 1.65
A focused and efficient genetic screening strategy in the mouse: identification of mutations that disrupt cortical development. PLoS Biol (2004) 1.64
A spectrum of FOXC1 mutations suggests gene dosage as a mechanism for developmental defects of the anterior chamber of the eye. Am J Hum Genet (2001) 1.50
Smooth, rough and upside-down neocortical development. Curr Opin Genet Dev (2002) 1.47
Analyses of the effects that disease-causing missense mutations have on the structure and function of the winged-helix protein FOXC1. Am J Hum Genet (2001) 1.32
A family with Axenfeld-Rieger syndrome and Peters Anomaly caused by a point mutation (Phe112Ser) in the FOXC1 gene. Am J Ophthalmol (2003) 1.30
Neovascularization and the appearance of morphological characteristics of the blood-brain barrier in the embryonic mouse central nervous system. Brain Res Dev Brain Res (1993) 1.24
The forkhead genes, Foxc1 and Foxc2, regulate paraxial versus intermediate mesoderm cell fate. Dev Biol (2004) 1.24
Progression of calvarial bone development requires Foxc1 regulation of Msx2 and Alx4. Dev Biol (2003) 1.23
Schizophrenia in an adult with 6p25 deletion syndrome. Am J Med Genet A (2006) 1.16
Meningeal cells organize the superficial glia limitans of the cerebellum and produce components of both the interstitial matrix and the basement membrane. J Neurocytol (1994) 1.15
The mechanism of drainage of the cerebrospinal fluid. Brain (1973) 1.15
Developmental morphology of the subarachnoid space and contiguous structures in the mouse. Am J Anat (1975) 1.14
Axenfeld-Rieger malformation and distinctive facial features: Clues to a recognizable 6p25 microdeletion syndrome. Am J Med Genet A (2005) 1.13
Subtelomeric 6p deletion: clinical, FISH, and array CGH characterization of two cases. Am J Med Genet A (2005) 1.12
Breaches of the pial basement membrane and disappearance of the glia limitans during development underlie the cortical lamination defect in the mouse model of muscle-eye-brain disease. J Comp Neurol (2007) 1.05
Foxc1 integrates Fgf and Bmp signalling independently of twist or noggin during calvarial bone development. Dev Dyn (2005) 0.97
Expression domains of murine ephrin-A5 in the pituitary and hypothalamus. Mech Dev (2000) 0.94
Regulation of FOXC1 stability and transcriptional activity by an epidermal growth factor-activated mitogen-activated protein kinase signaling cascade. J Biol Chem (2006) 0.88
Novel mutation in FOXC1 wing region causing Axenfeld-Rieger anomaly. Invest Ophthalmol Vis Sci (2002) 0.87
Sibs with Axenfeld-Rieger anomaly, hydrocephalus, and leptomeningeal calcifications: a new autosomal recessive syndrome? Am J Med Genet (1998) 0.82
Cortical dysplasia: neuropathological aspects. Childs Nerv Syst (2006) 0.79
Loss of the retrograde motor for IFT disrupts localization of Smo to cilia and prevents the expression of both activator and repressor functions of Gli. Dev Biol (2005) 3.63
Slit proteins prevent midline crossing and determine the dorsoventral position of major axonal pathways in the mammalian forebrain. Neuron (2002) 2.71
CXCR4 and CXCR7 have distinct functions in regulating interneuron migration. Neuron (2011) 2.69
The mammalian Cos2 homolog Kif7 plays an essential role in modulating Hh signal transduction during development. Curr Biol (2009) 2.63
Retinoic acid from the meninges regulates cortical neuron generation. Cell (2009) 2.46
A ciliopathy complex at the transition zone protects the cilia as a privileged membrane domain. Nat Cell Biol (2011) 2.43
The chemokine SDF1 regulates migration of dentate granule cells. Development (2002) 2.34
Aberrant seizure-induced neurogenesis in experimental temporal lobe epilepsy. Ann Neurol (2006) 2.22
Amelioration of type 2 diabetes by antibody-mediated activation of fibroblast growth factor receptor 1. Sci Transl Med (2011) 2.10
Stereotyped pruning of long hippocampal axon branches triggered by retraction inducers of the semaphorin family. Cell (2003) 1.92
Regional distribution of cortical interneurons and development of inhibitory tone are regulated by Cxcl12/Cxcr4 signaling. J Neurosci (2008) 1.67
A focused and efficient genetic screening strategy in the mouse: identification of mutations that disrupt cortical development. PLoS Biol (2004) 1.64
Wnt signaling mutants have decreased dentate granule cell production and radial glial scaffolding abnormalities. J Neurosci (2004) 1.60
Global defects in collagen secretion in a Mia3/TANGO1 knockout mouse. J Cell Biol (2011) 1.58
NMDA receptors inhibit synapse unsilencing during brain development. Proc Natl Acad Sci U S A (2008) 1.52
Wnt signaling in development and disease. Neurobiol Dis (2009) 1.51
Morphogenesis of the dentate gyrus: what we are learning from mouse mutants. Dev Neurosci (2005) 1.50
Primary cellular meningeal defects cause neocortical dysplasia and dyslamination. Ann Neurol (2010) 1.48
Isoflurane inhibits growth but does not cause cell death in hippocampal neural precursor cells grown in culture. Anesthesiology (2009) 1.46
Hippocampal and visuospatial learning defects in mice with a deletion of frizzled 9, a gene in the Williams syndrome deletion interval. Development (2005) 1.35
FGF19 regulates cell proliferation, glucose and bile acid metabolism via FGFR4-dependent and independent pathways. PLoS One (2011) 1.35
COUP-TFI coordinates cortical patterning, neurogenesis, and laminar fate and modulates MAPK/ERK, AKT, and beta-catenin signaling. Cereb Cortex (2007) 1.33
Kinome siRNA screen identifies regulators of ciliogenesis and hedgehog signal transduction. Sci Signal (2008) 1.33
Wnt signaling regulates neuronal differentiation of cortical intermediate progenitors. J Neurosci (2011) 1.31
Stromal-derived factor-1 (CXCL12) regulates laminar position of Cajal-Retzius cells in normal and dysplastic brains. J Neurosci (2006) 1.28
Rere controls retinoic acid signalling and somite bilateral symmetry. Nature (2010) 1.27
Regulation of prelamin A but not lamin C by miR-9, a brain-specific microRNA. Proc Natl Acad Sci U S A (2012) 1.26
Atrophin 2 recruits histone deacetylase and is required for the function of multiple signaling centers during mouse embryogenesis. Development (2003) 1.23
Chemical genetic identification of NDR1/2 kinase substrates AAK1 and Rabin8 Uncovers their roles in dendrite arborization and spine development. Neuron (2012) 1.22
Identification of a transient subpial neurogenic zone in the developing dentate gyrus and its regulation by Cxcl12 and reelin signaling. Development (2009) 1.19
We have got you 'covered': how the meninges control brain development. Curr Opin Genet Dev (2011) 1.14
The Rfx4 transcription factor modulates Shh signaling by regional control of ciliogenesis. Sci Signal (2009) 1.12
Functional characterization of putative cilia genes by high-content analysis. Mol Biol Cell (2011) 1.12
Severe defects in dorsal thalamic development in low-density lipoprotein receptor-related protein-6 mutants. J Neurosci (2004) 1.10
LRP2 in ependymal cells regulates BMP signaling in the adult neurogenic niche. J Cell Sci (2010) 1.10
A transgenic marker mouse line labels Cajal-Retzius cells from the cortical hem and thalamocortical axons. Brain Res (2006) 1.06
Ocular coloboma and dorsoventral neuroretinal patterning defects in Lrp6 mutant eyes. Dev Dyn (2008) 1.05
The ventral hippocampus is the embryonic origin for adult neural stem cells in the dentate gyrus. Neuron (2013) 1.04
Genetic regulation of dentate gyrus morphogenesis. Prog Brain Res (2007) 1.04
Conserved role of unc-79 in ethanol responses in lightweight mutant mice. PLoS Genet (2010) 1.00
Functional architecture of atrophins. J Biol Chem (2006) 1.00
Activation of protein kinase A induces neuronal differentiation of HiB5 hippocampal progenitor cells. Brain Res Mol Brain Res (2002) 0.99
Furin-cleaved proprotein convertase subtilisin/kexin type 9 (PCSK9) is active and modulates low density lipoprotein receptor and serum cholesterol levels. J Biol Chem (2012) 0.99
PACAP and its receptors exert pleiotropic effects in the nervous system by activating multiple signaling pathways. Curr Protein Pept Sci (2002) 0.98
Sox10 directs neural stem cells toward the oligodendrocyte lineage by decreasing Suppressor of Fused expression. Proc Natl Acad Sci U S A (2010) 0.98
Wnt signaling and forebrain development. Cold Spring Harb Perspect Biol (2012) 0.97
A cascade of morphogenic signaling initiated by the meninges controls corpus callosum formation. Neuron (2012) 0.96
A Titin mutation defines roles for circulation in endothelial morphogenesis. Dev Biol (2004) 0.96
Expression of SDF-1 and CXCR4 during reorganization of the postnatal dentate gyrus. Dev Neurosci (2007) 0.96
A tale of two signals: Wnt and Hedgehog in dentate neurogenesis. Sci STKE (2006) 0.96
Morphological defects in a novel Rdh10 mutant that has reduced retinoic acid biosynthesis and signaling. Genesis (2012) 0.95
Wnt signaling is regulated by endoplasmic reticulum retention. PLoS One (2009) 0.95
Embryonic and early postnatal abnormalities contributing to the development of hippocampal malformations in a rodent model of dysplasia. J Comp Neurol (2006) 0.94
Ethanol induces heterotopias in organotypic cultures of rat cerebral cortex. Cereb Cortex (2004) 0.94
Ongoing interplay between the neural network and neurogenesis in the adult hippocampus. Curr Opin Neurobiol (2010) 0.94
Meningeal defects alter the tangential migration of cortical interneurons in Foxc1hith/hith mice. Neural Dev (2012) 0.93
Wnts influence the timing and efficiency of oligodendrocyte precursor cell generation in the telencephalon. J Neurosci (2010) 0.93
Involvement of CLOCK:BMAL1 heterodimer in serum-responsive mPer1 induction. Neuroreport (2003) 0.93
Clock gene mouse period2 overexpression inhibits growth of human pancreatic cancer cells and has synergistic effect with cisplatin. Anticancer Res (2009) 0.93
A mutation in the pericentrin gene causes abnormal interneuron migration to the olfactory bulb in mice. Dev Biol (2010) 0.90
Chondroitin sulfate synthase 1 (Chsy1) is required for bone development and digit patterning. Dev Biol (2012) 0.89
Foxc1 is required by pericytes during fetal brain angiogenesis. Biol Open (2013) 0.87
Hilar mossy cells share developmental influences with dentate granule neurons. Dev Neurosci (2007) 0.87
Excision of the first intron from the gonadotropin-releasing hormone (GnRH) transcript serves as a key regulatory step for GnRH biosynthesis. J Biol Chem (2003) 0.87
ATP-binding cassette transporter ABCA2 (ABC2) expression in the developing spinal cord and PNS during myelination. J Comp Neurol (2002) 0.86
Genetic control of hippocampal neurogenesis. Genome Biol (2006) 0.84
Wnt signaling regulates intermediate precursor production in the postnatal dentate gyrus by regulating CXCR4 expression. Dev Neurosci (2012) 0.83
Calcium-independent inhibition of PCSK9 by affinity-improved variants of the LDL receptor EGF(A) domain. J Mol Biol (2012) 0.83
The development of hippocampal cellular assemblies. Wiley Interdiscip Rev Dev Biol (2013) 0.82
Bone morphogenic protein signaling is a major determinant of dentate development. J Neurosci (2013) 0.82
Inducible genetic lineage tracing of cortical hem derived Cajal-Retzius cells reveals novel properties. PLoS One (2011) 0.82
Wnt5a controls neurite development in olfactory bulb interneurons. ASN Neuro (2011) 0.82
Frizzled-9 promoter drives expression of transgenes in the medial wall of the cortex and its chief derivative the hippocampus. Genesis (2004) 0.82
Expression of the BMP antagonist Dan during murine forebrain development. Brain Res Dev Brain Res (2003) 0.82
Cxcl12/Cxcr4 signaling controls the migration and process orientation of A9-A10 dopaminergic neurons. Development (2013) 0.81
Frizzled9 protein is regionally expressed in the developing medial cortical wall and the cells derived from this region. Brain Res Dev Brain Res (2005) 0.81
Dual origins of the mammalian accessory olfactory bulb revealed by an evolutionarily conserved migratory stream. Nat Neurosci (2013) 0.80
Oligogenesis and oligodendrocyte progenitor maturation vary in different brain regions and partially correlate with local angiogenesis after ischemic stroke. Transl Stroke Res (2011) 0.80