Published in J Exp Med on May 01, 1960
Studies on the mode of action of excess of vitamin A. 1. Effect of excess of vitamin A on the metabolism and composition of embryonic chick-limb cartilage grown in organ culture. Biochem J (1961) 4.85
STUDIES ON LYSOSOMES. III. THE EFFECTS OF STREPTOLYSINS O AND S ON THE RELEASE OF ACID HYDROLASES FROM A GRANULAR FRACTION OF RABBIT LIVER. J Exp Med (1963) 3.15
Comparison of the effects of papain and vitamin A on cartilage. II. The effects on organ cultures of embryonic skeletal tissue. J Exp Med (1960) 3.08
Studies on lysosomes. II. The effect of cortisone on the release of acid hydrolases from a large granule fraction of rabbit liver induced by an excess of vitamin A. J Clin Invest (1963) 2.89
Studies on the mode of action of excess of vitamin A. 2. A possible role of intracellular proteases in the degradation of cartilage matrix. Biochem J (1961) 2.56
Studies on the mode of action of excess of vitamin A. 5. The effect of vitamin A on the stability of the erythrocyte membrane. Biochem J (1962) 2.41
The influence of hydrocortisone on the action of excess vitamin A on limb bone rudiments in culture. J Exp Med (1961) 2.35
Leukocytic proteases and the immunologic release of lysosomal enzymes. Am J Pathol (1972) 2.26
Biochemical and Immunological Effects of Listeria monocytogenes Hemolysin. Infect Immun (1970) 2.07
Immunopathologic studies in relapsing polychondritis. J Clin Invest (1973) 1.98
Studies on the mode of action of excess of vitamin A. 4. The specificity of the effect on embryonic chick-limb cartilage in culture and on isolated rat-liver lysosomes. Biochem J (1962) 1.87
Cartilage resorption in the tibial epiphyseal plate of growing rats. J Cell Biol (1967) 1.75
Proteases involved in cartilage matrix degradation in osteoarthritis. Biochim Biophys Acta (2011) 1.73
Effects of vitamin A and glucocorticoids upon inflammation and collagen synthesis. Ann Surg (1973) 1.47
The glycosaminoglycans of human plasma. J Clin Invest (1969) 1.39
Laryngotracheitis virus in chickens. A model for study of acute nonfatal desquamating rhinitis. J Exp Med (1967) 1.31
Steroids, lyosomes and systemic lupus erythematosus. Bull N Y Acad Med (1962) 1.26
Cartilage matrix depletion by rheumatoid synovial cells in tissue culture. J Exp Med (1967) 1.22
Relapsing polychondritis. Report of two necropsied cases with histochemical investigation of the cartilage lesion Am J Pathol (1963) 1.17
The action of cathepsin D in human articular cartilage on proteoglycans. J Clin Invest (1973) 1.12
Role of biological membranes in some skeletal reactions. Ann Rheum Dis (1969) 1.01
Cell-mediated immunity to cartilage proteoglycan in relapsing polychondritis. Clin Exp Immunol (1974) 0.99
Immunofluorescent studies of human articular cartilage. Ann Rheum Dis (1966) 0.99
Prevention by cortisone of the changes in cartilage induced by an excess of vitamin A in rabbits. Am J Pathol (1963) 0.99
THE SUSCEPTIBILITY OF CHICK EMBRYO SKIN ORGAN CULTURES TO INFLUENZA VIRUS FOLLOWING EXCESS VITAMIN A. J Exp Med (1964) 0.97
CHANGES IN CONNECTIVE TISSUE AND INTESTINE CAUSED BY VITAMIN A IN AMPHIBIA, AND THEIR ACCELERATION BY HYDROCORTISONE. J Exp Med (1961) 0.93
THE EFFECTS OF PAPAIN, VITAMIN A, AND CORTISONE ON CARTILAGE MATRIX IN VIVO. Biophys J (1964) 0.91
Studies on the pathogenesis of acute inflammation. IV. The failure of papain and hyaluronida se to modify leukgcytic sticking within rabbit ear chambers injured by heat. Am J Pathol (1962) 0.82
Transforming growth factor beta stimulates urokinase-type plasminogen activator and DNA synthesis, but not prostaglandin E2 production, in human synovial fibroblasts. Proc Natl Acad Sci U S A (1991) 0.78
Virus-induced lysosomal enzyme dissolution of nasal turbinate cartilage. Am J Pathol (1977) 0.77
Aetiological factors in the collagen diseases. Increased vascular permeability, chondrolysis and cortisone. Proc R Soc Med (1962) 0.77
The effect of complement-sufficient antiserum against pig erythrocytes on pig articular tissues in organ culture. Agents Actions (1976) 0.75
Reversible collapse of rabbit ears after intravenous papain, and prevention of recovery by cortisone. J Exp Med (1956) 7.43
Chondromucoprotein: new extraction method and alkaline degradation. J Biol Chem (1958) 4.77
Separation of chondroitin sulfate from cartilage. J Biol Chem (1950) 4.71
Comparison of the effects of papain and vitamin A on cartilage. II. The effects on organ cultures of embryonic skeletal tissue. J Exp Med (1960) 3.08
Radioautographic visualization of sulfur-35 disposition in the articular cartilage and bone of suckling rats following injection of labeled sodium sulfate. J Exp Med (1951) 3.04
The metachromatic staining reaction. J Histochem Cytochem (1955) 2.37
Influence of excess vitamin A on the sulphate metabolism of bone rudiments grown in vitro. J Physiol (1956) 2.28
The release of chondroitin sulfate from rabbit cartilage following the intravenous injection of crude papain. Arch Biochem Biophys (1958) 2.10
The removal of cartilage matrix, in vivo, by papain; identification of crystalline papain protease as the cause of the phenomenon. J Exp Med (1958) 2.07
The effects of a vitaminosis and hypervitaminosis A upon the incisor teeth and incisal alveolar bone of rats. J Physiol (1949) 1.72
Turbidity produced by hexamminecobaltic chloride in serum of rabbits injected intravenously with papain. Proc Soc Exp Biol Med (1960) 1.72
Application of alcian blue as a histochemical method. Lab Invest (1958) 1.54
The biological action of thyroxine on embryonic bones grown in tissue culture. J Physiol (1955) 1.54
The metabolism of mucopolysaccharides in animals: the effect of cortisone and hydrocortisone on rat skin. Endocrinology (1957) 1.41
The removal of cartilage matrix in vivo by papain; prevention of recovery with cortisone, hydrocortisone and prednisoione by a direct action on cartilage. Am J Pathol (1959) 1.29
DELAYED HYPERSENSITIVITY IN VITRO. I. THE SPECIFICITY OF INHIBITION OF CELL MIGRATION BY ANTIGENS. J Immunol (1964) 14.77
The physiological disturbances produced by endotoxins. Annu Rev Physiol (1954) 10.40
Studies on the generalized Shwartzman reaction: I. General observations concerning the phenomenon. J Exp Med (1952) 9.61
Studies on the mechanism of the Shwartzman phenomenon. J Exp Med (1949) 8.07
Reversible collapse of rabbit ears after intravenous papain, and prevention of recovery by cortisone. J Exp Med (1956) 7.43
Studies on the generalized Shwartzman reaction. IV. Prevention of the local and generalized Shwartzman reactions with heparin. J Exp Med (1953) 6.41
Studies on lysosomes. I. The effects of endotoxin, endotoxin tolerance, and cortisone on the release of acid hydrolases from a granular fraction of rabbit liver. J Exp Med (1962) 4.57
The role of epinephrine in the reactions produced by the endotoxins of gram-negative bacteria. I. Hemorrhagic necrosis produced by epinephrine in the skin of endotoxin-treated rabbits. J Exp Med (1956) 4.42
POSSIBLE ROLE OF LEUCOCYTE GRANULES IN THE SHWARTZMAN AND ARTHUS REACTIONS. Proc Soc Exp Biol Med (1964) 4.02
MOTION PICTURE STUDY OF THE TOXIC ACTION OF STREPTOLYSINS ON LEUCOCYTES. J Exp Med (1963) 3.68
The lethal effect of endotoxins on the chick embryo. J Exp Med (1956) 3.62
Generalized Shwartzman reaction. V. Intravenous injection of collidal iron or carbon on response of rabbits to meningococcal toxin. Proc Soc Exp Biol Med (1953) 3.58
Release of lysosomal protease by ultraviolet irradiation and inhibition by hydrocortisone. Exp Cell Res (1961) 3.56
Studies on the generalized Shwartzman reaction. III. Lesions of the myocardium and coronary arteries accompanying the reaction in rabbits prepared by infection with group A streptococci. J Exp Med (1953) 3.47
Cold-precipitation by heparin of a protein in rabbit and human plasma. Proc Soc Exp Biol Med (1955) 3.29
Localization of colloidal substances in vascular endothelium: a mechanism of tissue damage. I. Factors causing the pathologic deposition of colloidal carbon. Am J Pathol (1959) 3.28
STUDIES ON LYSOSOMES. III. THE EFFECTS OF STREPTOLYSINS O AND S ON THE RELEASE OF ACID HYDROLASES FROM A GRANULAR FRACTION OF RABBIT LIVER. J Exp Med (1963) 3.15
Hemorrhagic skin lesions produced by intradermal meningococcus toxin in rabbits following treatment with ACTH or cortisone. Proc Soc Exp Biol Med (1950) 3.13
Comparison of the effects of papain and vitamin A on cartilage. II. The effects on organ cultures of embryonic skeletal tissue. J Exp Med (1960) 3.08
Inhibition of the Shwartzman phenomenon by local application of bromobenzene and other solvents. Proc Soc Exp Biol Med (1948) 2.96
Studies on lysosomes. II. The effect of cortisone on the release of acid hydrolases from a large granule fraction of rabbit liver induced by an excess of vitamin A. J Clin Invest (1963) 2.89
Morphologic changes in rabbits following the intravenous administration of meningococcal toxin. II. Two appropriately spaced injections; the rôle of fibrinoid in the generalized Shwartzman reaction. Am J Pathol (1955) 2.68
Acute disseminated encephalomyelitis following immunization with homologous brain extracts; studies on the role of a circulating antibody in the production of the condition in dogs. J Exp Med (1950) 2.60
Morphologic changes in rabbits following the intravenous administration of meningococcal toxin. I. The effects produced in young and in mature animals by a single injection. Am J Pathol (1955) 2.58
IN VITRO STUDIES ON HOMOGRAFT SENSITIVITY. Nature (1965) 2.50
Pathogenesis of experimental shock. IV. Studies on lysosomes in normal and tolerant animals subjected to lethal trauma and endotoxemia. J Exp Med (1962) 2.39
Studies on the generalized Shwartzman reaction. VII. The role of fibrinogen in the deposition of fibrinoid after combined injections of endotoxin and synthetic acidic polymer. J Exp Med (1955) 2.39
The pathologic effects of intravenously administered soluble antigen-antibody complexes. I. Passive serum sickness in mice. J Exp Med (1960) 2.36
The influence of hydrocortisone on the action of excess vitamin A on limb bone rudiments in culture. J Exp Med (1961) 2.35
DELAYED HYPERSENSITIVITY IN VITRO. 3. THE SPECIFICITY OF HAPTEN-PROTEIN CONJUGATES IN THE INHIBITION OF CELL MIGRATION. J Immunol (1964) 2.32
Influence of age upon response to meningococcal endotoxin in rabbits. Proc Soc Exp Biol Med (1955) 2.09
The removal of cartilage matrix, in vivo, by papain; identification of crystalline papain protease as the cause of the phenomenon. J Exp Med (1958) 2.07
LABILIZATION AND STABILIZATION OF LYSOSOMES. Fed Proc (1965) 2.05
Bilateral cortical necrosis of kidneys in cortisone-treated rabbits following injection of bacterial toxins. Proc Soc Exp Biol Med (1951) 1.98
THE EFFECTS OF CORTICOSTEROIDS UPON CONNECTIVE TISSUE AND LYSOSOMES. Recent Prog Horm Res (1964) 1.98
Effect of cortisone on response to endotoxin in mature rabbits. Proc Soc Exp Biol Med (1955) 1.94
Morphologic changes in rabbits following the intravenous administration of meningococcal toxin. III. The effects produced by endotoxin in association with certain high molecular weight acidic polymers. Am J Pathol (1955) 1.94
The relationship between the vascular manifestations of shock produced by endotoxin, trauma, and hemorrhage. I. Certain similarities between the reactions in normal and endotoxin-tolerant rats. J Exp Med (1957) 1.90
Increased fixation of sulfur-35 by cartilage in vitro following depletion of the matrix by intravenous papain. J Exp Med (1960) 1.87
Trophoblast in the circulating blood during pregnancy. Am J Obstet Gynecol (1959) 1.85
STUDIES ON PULMONARY SECRETIONS. I. THE OVER-ALL CHEMICAL COMPOSITION OF PULMONARY SECRETIONS FROM PATIENTS WITH CYSTIC FIBROSIS, BRONCHIECTASIS, AND LARYNGECTOMY. Am Rev Respir Dis (1963) 1.81
Studies on the generalized Shwartzman reaction. VIII. The appearance, by electron microscopy, of intravascular fibrinoid in the glomerular capillaries during the reaction. J Exp Med (1958) 1.75
RELATIONSHIP OF FOX RABIES TO CAVES. Public Health Rep (1965) 1.75
Turbidity produced by hexamminecobaltic chloride in serum of rabbits injected intravenously with papain. Proc Soc Exp Biol Med (1960) 1.72
STUDIES ON LYSOSOMES. V. THE EFFECTS OF STREPTOLYSINS AND OTHER HEMOLYTIC AGENTS ON ISOLATED LEUCOCYTE GRANULES. J Cell Biol (1964) 1.71
The demonstration of type specific streptococcal antibody by a hemagglutination technique employing tannic acid. J Clin Invest (1953) 1.66
STUDIES ON LYSOSOMES. VII. ACUTE AND CHRONIC ARTHRITIS PRODUCED BY INTRA-ARTICULAR INJECTIONS OF STREPTOLYSIN S IN RABBITS. Am J Pathol (1965) 1.63
Cortisone and infection. Ann N Y Acad Sci (1953) 1.62
Studies on the mechanisms involved in the production of abortion by endotoxin. J Immunol (1960) 1.61
Blood clearance of P32-labeled vesicular stomatitis and Newcastle disease viruses by the reticuloendothelial system in mice. J Immunol (1960) 1.59
LYMPHATIC TRANSPORT OF BETA-GLUCURONIDASE DURING HAEMORRHAGIC SHOCK. Nature (1964) 1.57
Effect of cortisone administration upon nucleic acid composition of rabbit liver. Proc Soc Exp Biol Med (1951) 1.57
INDUCTION OF UNRESPONSIVENESS AND IMMUNITY IN NEWBORN AND ADULT MICE WITH PNEUMOCOCCAL POLYSACCHARIDE. J Immunol (1963) 1.55
The effect of hydrocortisone on the response of fetal rat skin in culture to ultraviolet irradiation. J Exp Med (1962) 1.55
The effects of cortisone on bacterial infection; group A hemolytic streptococcal infection in rabbits. J Lab Clin Med (1952) 1.53
The removal of cartilage matrix by papain. Factors affecting the distribution of crystalline papain in vivo. J Exp Med (1960) 1.50
CIRCULATING AUTOANTIBODIES AND HUMAN DISEASE. WITH A NOTE ON PRIMARY ATYPICAL PNEUMONIA. N Engl J Med (1964) 1.48
STUDIES ON LYSOSOMES. IV. SOLUBILIZATION OF ENZYMES DURING MITOCHONDRIAL SWELLING AND DISRUPTION OF LYSOSOMES BY STREPTOLYSIN S AND OTHER HEMOLYTIC AGENTS. J Cell Biol (1964) 1.45
THE IN VITRO DESENSITIZATION OF SENSITIVE CELLS BY TRYPSIN. J Exp Med (1964) 1.43
Mechanisms in the production of tissue damage and shock by endotoxins. Trans Assoc Am Physicians (1957) 1.36
The specificity of skin homograft rejection in man. Ann N Y Acad Sci (1960) 1.36
LYSOSOMES. Blood (1964) 1.30
Immunohistochemical demonstration of the reticuloendothelial clearance of circulating fibrin aggregates. J Exp Med (1962) 1.30
LYSOSOMES, AUTOIMMUNE PHENOMENA, AND DISEASES OF CONNECTIVE TISSUE. Lancet (1964) 1.29
The removal of cartilage matrix in vivo by papain; prevention of recovery with cortisone, hydrocortisone and prednisoione by a direct action on cartilage. Am J Pathol (1959) 1.29
Steroids, lyosomes and systemic lupus erythematosus. Bull N Y Acad Med (1962) 1.26
Impairment of 'enzyme-binding capacity' of serum in rheumatoid disease. Proc R Soc Med (1962) 1.25
Production of acute glomerulonephritis in mice with soluble antigen-antibody complexes prepared from homologous antibody. Proc Soc Exp Biol Med (1961) 1.25
ISOLATION AND PROPERTIES OF HUMAN LEUKOCYTE LYSOSOMES IN VITRO. Proc Soc Exp Biol Med (1965) 1.21
Skin homograft sensitivity cross reactions in man. Ann N Y Acad Sci (1962) 1.20
ACID PHOSPHATASE-RICH GRANULES IN HUMAN LYMPHOCYTES INDUCED BY PHYTOHEMAGGLUTININ. Science (1965) 1.19
Physiologic and pathologic alterations produced by the endotoxins of gram-negative bacteria. AMA Arch Intern Med (1958) 1.18
Action of venom phosphodiesterase on deoxyribooligonucleotides carrying a monoesterified phosphate on carbon 3'. J Biol Chem (1960) 1.17
The nature of anaemia in rheumatoid arthritis. V. Red Cell survival measured by radioactive chromium. Ann Rheum Dis (1961) 1.15
Cross-reactions to skin homografts in man. J Clin Invest (1962) 1.15
Human pulmonary secretions in health and disease. Ann N Y Acad Sci (1963) 1.14
STUDIES OF LYSOSOMES. VI. THE EFFECT OF NEUTRAL STEROIDS AND BILE ACIDS ON LYSOSOMES IN VITRO. Biochem Pharmacol (1965) 1.14
Alterations in connective tissue and intestine produced by hypervitaminosis A in Xenopus laevis. Nature (1961) 1.12
Acute hypervitaminosis A in guinea pigs, I, Effects on acid hydroalases. Proc Soc Exp Biol Med (1963) 1.10
Cortisone, ACTH and infection. Bull N Y Acad Med (1955) 1.07