Published in J Membr Biol on March 01, 1989
Signal transducing molecules and glycosyl-phosphatidylinositol-linked proteins form a caveolin-rich insoluble complex in MDCK cells. J Cell Biol (1993) 6.62
Biochemical analysis of connexin43 intracellular transport, phosphorylation, and assembly into gap junctional plaques. J Cell Biol (1991) 3.76
Identification of a 160-kDa polypeptide that binds to the tight junction protein ZO-1. Proc Natl Acad Sci U S A (1991) 3.60
A glycophospholipid membrane anchor acts as an apical targeting signal in polarized epithelial cells. J Cell Biol (1989) 3.56
Localization of inositol 1,4,5-trisphosphate receptor-like protein in plasmalemmal caveolae. J Cell Biol (1992) 2.72
Endocytosis in filter-grown Madin-Darby canine kidney cells. J Cell Biol (1989) 2.65
Vectorial targeting of apical and basolateral plasma membrane proteins in a human adenocarcinoma epithelial cell line. Proc Natl Acad Sci U S A (1989) 2.36
Depolarization and cAMP elevation rapidly recruit TrkB to the plasma membrane of CNS neurons. Neuron (1998) 2.18
Caveolin forms a hetero-oligomeric protein complex that interacts with an apical GPI-linked protein: implications for the biogenesis of caveolae. J Cell Biol (1993) 2.17
The O-glycosylated stalk domain is required for apical sorting of neurotrophin receptors in polarized MDCK cells. J Cell Biol (1997) 2.14
Vectorial targeting of an endogenous apical membrane sialoglycoprotein and uvomorulin in MDCK cells. J Cell Biol (1990) 2.12
The membrane-proximal intracytoplasmic tyrosine residue of HIV-1 envelope glycoprotein is critical for basolateral targeting of viral budding in MDCK cells. EMBO J (1997) 2.10
WIF-B cells: an in vitro model for studies of hepatocyte polarity. J Cell Biol (1993) 2.04
Biogenetic pathways of plasma membrane proteins in Caco-2, a human intestinal epithelial cell line. J Cell Biol (1990) 2.02
AP1B sorts basolateral proteins in recycling and biosynthetic routes of MDCK cells. Proc Natl Acad Sci U S A (2007) 1.92
A CD317/tetherin-RICH2 complex plays a critical role in the organization of the subapical actin cytoskeleton in polarized epithelial cells. J Cell Biol (2009) 1.90
An internal deletion in the cytoplasmic tail reverses the apical localization of human NGF receptor in transfected MDCK cells. J Cell Biol (1991) 1.87
Glycosylphosphatidylinositol-anchored proteins are preferentially targeted to the basolateral surface in Fischer rat thyroid epithelial cells. J Cell Biol (1993) 1.78
VIP21/caveolin, glycosphingolipid clusters and the sorting of glycosylphosphatidylinositol-anchored proteins in epithelial cells. EMBO J (1994) 1.75
Microtubular organization and its involvement in the biogenetic pathways of plasma membrane proteins in Caco-2 intestinal epithelial cells. J Cell Biol (1991) 1.74
Steady-state distribution and biogenesis of endogenous Madin-Darby canine kidney glycoproteins: evidence for intracellular sorting and polarized cell surface delivery. J Cell Biol (1989) 1.71
Basolateral targeting and microtubule-dependent transcytosis of the aquaporin-2 water channel. Am J Physiol Cell Physiol (2012) 1.60
Helicobacter pylori perturbs iron trafficking in the epithelium to grow on the cell surface. PLoS Pathog (2011) 1.57
Transcytosis in MDCK cells: identification of glycoproteins transported bidirectionally between both plasma membrane domains. J Cell Biol (1990) 1.57
Vectorial apical delivery and slow endocytosis of a glycolipid-anchored fusion protein in transfected MDCK cells. Proc Natl Acad Sci U S A (1990) 1.56
Surface expression of epithelial Na channel protein in rat kidney. J Gen Physiol (2008) 1.51
Caveolin transfection results in caveolae formation but not apical sorting of glycosylphosphatidylinositol (GPI)-anchored proteins in epithelial cells. J Cell Biol (1998) 1.51
Remodeling the cell surface distribution of membrane proteins during the development of epithelial cell polarity. J Cell Biol (1992) 1.48
The clathrin adaptor AP-1A mediates basolateral polarity. Dev Cell (2012) 1.47
Transcytosis of cholera toxin subunits across model human intestinal epithelia. Proc Natl Acad Sci U S A (1995) 1.46
Modulation of transcytotic and direct targeting pathways in a polarized thyroid cell line. EMBO J (1992) 1.44
Polarized endocytosis by Madin-Darby canine kidney cells transfected with functional chicken liver glycoprotein receptor. J Cell Biol (1989) 1.40
Parathyroid hormone leads to the lysosomal degradation of the renal type II Na/Pi cotransporter. Proc Natl Acad Sci U S A (1998) 1.29
A cadherin-like protein in eggs and cleaving embryos of Xenopus laevis is expressed in oocytes in response to progesterone. J Cell Biol (1990) 1.27
The internalization signal and the phosphorylation site of transferrin receptor are distinct from the main basolateral sorting information. EMBO J (1993) 1.27
Plasticity in epithelial cell phenotype: modulation by expression of different cadherin cell adhesion molecules. J Cell Biol (1995) 1.26
Mannosamine, a novel inhibitor of glycosylphosphatidylinositol incorporation into proteins. EMBO J (1991) 1.25
Intracellular retention of glycosylphosphatidyl inositol-linked proteins in caveolin-deficient cells. Mol Cell Biol (2002) 1.25
The MAL proteolipid is necessary for the overall apical delivery of membrane proteins in the polarized epithelial Madin-Darby canine kidney and fischer rat thyroid cell lines. Mol Biol Cell (2000) 1.23
TGN38 recycles basolaterally in polarized Madin-Darby canine kidney cells. Mol Biol Cell (1994) 1.20
Heparan sulfate expression in polarized epithelial cells: the apical sorting of glypican (GPI-anchored proteoglycan) is inversely related to its heparan sulfate content. J Cell Biol (1996) 1.15
Cell surface transport, oligomerization, and endocytosis of chimeric type II glycoproteins: role of cytoplasmic and anchor domains. Mol Cell Biol (1991) 1.09
Functional activation of plasma membrane anion exchangers occurs in a pre-Golgi compartment. J Cell Biol (1993) 1.08
Proinflammatory cytokine secretion is suppressed by TMEM16A or CFTR channel activity in human cystic fibrosis bronchial epithelia. Mol Biol Cell (2012) 1.07
Hepatocyte polarity. Compr Physiol (2013) 1.06
Apical polarization of N-CAM in retinal pigment epithelium is dependent on contact with the neural retina. J Cell Biol (1993) 1.04
Actin is a surface component of calf pulmonary artery endothelial cells in culture. Proc Natl Acad Sci U S A (1993) 1.02
Mechanisms of plasma membrane protein degradation: recycling proteins are degraded more rapidly than those confined to the cell surface. Proc Natl Acad Sci U S A (1991) 1.01
Opposite polarity of virus budding and of viral envelope glycoprotein distribution in epithelial cells derived from different tissues. J Cell Biol (1992) 1.00
Enhanced antigen presentation in the absence of the invariant chain endosomal localization signal. J Exp Med (1993) 0.96
Priority targeting of glycosyl-phosphatidylinositol-anchored proteins to the bile-canalicular (apical) plasma membrane of hepatocytes. Involvement of 'late' endosomes. Biochem J (1990) 0.93
Interaction with mLin-7 alters the targeting of endocytosed transmembrane proteins in mammalian epithelial cells. Mol Biol Cell (2001) 0.93
Basolateral sorting signals regulating tissue-specific polarity of heteromeric monocarboxylate transporters in epithelia. Traffic (2011) 0.93
Apical and basolateral transferrin receptors in polarized BeWo cells recycle through separate endosomes. J Cell Biol (1991) 0.92
Plasma membrane protein polarity and trafficking in RPE cells: past, present and future. Exp Eye Res (2014) 0.89
Polarized intestinal hybrid cell lines derived from primary culture: establishment and characterization. Proc Natl Acad Sci U S A (1991) 0.89
Overcoming key technological challenges in using mass spectrometry for mapping cell surfaces in tissues. Mol Cell Proteomics (2010) 0.84
Direct targeting of neutral endopeptidase (EC 3.4.24.11) to the apical cell surface of transfected LLC-PK1 cells and unpolarized secretion of its soluble form. Biochem J (1995) 0.84
Functional reconstitution, membrane targeting, genomic structure, and chromosomal localization of a human urate transporter. J Clin Invest (2001) 0.83
Identification of a critical basic residue on the ecotropic murine leukemia virus receptor. J Virol (2003) 0.83
Chronic hyperosmolality increases NHE3 activity in OKP cells. J Clin Invest (1998) 0.82
Targeting and imaging signature caveolar molecules in lungs. Proc Am Thorac Soc (2009) 0.81
Identification of a putative tyrosine-O-sulphate (TyrS) receptor possibly functioning in the biosynthetic transport of tyrosine-sulphated proteins in Madin-Darby canine kidney cells. Biochem J (1993) 0.80
The post-synthetic sorting of endogenous membrane proteins examined by the simultaneous purification of apical and basolateral plasma membrane fractions from Caco-2 cells. Biochem J (1992) 0.80
Differential effects of ethanol on glycine uptake mediated by the recombinant GLYT1 and GLYT2 glycine transporters. Br J Pharmacol (2000) 0.79
Regulation of renal Na+/HCO3- cotransporter stimulation by CO2: role of phosphorylation, exocytosis and protein synthesis. J Membr Biol (2004) 0.78
Cdo Regulates Surface Expression of Kir2.1 K+ Channel in Myoblast Differentiation. PLoS One (2016) 0.77
Asymmetrical distribution of L-isoaspartyl protein carboxyl methyltransferases in the plasma membranes of rat kidney cortex. Biochem J (1994) 0.77
Basolateral sorting of chloride channel 2 is mediated by interactions between a dileucine motif and the clathrin adaptor AP-1. Mol Biol Cell (2015) 0.77
Role of a putative tyrosine-O-sulfate receptor in the targeting and/or intracellular transport of tyrosine-sulfated proteins. Cytotechnology (1997) 0.75
Interleukin-6-type cytokine signalling through the gp130/Jak/STAT pathway. Biochem J (1998) 7.15
Sec6/8 complex is recruited to cell-cell contacts and specifies transport vesicle delivery to the basal-lateral membrane in epithelial cells. Cell (1998) 4.80
A glycophospholipid membrane anchor acts as an apical targeting signal in polarized epithelial cells. J Cell Biol (1989) 3.56
Polarized apical distribution of glycosyl-phosphatidylinositol-anchored proteins in a renal epithelial cell line. Proc Natl Acad Sci U S A (1988) 3.19
Phagocytosis of rod outer segments by retinal pigment epithelial cells requires alpha(v)beta5 integrin for binding but not for internalization. Proc Natl Acad Sci U S A (1997) 2.99
Viral glycoproteins destined for apical or basolateral plasma membrane domains traverse the same Golgi apparatus during their intracellular transport in doubly infected Madin-Darby canine kidney cells. J Cell Biol (1984) 2.93
ERBIN: a basolateral PDZ protein that interacts with the mammalian ERBB2/HER2 receptor. Nat Cell Biol (2000) 2.90
Biogenesis of epithelial cell polarity: intracellular sorting and vectorial exocytosis of an apical plasma membrane glycoprotein. Cell (1984) 2.60
Formation of the apical pole of epithelial (Madin-Darby canine kidney) cells: polarity of an apical protein is independent of tight junctions while segregation of a basolateral marker requires cell-cell interactions. J Cell Biol (1987) 2.55
Kinesin and dynamin are required for post-Golgi transport of a plasma-membrane protein. Nat Cell Biol (2000) 2.37
Catenins and zonula occludens-1 form a complex during early stages in the assembly of tight junctions. J Cell Biol (1996) 2.37
Vectorial targeting of apical and basolateral plasma membrane proteins in a human adenocarcinoma epithelial cell line. Proc Natl Acad Sci U S A (1989) 2.36
Glycophospholipid membrane anchoring provides clues to the mechanism of protein sorting in polarized epithelial cells. Trends Biochem Sci (1990) 2.27
The soluble human IL-6 receptor. Mutational characterization of the proteolytic cleavage site. J Immunol (1994) 2.26
The O-glycosylated stalk domain is required for apical sorting of neurotrophin receptors in polarized MDCK cells. J Cell Biol (1997) 2.14
Vectorial targeting of an endogenous apical membrane sialoglycoprotein and uvomorulin in MDCK cells. J Cell Biol (1990) 2.12
Microtubules and actin filaments are not critically involved in the biogenesis of epithelial cell surface polarity. J Cell Biol (1986) 2.12
Intracellular transport of influenza virus hemagglutinin to the apical surface of Madin-Darby canine kidney cells. J Cell Biol (1984) 2.08
Transport of vesicular stomatitis virus G protein to the cell surface is signal mediated in polarized and nonpolarized cells. J Cell Biol (1996) 2.06
Biogenetic pathways of plasma membrane proteins in Caco-2, a human intestinal epithelial cell line. J Cell Biol (1990) 2.02
The soluble interleukin-6 receptor is generated by shedding. Eur J Immunol (1993) 2.01
cdc42 regulates the exit of apical and basolateral proteins from the trans-Golgi network. EMBO J (2001) 2.00
Caveolin-2 localizes to the golgi complex but redistributes to plasma membrane, caveolae, and rafts when co-expressed with caveolin-1. J Biol Chem (1999) 2.00
Dynein- and microtubule-mediated translocation of adenovirus serotype 5 occurs after endosomal lysis. Hum Gene Ther (2000) 1.97
An internal deletion in the cytoplasmic tail reverses the apical localization of human NGF receptor in transfected MDCK cells. J Cell Biol (1991) 1.87
Identification of CD146 as a component of the endothelial junction involved in the control of cell-cell cohesion. Blood (2001) 1.86
Glycosylation does not determine segregation of viral envelope proteins in the plasma membrane of epithelial cells. J Cell Biol (1981) 1.83
Assembly of enveloped viruses in Madin-Darby canine kidney cells: polarized budding from single attached cells and from clusters of cells in suspension. J Cell Biol (1983) 1.82
An endogenous MDCK lysosomal membrane glycoprotein is targeted basolaterally before delivery to lysosomes. J Cell Biol (1991) 1.81
Expression of caveolin-1 is required for the transport of caveolin-2 to the plasma membrane. Retention of caveolin-2 at the level of the golgi complex. J Biol Chem (1999) 1.79
Myosin II is involved in the production of constitutive transport vesicles from the TGN. J Cell Biol (1997) 1.78
Glycosylphosphatidylinositol-anchored proteins are preferentially targeted to the basolateral surface in Fischer rat thyroid epithelial cells. J Cell Biol (1993) 1.78
Preferred apical distribution of glycosyl-phosphatidylinositol (GPI) anchored proteins: a highly conserved feature of the polarized epithelial cell phenotype. J Membr Biol (1990) 1.76
VIP21/caveolin, glycosphingolipid clusters and the sorting of glycosylphosphatidylinositol-anchored proteins in epithelial cells. EMBO J (1994) 1.75
Characterization of the ribosomal binding site in rat liver rough microsomes: ribophorins I and II, two integral membrane proteins related to ribosome binding. J Supramol Struct (1978) 1.75
Microtubular organization and its involvement in the biogenetic pathways of plasma membrane proteins in Caco-2 intestinal epithelial cells. J Cell Biol (1991) 1.74
The epithelial polarity program: machineries involved and their hijacking by cancer. Oncogene (2008) 1.72
Steady-state distribution and biogenesis of endogenous Madin-Darby canine kidney glycoproteins: evidence for intracellular sorting and polarized cell surface delivery. J Cell Biol (1989) 1.71
Modulation of the expression of an apical plasma membrane protein of Madin-Darby canine kidney epithelial cells: cell-cell interactions control the appearance of a novel intracellular storage compartment. J Cell Biol (1987) 1.61
The large external domain is sufficient for the correct sorting of secreted or chimeric influenza virus hemagglutinins in polarized monkey kidney cells. J Cell Biol (1987) 1.59
Immortalization of polarized rat retinal pigment epithelium. J Cell Sci (1993) 1.57
Vectorial apical delivery and slow endocytosis of a glycolipid-anchored fusion protein in transfected MDCK cells. Proc Natl Acad Sci U S A (1990) 1.56
Exocytosis of vacuolar apical compartment (VAC): a cell-cell contact controlled mechanism for the establishment of the apical plasma membrane domain in epithelial cells. J Cell Biol (1988) 1.52
Caveolin transfection results in caveolae formation but not apical sorting of glycosylphosphatidylinositol (GPI)-anchored proteins in epithelial cells. J Cell Biol (1998) 1.51
A di-leucine motif and an upstream serine in the interleukin-6 (IL-6) signal transducer gp130 mediate ligand-induced endocytosis and down-regulation of the IL-6 receptor. J Biol Chem (1996) 1.47
LPS and TNFalpha induce SOCS3 mRNA and inhibit IL-6-induced activation of STAT3 in macrophages. FEBS Lett (1999) 1.46
Ezrin promotes morphogenesis of apical microvilli and basal infoldings in retinal pigment epithelium. J Cell Biol (1999) 1.46
Polarized assembly of enveloped viruses from cultured epithelial cells. Methods Enzymol (1983) 1.45
Modulation of transcytotic and direct targeting pathways in a polarized thyroid cell line. EMBO J (1992) 1.44
Correctly sorted molecules of a GPI-anchored protein are clustered and immobile when they arrive at the apical surface of MDCK cells. J Cell Biol (1993) 1.41
Polarized endocytosis by Madin-Darby canine kidney cells transfected with functional chicken liver glycoprotein receptor. J Cell Biol (1989) 1.40
A polarized epithelial cell mutant deficient in translocation of UDP-galactose into the Golgi complex. J Biol Chem (1988) 1.39
GPI-anchored proteins associate to form microdomains during their intracellular transport in Caco-2 cells. J Cell Sci (1993) 1.36
Use of the ARPE-19 cell line as a model of RPE polarity: basolateral secretion of FGF5. Invest Ophthalmol Vis Sci (1998) 1.32
Selective control of basolateral membrane protein polarity by cdc42. Traffic (2001) 1.29
Apical polarity of Na,K-ATPase in retinal pigment epithelium is linked to a reversal of the ankyrin-fodrin submembrane cytoskeleton. J Cell Biol (1991) 1.27
The internalization signal and the phosphorylation site of transferrin receptor are distinct from the main basolateral sorting information. EMBO J (1993) 1.27
Plasticity in epithelial cell phenotype: modulation by expression of different cadherin cell adhesion molecules. J Cell Biol (1995) 1.26
Mannosamine, a novel inhibitor of glycosylphosphatidylinositol incorporation into proteins. EMBO J (1991) 1.25
The glycosylphosphatidyl inositol-anchored adhesion molecule F3/contactin is required for surface transport of paranodin/contactin-associated protein (caspr). J Cell Biol (2000) 1.24
Emerging functional roles for the glycosyl-phosphatidylinositol membrane protein anchor. J Membr Biol (1990) 1.24
Development of polarity in cerebellar granule neurons. J Neurobiol (1997) 1.22
TGN38 recycles basolaterally in polarized Madin-Darby canine kidney cells. Mol Biol Cell (1994) 1.20
Saturation of, and competition for entry into, the apical secretory pathway. Proc Natl Acad Sci U S A (2000) 1.20
Detergent-resistant membrane microdomains from Caco-2 cells do not contain caveolin. Am J Physiol (1996) 1.20
Structure-function analysis of interleukin-6 utilizing human/murine chimeric molecules. Involvement of two separate domains in receptor binding. J Biol Chem (1993) 1.18
Apical polarity of N-CAM and EMMPRIN in retinal pigment epithelium resulting from suppression of basolateral signal recognition. J Cell Biol (1998) 1.17
Delivery of Na+,K(+)-ATPase in polarized epithelial cells. Science (1993) 1.16
The ERBB2/HER2 receptor differentially interacts with ERBIN and PICK1 PSD-95/DLG/ZO-1 domain proteins. J Biol Chem (2001) 1.16
Selective anchoring in the specific plasma membrane domain: a role in epithelial cell polarity. J Cell Biol (1988) 1.16
Targeting of transmembrane and GPI-anchored forms of N-CAM to opposite domains of a polarized epithelial cell. Nature (1991) 1.15
Insulin-stimulated release of lipoprotein lipase by metabolism of its phosphatidylinositol anchor. Science (1988) 1.15
Soluble IL-6 receptor potentiates the antagonistic activity of soluble gp130 on IL-6 responses. J Immunol (1998) 1.13
Human syntaxin 3 is localized apically in human intestinal cells. J Cell Sci (1997) 1.11
Activation of the Janus kinase/signal transducer and activator of transcription pathway by osmotic shock. J Biol Chem (1998) 1.11
The neural cell adhesion molecule expresses a tyrosine-independent basolateral sorting signal. J Biol Chem (1997) 1.11
The role of phosphorylation in development of tight junctions in cultured renal epithelial (MDCK) cells. Biochem Biophys Res Commun (1991) 1.10
Differential shedding of the two subunits of the interleukin-6 receptor. FEBS Lett (1993) 1.10
Changes in intracellular calcium during the development of epithelial polarity and junctions. Proc Natl Acad Sci U S A (1992) 1.08
The polarity of the plasma membrane protein RET-PE2 in retinal pigment epithelium is developmentally regulated. J Cell Sci (1996) 1.07
Brefeldin A causes structural and functional alterations of the trans-Golgi network of MDCK cells. J Cell Sci (1994) 1.06
Porin is present in the plasma membrane where it is concentrated in caveolae and caveolae-related domains. J Biol Chem (1999) 1.06
Polarized expression of functional rat liver asialoglycoprotein receptor in transfected Madin-Darby canine kidney cells. J Biol Chem (1990) 1.05
Identification of the interleukin-6/oncostatin M response element in the rat tissue inhibitor of metalloproteinases-1 (TIMP-1) promoter. Nucleic Acids Res (1995) 1.04
Apical polarization of N-CAM in retinal pigment epithelium is dependent on contact with the neural retina. J Cell Biol (1993) 1.04
Isolation and characterization of the apical surface of polarized Madin-Darby canine kidney epithelial cells. Proc Natl Acad Sci U S A (1988) 1.04
The hepatic interleukin-6 receptor. Down-regulation of the interleukin-6 binding subunit (gp80) by its ligand. FEBS Lett (1992) 1.03
Fusion proteins containing a minimal GPI-attachment signal are apically expressed in transfected MDCK cells. J Cell Sci (1991) 1.02
The soluble glycoprotein of vesicular stomatitis virus is formed during or shortly after the translation process. J Virol (1986) 1.01