Published in Neuron on June 01, 1992
Nitric oxide and peroxynitrite in health and disease. Physiol Rev (2007) 15.49
Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures. Proc Natl Acad Sci U S A (1995) 4.84
Nitric oxide-induced mitochondrial fission is regulated by dynamin-related GTPases in neurons. EMBO J (2006) 4.43
Balance between synaptic versus extrasynaptic NMDA receptor activity influences inclusions and neurotoxicity of mutant huntingtin. Nat Med (2009) 2.66
Endogenous generation of reactive oxidants and electrophiles and their reactions with DNA and protein. J Clin Invest (2003) 2.41
Chemokines and activated macrophages in HIV gp120-induced neuronal apoptosis. Proc Natl Acad Sci U S A (1999) 2.40
Neurotoxicity associated with dual actions of homocysteine at the N-methyl-D-aspartate receptor. Proc Natl Acad Sci U S A (1997) 2.32
Hydrogen sulfide as a gasotransmitter. J Neurochem (2010) 2.30
Redox modulation of L-type calcium channels in ferret ventricular myocytes. Dual mechanism regulation by nitric oxide and S-nitrosothiols. J Gen Physiol (1996) 2.24
A new form of cerebellar long-term potentiation is postsynaptic and depends on nitric oxide but not cAMP. Proc Natl Acad Sci U S A (2002) 1.85
Isogenic human iPSC Parkinson's model shows nitrosative stress-induced dysfunction in MEF2-PGC1α transcription. Cell (2013) 1.61
Reactive astrocytes as therapeutic targets for CNS disorders. Neurotherapeutics (2010) 1.60
Aberrant protein s-nitrosylation in neurodegenerative diseases. Neuron (2013) 1.55
Transnitrosylation of XIAP regulates caspase-dependent neuronal cell death. Mol Cell (2010) 1.44
Stimulation by nitric oxide of an NAD linkage to glyceraldehyde-3-phosphate dehydrogenase. Proc Natl Acad Sci U S A (1993) 1.37
Mitochondria, oxidative stress, and temporal lobe epilepsy. Epilepsy Res (2009) 1.37
Dominant-interfering forms of MEF2 generated by caspase cleavage contribute to NMDA-induced neuronal apoptosis. Proc Natl Acad Sci U S A (2002) 1.35
Free radicals as mediators of neuronal injury. Cell Mol Neurobiol (1998) 1.28
S-Nitrosylation of DRP1 does not affect enzymatic activity and is not specific to Alzheimer's disease. J Alzheimers Dis (2010) 1.26
Hypoxia enhances S-nitrosylation-mediated NMDA receptor inhibition via a thiol oxygen sensor motif. Neuron (2007) 1.26
Altered synaptic plasticity and memory formation in nitric oxide synthase inhibitor-treated rats. Proc Natl Acad Sci U S A (1993) 1.25
NO signaling and S-nitrosylation regulate PTEN inhibition in neurodegeneration. Mol Neurodegener (2010) 1.23
TGF-{beta}1 activates two distinct type I receptors in neurons: implications for neuronal NF-{kappa}B signaling. J Cell Biol (2005) 1.19
Redox regulation of mitochondrial fission, protein misfolding, synaptic damage, and neuronal cell death: potential implications for Alzheimer's and Parkinson's diseases. Apoptosis (2010) 1.16
Redox reactions induced by nitrosative stress mediate protein misfolding and mitochondrial dysfunction in neurodegenerative diseases. Mol Neurobiol (2010) 1.13
On-off system for PI3-kinase-Akt signaling through S-nitrosylation of phosphatase with sequence homology to tensin (PTEN). Proc Natl Acad Sci U S A (2011) 1.10
A Golgi fragmentation pathway in neurodegeneration. Neurobiol Dis (2007) 1.09
Differential regulation of BACE1 expression by oxidative and nitrosative signals. Mol Neurodegener (2011) 1.06
Myocyte enhancer factor 2C as a neurogenic and antiapoptotic transcription factor in murine embryonic stem cells. J Neurosci (2008) 1.06
Structure mechanism insights and the role of nitric oxide donation guide the development of oxadiazole-2-oxides as therapeutic agents against schistosomiasis. J Med Chem (2009) 1.05
NMDA receptors and metaplasticity: mechanisms and possible roles in neuropsychiatric disorders. Neurosci Biobehav Rev (2012) 1.03
Caspase-mediated apoptosis in neuronal excitotoxicity triggered by nitric oxide. Mol Med (1997) 1.03
Oxidative damage to the c-fos gene and reduction of its transcription after focal cerebral ischemia. J Neurochem (1999) 1.01
Nitric oxide. Ann Rheum Dis (1996) 0.99
Role of nitric oxide in learning and memory and in monoamine metabolism in the rat brain. Br J Pharmacol (1995) 0.98
Nitric oxide: foe or friend to the injured brain? Proc Natl Acad Sci U S A (1993) 0.96
Nitric oxide reversibly inhibits the epidermal growth factor receptor tyrosine kinase. Biochem J (1997) 0.96
Specificity in S-nitrosylation: a short-range mechanism for NO signaling? Antioxid Redox Signal (2013) 0.96
Nitric oxide increases persistent sodium current in rat hippocampal neurons. J Physiol (1999) 0.93
Oxidized glutathione mediates cation channel activation in calf vascular endothelial cells during oxidant stress. J Physiol (1996) 0.90
Nitric oxide-related species inhibit evoked neurotransmission but enhance spontaneous miniature synaptic currents in central neuronal cultures. Proc Natl Acad Sci U S A (1996) 0.89
Hyperbaric hyperoxia and normobaric reoxygenation increase excitability and activate oxygen-induced potentiation in CA1 hippocampal neurons. J Appl Physiol (1985) (2010) 0.89
Protein S-Nitrosylation as a Therapeutic Target for Neurodegenerative Diseases. Trends Pharmacol Sci (2015) 0.89
Intracellular cysteine 346 is essentially involved in regulating Panx1 channel activity. J Biol Chem (2010) 0.89
A recombinant vaccinia virus encoding inducible nitric oxide synthase is attenuated in vivo. J Virol (1996) 0.88
Concentration dynamics of nitric oxide in rat hippocampal subregions evoked by stimulation of the NMDA glutamate receptor. Proc Natl Acad Sci U S A (2005) 0.87
Increased striatal dopamine efflux in vivo following inhibition of cerebral nitric oxide synthase by the novel monosodium salt of 7-nitro indazole. Br J Pharmacol (1995) 0.87
Nitric oxide-mediated modulation of the endothelin-1 signalling pathway in the human cardiovascular system. Br J Pharmacol (2001) 0.87
Regulation of nerve growth factor release by nitric oxide through cyclic GMP pathway in cortical glial cells. Mol Pharmacol (1999) 0.86
Molecular Mechanisms of Neurodegenerative Diseases Induced by Human Retroviruses: A Review. Am J Infect Dis (2009) 0.86
HIV-1 protein Tat produces biphasic changes in NMDA-evoked increases in intracellular Ca2+ concentration via activation of Src kinase and nitric oxide signaling pathways. J Neurochem (2014) 0.86
cGMP-mediated effects on the physiology of bovine and human retinal Müller (glial) cells. J Physiol (1996) 0.86
Neurovascular protection by ischaemic tolerance: role of nitric oxide. J Physiol (2011) 0.84
Nitric oxide inhibits nociceptive transmission by differentially regulating glutamate and glycine release to spinal dorsal horn neurons. J Biol Chem (2011) 0.84
Parallel evolution of nitric oxide signaling: diversity of synthesis and memory pathways. Front Biosci (Landmark Ed) (2011) 0.83
The role of s-nitrosylation and s-glutathionylation of protein disulphide isomerase in protein misfolding and neurodegeneration. Int J Cell Biol (2013) 0.83
Nitrosylation of ISG15 prevents the disulfide bond-mediated dimerization of ISG15 and contributes to effective ISGylation. J Biol Chem (2008) 0.83
Modulation of calcium-activated non-selective cation channel activity by nitric oxide in rat brown adipose tissue. J Physiol (1995) 0.82
Photolytically released nitric oxide produces a delayed but persistent suppression of LTP in area CA1 of the rat hippocampal slice. J Physiol (1999) 0.81
Transnitrosylation from DJ-1 to PTEN attenuates neuronal cell death in parkinson's disease models. J Neurosci (2014) 0.80
Novel activation of non-selective cationic channels by dinitrosyl iron-thiosulfate in PC12 cells. J Physiol (2000) 0.80
Differential regulation of the slow and rapid components of guinea-pig cardiac delayed rectifier K+ channels by hypoxia. J Physiol (2003) 0.80
Modulation of ionotropic glutamate receptors and Acid-sensing ion channels by nitric oxide. Front Physiol (2012) 0.80
Effect of isosorbiddinitrate on exogenously expressed slowly activating K+ channels and endogenous K+ channels in Xenopus oocytes. J Physiol (1996) 0.80
Cell density plays a critical role in ex vivo expansion of T cells for adoptive immunotherapy. J Biomed Biotechnol (2010) 0.80
The relation of different-scale membrane processes under nitric oxide influence. J Biol Phys (2005) 0.79
Integrating cytosolic phospholipase A₂ with oxidative/nitrosative signaling pathways in neurons: a novel therapeutic strategy for AD. Mol Neurobiol (2012) 0.79
A peptide derived from acetylcholinesterase induces neuronal cell death: characterisation of possible mechanisms. Exp Brain Res (2003) 0.78
Immunohistochemical study on the expression of calcium binding proteins (calbindin-D28k, calretinin, and parvalbumin) in the cerebellum of the nNOS knock-out(-/-) mice. Anat Cell Biol (2010) 0.78
Nitrosative Stress, Hypernitrosylation, and Autoimmune Responses to Nitrosylated Proteins: New Pathways in Neuroprogressive Disorders Including Depression and Chronic Fatigue Syndrome. Mol Neurobiol (2016) 0.77
Effect of L-arginine/nitric oxide pathway on MPP(+)-induced cell injury in the striatum of rats. Br J Pharmacol (1994) 0.77
Reactive Oxygen Species: Physiological and Physiopathological Effects on Synaptic Plasticity. J Exp Neurosci (2016) 0.77
Role of superoxide dismutase in ischemic brain injury: a study using SOD-1 transgenic mice. Cell Mol Neurobiol (1998) 0.77
Application of a novel technique for clinical evaluation of nitric oxide-induced free radical reactions in ICU patients. Cell Mol Neurobiol (1999) 0.77
Lack of interaction between nitric oxide and the redox modulatory site of the NMDA receptor. Br J Pharmacol (1999) 0.76
ER stress upregulated PGE₂/IFNγ-induced IL-6 expression and down-regulated iNOS expression in glial cells. Sci Rep (2013) 0.76
Expression of NADPH-diaphorase and nitric oxide synthase in lumbosacral motoneurons after knee joint immobilisation in the guinea pig. J Anat (1997) 0.76
Mesencephalic neuron death induced by congeners of nitrogen monoxide is prevented by the lazaroid U-83836E. Exp Brain Res (1997) 0.76
Neuronal nitric oxide synthase in the neural pathways of the urinary bladder. J Anat (1999) 0.76
Role of sulfiredoxin as a peroxiredoxin-2 denitrosylase in human iPSC-derived dopaminergic neurons. Proc Natl Acad Sci U S A (2016) 0.75
Effects of L-arginine pre-treatment in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's diseases in Balb/c mice. Iran J Neurol (2015) 0.75
Nitrosative Stress in the Nervous System: Guidelines for Designing Experimental Strategies to Study Protein S-Nitrosylation. Neurochem Res (2015) 0.75
Redox pioneer: Professor Stuart A. Lipton. Antioxid Redox Signal (2013) 0.75
Glutathione and thioredoxin type 1 cooperatively denitrosate HepG2 cells-derived cytosolic S-nitrosoproteins. Org Biomol Chem (2013) 0.75
S-nitrosylation of fatty acid synthase regulates its activity through dimerization. J Lipid Res (2016) 0.75
Gelatinase activity imaged by activatable cell-penetrating peptides in cell-based and in vivo models of stroke. J Cereb Blood Flow Metab (2015) 0.75
Nitric oxide donor-mediated inhibition of phosphorylation shows that light-mediated degradation of photosystem II D1 protein and phosphorylation are not tightly linked. Planta (2009) 0.75
On the role of nitric oxide as a cellular messenger in brain. Mol Cell Biochem (1996) 0.75
Influence of drugs acting on nitric oxide-dependent pathways on ethanol tolerance in rats. Psychopharmacology (Berl) (2003) 0.75
Neurological and neuropsychological consequences of electrical and lightning shock: review and theories of causation. Neural Regen Res (2017) 0.75
Endogenous nitric oxide inhibits spinal NMDA receptor activity pain hypersensitivity induced by nerve injury. Neuropharmacology (2017) 0.75
Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009. Cell Death Differ (2008) 10.45
Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012. Cell Death Differ (2011) 9.44
A redox-based mechanism for the neuroprotective and neurodestructive effects of nitric oxide and related nitroso-compounds. Nature (1993) 8.29
Pathways to neuronal injury and apoptosis in HIV-associated dementia. Nature (2001) 5.60
Apoptosis and necrosis: two distinct events induced, respectively, by mild and intense insults with N-methyl-D-aspartate or nitric oxide/superoxide in cortical cell cultures. Proc Natl Acad Sci U S A (1995) 4.84
Erythropoietin-mediated neuroprotection involves cross-talk between Jak2 and NF-kappaB signalling cascades. Nature (2001) 4.35
Tissue plasminogen activator (tPA) increases neuronal damage after focal cerebral ischemia in wild-type and tPA-deficient mice. Nat Med (1998) 4.09
Glutamate-induced neuronal death: a succession of necrosis or apoptosis depending on mitochondrial function. Neuron (1995) 4.07
Characterization of two classes of small molecule inhibitors of Arp2/3 complex. Nature (2009) 3.83
(S)NO signals: translocation, regulation, and a consensus motif. Neuron (1997) 3.67
Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes. Cell Death Differ (2009) 3.44
HIV-1 coat protein neurotoxicity prevented by calcium channel antagonists. Science (1990) 3.41
Characteristics of sudden death in hemodialysis patients. Kidney Int (2006) 2.80
Increased NMDA current and spine density in mice lacking the NMDA receptor subunit NR3A. Nature (1998) 2.59
HIV-1 infection and AIDS: consequences for the central nervous system. Cell Death Differ (2005) 2.54
hMEF2C gene encodes skeletal muscle- and brain-specific transcription factors. Mol Cell Biol (1993) 2.41
Chemokines and activated macrophages in HIV gp120-induced neuronal apoptosis. Proc Natl Acad Sci U S A (1999) 2.40
Open-channel block of N-methyl-D-aspartate (NMDA) responses by memantine: therapeutic advantage against NMDA receptor-mediated neurotoxicity. J Neurosci (1992) 2.25
Molecular basis of NMDA receptor-coupled ion channel modulation by S-nitrosylation. Nat Neurosci (2000) 2.24
Activation of the Keap1/Nrf2 pathway for neuroprotection by electrophilic [correction of electrophillic] phase II inducers. Proc Natl Acad Sci U S A (2006) 2.15
Regulation of nitric oxide synthase activity in human immunodeficiency virus type 1 (HIV-1)-infected monocytes: implications for HIV-associated neurological disease. J Exp Med (1995) 2.11
MEF2C, a MADS/MEF2-family transcription factor expressed in a laminar distribution in cerebral cortex. Proc Natl Acad Sci U S A (1993) 2.07
New York City syndromic surveillance systems. MMWR Morb Mortal Wkly Rep (2004) 1.91
Benchmark data and power calculations for evaluating disease outbreak detection methods. MMWR Morb Mortal Wkly Rep (2004) 1.86
The neuropathogenesis of HIV-1 infection. J Leukoc Biol (1994) 1.83
Molecular cloning and characterization of human endothelial nitric oxide synthase. FEBS Lett (1992) 1.79
Mitochondrial fission is an upstream and required event for bax foci formation in response to nitric oxide in cortical neurons. Cell Death Differ (2006) 1.77
Assembly with the NR1 subunit is required for surface expression of NR3A-containing NMDA receptors. J Neurosci (2001) 1.75
Molecular basis of glutamate toxicity in retinal ganglion cells. Vision Res (1997) 1.74
Synergistic effects of HIV coat protein and NMDA receptor-mediated neurotoxicity. Neuron (1991) 1.73
The Henry Ford Hospital Headache Disability Inventory (HDI). Neurology (1994) 1.72
Developmental and regional expression pattern of a novel NMDA receptor-like subunit (NMDAR-L) in the rodent brain. J Neurosci (1995) 1.70
Validity of spirometric testing in a general practice population of patients with chronic obstructive pulmonary disease (COPD). Thorax (2003) 1.70
Transverse-momentum and pseudorapidity distributions of charged hadrons in pp collisions at square root of s = 7 TeV. Phys Rev Lett (2010) 1.67
Mechanism of memantine block of NMDA-activated channels in rat retinal ganglion cells: uncompetitive antagonism. J Physiol (1997) 1.66
Selective modulation of NMDA responses by reduction and oxidation. Neuron (1989) 1.64
Elevated glutamate levels in the vitreous body of humans and monkeys with glaucoma. Arch Ophthalmol (1996) 1.64
Increased mRNA expression of a laminin-binding protein in human colon carcinoma: complete sequence of a full-length cDNA encoding the protein. Proc Natl Acad Sci U S A (1988) 1.62
Identification and mechanism of action of two histidine residues underlying high-affinity Zn2+ inhibition of the NMDA receptor. Neuron (1999) 1.62
New perspectives on glaucoma. JAMA (1999) 1.60
Neurotransmitter regulation of neuronal outgrowth, plasticity and survival. Trends Neurosci (1989) 1.59
Study of the mass and spin-parity of the Higgs boson candidate via its decays to Z boson pairs. Phys Rev Lett (2013) 1.56
The LEC rat has a deletion in the copper transporting ATPase gene homologous to the Wilson disease gene. Nat Genet (1994) 1.52
Antiapoptotic role of the p38 mitogen-activated protein kinase-myocyte enhancer factor 2 transcription factor pathway during neuronal differentiation. Proc Natl Acad Sci U S A (2000) 1.52
Mitochondrial and extramitochondrial apoptotic signaling pathways in cerebrocortical neurons. Proc Natl Acad Sci U S A (2000) 1.51
Selective alterations in gene expression for NMDA receptor subunits in prefrontal cortex of schizophrenics. J Neurosci (1996) 1.50
Identification of two cysteine residues that are required for redox modulation of the NMDA subtype of glutamate receptor. Neuron (1994) 1.50
HIV-1 coreceptors CCR5 and CXCR4 both mediate neuronal cell death but CCR5 paradoxically can also contribute to protection. Cell Death Differ (2006) 1.50
Electrical and adaptive properties of rod photoreceptors in Bufo marinus. II. Effects of cyclic nucleotides and prostaglandins. J Gen Physiol (1977) 1.50
A novel gene, AF1q, fused to MLL in t(1;11) (q21;q23), is specifically expressed in leukemic and immature hematopoietic cells. Blood (1995) 1.48
Superior rectal artery injury following lumbar disc surgery. Case report. J Neurosurg (2001) 1.43
Mice deficient in Mac-1 (CD11b/CD18) are less susceptible to cerebral ischemia/reperfusion injury. Stroke (1999) 1.42
Immunocytochemical demonstration of vasopressin binding in rat kidney. J Histochem Cytochem (1990) 1.39
A mutation in the human ryanodine receptor gene associated with central core disease. Nat Genet (1993) 1.37
Modulation of endothelial cell proliferation, adhesion, and motility by recombinant heparin-binding domain and synthetic peptides from the type I repeats of thrombospondin. J Cell Biochem (1993) 1.37
NMDA receptors: from genes to channels. Trends Pharmacol Sci (1996) 1.36
Intra-arterial infusion of anticancer drugs: theoretic aspects of drug delivery and review of responses. Cancer Treat Rep (1980) 1.35
FOXM1 is a transcriptional target of ERalpha and has a critical role in breast cancer endocrine sensitivity and resistance. Oncogene (2010) 1.34
Role of p38 mitogen-activated protein kinase in axotomy-induced apoptosis of rat retinal ganglion cells. J Neurosci (2000) 1.34
Cloning of a gamma-aminobutyric acid type C receptor subunit in rat retina with a methionine residue critical for picrotoxinin channel block. Proc Natl Acad Sci U S A (1995) 1.31
Monoclonal antibody to Thy-1 enhances regeneration of processes by rat retinal ganglion cells in culture. Science (1984) 1.30
In-vitro clonogenic assay for predicting response of ovarian cancer to chemotherapy. Lancet (1980) 1.30
Psychosocial interest, medical interviews, and the recognition of depression. Arch Fam Med (1994) 1.28
A phase I/II trial of nimodipine for HIV-related neurologic complications. Neurology (1998) 1.27
Redox modulation by S-nitrosylation contributes to protein misfolding, mitochondrial dynamics, and neuronal synaptic damage in neurodegenerative diseases. Cell Death Differ (2011) 1.25
Microstructure of fragile metallic glasses inferred from ultrasound-accelerated crystallization in Pd-based metallic glasses. Phys Rev Lett (2005) 1.24
Attenuation of NMDA receptor activity and neurotoxicity by nitroxyl anion, NO-. Neuron (1999) 1.24
Measurement of the electron charge asymmetry in inclusive W production in pp collisions at sqrt[s]=7 TeV. Phys Rev Lett (2012) 1.23
Lipid peroxidation: a possible role in the induction and progression of chronic periodontitis. J Periodontal Res (2005) 1.21
An NMDA receptor signaling complex with protein phosphatase 2A. J Neurosci (2001) 1.21
N-methyl-D-aspartate receptors are critical for mediating the effects of glutamate on intracellular calcium concentration and immediate early gene expression in cultured hippocampal neurons. Neuroscience (1995) 1.20
Cystic fibrosis transmembrane conductance regulator mutations that disrupt nucleotide binding. J Clin Invest (1994) 1.20
Search for new physics in the multijet and missing transverse momentum final state in proton-proton collisions at √s = 7 TeV. Phys Rev Lett (2012) 1.19
Molecular stages of rapid and uniform neuralization of human embryonic stem cells. Cell Death Differ (2009) 1.19
Azimuthal anisotropy of charged particles at high transverse momenta in Pb-Pb collisions at sqrt[s(NN)] = 2.76 TeV. Phys Rev Lett (2012) 1.19
Chronic low-dose glutamate is toxic to retinal ganglion cells. Toxicity blocked by memantine. Invest Ophthalmol Vis Sci (1996) 1.15
Multiple GABA receptor subtypes mediate inhibition of calcium influx at rat retinal bipolar cell terminals. J Neurosci (1995) 1.15
Three pairs of cysteine residues mediate both redox and zn2+ modulation of the nmda receptor. J Neurosci (2001) 1.14
Cytoskeletal breakdown and apoptosis elicited by NO donors in cerebellar granule cells require NMDA receptor activation. J Neurochem (1996) 1.13
Intrinsic anion channel activity of the recombinant first nucleotide binding fold domain of the cystic fibrosis transmembrane regulator protein. Proc Natl Acad Sci U S A (1992) 1.12
Structure and function of GABA(C) receptors: a comparison of native versus recombinant receptors. Trends Pharmacol Sci (2001) 1.12
Role of caspases in N-methyl-D-aspartate-induced apoptosis in cerebrocortical neurons. J Neurochem (1998) 1.11
Talon cusp in primary dentition. Oral Surg Oral Med Oral Pathol (1986) 1.11
Electrical and adaptive properties of rod photoreceptors in Bufo marinus. I. Effects of altered extracellular Ca2+ levels. J Gen Physiol (1977) 1.11
Search for a W' or techni-ρ decaying into WZ in pp Collisions at sqrt[s] = 7 TeV. Phys Rev Lett (2012) 1.10
Neuroprotective effects of tanshinones in transient focal cerebral ischemia in mice. Phytomedicine (2003) 1.10
Esophageal foreign body mimicking esophageal atresia. Indian Pediatr (2005) 1.09
Search for new physics with same-sign isolated dilepton events with jets and missing transverse energy. Phys Rev Lett (2012) 1.09