Published in Ciba Found Symp on January 01, 1992
GATA factors are essential for activity of the neuron-specific enhancer of the gonadotropin-releasing hormone gene. Mol Cell Biol (1996) 1.15
Interleukin-10 regulated gene expression in cells of hypothalamic-pituitary-adrenal axis origin. Cell Mol Neurobiol (2007) 0.81
Neurokinin B causes acute GnRH secretion and repression of GnRH transcription in GT1-7 GnRH neurons. Mol Endocrinol (2013) 0.79
Administration of connexin43 siRNA abolishes secretory pulse synchronization in GnRH clonal cell populations. Mol Cell Endocrinol (2009) 0.78
Cytokine regulation of tryptophan metabolism in the hypothalamic-pituitary-adrenal (HPA) axis: implications for protective and toxic consequences in neuroendocrine regulation. Cell Mol Neurobiol (2005) 0.76
Neurokinin B induces c-fos transcription via protein kinase C and activation of serum response factor and Elk-1 in immortalized GnRH neurons. Endocrinology (2014) 0.76
The protein kinase complement of the human genome. Science (2002) 35.36
Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity. Science (1999) 4.70
Immortalization of hypothalamic GnRH neurons by genetically targeted tumorigenesis. Neuron (1990) 4.15
Establishment of an osteocyte-like cell line, MLO-Y4. J Bone Miner Res (1997) 2.55
Structure of cloned DNA complementary to rat prolactin messenger RNA. J Biol Chem (1980) 2.44
A hypothalamic neuronal cell line persistently infected with scrapie prions exhibits apoptosis. J Virol (1997) 2.32
Cell lines of the pituitary gonadotrope lineage derived by targeted oncogenesis in transgenic mice. Mol Endocrinol (1990) 2.05
Ras protein farnesyltransferase: A strategic target for anticancer therapeutic development. J Clin Oncol (1999) 2.00
Mice lacking the norepinephrine transporter are supersensitive to psychostimulants. Nat Neurosci (2000) 1.93
Apoptosis or retinoblastoma: alternative fates of photoreceptors expressing the HPV-16 E7 gene in the presence or absence of p53. Genes Dev (1994) 1.91
Immortalization of pituitary cells at discrete stages of development by directed oncogenesis in transgenic mice. Development (1996) 1.87
Preputial separation as an external sign of pubertal development in the male rat. Biol Reprod (1977) 1.72
Tissue and cellular distribution of the extended family of protein kinase C isoenzymes. J Cell Biol (1992) 1.69
Increased synthesis of glutathione S-transferases in response to anticarcinogenic antioxidants. Cloning and measurement of messenger RNA. J Biol Chem (1983) 1.68
Generation and synchronization of gonadotropin-releasing hormone (GnRH) pulses: intrinsic properties of the GT1-1 GnRH neuronal cell line. Proc Natl Acad Sci U S A (1992) 1.62
cAMP-dependent protein kinase inhibits the mitogenic action of vascular endothelial growth factor and fibroblast growth factor in capillary endothelial cells by blocking Raf activation. J Cell Biochem (1997) 1.61
Reciprocal regulation of neu tyrosine kinase activity and caveolin-1 protein expression in vitro and in vivo. Implications for human breast cancer. J Biol Chem (1998) 1.61
Cerebellar defects in Ca2+/calmodulin kinase IV-deficient mice. J Neurosci (2000) 1.55
Anovulation in cyclooxygenase-2-deficient mice is restored by prostaglandin E2 and interleukin-1beta. Endocrinology (1999) 1.51
The 16-kilodalton N-terminal fragment of human prolactin is a potent inhibitor of angiogenesis. Endocrinology (1993) 1.50
Intrinsic pulsatile secretory activity of immortalized luteinizing hormone-releasing hormone-secreting neurons. Proc Natl Acad Sci U S A (1992) 1.46
Specific caspase interactions and amplification are involved in selective neuronal vulnerability in Huntington's disease. Cell Death Differ (2004) 1.44
Autophagy promotes T-cell survival through degradation of proteins of the cell death machinery. Cell Death Differ (2011) 1.42
Role of brain monoamines and histamine in regulation of anterior pituitary secretion. Physiol Rev (1978) 1.37
Half helical turn spacing changes convert a frog into a mouse rDNA promoter: a distant upstream domain determines the helix face of the initiation site. Genes Dev (1990) 1.36
Opposing actions of intact and N-terminal fragments of the human prolactin/growth hormone family members on angiogenesis: an efficient mechanism for the regulation of angiogenesis. Proc Natl Acad Sci U S A (1999) 1.35
Activation of mitogen-activated protein kinases by vascular endothelial growth factor and basic fibroblast growth factor in capillary endothelial cells is inhibited by the antiangiogenic factor 16-kDa N-terminal fragment of prolactin. Proc Natl Acad Sci U S A (1995) 1.35
Immortalized murine osteoblasts derived from BMP 2-T-antigen expressing transgenic mice. Endocrinology (1996) 1.32
Characterization of the mouse tartrate-resistant acid phosphatase (TRAP) gene promoter. J Bone Miner Res (1995) 1.32
Vulval schistosomiasis. J R Soc Med (1993) 1.30
Targeted disruption of the mouse gene encoding steroidogenic acute regulatory protein provides insights into congenital lipoid adrenal hyperplasia. Proc Natl Acad Sci U S A (1997) 1.30
Effects of castration and chronic steroid treatments on hypothalamic gonadotropin-releasing hormone content and pituitary gonadotropins in male wild-type and estrogen receptor-alpha knockout mice. Endocrinology (1998) 1.27
Induction of vascular endothelial growth factor and hypoxia-inducible factor-1alpha by global ischemia in rat brain. Neuroscience (2000) 1.26
Release of prostaglandin Es by hypothalamic tissue: evidence for their involvement in catecholamine-induced luteinizing hormone-releasing hormone release. Endocrinology (1979) 1.25
Selective regulation of expression of protein kinase C (PKC) isoenzymes in multidrug-resistant MCF-7 cells. Functional significance of enhanced expression of PKC alpha. J Biol Chem (1993) 1.23
Anterior pituitary hypoplasia and dwarfism in mice lacking the dopamine transporter. Neuron (1997) 1.21
Two distant and precisely positioned domains promote transcription of Xenopus laevis rRNA genes: analysis with linker-scanning mutants. Mol Cell Biol (1986) 1.18
Morphological characterization of immortalized hypothalamic neurons synthesizing luteinizing hormone-releasing hormone. Endocrinology (1991) 1.18
Metabolism of pro-luteinizing hormone-releasing hormone in immortalized hypothalamic neurons. Endocrinology (1991) 1.17
Increased tumor proliferation and genomic instability without decreased apoptosis in MMTV-ras mice deficient in p53. Mol Cell Biol (1997) 1.17
Mice lacking synapsin III show abnormalities in explicit memory and conditioned fear. Genes Brain Behav (2009) 1.17
Catecholaminergic modulation of luteinizing hormone-releasing hormone release by median eminence terminals in vitro. Endocrinology (1979) 1.16
The Xenopus ribosomal DNA 60- and 81-base-pair repeats are position-dependent enhancers that function at the establishment of the preinitiation complex: analysis in vivo and in an enhancer-responsive in vitro system. Mol Cell Biol (1989) 1.15
GATA factors are essential for activity of the neuron-specific enhancer of the gonadotropin-releasing hormone gene. Mol Cell Biol (1996) 1.15
A farnesyltransferase inhibitor induces tumor regression in transgenic mice harboring multiple oncogenic mutations by mediating alterations in both cell cycle control and apoptosis. Mol Cell Biol (1998) 1.14
Genetic determinants of response to chemotherapy in transgenic mouse mammary and salivary tumors. Oncogene (2000) 1.14
Organic anion and cation transporter expression and function during embryonic kidney development and in organ culture models. Kidney Int (2006) 1.13
Responses in the brain of estrogen receptor alpha-disrupted mice. Proc Natl Acad Sci U S A (1997) 1.13
A neuron-specific enhancer targets expression of the gonadotropin-releasing hormone gene to hypothalamic neurosecretory neurons. Mol Endocrinol (1995) 1.13
Induction of vascular endothelial growth factor receptors and phosphatidylinositol 3'-kinase/Akt signaling by global cerebral ischemia in the rat. Neuroscience (2000) 1.12
Employing a transgenic animal model to obtain cementoblasts in vitro. J Periodontol (2000) 1.12
Calcium and proton transport in membrane vesicles from barley roots. Plant Physiol (1990) 1.10
Spatial memory is related to hippocampal subcellular concentrations of calcium-dependent protein kinase C isoforms in young and aged rats. Proc Natl Acad Sci U S A (1997) 1.09
Novel hypothalamic arachidonate products stimulate somatostatin release from the median eminence. Endocrinology (1983) 1.09
Animals lacking endothelin-converting enzyme-2 are deficient in learning and memory. Genes Brain Behav (2008) 1.09
Nitric oxide regulates luteinizing hormone-releasing hormone secretion. Endocrinology (1993) 1.08
Lateral femoral cutaneous neuralgia: an anatomical insight. Clin Anat (2003) 1.07
Hypothalamic astrocytes respond to transforming growth factor-alpha with the secretion of neuroactive substances that stimulate the release of luteinizing hormone-releasing hormone. Endocrinology (1997) 1.06
Intracellular responses to gonadotropin-releasing hormone in a clonal cell line of the gonadotrope lineage. Mol Endocrinol (1991) 1.06
Anatomy and physiology of central galanin-containing pathways. Prog Neurobiol (1993) 1.05
Selective regulation of protein kinase C isoenzymes by oleic acid in human platelets. J Biol Chem (1993) 1.05
Expression of a retinoblastoma transgene results in dwarf mice. Genes Dev (1993) 1.05
Postdural puncture headache is a risk factor for new postdural puncture headache. Cephalalgia (2007) 1.03
CB1 cannabinoid receptor induction in experimental stroke. Ann Neurol (2000) 1.03
Impact of the environment on reproductive health: executive summary. Environ Health Perspect (1993) 0.99
Immortalization of osteoclast precursors by targeting Bcl -XL and Simian virus 40 large T antigen to the osteoclast lineage in transgenic mice. J Clin Invest (1998) 0.99
Direct arterial vascularization of estrogen-induced prolactin-secreting anterior pituitary tumors. Proc Natl Acad Sci U S A (1984) 0.98
Angiotensin II-like immunoreactivity in human ovarian follicular fluid. J Clin Endocrinol Metab (1986) 0.97
A specific, high affinity, saturable binding site for the 16-kilodalton fragment of prolactin on capillary endothelial cells. Endocrinology (1992) 0.97
Aromatization and 5alpha-reduction of androgens in discrete hypothalamic and limbic regions of the male and female rat. Endocrinology (1977) 0.96
A selective retinoid X receptor agonist bexarotene (LGD1069, targretin) inhibits angiogenesis and metastasis in solid tumours. Br J Cancer (2006) 0.95
Differential psychostimulant-induced activation of neural circuits in dopamine transporter knockout and wild type mice. Neuroscience (2003) 0.95
Regulation of gonadotropin-releasing hormone by protein kinase-A and -C in immortalized hypothalamic neurons. Endocrinology (1993) 0.95
Novel, non-steroidal, selective androgen receptor modulators (SARMs) with anabolic activity in bone and muscle and improved safety profile. J Musculoskelet Neuronal Interact (2002) 0.94
A decline in myometrial nitric oxide synthase expression is associated with labor and delivery. J Clin Invest (1997) 0.94
Inhibition of urokinase activity by the antiangiogenic factor 16K prolactin: activation of plasminogen activator inhibitor 1 expression. Endocrinology (1998) 0.94
Altered expression of the neuropeptide-processing enzyme carboxypeptidase E in the rat brain after global ischemia. J Cereb Blood Flow Metab (2001) 0.94
Role of the cAMP signaling pathway in the regulation of gonadotropin-releasing hormone secretion in GT1 cells. Proc Natl Acad Sci U S A (2000) 0.94
Evidence for a negative ultrashort loop feedback mechanism operating on the luteinizing hormone-releasing hormone neuronal system. Endocrinology (1987) 0.94
A transgenic mouse model for trilateral retinoblastoma. Arch Ophthalmol (1990) 0.94
Combined retrograde tracing and immunocytochemical identification of luteinizing hormone-releasing hormone- and somatostatin-containing neurons projecting to the median eminence of the rat. Endocrinology (1989) 0.93
Defective phorbol ester-stimulated secretion of beta-amyloid precursor protein from Alzheimer's disease fibroblasts. Neurosci Lett (1995) 0.93
Gonadotropin-releasing hormone neuronal cell lines. Front Neuroendocrinol (1992) 0.93
Fixation, fine structure, and immunostaining for neuropeptides: perfusion versus immersion of the neuroendocrine hypothalamus. J Histochem Cytochem (1986) 0.93
Retinoblastoma in transgenic mice: models of hereditary retinoblastoma. Surv Ophthalmol (1999) 0.93
Role of oxytocin on prolactin secretion during proestrus and in different physiological or pharmacological paradigms. Endocrinology (1988) 0.92
Infundibular gonadotropin-releasing hormone neurons are inhibited by direct opioid and autoregulatory synapses in juvenile monkeys. Neuroendocrinology (1988) 0.92
Receptors and neurosecretory actions of endothelin in hypothalamic neurons. Proc Natl Acad Sci U S A (1991) 0.92
Transgenic mice with pigmented intraocular tumors: tissue of origin and treatment. Invest Ophthalmol Vis Sci (1998) 0.92
Transmembrane signals mediating neural peptide secretion: role of protein kinase C activators and arachidonic acid metabolites in luteinizing hormone-releasing hormone secretion. Endocrinology (1986) 0.92
Tissue-specific gene expression in the pituitary: the glycoprotein hormone alpha-subunit gene is regulated by a gonadotrope-specific protein. Mol Cell Biol (1992) 0.91