Published in Cancer Res on March 01, 1981
Langerhans cells facilitate epithelial DNA damage and squamous cell carcinoma. Science (2012) 1.24
Use of biological assay systems to assess the relative carcinogenic hazards of disinfection by-products. Environ Health Perspect (1982) 1.17
Molecular analysis of tumor-promoting CD8+ T cells in two-stage cutaneous chemical carcinogenesis. J Invest Dermatol (2009) 0.95
Functions of the aryl hydrocarbon receptor in the skin. Semin Immunopathol (2013) 0.95
SENCAR mouse skin tumorigenesis model versus other strains and stocks of mice. Environ Health Perspect (1986) 0.86
Differential carcinogenic effects of intraperitoneal initiation with 7,12-dimethylbenz(a)anthracene or urethane and topical promotion with 12-O-tetradecanoylphorbol-13-acetate in skin and internal tissues of female SENCAR and BALB/c mice. Environ Health Perspect (1986) 0.85
An initiator of carcinogenesis selectively and stably inhibits stem cell differentiation: a concept that initiation of carcinogenesis involves multiple phases. Proc Natl Acad Sci U S A (1985) 0.85
Skin-specific expression of a truncated E1a oncoprotein binding to p105-Rb leads to abnormal hair follicle maturation without increased epidermal proliferation. J Cell Biol (1993) 0.84
Loss of the platelet activating factor receptor in mice augments PMA-induced inflammation and cutaneous chemical carcinogenesis. Carcinogenesis (2012) 0.84
Phorbol myristate acetate and catechol as skin cocarcinogens in SENCAR mice. Environ Health Perspect (1986) 0.83
Strain-specific properties and T cells regulate the susceptibility to papilloma induction by Mus musculus papillomavirus 1. PLoS Pathog (2014) 0.82
Pathology of aging female SENCAR mice used as controls in skin two-stage carcinogenesis studies. Environ Health Perspect (1986) 0.79
Immunoprevention of chemical carcinogenesis through early recognition of oncogene mutations. J Immunol (2015) 0.78
Photocarcinogenesis and persistent hyperplasia in UV-irradiated SENCAR mouse skin. Environ Health Perspect (1986) 0.76
Metabolic activation of benzo(a)pyrene in SENCAR and BALB/c mouse embryo cell cultures. Environ Health Perspect (1986) 0.75
In vitro comparisons of SENCAR and BALB/c primary epidermal cells. Environ Health Perspect (1986) 0.75
MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer. Oncogene (2007) 10.79
Calcium regulation of growth and differentiation of mouse epidermal cells in culture. Cell (1980) 8.10
MicroRNA-21 promotes cell transformation by targeting the programmed cell death 4 gene. Oncogene (2008) 4.43
Activation of the mouse cellular Harvey-ras gene in chemically induced benign skin papillomas. Nature (1984) 4.28
Characterization of bullous pemphigoid antigen: a unique basement membrane protein of stratified squamous epithelia. Cell (1981) 2.72
Transplacental effects of 3'-azido-2',3'-dideoxythymidine (AZT): tumorigenicity in mice and genotoxicity in mice and monkeys. J Natl Cancer Inst (1997) 2.61
A survey of transformation markers in differentiating epidermal cell lines in culture. Cancer Res (1980) 2.53
Calcium regulation of cell-cell contact and differentiation of epidermal cells in culture. An ultrastructural study. Exp Cell Res (1983) 2.43
Blocking of tumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells. Proc Natl Acad Sci U S A (1994) 2.43
c-fos is required for malignant progression of skin tumors. Cell (1995) 2.39
The mRNA coding for the secreted protease transin is expressed more abundantly in malignant than in benign tumors. Proc Natl Acad Sci U S A (1986) 2.28
Correlation of anchorage-independent growth with tumorigenicity of chemically transformed mouse epidermal cells. Cancer Res (1978) 2.23
Differentially expressed protein Pdcd4 inhibits tumor promoter-induced neoplastic transformation. Proc Natl Acad Sci U S A (1999) 2.19
Isolation and utilization of epidermal keratinocytes for oncogene research. Methods Enzymol (1995) 2.10
A novel transformation suppressor, Pdcd4, inhibits AP-1 transactivation but not NF-kappaB or ODC transactivation. Oncogene (2001) 2.08
Wnt/beta-catenin signaling induces the expression and activity of betaTrCP ubiquitin ligase receptor. Mol Cell (2000) 2.02
Synthetic peptides corresponding to keratin subunits elicit highly specific antibodies. J Biol Chem (1984) 1.96
Mouse skin cells resistant to terminal differentiation associated with initiation of carcinogenesis. Nature (1981) 1.96
FVB/N mice: an inbred strain sensitive to the chemical induction of squamous cell carcinomas in the skin. Carcinogenesis (1993) 1.95
Studies on the mechanism of skin tumor promotion: evidence for several stages in promotion. Proc Natl Acad Sci U S A (1980) 1.94
Regulation of connexin 43-mediated gap junctional intercellular communication by Ca2+ in mouse epidermal cells is controlled by E-cadherin. J Cell Biol (1991) 1.94
Altered differentiation of mouse epidermal cells treated with retinyl acetate in vitro. Exp Cell Res (1974) 1.94
Reduced skin tumor development in cyclin D1-deficient mice highlights the oncogenic ras pathway in vivo. Genes Dev (1998) 1.88
An activated Harvey ras oncogene produces benign tumours on mouse epidermal tissue. Nature (1986) 1.86
Dissociation of mitogenesis and late-stage promotion of tumor cell phenotype by phorbol esters: mitogen-resistant variants are sensitive to promotion. Proc Natl Acad Sci U S A (1981) 1.84
Tumour promoter induces anchorage independence irreversibly. Nature (1979) 1.83
Targeted expression of a dominant-negative FGF receptor mutant in the epidermis of transgenic mice reveals a role of FGF in keratinocyte organization and differentiation. EMBO J (1993) 1.78
Neonatal cholestasis in alpha-1-antitrypsin deficient children. Clinical, genetic, histological and immunohistochemical findings. Acta Paediatr Scand (1972) 1.77
Primary sclerosing cholangitis: a long-term follow-up study. Scand J Gastroenterol (1987) 1.73
Platinum-DNA adducts in leukocyte DNA correlate with disease response in ovarian cancer patients receiving platinum-based chemotherapy. Proc Natl Acad Sci U S A (1987) 1.71
Reconstitution of hair follicle development in vivo: determination of follicle formation, hair growth, and hair quality by dermal cells. J Invest Dermatol (1993) 1.66
A pilot project in molecular cancer epidemiology: determination of benzo[a]pyrene--DNA adducts in animal and human tissues by immunoassays. Carcinogenesis (1982) 1.66
Epidermal growth factor. Ability of tumor promoter to alter its degradation, receptor affinity and receptor number. J Biol Chem (1980) 1.65
Malignant conversion of mouse skin tumours is increased by tumour initiators and unaffected by tumour promoters. Nature (1983) 1.65
Keratin gene expression in mouse epidermis and cultured epidermal cells. Proc Natl Acad Sci U S A (1983) 1.64
AP1/jun function is differentially induced in promotion-sensitive and resistant JB6 cells. Science (1989) 1.63
Skin tumor-promoting activity of benzoyl peroxide, a widely used free radical-generating compound. Science (1981) 1.63
Genetically null mice reveal a central role for epidermal growth factor receptor in the differentiation of the hair follicle and normal hair development. Am J Pathol (1997) 1.62
Tumor suppressor Pdcd4 inhibits invasion/intravasation and regulates urokinase receptor (u-PAR) gene expression via Sp-transcription factors. Oncogene (2007) 1.62
Regulated expression of differentiation-associated keratins in cultured epidermal cells detected by monospecific antibodies to unique peptides of mouse epidermal keratins. Differentiation (1987) 1.62
Retinoic acid induces transforming growth factor-beta 2 in cultured keratinocytes and mouse epidermis. Cell Regul (1989) 1.61
Molecular cloning of five messenger RNAs differentially expressed in preneoplastic or neoplastic JB6 mouse epidermal cells: one is homologous to human tissue inhibitor of metalloproteinases-3. Cancer Res (1994) 1.57
Optimized conditions for the growth of human epidermal cells in culture. J Invest Dermatol (1980) 1.57
Comparison of the tumor-initiating activity of 7,12-dimethylbenz[a]anthracene and benzo[a]pyrene in female SENCAR and CS-1 mice. Carcinogenesis (1980) 1.55
Coordinate changes in gene expression which mark the spinous to granular cell transition in epidermis are regulated by protein kinase C. J Cell Biol (1993) 1.54
Phorbol esters stimulate DNA synthesis and ornithine decarboxylase activity in mouse epidermal cell cultures. Nature (1976) 1.54
Specific and nonspecific humoral defense factors in the epithelium of normal and inflamed gastric mucosa. Immunohistochemical localization of immunoglobulins, secretory component, lysozyme, and lactoferrin. Gastroenterology (1984) 1.53
Activator protein 1 (AP-1)- and nuclear factor kappaB (NF-kappaB)-dependent transcriptional events in carcinogenesis. Free Radic Biol Med (2000) 1.53
Protein kinase Cdelta targets mitochondria, alters mitochondrial membrane potential, and induces apoptosis in normal and neoplastic keratinocytes when overexpressed by an adenoviral vector. Mol Cell Biol (1999) 1.51
Quantitation of benzo(a)pyrene-deoxyguanosine adducts by radioimmunoassay. Cancer Res (1980) 1.49
Involvement of protein kinase C delta (PKCdelta) in phorbol ester-induced apoptosis in LNCaP prostate cancer cells. Lack of proteolytic cleavage of PKCdelta. J Biol Chem (2000) 1.49
Studies on mechanism of action of anti-tumor-promoting agents: their specificity in two-stage promotion. Proc Natl Acad Sci U S A (1980) 1.47
Evidence that the centrally and peripherally located cells in the murine epidermal proliferative unit are two distinct cell populations. J Invest Dermatol (1985) 1.47
Expression of the metalloproteinase matrilysin in DU-145 cells increases their invasive potential in severe combined immunodeficient mice. Cancer Res (1993) 1.45
Bryostatin 1, an activator of protein kinase C, inhibits tumor promotion by phorbol esters in SENCAR mouse skin. Carcinogenesis (1987) 1.44
Development of murine epidermal cell lines which contain an activated rasHa oncogene and form papillomas in skin grafts on athymic nude mouse hosts. Cancer Res (1988) 1.44
Divergent responses in epidermal basal cells exposed to the tumor promoter 12-O-tetradecanoylphorbol-13-acetate. Cancer Res (1982) 1.44
Altered growth and differentiation of cultured mouse epidermal cells infected with oncogenic retrovirus: contrasting effects of viruses and chemicals. Cancer Res (1983) 1.43
Overview of tumor promotion in animals. Environ Health Perspect (1983) 1.43
TIMP-3 induces cell death by stabilizing TNF-alpha receptors on the surface of human colon carcinoma cells. Cytokine (1997) 1.42
Evidence that a slowly cycling subpopulation of adult murine epidermal cells retains carcinogen. Cancer Res (1986) 1.41
Inhibition of tumor promoter-induced transformation by retinoids that transrepress AP-1 without transactivating retinoic acid response element. Cancer Res (1996) 1.41
Ultraviolet B regulation of transcription factor families: roles of nuclear factor-kappa B (NF-kappaB) and activator protein-1 (AP-1) in UVB-induced skin carcinogenesis. Curr Cancer Drug Targets (2007) 1.41
Loss of expression of transforming growth factor beta in skin and skin tumors is associated with hyperproliferation and a high risk for malignant conversion. Proc Natl Acad Sci U S A (1993) 1.40
[Natural products can be hazardous to health]. Tidsskr Nor Laegeforen (1992) 1.39
In vivo regulation of murine hair growth: insights from grafting defined cell populations onto nude mice. J Invest Dermatol (1993) 1.39
Functions of the POU domain genes Skn-1a/i and Tst-1/Oct-6/SCIP in epidermal differentiation. Genes Dev (1997) 1.39
The measurement of cisplatin-DNA adduct levels in testicular cancer patients. Carcinogenesis (1988) 1.38
Targeted deletion of the TGF-beta 1 gene causes rapid progression to squamous cell carcinoma. Genes Dev (1994) 1.37
Expression of an oncogenic rasHa gene in murine keratinocytes induces tyrosine phosphorylation and reduced activity of protein kinase C delta. J Biol Chem (1993) 1.37
Role of p38 MAP kinases and ERK in mediating ultraviolet-B induced cyclooxygenase-2 gene expression in human keratinocytes. Oncogene (2001) 1.36
Inhibitors of both nuclear factor-kappaB and activator protein-1 activation block the neoplastic transformation response. Cancer Res (1997) 1.36
Induction of papillomas with a high probability of conversion to malignancy. Carcinogenesis (1985) 1.36
Quantitation of cis-diamminedichloroplatinum II (cisplatin)-DNA-intrastrand adducts in testicular and ovarian cancer patients receiving cisplatin chemotherapy. J Clin Invest (1986) 1.35
Activation of the epidermal growth factor receptor signal transduction pathway stimulates tyrosine phosphorylation of protein kinase C delta. J Biol Chem (1996) 1.34
p53-mediated transcriptional activity increases in differentiating epidermal keratinocytes in association with decreased p53 protein. Oncogene (1995) 1.34
Down regulation of specific binding of [20-3H]phorbol 12,13-dibutyrate and phorbol ester-induced differentiation of human promyelocytic leukemia cells. Proc Natl Acad Sci U S A (1981) 1.34
Antibodies elicited against cis-diamminedichloroplatinum(II)-modified DNA are specific for cis-diamminedichloroplatinum(II)-DNA adducts formed in vivo and in vitro. Proc Natl Acad Sci U S A (1982) 1.33
An infrequent point mutation of the p53 gene in human nasopharyngeal carcinoma. Proc Natl Acad Sci U S A (1992) 1.33
Cadmium carcinogenesis in male Wistar [Crl:(WI)BR] rats: dose-response analysis of tumor induction in the prostate and testes and at the injection site. Cancer Res (1988) 1.32
Suppression of in vivo tumor growth and induction of suspension cell death by tissue inhibitor of metalloproteinases (TIMP)-3. Carcinogenesis (1996) 1.32
Expression of metalloproteinase genes in human prostate cancer. J Cancer Res Clin Oncol (1991) 1.31
Increased ROS levels contribute to elevated transcription factor and MAP kinase activities in malignantly progressed mouse keratinocyte cell lines. Carcinogenesis (1999) 1.31
Studies on the mechanism of skin tumor promotion. Cancer Res (1970) 1.29
Sclerosing cholangitis in ulcerative colitis. Scand J Gastroenterol (1980) 1.28
13-cis-retinoic acid: inhibition of bladder carcinogenesis in the rat. Science (1977) 1.27
Targeted disruption of the epidermal growth factor receptor impairs growth of squamous papillomas expressing the v-ras(Ha) oncogene but does not block in vitro keratinocyte responses to oncogenic ras. Cancer Res (1997) 1.27