Published in Biotechnology (N Y) on December 01, 1990
Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis. Proc Natl Acad Sci U S A (2007) 15.88
Chemistry and biochemistry of 13C hyperpolarized magnetic resonance using dynamic nuclear polarization. Chem Soc Rev (2013) 1.41
Hyperpolarized (13)C spectroscopy and an NMR-compatible bioreactor system for the investigation of real-time cellular metabolism. Magn Reson Med (2010) 1.18
Bonded Cumomer Analysis of Human Melanoma Metabolism Monitored by 13C NMR Spectroscopy of Perfused Tumor Cells. J Biol Chem (2015) 0.81
Metabolic response of prostate cancer to nicotinamide phophoribosyltransferase inhibition in a hyperpolarized MR/PET compatible bioreactor. Prostate (2015) 0.79
(13)C MRS and LC-MS Flux Analysis of Tumor Intermediary Metabolism. Front Oncol (2016) 0.78
Analysis of CHO-K1 cell growth in a fixed bed bioreactor using magnetic resonance spectroscopy and imaging. Cytotechnology (1999) 0.78
Effect of oxygen concentration on viability and metabolism in a fluidized-bed bioartificial liver using ³¹P and ¹³C NMR spectroscopy. Tissue Eng Part C Methods (2012) 0.76
Comparison of pour and surface plate methods for determination of bacterial counts. Can J Microbiol (1967) 4.48
Factors affecting rate of methane formation from acetic acid by enriched methanogenic cultures. Can J Microbiol (1976) 2.84
Characterization of a strain of Methanospirillum hungatti. Can J Microbiol (1976) 2.16
Competition for mixed substrates by microbial populations. Biotechnol Bioeng (1977) 1.98
Enzymatic catalysis and dynamics in low-water environments. Proc Natl Acad Sci U S A (1992) 1.66
Torsades de pointes associated with high dose levomethadyl acetate (ORLAAM). J Addict Dis (2001) 1.65
Crystal structure of chemically synthesized [N33A] stromal cell-derived factor 1alpha, a potent ligand for the HIV-1 "fusin" coreceptor. Proc Natl Acad Sci U S A (1998) 1.58
A kinetic analysis of hybridoma growth and metabolism in batch and continuous suspension culture: effect of nutrient concentration, dilution rate, and pH. Biotechnol Bioeng (1988) 1.52
Pressure and Temperature Effects on Growth and Methane Production of the Extreme Thermophile Methanococcus jannaschii. Appl Environ Microbiol (1988) 1.51
The appearance of rapidly flowing blood on magnetic resonance images. AJR Am J Roentgenol (1984) 1.46
Improvement of spray gun method of estimating bacterial populations on surfaces. Can J Microbiol (1965) 1.44
Interactions of lysozyme in concentrated electrolyte solutions from dynamic light-scattering measurements. Biophys J (1997) 1.39
Protein-protein and protein-salt interactions in aqueous protein solutions containing concentrated electrolytes. Biotechnol Bioeng (1998) 1.37
By-product inhibition effects on ethanolic fermentation by Saccharomyces cerevisiae. Biotechnol Bioeng (1983) 1.37
Examination of primary metabolic pathways in a murine hybridoma with carbon-13 nuclear magnetic resonance spectroscopy. Biotechnol Bioeng (1994) 1.37
Conformational properties of the complexes formed by proteins and sodium dodecyl sulfate. Biochemistry (1976) 1.29
The functional role of lipids in hydrocarbon assimilation. Biotechnol Bioeng (1974) 1.26
Effect of cobra venom-induced inhibition of complement activity on allograft and xenograft rejection reactions. Transplantation (1967) 1.25
Solvent dielectric effects on protein dynamics. Proc Natl Acad Sci U S A (1992) 1.23
Quantitation of bleeding symptoms in children with von Willebrand disease: use of a standardized pediatric bleeding questionnaire. J Thromb Haemost (2010) 1.21
Protein-protein interactions in concentrated electrolyte solutions. Biotechnol Bioeng (2002) 1.18
Protein adsorption at the oil/water interface: characterization of adsorption kinetics by dynamic interfacial tension measurements. Biophys Chem (1999) 1.15
Effects of hyperbaric pressure on a deep-sea archaebacterium in stainless steel and glass-lined vessels. Appl Environ Microbiol (1991) 1.11
Cadmium removal by a new strain of Pseudomonas aeruginosa in aerobic culture. Appl Environ Microbiol (1997) 1.09
Enzymatic oxidation of cholesterol aggregates in supercritical carbon dioxide. Science (1988) 1.09
Recombinant protein expression in high cell density fed-batch cultures of Escherichia coli. Biotechnology (N Y) (1992) 1.08
Long-range acoustic detection and localization of blue whale calls in the northeast Pacific Ocean. J Acoust Soc Am (1998) 1.03
Defined media optimization for growth of recombinant Escherichia coli X90. Biotechnol Bioeng (1993) 1.02
Pressure stabilization of proteins from extreme thermophiles. Appl Environ Microbiol (1994) 1.02
High-pressure-temperature bioreactor for studying pressure-temperature relationships in bacterial growth and productivity. Biotechnol Bioeng (1988) 1.01
Capillary electrophoresis of DNA in uncross-linked polymer solutions. J Chromatogr A (1993) 1.01
Cloud-point temperatures for lysozyme in electrolyte solutions: effect of salt type, salt concentration and pH. Biophys Chem (2001) 1.00
Inhibitory effect of zinc ions on platelet aggregation and serotonin release reaction. Life Sci (1975) 1.00
Humoral factors in canine renal allograft rejection. Lancet (1968) 0.99
Optimizing the salt-induced activation of enzymes in organic solvents: effects of lyophilization time and water content. Biotechnol Bioeng (1999) 0.99
Feed component inhibition in ethanolic fermentation by Saccharomyces cerevisiae. Biotechnol Bioeng (1984) 0.98
Effects of severe global ischemia on N-acetylaspartate and other metabolites in the rat brain. Magn Reson Med (1997) 0.98
Evidence for two platelet populations in xenograft rejection. Surg Forum (1966) 0.97
The effect of stasis on a microvascular anastomosis. Microsurgery (1983) 0.97
Effects of dissolved oxygen concentration on hybridoma growth and metabolism in continuous culture. J Cell Physiol (1987) 0.97
Normal range of bleeding scores for the ISTH-BAT: adult and pediatric data from the merging project. Haemophilia (2014) 0.97
Studies on the bacterial flora of vacuum-packaged fresh beef. Can J Microbiol (1972) 0.96
Covalent immobilization of protein monolayers for biosensor applications. Biosens Bioelectron (1994) 0.96
Testing for diffusion limitations in salt-activated enzyme catalysts operating in organic solvents. Biotechnol Bioeng (1998) 0.95
Regulation of interferon-stimulated genes in peripheral blood leukocytes in pregnant and bred, nonpregnant dairy cows. J Dairy Sci (2007) 0.94
A kinetic analysis of hybridoma growth and metabolism in batch and continuous suspension culture: effect of nutrient concentration, dilution rate, and pH. Reprinted from Biotechnology and Bioengineering, Vol. 32, Pp 947-965 (1988). Biotechnol Bioeng (2000) 0.94
Four-directional-development thin-layer chromatography of lipids using trimethyl borate. J Lipid Res (1971) 0.92
Effect of lactobacilli and carbon dioxide on the growth of Microbacterium thermosphactum on fresh beef. Can J Microbiol (1975) 0.92
Continuous culture of Methanococcus jannaschii, an extremely thermophilic methanogen. Biotechnol Bioeng (1994) 0.92
Multinuclear NMR study of enzyme hydration in an organic solvent. Biotechnol Bioeng (1998) 0.92
Hydrophobic forces between protein molecules in aqueous solutions of concentrated electrolyte. Biophys Chem (2002) 0.91
Aerobic sulfide production and cadmium precipitation by Escherichia coli expressing the Treponema denticola cysteine desulfhydrase gene. Appl Microbiol Biotechnol (2001) 0.91
Pressure effects on the composition and thermal behavior of lipids from the deep-sea thermophile Methanococcus jannaschii. J Bacteriol (1995) 0.91
Cholesterol aggregation and interaction with cholesterol oxidase in supercritical carbon dioxide. Proc Natl Acad Sci U S A (1988) 0.91
Effect of ferrocyanide on growth and citric acid production by Aspergillus niger. Can J Microbiol (1966) 0.90
Quantitative in vivo nuclear magnetic resonance studies of hybridoma metabolism. Biotechnol Bioeng (1994) 0.89
Mapping of lactate and N-acetyl-L-aspartate predicts infarction during acute focal ischemia: in vivo 1H magnetic resonance spectroscopy in rats. Neurosurgery (1996) 0.89
Molecular cloning of extremely thermostable esterase gene from hyperthermophilic archaeon Pyrococcus furiosus in Escherichia coli. Biotechnol Bioeng (1998) 0.89
Combinatorial biocatalysis: a natural approach to drug discovery. Trends Biotechnol (1998) 0.89
Engineering considerations for the application of extremophiles in biotechnology. Crit Rev Biotechnol (1991) 0.89
High-pressure, high-temperature bioreactor for comparing effects of hyperbaric and hydrostatic pressure on bacterial growth. Appl Environ Microbiol (1992) 0.89
Cell retention-chemostat studies of hybridoma cells-analysis of hybridoma growth and metabolism in continuous suspension culture in serum-free medium. Biotechnol Bioeng (1993) 0.88
Intrinsic effects of solvent polarity on enzymic activation energies. Biotechnol Bioeng (2000) 0.88
Towards more active biocatalysts in organic media: increasing the activity of salt-activated enzymes. Biotechnol Bioeng (2001) 0.88
A transient entanglement coupling mechanism for DNA separation by capillary electrophoresis in ultradilute polymer solutions. Electrophoresis (1994) 0.87
Effector mechanisms in renal graft rejection. Surgery (1967) 0.87
The transient responses of hybridoma cells to nutrient additions in continuous culture: II. Glutamine pulse and step changes. Biotechnol Bioeng (1989) 0.87
Transient responses of hybridoma cells to nutrient additions in continuous culture: I. Glucose pulse and step changes. Biotechnol Bioeng (1989) 0.87
Metabolic engineering of an aerobic sulfate reduction pathway and its application to precipitation of cadmium on the cell surface. Appl Environ Microbiol (2000) 0.87
Studies on the mechanism of canine renal allograft rejection. Transplant Proc (1969) 0.87
Eeconomic evaluation of alternative ethanol fermentation processes. Biotechnol Bioeng (1984) 0.87
Effect of azone and propylene glycol on penetration of trifluorothymidine through skin and efficacy of different topical formulations against cutaneous herpes simplex virus infections in guinea pigs. Antimicrob Agents Chemother (1984) 0.86
Construction of a tethered poly(ethylene glycol) surface gradient for studies of cell adhesion kinetics. Langmuir (2005) 0.86
Phase behavior of aqueous solutions containing dipolar proteins from second-order perturbation theory. J Chem Phys (2004) 0.86
Early dialysis in the treatment of acute renal failure. Surg Gynecol Obstet (1966) 0.86
Microscopy of DNA in dilute polymer solutions. Biotechnol Prog (1998) 0.85
Engineering hydrogen sulfide production and cadmium removal by expression of the thiosulfate reductase gene (phsABC) from Salmonella enterica serovar typhimurium in Escherichia coli. Appl Environ Microbiol (2000) 0.85
Kinetics of the enzymatic hydrolysis of cellulose. Biotechnol Bioeng (1984) 0.85
In vitro and in vivo stability of diluted recombinant factor VIII for continuous infusion use in haemophilia A. Haemophilia (2009) 0.84
Pressure-enhanced activity and stability of a hyperthermophilic protease from a deep-sea methanogen. Appl Environ Microbiol (1997) 0.84
In situ extractive fermentation of acetone and butanol. Biotechnol Bioeng (1988) 0.84
Active-site titration of serine proteases in organic solvents. Biotechnol Bioeng (1996) 0.84
Detection of Streptococcus mutans by PCR amplification of spaP gene. J Med Microbiol (1994) 0.84
A theory for the electrophoretic separation of DNA in polymer solutions. Electrophoresis (1998) 0.83
Peptide interfacial adsorption is kinetically limited by the thermodynamic stability of self association. Proc Natl Acad Sci U S A (2000) 0.83
Using isotopomer path tracing to quantify metabolic fluxes in pathway models containing reversible reactions. Biotechnol Bioeng (2001) 0.83
Transient responses of hybridoma cells in continuous culture to step changes in amino acid and vitamin concentrations. Biotechnol Bioeng (1994) 0.83
Pressure effects on enzyme activity and stability at high temperatures. Adv Protein Chem (1996) 0.83
Some characteristics of protein precipitation by salts. Biotechnol Bioeng (1992) 0.83
Structural and catalytic properties of enzymes in reverse micelles. Enzyme Microb Technol (1993) 0.82
A kinetic analysis of hybridoma growth and metabolism in continuous suspension culture on serum-free medium. Biotechnol Bioeng (1991) 0.82
Mechanisms of protein solubilization in reverse micelles. Biotechnol Bioeng (1992) 0.82
Interaction between oppositely charged micelles or globular proteins. Phys Rev E Stat Phys Plasmas Fluids Relat Interdiscip Topics (2000) 0.82