PubRank

L Graeve

Author PubWeight™ 60.64‹?›

Top papers

Rank Title Journal Year PubWeight™‹?›
1 Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway. Biochem J 1998 7.15
2 Polarized apical distribution of glycosyl-phosphatidylinositol-anchored proteins in a renal epithelial cell line. Proc Natl Acad Sci U S A 1988 3.19
3 Integral and peripheral protein composition of the apical and basolateral membrane domains in MDCK cells. J Membr Biol 1989 2.65
4 The soluble human IL-6 receptor. Mutational characterization of the proteolytic cleavage site. J Immunol 1994 2.26
5 The soluble interleukin-6 receptor is generated by shedding. Eur J Immunol 1993 2.01
6 Differential activation of acute phase response factor/STAT3 and STAT1 via the cytoplasmic domain of the interleukin 6 signal transducer gp130. I. Definition of a novel phosphotyrosine motif mediating STAT1 activation. J Biol Chem 1996 1.88
7 A di-leucine motif and an upstream serine in the interleukin-6 (IL-6) signal transducer gp130 mediate ligand-induced endocytosis and down-regulation of the IL-6 receptor. J Biol Chem 1996 1.47
8 LPS and TNFalpha induce SOCS3 mRNA and inhibit IL-6-induced activation of STAT3 in macrophages. FEBS Lett 1999 1.46
9 Differential activation of acute phase response factor/Stat3 and Stat1 via the cytoplasmic domain of the interleukin 6 signal transducer gp130. II. Src homology SH2 domains define the specificity of stat factor activation. J Biol Chem 1996 1.40
10 Structure-function analysis of interleukin-6 utilizing human/murine chimeric molecules. Involvement of two separate domains in receptor binding. J Biol Chem 1993 1.18
11 Soluble IL-6 receptor potentiates the antagonistic activity of soluble gp130 on IL-6 responses. J Immunol 1998 1.13
12 Activation of the Janus kinase/signal transducer and activator of transcription pathway by osmotic shock. J Biol Chem 1998 1.11
13 Differential shedding of the two subunits of the interleukin-6 receptor. FEBS Lett 1993 1.10
14 Identification of the interleukin-6/oncostatin M response element in the rat tissue inhibitor of metalloproteinases-1 (TIMP-1) promoter. Nucleic Acids Res 1995 1.04
15 The hepatic interleukin-6 receptor. Down-regulation of the interleukin-6 binding subunit (gp80) by its ligand. FEBS Lett 1992 1.03
16 The soluble glycoprotein of vesicular stomatitis virus is formed during or shortly after the translation process. J Virol 1986 1.01
17 The mitogen-activated protein (MAP) kinase p38 and its upstream activator MAP kinase kinase 6 are involved in the activation of signal transducer and activator of transcription by hyperosmolarity. J Biol Chem 1999 0.99
18 The inhibition of interleukin-6-dependent STAT activation by mitogen-activated protein kinases depends on tyrosine 759 in the cytoplasmic tail of glycoprotein 130. J Biol Chem 2000 0.99
19 Biosynthesis and half-life of the interleukin-6 receptor and its signal transducer gp130. Eur J Biochem 1994 0.98
20 Internalization of the interleukin 6 signal transducer gp130 does not require activation of the Jak/STAT pathway. Biochem J 1998 0.97
21 Identification of a region within the cytoplasmic domain of the interleukin-6 (IL-6) signal transducer gp130 important for ligand-induced endocytosis of the IL-6 receptor. J Biol Chem 1994 0.97
22 Interleukin-6 and related cytokines: effect on the acute phase reaction. Z Ernahrungswiss 1998 0.96
23 Evidence for nuclear targeting of prothymosin and parathymosin synthesized in situ. Proc Natl Acad Sci U S A 1991 0.94
24 Constitutive internalization and association with adaptor protein-2 of the interleukin-6 signal transducer gp130. FEBS Lett 1998 0.93
25 TIMP-1 protein expression is stimulated by IL-1 beta and IL-6 in primary rat hepatocytes. FEBS Lett 1994 0.92
26 Regulation of tissue inhibitor of metalloproteinases-1 gene expression by cytokines and dexamethasone in rat hepatocyte primary cultures. Hepatology 1993 0.92
27 Intracellular retention of interleukin-6 abrogates signaling. J Biol Chem 1993 0.92
28 Identification of a Leu-lle internalization motif within the cytoplasmic domain of the leukaemia inhibitory factor receptor. Biochem J 1999 0.92
29 A single STAT recruitment module in a chimeric cytokine receptor complex is sufficient for STAT activation. J Biol Chem 1997 0.90
30 Methods to estimate the polarized distribution of surface antigens in cultured epithelial cells. Methods Cell Biol 1989 0.89
31 Comparative study on the phosphotyrosine motifs of different cytokine receptors involved in STAT5 activation. FEBS Lett 1996 0.89
32 Oncostatin M differentially regulates tissue inhibitors of metalloproteinases TIMP-1 and TIMP-3 gene expression in human synovial lining cells. Eur J Biochem 1996 0.88
33 Activity and PI3-kinase dependent trafficking of the intestinal anion exchanger downregulated in adenoma depend on its PDZ interaction and on lipid rafts. Am J Physiol Gastrointest Liver Physiol 2010 0.86
34 Termination of IL-6-induced STAT activation is independent of receptor internalization but requires de novo protein synthesis. FEBS Lett 2000 0.86
35 Synthesis of tissue inhibitor of metalloproteinase-1 (TIMP-1) in human hepatoma cells (HepG2). Up-regulation by interleukin-6 and transforming growth factor beta 1. FEBS Lett 1992 0.86
36 Regulation of beta2-microglobulin expression in different human cell lines by proinflammatory cytokines. Nephrol Dial Transplant 1999 0.85
37 Tissue inhibitor of metalloproteinases-2 (TIMP-2) in rat liver cells is increased by lipopolysaccharide and prostaglandin E2. FEBS Lett 1995 0.85
38 The vesicular stomatitis virus matrix protein inhibits glycoprotein 130-dependent STAT activation. J Immunol 2001 0.84
39 The PDZ-interaction of the intestinal anion exchanger downregulated in adenoma (DRA; SLC26A3) facilitates its movement into Rab11a-positive recycling endosomes. Am J Physiol Gastrointest Liver Physiol 2013 0.83
40 Induction of alpha1-antitrypsin synthesis in human articular chondrocytes by interleukin-6-type cytokines: evidence for a local acute-phase response in the joint. Arthritis Rheum 1999 0.82
41 The inhibitory effect of IL-1 beta on IL-6-induced alpha 2-macroglobulin expression is due to activation of NF-kappa B. J Immunol 2001 0.82
42 Membrane-bound and soluble interleukin-6 receptor: studies on structure, regulation of expression, and signal transduction. Ann N Y Acad Sci 1995 0.82
43 Regulation of interleukin-6 receptor expression by interleukin-6 in human monocytes--a re-examination. FEBS Lett 1994 0.81
44 The cytoplasmic domain of the interleukin-6 receptor gp80 mediates its basolateral sorting in polarized madin-darby canine kidney cells. J Cell Sci 2000 0.80
45 The hepatic interleukin-6 receptor. Studies on its structure and regulation by phorbol 12-myristate 13-acetate-dexamethasone. J Biol Chem 1993 0.80
46 Differential inhibition of IL-6-type cytokine-induced STAT activation by PMA. FEBS Lett 2000 0.79
47 Expression of a biologically active murine tissue inhibitor of metalloproteinases-1 (TIMP-1) in baculovirus-infected insect cells. Purification and tissue distribution in the rat. Eur J Biochem 1995 0.79
48 [Cell endocytosis of the complex interleukin-6-soluble interleukin-6 receptor and its intralysosomal degradation]. Biull Eksp Biol Med 1997 0.78
49 Fractionation of biologically active messenger RNAs by HPLC gel filtration. Biochem Biophys Res Commun 1982 0.77
50 Termination and modulation of IL-6-type cytokine signaling. Adv Exp Med Biol 2001 0.77
51 Quiescence of CD34-negative haematopoietic stem cells is mediated by downregulation of Cyclin B and no stat activation. Cytokine 2000 0.77
52 In vitro-generated stem cell leukaemia showing altered cell cycle progression with distinct signalling of the tyrosine-phosphorylated rasGAP-associated p62(dok) protein. J Pathol 2000 0.75
53 Modulation and termination of interleukin-6 signalling. Eur Cytokine Netw 2000 0.75
54 A region within the cytoplasmic domain of the interleukin-6 signal transducer gp130 important for ligand-induced endocytosis of the IL-6 receptor. Ann N Y Acad Sci 1995 0.75
55 Purification of low-molecular-weight RNAs by high-performance gel permeation chromatography. J Chromatogr 1983 0.75
56 Expression of interleukin-6 receptor subunits in human macrophage subsets. Int Arch Allergy Immunol 1997 0.75
57 TIMP-1 protein expression is stimulated by IL-1 beta and IL-6 in primary rat hepatocytes. Ann N Y Acad Sci 1995 0.75