Published in Genomics on October 01, 1992
Cloning and expression in Escherichia coli of a dog thyroid cDNA encoding a novel inositol 1,4,5-trisphosphate 5-phosphatase. Biochem J (1994) 0.95
Human inositol 1,4,5-trisphosphate 3-kinase isoform B (IP3KB) is a nucleocytoplasmic shuttling protein specifically enriched at cortical actin filaments and at invaginations of the nuclear envelope. J Biol Chem (2010) 0.84
Resistance to HIV-1 infection in caucasian individuals bearing mutant alleles of the CCR-5 chemokine receptor gene. Nature (1996) 15.91
A sequence in M13 phage detects hypervariable minisatellites in human and animal DNA. Science (1987) 7.20
Selective amplification and cloning of four new members of the G protein-coupled receptor family. Science (1989) 6.67
A new member of the immunoglobulin superfamily--CTLA-4. Nature (1987) 5.10
Linkage of Marfan syndrome and a phenotypically related disorder to two different fibrillin genes. Nature (1991) 4.77
The metastasis suppressor gene KiSS-1 encodes kisspeptins, the natural ligands of the orphan G protein-coupled receptor GPR54. J Biol Chem (2001) 4.77
Molecular cloning and functional expression of a new human CC-chemokine receptor gene. Biochemistry (1996) 4.35
Unresponsiveness to cannabinoids and reduced addictive effects of opiates in CB1 receptor knockout mice. Science (1999) 4.31
ORL1, a novel member of the opioid receptor family. Cloning, functional expression and localization. FEBS Lett (1994) 3.78
Aggressiveness, hypoalgesia and high blood pressure in mice lacking the adenosine A2a receptor. Nature (1997) 3.75
Programmed cell death is affected in the novel mouse mutant Fused toes (Ft). Development (1994) 3.71
Regions in beta-chemokine receptors CCR5 and CCR2b that determine HIV-1 cofactor specificity. Cell (1996) 3.44
Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas. Nature (1993) 3.19
Thyroid nuclear factor 1 (TTF-1) contains a homeodomain and displays a novel DNA binding specificity. EMBO J (1990) 2.97
The characterization of the promoter of the gene encoding the p50 subunit of NF-kappa B indicates that it participates in its own regulation. EMBO J (1992) 2.86
Cloning of two human thyroid cDNAs encoding new members of the NADPH oxidase family. J Biol Chem (2000) 2.70
DNA probe localization at 18p113 band by in situ hybridization and identification of a small supernumerary chromosome. Hum Genet (1985) 2.59
The chemokine TECK is expressed by thymic and intestinal epithelial cells and attracts double- and single-positive thymocytes expressing the TECK receptor CCR9. Eur J Immunol (2000) 2.58
A novel lysosome-associated membrane glycoprotein, DC-LAMP, induced upon DC maturation, is transiently expressed in MHC class II compartment. Immunity (1998) 2.56
Isolation and characterization of Suv39h2, a second histone H3 methyltransferase gene that displays testis-specific expression. Mol Cell Biol (2000) 2.56
A new member of the Rho family, Rnd1, promotes disassembly of actin filament structures and loss of cell adhesion. J Cell Biol (1998) 2.36
Cloning and chromosomal localization of human genes encoding the three chains of type VI collagen. Am J Hum Genet (1988) 2.34
Molecular cloning of the thyrotropin receptor. Science (1989) 2.32
Close linkage of fragile X-mental retardation syndrome to haemophilia B and transmission through a normal male. Nature (1984) 2.28
Cloning and primary sequence of a mouse candidate prohormone convertase PC1 homologous to PC2, Furin, and Kex2: distinct chromosomal localization and messenger RNA distribution in brain and pituitary compared to PC2. Mol Endocrinol (1991) 2.26
Constitutional chromosomal breakage. Hum Genet (1976) 2.24
Molecular cloning of a human cannabinoid receptor which is also expressed in testis. Biochem J (1991) 2.23
Characterization of the HST-related FGF.6 gene, a new member of the fibroblast growth factor gene family. Oncogene (1989) 2.20
The human PRR2 gene, related to the human poliovirus receptor gene (PVR), is the true homolog of the murine MPH gene. Gene (1995) 2.19
Nitric oxide synthase activity in infantile hypertrophic pyloric stenosis. N Engl J Med (1992) 2.14
Complementary DNA characterization and chromosomal localization of a human gene related to the poliovirus receptor-encoding gene. Gene (1995) 2.11
X-autosome translocations: cytogenetic characteristics and their consequences. Hum Genet (1982) 2.09
A novel putative receptor protein tyrosine kinase of the met family. Oncogene (1993) 2.06
TIF1gamma, a novel member of the transcriptional intermediary factor 1 family. Oncogene (1999) 2.05
Identification of four novel human genes amplified and overexpressed in breast carcinoma and localized to the q11-q21.3 region of chromosome 17. Genomics (1995) 1.96
Primary structure of bovine thyroglobulin deduced from the sequence of its 8,431-base complementary DNA. Nature (1985) 1.96
Genetic control of diabetes progression. Immunity (1997) 1.95
RDC8 codes for an adenosine A2 receptor with physiological constitutive activity. Biochem Biophys Res Commun (1990) 1.94
ChemR23, a putative chemoattractant receptor, is expressed in monocyte-derived dendritic cells and macrophages and is a coreceptor for SIV and some primary HIV-1 strains. Eur J Immunol (1998) 1.88
The human necdin gene, NDN, is maternally imprinted and located in the Prader-Willi syndrome chromosomal region. Nat Genet (1997) 1.88
Regional expression of the homeobox gene Nkx-2.2 in the developing mammalian forebrain. Neuron (1992) 1.85
Characterization of Spi-B, a transcription factor related to the putative oncoprotein Spi-1/PU.1. Mol Cell Biol (1992) 1.81
Hox-5.1 defines a homeobox-containing gene locus on mouse chromosome 2. Proc Natl Acad Sci U S A (1988) 1.79
CCR5 binds multiple CC-chemokines: MCP-3 acts as a natural antagonist. Blood (1999) 1.75
A mouse model for hereditary thyroid dysgenesis and cleft palate. Nat Genet (1998) 1.74
A novel, secreted form of human ADAM 12 (meltrin alpha) provokes myogenesis in vivo. J Biol Chem (1998) 1.70
Human elastin gene: new evidence for localization to the long arm of chromosome 7. Am J Hum Genet (1991) 1.69
Human 27-kDa calbindin complementary DNA sequence. Evolutionary and functional implications. Eur J Biochem (1987) 1.68
Gene structure, expression pattern, and biological activity of mouse killer cell activating receptor-associated protein (KARAP)/DAP-12. J Biol Chem (1998) 1.68
Characterization of cDNAs encoding human leukosialin and localization of the leukosialin gene to chromosome 16. Proc Natl Acad Sci U S A (1989) 1.68
cAMP-dependent binding of a trans-acting factor to the thyroglobulin promoter. Biochem Biophys Res Commun (1989) 1.67
The gene encoding L1, a neural adhesion molecule of the immunoglobulin family, is located on the X chromosome in mouse and man. Genomics (1990) 1.67
The deltaccr5 mutation conferring protection against HIV-1 in Caucasian populations has a single and recent origin in Northeastern Europe. Hum Mol Genet (1998) 1.67
Human type VII collagen: cDNA cloning and chromosomal mapping of the gene. Proc Natl Acad Sci U S A (1991) 1.66
The putative oncogene Spi-1: murine chromosomal localization and transcriptional activation in murine acute erythroleukemias. Oncogene (1989) 1.65
Molecular characterization of the mouse beta 3-adrenergic receptor: relationship with the atypical receptor of adipocytes. EMBO J (1991) 1.65
Presence of nonfunctional thyrotropin receptor variant transcripts in retroocular and other tissues. J Clin Endocrinol Metab (1994) 1.65
Tyrosine sulfation is required for agonist recognition by glycoprotein hormone receptors. EMBO J (2002) 1.64
Cloning of two novel ABC transporters mapping on human chromosome 9. Genomics (1994) 1.63
The second extracellular loop of CCR5 is the major determinant of ligand specificity. J Biol Chem (1997) 1.62
The inducible cytotoxic T-lymphocyte-associated gene transcript CTLA-1 sequence and gene localization to mouse chromosome 14. Nature (1986) 1.61
A novel X gene with a widely transcribed Y-linked homologue escapes X-inactivation in mouse and human. Hum Mol Genet (1994) 1.60
Chromosome 15 anomalies and the Prader-Willi syndrome: cytogenetic analysis. Hum Genet (1984) 1.58
The orphan receptor cDNA RDC7 encodes an A1 adenosine receptor. EMBO J (1991) 1.57
Cloning, sequencing and expression of the human thyrotropin (TSH) receptor: evidence for binding of autoantibodies. Biochem Biophys Res Commun (1989) 1.57
Structural anomalies of the X chromosome and inactivation center. Hum Genet (1981) 1.57
Modeling of the three-dimensional structure of proteins with the typical leucine-rich repeats. Structure (1995) 1.55
Failure of membrane targeting causes the functional defect of two mutant sodium iodide symporters. J Clin Endocrinol Metab (2000) 1.54
Isolation of a YAC clone covering a cluster of nine S100 genes on human chromosome 1q21: rationale for a new nomenclature of the S100 calcium-binding protein family. Genomics (1995) 1.54
An unusually long poly(purine)-poly(pyrimidine) sequence is located upstream from the human thyroglobulin gene. Nucleic Acids Res (1985) 1.53
A germline mutation of the thyrotropin receptor gene associated with thyrotoxicosis and mitral valve prolapse in a Chinese family. J Clin Endocrinol Metab (1999) 1.51
DNA fingerprinting in domestic animals using four different minisatellite probes. Cytogenet Cell Genet (1988) 1.50
Nucleotide sequence of the gene for human transition protein 1 and its chromosomal localization on chromosome 2. Genomics (1990) 1.49
Cloning of the cDNA encoding human tissue inhibitor of metalloproteinases-3 (TIMP-3) and mapping of the TIMP3 gene to chromosome 22. Genomics (1994) 1.44
Resistance to thyrotropin (TSH) in three families is not associated with mutations in the TSH receptor or TSH. J Clin Endocrinol Metab (1997) 1.44
Identification and characterization of a novel siglec, siglec-7, expressed by human natural killer cells and monocytes. J Biol Chem (1999) 1.44
Triiodothyronine stimulates specifically growth hormone mRNA in rat pituitary tumor cells. Proc Natl Acad Sci U S A (1977) 1.43
Cloning and characterization of human type 2 and type 3 inositol 1,4,5-trisphosphate receptors. Receptors Channels (1994) 1.43
Barx1, a new mouse homeodomain transcription factor expressed in cranio-facial ectomesenchyme and the stomach. Mech Dev (1995) 1.42
Control of thyroglobulin synthesis and secretion (second of two parts). N Engl J Med (1979) 1.41
Brief report: congenital hyperthyroidism caused by a mutation in the thyrotropin-receptor gene. N Engl J Med (1995) 1.41
Isolation of 37 single-copy DNA probes from human chromosome 6 and physical mapping of 11 probes by in situ hybridization. Genomics (1991) 1.40
The mouse neuronal cell surface protein F3: a phosphatidylinositol-anchored member of the immunoglobulin superfamily related to chicken contactin. J Cell Biol (1989) 1.40
Assessment of vascular aging and atherosclerosis in hypertensive subjects: second derivative of photoplethysmogram versus pulse wave velocity. Am J Hypertens (2000) 1.39
Manic-depression locus on X chromosome. Lancet (1991) 1.38
Genetic immunization against the human thyrotropin receptor causes thyroiditis and allows production of monoclonal antibodies recognizing the native receptor. J Immunol (1998) 1.38
The TXP motif in the second transmembrane helix of CCR5. A structural determinant of chemokine-induced activation. J Biol Chem (2001) 1.37
Localization of the human NCAM gene to band q23 of chromosome 11: the third gene coding for a cell interaction molecule mapped to the distal portion of the long arm of chromosome 11. J Cell Biol (1986) 1.37
The structural gene coding for myelin-associated proteolipid protein is mutated in jimpy mice. Nature (1986) 1.36
Prader-Willi syndrome and chromosome 15. A clinical discussion of 20 cases. Hum Genet (1983) 1.36
Multiple charged and aromatic residues in CCR5 amino-terminal domain are involved in high affinity binding of both chemokines and HIV-1 Env protein. J Biol Chem (1999) 1.36
Extracellular cysteines of CCR5 are required for chemokine binding, but dispensable for HIV-1 coreceptor activity. J Biol Chem (1999) 1.34
Characterization of genes encoding translation initiation factor eIF-2gamma in mouse and human: sex chromosome localization, escape from X-inactivation and evolution. Hum Mol Genet (1998) 1.34
Presence and absence of follicle-stimulating hormone receptor mutations provide some insights into spontaneous ovarian hyperstimulation syndrome physiopathology. J Clin Endocrinol Metab (2005) 1.33
Zinedin, SG2NA, and striatin are calmodulin-binding, WD repeat proteins principally expressed in the brain. J Biol Chem (2000) 1.33
Translational control of protein synthesis: a simulation study. Biochim Biophys Acta (1971) 1.32
Genetic immunization of outbred mice with thyrotropin receptor cDNA provides a model of Graves' disease. J Clin Invest (2000) 1.31
Six S100 genes are clustered on human chromosome 1q21: identification of two genes coding for the two previously unreported calcium-binding proteins S100D and S100E. Proc Natl Acad Sci U S A (1993) 1.30