PubRank

M J Quon

Author PubWeight™ 67.26‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Quantitative insulin sensitivity check index: a simple, accurate method for assessing insulin sensitivity in humans. J Clin Endocrinol Metab 2000 11.97
2 Insulin-stimulated production of nitric oxide is inhibited by wortmannin. Direct measurement in vascular endothelial cells. J Clin Invest 1996 2.82
3 Roles for insulin receptor, PI3-kinase, and Akt in insulin-signaling pathways related to production of nitric oxide in human vascular endothelial cells. Circulation 2000 2.59
4 Physiological role of Akt in insulin-stimulated translocation of GLUT4 in transfected rat adipose cells. Mol Endocrinol 1997 2.51
5 Insulin-stimulated activation of eNOS is independent of Ca2+ but requires phosphorylation by Akt at Ser(1179). J Biol Chem 2001 2.42
6 Use of bismannose photolabel to elucidate insulin-regulated GLUT4 subcellular trafficking kinetics in rat adipose cells. Evidence that exocytosis is a critical site of hormone action. J Biol Chem 1993 2.41
7 Brain insulin receptors and spatial memory. Correlated changes in gene expression, tyrosine phosphorylation, and signaling molecules in the hippocampus of water maze trained rats. J Biol Chem 1999 1.77
8 Repeatability characteristics of simple indices of insulin resistance: implications for research applications. J Clin Endocrinol Metab 2001 1.71
9 Vasodilator response to systemic but not to local hyperinsulinemia in the human forearm. Hypertension 1998 1.61
10 Tyr(612) and Tyr(632) in human insulin receptor substrate-1 are important for full activation of insulin-stimulated phosphatidylinositol 3-kinase activity and translocation of GLUT4 in adipose cells. Endocrinology 2001 1.56
11 Mutations in the insulin receptor gene. Endocr Rev 1992 1.55
12 Paternal versus maternal transmission of a stimulatory G-protein alpha subunit knockout produces opposite effects on energy metabolism. J Clin Invest 2000 1.51
13 Protein kinase C-zeta phosphorylates insulin receptor substrate-1 and impairs its ability to activate phosphatidylinositol 3-kinase in response to insulin. J Biol Chem 2000 1.50
14 Insulin stimulates both endothelin and nitric oxide activity in the human forearm. Circulation 1999 1.48
15 Caveolin-1 interacts with the insulin receptor and can differentially modulate insulin signaling in transfected Cos-7 cells and rat adipose cells. Mol Endocrinol 1999 1.30
16 Regulation of leptin promoter function by Sp1, C/EBP, and a novel factor. Endocrinology 1998 1.30
17 The mouse obese gene. Genomic organization, promoter activity, and activation by CCAAT/enhancer-binding protein alpha. J Biol Chem 1995 1.29
18 Insulin receptor binding kinetics: modeling and simulation studies. J Theor Biol 2000 1.17
19 Insulin action in vascular endothelium: potential mechanisms linking insulin resistance with hypertension. Diabetes Obes Metab 2000 1.16
20 Phosphorylation of critical serine residues in Gem separates cytoskeletal reorganization from down-regulation of calcium channel activity. Mol Cell Biol 2004 1.16
21 Limitations of the fasting glucose to insulin ratio as an index of insulin sensitivity. J Clin Endocrinol Metab 2001 1.14
22 Protein kinase C-zeta and phosphoinositide-dependent protein kinase-1 are required for insulin-induced activation of ERK in rat adipocytes. J Biol Chem 1999 1.13
23 Phosphorylation of PTP1B at Ser(50) by Akt impairs its ability to dephosphorylate the insulin receptor. Mol Endocrinol 2001 1.12
24 Insulin signalling: metabolic pathways and mechanisms for specificity. Cell Signal 1999 1.07
25 Glucose activates protein kinase C-zeta /lambda through proline-rich tyrosine kinase-2, extracellular signal-regulated kinase, and phospholipase D: a novel mechanism for activating glucose transporter translocation. J Biol Chem 2001 1.06
26 Dependence of insulin-stimulated glucose transporter 4 translocation on 3-phosphoinositide-dependent protein kinase-1 and its target threonine-410 in the activation loop of protein kinase C-zeta. Mol Endocrinol 1999 1.05
27 Okadaic acid activates atypical protein kinase C (zeta/lambda) in rat and 3T3/L1 adipocytes. An apparent requirement for activation of Glut4 translocation and glucose transport. J Biol Chem 1999 1.04
28 Cyclic nucleotide phosphodiesterase 3B is a downstream target of protein kinase B and may be involved in regulation of effects of protein kinase B on thymidine incorporation in FDCP2 cells. J Immunol 2000 1.01
29 Overestimation of minimal model glucose effectiveness in presence of insulin response is due to undermodeling. Am J Physiol 1998 0.99
30 Substitution of isoleucine for methionine at position 1153 in the beta-subunit of the human insulin receptor. A mutation that impairs receptor tyrosine kinase activity, receptor endocytosis, and insulin action. J Biol Chem 1992 0.97
31 Glucose activates mitogen-activated protein kinase (extracellular signal-regulated kinase) through proline-rich tyrosine kinase-2 and the Glut1 glucose transporter. J Biol Chem 2000 0.93
32 Action of insulin receptor substrate-3 (IRS-3) and IRS-4 to stimulate translocation of GLUT4 in rat adipose cells. Mol Endocrinol 1999 0.90
33 Insulin stimulates increased catalytic activity of phosphoinositide-dependent kinase-1 by a phosphorylation-dependent mechanism. Biochemistry 2001 0.90
34 Protein-tyrosine phosphatases PTP1B and syp are modulators of insulin-stimulated translocation of GLUT4 in transfected rat adipose cells. J Biol Chem 1997 0.90
35 Mechanisms of hormone resistance: lessons from insulin-resistant patients. Acta Paediatr Suppl 1994 0.89
36 Insulin receptor substrate-2 (IRS-2) can mediate the action of insulin to stimulate translocation of GLUT4 to the cell surface in rat adipose cells. J Biol Chem 1997 0.89
37 Substitution of glutamic acid for alanine 1135 in the putative "catalytic loop" of the tyrosine kinase domain of the human insulin receptor. A mutation that impairs proteolytic processing into subunits and inhibits receptor tyrosine kinase activity. J Biol Chem 1993 0.89
38 "One-line" preparation of bicarbonate-containing dialysate for use in peritoneal dialysis. Int J Artif Organs 1981 0.88
39 A phosphotyrosyl mimetic peptide reverses impairment of insulin-stimulated translocation of GLUT4 caused by overexpression of PTP1B in rat adipose cells. Biochemistry 1999 0.88
40 Alpha2-Heremans Schmid glycoprotein inhibits insulin-stimulated Elk-1 phosphorylation, but not glucose transport, in rat adipose cells. Endocrinology 1998 0.83
41 PTEN does not modulate GLUT4 translocation in rat adipose cells under physiological conditions. Biochem Biophys Res Commun 2001 0.83
42 Two mutant alleles of the insulin receptor gene in a family with a genetic form of insulin resistance: a 10 base pair deletion in exon 1 and a mutation substituting serine for asparagine-462. Hum Genet 1995 0.79
43 Characterization of a mutant GLUT4 lacking the N-glycosylation site: studies in transfected rat adipose cells. Biochem Biophys Res Commun 1996 0.78
44 Effects of overexpression of glutamine:fructose-6-phosphate amidotransferase (GFAT) and glucosamine treatment on translocation of GLUT4 in rat adipose cells. Mol Cell Endocrinol 1997 0.77
45 Overexpression of protein tyrosine phosphatase-alpha (PTP-alpha) but not PTP-kappa inhibits translocation of GLUT4 in rat adipose cells. Biochem Biophys Res Commun 1999 0.76
46 Peritoneal dialysis using bicarbonate-containing dialysate produced by automated dialysate delivery machine. Artif Organs 1982 0.75
47 Dynamic changes in plasma proinsulin/insulin ratio during insulin secretion influence correlation between radioimmunoassay (RIA) and IMX measurements of insulin. Clin Chim Acta 1999 0.75
48 Obesity modifies the effects of the Asp905Tyr variant of PPP1R3A on risk of type 2 diabetes and insulin sensitivity. Diabetes Obes Metab 2007 0.75
49 Sequential isolated ultrafiltration and dialysis. Int J Artif Organs 1979 0.75
50 A method of deliverying dialysate of constantly decreasing osmolality during dialysis. Artif Organs 1979 0.75
51 Delivering dialysate of constantly decreasing sodium concentration using an automated dialysate delivery machine. Int J Artif Organs 1980 0.75
52 Preparation of bicarbonate-containing peritoneal dialysate using an automated dialysate delivery system. Int J Artif Organs 1981 0.75