Published in J Biol Chem on March 15, 1992
Phosphoinositides: tiny lipids with giant impact on cell regulation. Physiol Rev (2013) 3.21
Green fluorescent protein (GFP)-tagged cysteine-rich domains from protein kinase C as fluorescent indicators for diacylglycerol signaling in living cells. J Cell Biol (1998) 2.65
Synthesis and function of membrane phosphoinositides in budding yeast, Saccharomyces cerevisiae. Biochim Biophys Acta (2007) 2.08
Phosphoinositide signaling pathways in nuclei are associated with nuclear speckles containing pre-mRNA processing factors. Mol Biol Cell (1998) 2.07
Cellular mechanisms underlying acquired epilepsy: the calcium hypothesis of the induction and maintainance of epilepsy. Pharmacol Ther (2004) 1.94
Association of phosphatidylinositol 3-kinase with nuclear transcription sites in higher plants. Plant Cell (2000) 1.81
Structure, subnuclear distribution, and nuclear matrix association of the mammalian telomeric complex. J Cell Biol (1996) 1.75
Nuclear Translocation of fibroblast growth factor (FGF) receptors in response to FGF-2. J Cell Biol (1996) 1.72
Phosphatidylinositol 3- and 4-phosphate are required for normal stomatal movements. Plant Cell (2002) 1.48
PIK1, an essential phosphatidylinositol 4-kinase associated with the yeast nucleus. EMBO J (1994) 1.45
Inositol lipids are regulated during cell cycle progression in the nuclei of murine erythroleukaemia cells. Biochem J (2001) 1.41
Phosphoinositide signaling: new tools and insights. Physiology (Bethesda) (2009) 1.41
Nuclear phosphoinositides: a signaling enigma wrapped in a compartmental conundrum. Trends Cell Biol (2009) 1.37
PIP5K9, an Arabidopsis phosphatidylinositol monophosphate kinase, interacts with a cytosolic invertase to negatively regulate sugar-mediated root growth. Plant Cell (2007) 1.34
A mutation in PLC1, a candidate phosphoinositide-specific phospholipase C gene from Saccharomyces cerevisiae, causes aberrant mitotic chromosome segregation. Mol Cell Biol (1993) 1.27
Phosphoinositide signalling enzymes in rat liver nuclei: phosphoinositidase C isoform beta 1 is specifically, but not predominantly, located in the nucleus. Biochem J (1993) 1.21
Source of nuclear calcium signals. Proc Natl Acad Sci U S A (1994) 1.17
Metabolism and possible compartmentalization of inositol lipids in isolated rat-liver nuclei. Biochem J (1997) 1.16
A 104-kDa diacylglycerol kinase containing ankyrin-like repeats localizes in the cell nucleus. Proc Natl Acad Sci U S A (1996) 1.09
An electrostatic switch displaces phosphatidylinositol phosphate kinases from the membrane during phagocytosis. J Cell Biol (2009) 1.08
A protein that is highly related to GTPase-activating protein-associated p62 complexes with phospholipase C gamma. Mol Cell Biol (1994) 1.05
Identification of nuclear phosphatidylinositol 4,5-bisphosphate-interacting proteins by neomycin extraction. Mol Cell Proteomics (2010) 0.99
Nuclear diacylglycerol is increased during cell proliferation in vivo. Biochem J (1993) 0.96
Nucleus-associated phosphorylation of Ins(1,4,5)P3 to InsP6 in Dictyostelium. Biochem J (1995) 0.92
Monoclonal antibodies to phosphatidylinositol 4-phosphate 5-kinase: distribution and intracellular localization of the C isoform. Biochem J (1993) 0.85
A role for phosphoinositides in regulating plant nuclear functions. Front Plant Sci (2012) 0.85
Cytoplasmic and nuclear phospholipase C-beta 1 relocation: role in resumption of meiosis in the mouse oocyte. Mol Biol Cell (2000) 0.82
Nuclear matrix proteome analysis of Drosophila melanogaster. Mol Cell Proteomics (2010) 0.82
Changes in the components of a nuclear inositide cycle during differentiation in murine erythroleukaemia cells. Biochem J (1995) 0.81
The novel poly(A) polymerase Star-PAP is a signal-regulated switch at the 3'-end of mRNAs. Adv Biol Regul (2012) 0.80
Phospholipase C is involved in kinetochore function in Saccharomyces cerevisiae. Mol Cell Biol (2000) 0.80
Genetic evidence for a role of phospholipase C at the budding yeast kinetochore. Mol Genet Genomics (2003) 0.79
Changes in the nuclear matrix of chicken erythrocytes that accompany maturation. Biochem J (1996) 0.79
Confocal fluorescence microscopy for studying thapsigargin-induced bivalent-cation entry into B cells. Biochem J (1995) 0.77
The asymmetric distribution of phospholipids in the human red cell membrane. A combined study using phospholipases and freeze-etch electron microscopy. Biochim Biophys Acta (1973) 3.83
Lipidic intramembranous particles. Biochim Biophys Acta (1984) 2.39
The cell wall architecture of Candida albicans wild-type cells and cell wall-defective mutants. Mol Microbiol (2000) 2.27
The EGF receptor is an actin-binding protein. J Cell Biol (1992) 1.86
Influence of Ca2+ and Mg2+ on the thermotropic behaviour and permeability properties of liposomes prepared from dimyristoyl phosphatidylglycerol and mixtures of dimyristoyl phosphatidylglycerol and dimyristoyl phosphatidylcholine. Biochim Biophys Acta (1975) 1.85
Comparative studies on the effects of pH and Ca2+ on bilayers of various negatively charged phospholipids and their mixtures with phosphatidylcholine. Biochim Biophys Acta (1978) 1.83
Phase transitions of phospholipid bilayers and membranes of Acholeplasma laidlawii B visualized by freeze fracturing electron microscopy. Biochim Biophys Acta (1972) 1.81
Phosphoinositide kinase, diacylglycerol kinase, and phospholipase C activities associated to the cytoskeleton: effect of epidermal growth factor. J Cell Biol (1991) 1.75
Freeze-etch electron microscopy of erythrocytes, Acholeplasma laidlawii cells and liposomal membranes after the action of filipin and amphotericin B. Biochim Biophys Acta (1973) 1.68
Signal transduction by epidermal growth factor occurs through the subclass of high affinity receptors. J Cell Biol (1989) 1.68
Identification of connexin43 as a functional target for Wnt signalling. J Cell Sci (1998) 1.64
Modular closed-loop control of diabetes. IEEE Trans Biomed Eng (2012) 1.61
Influence of aldehyde fixation on the morphology of endosomes and lysosomes: quantitative analysis and electron tomography. J Microsc (2003) 1.59
Association and colocalization of Eps15 with adaptor protein-2 and clathrin. J Cell Biol (1997) 1.57
Integrin-dependent translocation of phosphoinositide 3-kinase to the cytoskeleton of thrombin-activated platelets involves specific interactions of p85 alpha with actin filaments and focal adhesion kinase. J Cell Biol (1995) 1.57
The influence of dolichol, dolichol esters, and dolichyl phosphate on phospholipid polymorphism and fluidity in model membranes. J Biol Chem (1985) 1.52
Sodium/proton exchange in mouse neuroblastoma cells. J Biol Chem (1981) 1.51
Ionic responses and growth stimulation induced by nerve growth factor and epidermal growth factor in rat pheochromocytoma (PC12) cells. J Cell Biol (1983) 1.51
Production of monoclonal antibodies against swine fever virus and their use in laboratory diagnosis. Vet Microbiol (1986) 1.50
Endosomal compartmentalization in three dimensions: implications for membrane fusion. Proc Natl Acad Sci U S A (2003) 1.47
Three classes of epidermal growth factor receptors on HeLa cells. J Biol Chem (1991) 1.43
Epidermal growth factor receptors associated to cytoskeletal elements of epidermoid carcinoma (A431) cells. J Cell Biol (1986) 1.43
Calorimetric and freeze-etch study of the influence of Mg2+ on the thermotropic behaviour of phosphatidylglycerol. Chem Phys Lipids (1975) 1.40
Lipidic intramembranous particles. Nature (1979) 1.39
Involvement of microbodies in penicillin biosynthesis. Biochim Biophys Acta (1992) 1.38
Interaction of pp60c-src, phospholipase C, inositol-lipid, and diacyglycerol kinases with the cytoskeletons of thrombin-stimulated platelets. J Biol Chem (1991) 1.37
Function of trehalose and glycogen in cell cycle progression and cell viability in Saccharomyces cerevisiae. J Bacteriol (1999) 1.32
Anaerobic transport in Escherichia coli membrane vesicles. J Biol Chem (1975) 1.32
The influence of pH, Ca2+ and protein on the thermotropic behaviour of the negatively charged phospholipid, phosphatidylglycerol. Biochim Biophys Acta (1974) 1.32
Focused ion beam-scanning electron microscope: exploring large volumes of atherosclerotic tissue. J Microsc (2009) 1.30
Visualization of epidermal growth factor receptor in cryosections of cultured A431 cells by immuno-gold labeling. Eur J Cell Biol (1985) 1.30
Protein kinase Czeta is a negative regulator of protein kinase B activity. J Biol Chem (1999) 1.29
Membrane fusion and the lamellar-to-inverted-hexagonal phase transition in cardiolipin vesicle systems induced by divalent cations. Biophys J (1999) 1.26
Localization of the pathway of the penicillin biosynthesis in Penicillium chrysogenum. EMBO J (1991) 1.26
Effects of different carbon fluxes on G1 phase duration, cyclin expression, and reserve carbohydrate metabolism in Saccharomyces cerevisiae. J Bacteriol (1997) 1.26
Immunoaffinity purification and characterization of the envelope protein E1 of hog cholera virus. J Gen Virol (1990) 1.23
Direct visualization and quantitative analysis of epidermal growth factor-induced receptor clustering. J Cell Physiol (1988) 1.21
Effect of glycophorin incorporation on the physico-chemical properties of phospholipid bilayers. Biochim Biophys Acta (1978) 1.20
Fragility of the permeability barrier of Escherichia coli. Biochim Biophys Acta (1972) 1.19
Epidermal growth factor induces ubiquitination of Eps15. J Biol Chem (1997) 1.19
Analysis of the crystallization process in lecithin liposomes: a freeze-etch study. Biochim Biophys Acta (1973) 1.19
The effect of lipid phase transitions on the architecture of bacterial membranes. Biochim Biophys Acta (1974) 1.18
Epidermal growth factor induces rapid and transient association of phospholipase C-gamma 1 with EGF-receptor and filamentous actin at membrane ruffles of A431 cells. J Cell Sci (1995) 1.17
The epidermal growth factor receptor is associated with actin filaments. Exp Cell Res (1992) 1.16
Cell fate determination during G1 phase progression. Cell Mol Life Sci (2007) 1.15
Fusion of phospholipid vesicles in association with the appearance of lipidic particles as visualized by freeze fracturing. Biochim Biophys Acta (1979) 1.14
Analysis of the hexagonal II phase and its relations to lipidic particles and the lamellar phase. A freeze-fracture study. Biochim Biophys Acta (1981) 1.14
Epidermal growth factor induces rapid reorganization of the actin microfilament system in human A431 cells. J Cell Sci (1991) 1.12
The interaction of spectrin - actin and synthetic phospholipids. Biochim Biophys Acta (1977) 1.09
Localization of synthesis of beta1,6-glucan in Saccharomyces cerevisiae. J Bacteriol (1999) 1.09
The lipidic particle as an intermediate structure in membrane fusion processes and bilayer to hexagonal HII transitions. Biochim Biophys Acta (1980) 1.07
Freeze etch morphology of outer membrane mutants of Escherichia coli K12. Biochim Biophys Acta (1976) 1.07
Stigmasterol: a phytosterol with potential anti-osteoarthritic properties. Osteoarthritis Cartilage (2009) 1.06
Relationship between phosphoinositide kinase activities and protein tyrosine phosphorylation in plasma membranes from A431 cells. Biochem J (1990) 1.06
Involvement of platelet glycoprotein IIb-IIIa (alpha IIb-beta 3 integrin) in thrombin-induced synthesis of phosphatidylinositol 3',4'-bisphosphate. J Biol Chem (1991) 1.06
Polymorphic phase behaviour of cardiolipin from bovine heart and from Bacillus subtilis as detected by 31P-NMR and freeze-fracture techniques. Effects of Ca2+, Mg2+, Ba2+ and temperature. Biochim Biophys Acta (1982) 1.06
Divalent cations and chlorpromazine can induce non-bilayer structures in phosphatidic acid-containing model membranes. Biochim Biophys Acta (1982) 1.06
Automated high-throughput electron tomography by pre-calibration of image shifts. J Microsc (2002) 1.05
Freeze-fracture morphology of biological membranes. Biochim Biophys Acta (1978) 1.05
Introduction of an N-glycosylation site increases secretion of heterologous proteins in yeasts. Appl Environ Microbiol (2000) 1.05
Phospholipid asymmetry in cardiac sarcolemma. Analysis of intact cells and 'gas-dissected' membranes. Biochim Biophys Acta (1988) 1.05
Induction of non-bilayer lipid structures by functional signal peptides. EMBO J (1990) 1.05
Antibody-induced dimerization activates the epidermal growth factor receptor tyrosine kinase. J Biol Chem (1991) 1.04
Bicarbonate stimulated phospholipid scrambling induces cholesterol redistribution and enables cholesterol depletion in the sperm plasma membrane. J Cell Sci (2001) 1.04
Active transport by membrane vesicles from anaerobically grown Escherichia coli energized by electron transfer to ferricyanide and chlorate. Eur J Biochem (1976) 1.04
Tomography of insulating biological and geological materials using focused ion beam (FIB) sectioning and low-kV BSE imaging. J Microsc (2009) 1.02
Nerve growth factor-induced changes in the intracellular localization of the protein kinase C substrate B-50 in pheochromocytoma PC12 cells. J Cell Biol (1989) 1.02
Freeze-substitution and Lowicryl HM20 embedding of fixed rat brain: suitability for immunogold ultrastructural localization of neural antigens. J Histochem Cytochem (1991) 1.01
Ligand-induced association of epidermal growth factor receptor to the cytoskeleton of A431 cells. J Cell Biochem (1989) 1.01
Cation transport and growth regulation in neuroblastoma cells. Modulations of K+ transport and electrical membrane properties during the cell cycle. J Cell Physiol (1981) 1.01
The distribution of cholesterol in bilayers of phosphatidylcholines as visualized by freeze fracturing. Biochim Biophys Acta (1974) 1.01
Energy supply for active transport in anaerobically grown Escherichia coli. J Bacteriol (1978) 1.01
A431 cell variants lacking the blood group A antigen display increased high affinity epidermal growth factor-receptor number, protein-tyrosine kinase activity, and receptor turnover. J Cell Biol (1988) 1.01
Amino acid transport in membrane vesicles of obligately anaerobic Veillonella alcalescens. J Bacteriol (1975) 1.00
Penetration of the signal sequence of Escherichia coli PhoE protein into phospholipid model membranes leads to lipid-specific changes in signal peptide structure and alterations of lipid organization. Biochemistry (1988) 1.00
Impaired cutinase secretion in Saccharomyces cerevisiae induces irregular endoplasmic reticulum (ER) membrane proliferation, oxidative stress, and ER-associated degradation. Appl Environ Microbiol (2002) 1.00
The novel inositol lipid phosphatidylinositol 3,4-bisphosphate is produced by human blood platelets upon thrombin stimulation. Biochem J (1990) 1.00
Gridded Aclar: preparation methods and use for correlative light and electron microscopy of cell monolayers, by TEM and FIB-SEM. J Microsc (2010) 1.00
Surfactant protein A is localized at the corners of the pulmonary tubular myelin lattice. J Histochem Cytochem (1991) 1.00
Extracellular matrix formation after transplantation of human embryonic stem cell-derived cardiomyocytes. Cell Mol Life Sci (2009) 1.00
Penetration of a cardiotoxin into cardiolipin model membranes and its implications on lipid organization. Biochemistry (1985) 0.99
Interaction of epidermal growth factor receptors with the cytoskeleton is related to receptor clustering. J Cell Physiol (1990) 0.99
Steric hindrance in immunolabelling. J Microsc (1986) 0.99
Respiratory chain linked ferricy anide reduction drives active transport in membrane vesicles from Bacillus subtilis. FEBS Lett (1975) 0.99
Epidermal growth factor receptor expression during morphological differentiation of pheochromocytoma cells, induced by nerve growth factor or dibutyryl cyclic AMP. J Cell Physiol (1987) 0.98
Impaired secretion of a hydrophobic cutinase by Saccharomyces cerevisiae correlates with an increased association with immunoglobulin heavy-chain binding protein (BiP). Appl Environ Microbiol (1998) 0.98
Glucose repression in Saccharomyces cerevisiae is related to the glucose concentration rather than the glucose flux. J Biol Chem (1998) 0.98