Published in Mol Carcinog on January 01, 1992
Protein kinase Cdelta targets mitochondria, alters mitochondrial membrane potential, and induces apoptosis in normal and neoplastic keratinocytes when overexpressed by an adenoviral vector. Mol Cell Biol (1999) 1.51
Regulation of epidermal differentiation by a Distal-less homeodomain gene. J Cell Biol (1996) 1.49
Modulation of keratinocyte growth factor and its receptor in reepithelializing human skin. J Exp Med (1995) 1.29
A mitosis block links active cell cycle with human epidermal differentiation and results in endoreplication. PLoS One (2010) 0.95
The mysterious human epidermal cell cycle, or an oncogene-induced differentiation checkpoint. Cell Cycle (2012) 0.92
Galectin-7 Regulates Keratinocyte Proliferation and Differentiation through JNK-miR-203-p63 Signaling. J Invest Dermatol (2016) 0.77
Clasp2 ensures mitotic fidelity and prevents differentiation of epidermal keratinocytes. J Cell Sci (2017) 0.75
p63 is a p53 homologue required for limb and epidermal morphogenesis. Nature (1999) 13.21
Calcium regulation of growth and differentiation of mouse epidermal cells in culture. Cell (1980) 8.10
Molecular and cellular biology of intermediate filaments. Annu Rev Biochem (1988) 5.48
Complete amino acid sequence of a mouse epidermal keratin subunit and implications for the structure of intermediate filaments. Nature (1983) 3.51
Expression of murine epidermal differentiation markers is tightly regulated by restricted extracellular calcium concentrations in vitro. J Cell Biol (1989) 3.21
The molecular biology of intermediate filaments. Cell (1985) 3.17
Deregulated expression of c-Myc depletes epidermal stem cells. Nat Genet (2001) 3.00
Multiple defects and perinatal death in mice deficient in follistatin. Nature (1995) 2.96
Transcription of structural and intervening sequences in the ovalbumin gene and identification of potential ovalbumin mRNA precursors. Cell (1978) 2.87
Characterization of bullous pemphigoid antigen: a unique basement membrane protein of stratified squamous epithelia. Cell (1981) 2.72
Functional analysis of activins during mammalian development. Nature (1995) 2.71
Transplacental effects of 3'-azido-2',3'-dideoxythymidine (AZT): tumorigenicity in mice and genotoxicity in mice and monkeys. J Natl Cancer Inst (1997) 2.61
A survey of transformation markers in differentiating epidermal cell lines in culture. Cancer Res (1980) 2.53
Structure and expression of a chicken gene coding for U1 RNA. Cell (1981) 2.51
c-fos is required for malignant progression of skin tumors. Cell (1995) 2.39
Lessons from loricrin-deficient mice: compensatory mechanisms maintaining skin barrier function in the absence of a major cornified envelope protein. J Cell Biol (2000) 2.22
Isolation and utilization of epidermal keratinocytes for oncogene research. Methods Enzymol (1995) 2.10
Synthetic peptides corresponding to keratin subunits elicit highly specific antibodies. J Biol Chem (1984) 1.96
Mouse skin cells resistant to terminal differentiation associated with initiation of carcinogenesis. Nature (1981) 1.96
FVB/N mice: an inbred strain sensitive to the chemical induction of squamous cell carcinomas in the skin. Carcinogenesis (1993) 1.95
Altered differentiation of mouse epidermal cells treated with retinyl acetate in vitro. Exp Cell Res (1974) 1.94
Characterization of human loricrin. Structure and function of a new class of epidermal cell envelope proteins. J Biol Chem (1991) 1.91
Down-regulation of p63 is required for epidermal UV-B-induced apoptosis. Cancer Res (2000) 1.88
Reduced skin tumor development in cyclin D1-deficient mice highlights the oncogenic ras pathway in vivo. Genes Dev (1998) 1.88
An activated Harvey ras oncogene produces benign tumours on mouse epidermal tissue. Nature (1986) 1.86
Tumour promoter induces anchorage independence irreversibly. Nature (1979) 1.83
Structure of a gene for the human epidermal 67-kDa keratin. Proc Natl Acad Sci U S A (1985) 1.82
Targeted expression of a dominant-negative FGF receptor mutant in the epidermis of transgenic mice reveals a role of FGF in keratinocyte organization and differentiation. EMBO J (1993) 1.78
Definition of the 5' and 3' ends of transcripts of the ovalbumin gene. Cell (1980) 1.77
Mutations in the rod domains of keratins 1 and 10 in epidermolytic hyperkeratosis. Science (1992) 1.73
Platinum-DNA adducts in leukocyte DNA correlate with disease response in ovarian cancer patients receiving platinum-based chemotherapy. Proc Natl Acad Sci U S A (1987) 1.71
Inhibition of skin development by overexpression of transforming growth factor beta 1 in the epidermis of transgenic mice. Proc Natl Acad Sci U S A (1993) 1.68
Reconstitution of hair follicle development in vivo: determination of follicle formation, hair growth, and hair quality by dermal cells. J Invest Dermatol (1993) 1.66
A pilot project in molecular cancer epidemiology: determination of benzo[a]pyrene--DNA adducts in animal and human tissues by immunoassays. Carcinogenesis (1982) 1.66
Malignant conversion of mouse skin tumours is increased by tumour initiators and unaffected by tumour promoters. Nature (1983) 1.65
Keratin gene expression in mouse epidermis and cultured epidermal cells. Proc Natl Acad Sci U S A (1983) 1.64
Genetically null mice reveal a central role for epidermal growth factor receptor in the differentiation of the hair follicle and normal hair development. Am J Pathol (1997) 1.62
Regulated expression of differentiation-associated keratins in cultured epidermal cells detected by monospecific antibodies to unique peptides of mouse epidermal keratins. Differentiation (1987) 1.62
Retinoic acid induces transforming growth factor-beta 2 in cultured keratinocytes and mouse epidermis. Cell Regul (1989) 1.61
Effect of estrogen on gene expression in the chick oviduct. Regulation of the ovomucoid gene. Biochemistry (1978) 1.59
Optimized conditions for the growth of human epidermal cells in culture. J Invest Dermatol (1980) 1.57
An inducible mouse model for epidermolysis bullosa simplex: implications for gene therapy. J Cell Biol (2001) 1.55
Coordinate changes in gene expression which mark the spinous to granular cell transition in epidermis are regulated by protein kinase C. J Cell Biol (1993) 1.54
Phorbol esters stimulate DNA synthesis and ornithine decarboxylase activity in mouse epidermal cell cultures. Nature (1976) 1.54
Differential keratin gene expression in developing, differentiating, preneoplastic, and neoplastic mouse mammary epithelium. Cell Growth Differ (1990) 1.53
The complete cDNA and deduced amino acid sequence of a type II mouse epidermal keratin of 60,000 Da: analysis of sequence differences between type I and type II keratins. Proc Natl Acad Sci U S A (1984) 1.52
Protein kinase Cdelta targets mitochondria, alters mitochondrial membrane potential, and induces apoptosis in normal and neoplastic keratinocytes when overexpressed by an adenoviral vector. Mol Cell Biol (1999) 1.51
Quantitation of benzo(a)pyrene-deoxyguanosine adducts by radioimmunoassay. Cancer Res (1980) 1.49
Involvement of protein kinase C delta (PKCdelta) in phorbol ester-induced apoptosis in LNCaP prostate cancer cells. Lack of proteolytic cleavage of PKCdelta. J Biol Chem (2000) 1.49
Expression of a dominant-negative type II transforming growth factor beta (TGF-beta) receptor in the epidermis of transgenic mice blocks TGF-beta-mediated growth inhibition. Proc Natl Acad Sci U S A (1997) 1.47
Delayed wound healing in keratin 6a knockout mice. Mol Cell Biol (2000) 1.44
Development of murine epidermal cell lines which contain an activated rasHa oncogene and form papillomas in skin grafts on athymic nude mouse hosts. Cancer Res (1988) 1.44
Bryostatin 1, an activator of protein kinase C, inhibits tumor promotion by phorbol esters in SENCAR mouse skin. Carcinogenesis (1987) 1.44
Divergent responses in epidermal basal cells exposed to the tumor promoter 12-O-tetradecanoylphorbol-13-acetate. Cancer Res (1982) 1.44
Altered growth and differentiation of cultured mouse epidermal cells infected with oncogenic retrovirus: contrasting effects of viruses and chemicals. Cancer Res (1983) 1.43
Amino acid sequences of mouse and human epidermal type II keratins of Mr 67,000 provide a systematic basis for the structural and functional diversity of the end domains of keratin intermediate filament subunits. J Biol Chem (1985) 1.43
Development of gene-switch transgenic mice that inducibly express transforming growth factor beta1 in the epidermis. Proc Natl Acad Sci U S A (1999) 1.42
Loss of expression of transforming growth factor beta in skin and skin tumors is associated with hyperproliferation and a high risk for malignant conversion. Proc Natl Acad Sci U S A (1993) 1.40
In vivo regulation of murine hair growth: insights from grafting defined cell populations onto nude mice. J Invest Dermatol (1993) 1.39
Functions of the POU domain genes Skn-1a/i and Tst-1/Oct-6/SCIP in epidermal differentiation. Genes Dev (1997) 1.39
The measurement of cisplatin-DNA adduct levels in testicular cancer patients. Carcinogenesis (1988) 1.38
Organization of a type I keratin gene. Evidence for evolution of intermediate filaments from a common ancestral gene. J Biol Chem (1985) 1.38
Targeted deletion of the TGF-beta 1 gene causes rapid progression to squamous cell carcinoma. Genes Dev (1994) 1.37
Expression of an oncogenic rasHa gene in murine keratinocytes induces tyrosine phosphorylation and reduced activity of protein kinase C delta. J Biol Chem (1993) 1.37
NAD(P)H:quinone oxidoreductase 1 deficiency increases susceptibility to benzo(a)pyrene-induced mouse skin carcinogenesis. Cancer Res (2000) 1.37
Identification of potential ovomucoid mRNA precursors in chick oviduct nuclei. Nature (1979) 1.36
Induction of papillomas with a high probability of conversion to malignancy. Carcinogenesis (1985) 1.36
Evidence that deoxyribonucleic acid sequences flanking the ovalbumin gene are not transcribed. Biochemistry (1980) 1.36
A role for TGFbeta1 in langerhans cell biology. Further characterization of the epidermal Langerhans cell defect in TGFbeta1 null mice. J Clin Invest (1997) 1.35
Quantitation of cis-diamminedichloroplatinum II (cisplatin)-DNA-intrastrand adducts in testicular and ovarian cancer patients receiving cisplatin chemotherapy. J Clin Invest (1986) 1.35
Deregulated minichromosomal maintenance protein MCM7 contributes to oncogene driven tumorigenesis. Oncogene (2006) 1.35
Induction of epidermal hyperplasia, hyperkeratosis, and papillomas in transgenic mice by a targeted v-Ha-ras oncogene. Mol Carcinog (1993) 1.35
Activation of the epidermal growth factor receptor signal transduction pathway stimulates tyrosine phosphorylation of protein kinase C delta. J Biol Chem (1996) 1.34
p53-mediated transcriptional activity increases in differentiating epidermal keratinocytes in association with decreased p53 protein. Oncogene (1995) 1.34
Antibodies elicited against cis-diamminedichloroplatinum(II)-modified DNA are specific for cis-diamminedichloroplatinum(II)-DNA adducts formed in vivo and in vitro. Proc Natl Acad Sci U S A (1982) 1.33
Discovery of a novel murine keratin 6 (K6) isoform explains the absence of hair and nail defects in mice deficient for K6a and K6b. J Cell Biol (2001) 1.30
Targeted disruption of the epidermal growth factor receptor impairs growth of squamous papillomas expressing the v-ras(Ha) oncogene but does not block in vitro keratinocyte responses to oncogenic ras. Cancer Res (1997) 1.27
p53 and tumor necrosis factor alpha regulate the expression of a mitochondrial chloride channel protein. J Biol Chem (1999) 1.27
Early signals for keratinocyte differentiation: role of Ca2+-mediated inositol lipid metabolism in normal and neoplastic epidermal cells. Carcinogenesis (1988) 1.26
Comparison of two-stage epidermal carcinogenesis initiated by 7,12-dimethylbenz(a)anthracene or N-methyl-N'-nitro-N-nitrosoguanidine in newborn and adult SENCAR and BALB/c mice. Cancer Res (1981) 1.26
Detection of carcinogen-DNA adducts by radiommunoassay. Nature (1977) 1.26
The expression and modulation of IL-1 alpha in murine keratinocytes. J Immunol (1988) 1.25
Specific epidermal protein markers are modulated during calcium-induced terminal differentiation. J Cell Biol (1983) 1.24
TGF alpha and v-fos cooperation in transgenic mouse epidermis induces aberrant keratinocyte differentiation and stable, autonomous papillomas. Oncogene (1995) 1.24
Biosynthetic pathways of filaggrin and loricrin--two major proteins expressed by terminally differentiated epidermal keratinocytes. J Struct Biol (1991) 1.24
Epidermal cell culture. Transplant Proc (1980) 1.24
Characterization of an inducible, epidermal-specific knockout system: differential expression of lacZ in different Cre reporter mouse strains. Genesis (2000) 1.23
Transforming growth factor beta 1 suppresses genomic instability independent of a G1 arrest, p53, and Rb. Cancer Res (1996) 1.23
Subunit structure of the mouse epidermal keratin filament. Biochim Biophys Acta (1979) 1.21
NAD(P)H:quinone oxidoreductase 1 deficiency and increased susceptibility to 7,12-dimethylbenz[a]-anthracene-induced carcinogenesis in mouse skin. J Natl Cancer Inst (2001) 1.21
Measurement of benzo(a)pyrene-DNA adducts by enzyme immunoassays and radioimmunoassay. Cancer Res (1981) 1.20
Genetic deletion of p21WAF1 enhances papilloma formation but not malignant conversion in experimental mouse skin carcinogenesis. Cancer Res (1999) 1.19
Evaluation of platinum-DNA adduct levels relative to known prognostic variables in a cohort of ovarian cancer patients. Cancer Res (1990) 1.19
Quantitative assay for carcinogen altered differentiation in mouse epidermal cells. Carcinogenesis (1980) 1.17
Transcriptional control of high molecular weight keratin gene expression in multistage mouse skin carcinogenesis. Cancer Res (1988) 1.17
Myoepitheliomas in inbred laboratory mice. Vet Pathol (1991) 1.16
Expression of a p53 mutant in the epidermis of transgenic mice accelerates chemical carcinogenesis. Oncogene (1998) 1.16