Published in Biochemistry on February 22, 1977
Purification and mechanism of human aldehyde oxidase expressed in Escherichia coli. Drug Metab Dispos (2009) 0.99
Mechanistic studies of para-substituted N,N'-dibenzyl-1,4-diaminobutanes as substrates for a mammalian polyamine oxidase. Biochemistry (2009) 0.91
Interactions of nicotinamide-adenine dinucleotide phosphate analogues and fragments with pigeon liver malic enzyme. Synergistic effect between the nicotinamide and adenine moieties. Biochem J (1987) 0.82
Solvent isotope and viscosity effects on the steady-state kinetics of the flavoprotein nitroalkane oxidase. FEBS Lett (2013) 0.79
Role of the divalent metal ion in the NAD:malic enzyme reaction: an ESEEM determination of the ground state conformation of malate in the E:Mn:malate complex. Protein Sci (1996) 0.75
The statistical analysis of enzyme kinetic data. Adv Enzymol Relat Areas Mol Biol (1967) 9.95
Statistical analysis of enzyme kinetic data. Methods Enzymol (1979) 9.49
Primary structure and biochemical properties of an M2 muscarinic receptor. Science (1987) 3.16
Partition analysis and the concept of net rate constants as tools in enzyme kinetics. Biochemistry (1975) 2.69
Determining the chemical mechanisms of enzyme-catalyzed reactions by kinetic studies. Adv Enzymol Relat Areas Mol Biol (1977) 2.62
Use of multiple isotope effects to determine enzyme mechanisms and intrinsic isotope effects. Malic enzyme and glucose-6-phosphate dehydrogenase. Biochemistry (1982) 2.22
Stability constants of Mg2+ and Cd2+ complexes of adenine nucleotides and thionucleotides and rate constants for formation and dissociation of MgATP and MgADP. Biochemistry (1984) 2.01
A specific and sensitive assay for disulfides. J Biol Chem (1968) 1.82
The use of pH studies to determine chemical mechanisms of enzyme-catalyzed reactions. Methods Enzymol (1982) 1.76
An M2 muscarinic receptor subtype coupled to both adenylyl cyclase and phosphoinositide turnover. Science (1987) 1.67
Isotope exchange studies of the mechanism of the reaction catalyzed by adenosine triphosphate: creatine phosphotransferase. J Biol Chem (1966) 1.55
Purification and kinetic studies of beef liver cytoplasmic aconitase. J Biol Chem (1967) 1.48
Tyrosine-48 is the proton donor and histidine-110 directs substrate stereochemical selectivity in the reduction reaction of human aldose reductase: enzyme kinetics and crystal structure of the Y48H mutant enzyme. Biochemistry (1994) 1.43
Use of isotope effects to elucidate enzyme mechanisms. CRC Crit Rev Biochem (1982) 1.41
Kinetic and chemical mechanisms of yeast formate dehydrogenase. Biochemistry (1980) 1.39
Some physical properties of palmityl-coenzyme A micelles. Biochim Biophys Acta (1968) 1.32
The kinetics of pig heart triphosphopyridine nucleotide-isocitrate dehydrogenase. I. Initial velocity, substrate and product inhibition, and isotope exchange studies. J Biol Chem (1974) 1.28
Pigeon liver malic enzyme. V. Kinetic studies. J Biol Chem (1967) 1.25
The kinetics of pig heart triphosphopyridine nucleotide-isocitrate dehydrogenase. II. Dead-end and multiple inhibition studies. J Biol Chem (1974) 1.25
Kinetic studies of yeast nucleoside diphosphate kinase. Biochemistry (1969) 1.23
Substrate inhibition. Methods Enzymol (1979) 1.22
Stereoselective preparation of deuterated reduced nicotinamide adenine nucleotides and substrates by enzymatic synthesis. Anal Biochem (1979) 1.21
Mechanistic deductions from isotope effects in multireactant enzyme mechanisms. Biochemistry (1981) 1.21
Catalytic effectiveness of human aldose reductase. Critical role of C-terminal domain. J Biol Chem (1992) 1.21
1-Acylglycerol 3-phosphate acyltransferase from rat liver. J Biol Chem (1969) 1.19
Interaction of [125I]-alpha-bungarotoxin with acetylcholine receptor from Torpedo californica. Biochemistry (1979) 1.18
Rat liver pyruvate carboxylase. II. Kinetic studies of the forward reaction. J Biol Chem (1971) 1.16
Influence of salt, substrate, and cofactor concentrations on the kinetic and mechanistic behavior of phosphoglycerate mutase. Biochemistry (1968) 1.15
Secondary deuterium and nitrogen-15 isotope effects in enzyme-catalyzed reactions. Chemical mechanism of liver alcohol dehydrogenase. Biochemistry (1981) 1.15
The inhibition of acetate, pyruvate, and 3-phosphogylcerate kinases by chromium adenosine triphosphate. J Biol Chem (1974) 1.14
Decarboxylation of oxalacetate by pyruvate carboxylase. Biochemistry (1986) 1.13
Bovine liver fructokinase: purification and kinetic properties. Biochemistry (1977) 1.13
Kinetic studies of Escherichia coli galactokinase. Biochemistry (1968) 1.13
Interaction of metal(III)-adenosine 5'-triphosphate complexes with yeast hexokinase. Biochemistry (1980) 1.12
Variation of transition-state structure as a function of the nucleotide in reactions catalyzed by dehydrogenases. 2. Formate dehydrogenase. Biochemistry (1984) 1.12
Fractionation factors and activation energies for exchange of the low barrier hydrogen bonding proton in peptidyl trifluoromethyl ketone complexes of chymotrypsin. Proc Natl Acad Sci U S A (1998) 1.12
Kinetics of the uracil-DNA glycosylase/inhibitor protein association. Ung interaction with Ugi, nucleic acids, and uracil compounds. J Biol Chem (1993) 1.12
pH profiles and isotope effects for aconitases from Saccharomycopsis lipolytica, beef heart, and beef liver. alpha-Methyl-cis-aconitate and threo-Ds-alpha-methylisocitrate as substrates. Biochemistry (1984) 1.11
Relationship of the oxidation state of the iron-sulfur cluster of aconitase to activity and substrate binding. Biochemistry (1981) 1.10
Inhibition of isocitrate lyase by 3-nitropropionate, a reaction-intermediate analogue. Biochemistry (1982) 1.09
Mechanism of action of the nonspecific phosphomonoesterase from potatoes. Biochemistry (1966) 1.09
Equilibrium perturbation by isotope substitution. Biochemistry (1975) 1.09
Optimizing coupled enzyme assays. Anal Biochem (1979) 1.07
High resolution X-ray structure of dTDP-glucose 4,6-dehydratase from Streptomyces venezuelae. J Biol Chem (2003) 1.07
Fatty acid synthetase. A steady state kinetic analysis of the reaction catalyzed by the enzyme from pigeon liver. J Biol Chem (1975) 1.06
Mechanism of human aldehyde reductase: characterization of the active site pocket. Biochemistry (1995) 1.06
Determination of the mechanism of orotidine 5'-monophosphate decarboxylase by isotope effects. Biochemistry (2000) 1.06
Nitro analogues of citrate and isocitrate as transition-state analogues for aconitase. Biochemistry (1980) 1.05
pH variation of isotope effects in enzyme-catalyzed reactions. 2. Isotope-dependent step not pH dependent. Kinetic mechanism of alcohol dehydrogenase. Biochemistry (1981) 1.04
Kinetic mechanism of glutamate dehydrogenase. Biochemistry (1980) 1.04
Rabbit muscle phosphofructokinase. II. Product and dead end inhibition. J Biol Chem (1974) 1.04
Derivation of rate equations for multisite ping-pong mechanisms with ping-pong reactions at one or more sites. J Biol Chem (1973) 1.03
Use of pH studies to elucidate the catalytic mechanism of rabbit muscle creatine kinase. Biochemistry (1981) 1.03
Slow-binding inhibition: the general case. Biochim Biophys Acta (1996) 1.03
Transition-state structures for enzymatic and alkaline phosphotriester hydrolysis. Biochemistry (1991) 1.02
Use of nitrogen-15 and deuterium isotope effects to determine the chemical mechanism of phenylalanine ammonia-lyase. Biochemistry (1985) 1.02
Use of multiple isotope effects to study the mechanism of 6-phosphogluconate dehydrogenase. Biochemistry (1984) 1.02
pH variation of isotope effects in enzyme-catalyzed reactions. 1. Isotope- and pH-dependent steps the same. Biochemistry (1981) 1.02
Studies on the microsomal acylation of L-glycerol-3-phosphate. II. The specificity and properties of the rat liver enzyme. Biochim Biophys Acta (1969) 1.01
A source of response regulator autophosphatase activity: the critical role of a residue adjacent to the Spo0F autophosphorylation active site. Biochemistry (1998) 1.01
Physical properties of the purified cardiac muscarinic acetylcholine receptor. Biochemistry (1986) 1.00
Purification of the muscarinic acetylcholine receptor from porcine atria. Proc Natl Acad Sci U S A (1984) 1.00
Thermal denaturation of Escherichia coli thioredoxin studied by hydrogen/deuterium exchange and electrospray ionization mass spectrometry: monitoring a two-state protein unfolding transition. Biochemistry (1999) 0.99
The substrate and anomeric specificity of fructokinase. J Biol Chem (1973) 0.98
Large scale preparation and characterization of membrane-bound and detergent-solubilized muscarinic acetylcholine receptor from pig atria. Prep Biochem (1984) 0.98
Variation of transition-state structure as a function of the nucleotide in reactions catalyzed by dehydrogenases. 1. Liver alcohol dehydrogenase with benzyl alcohol and yeast aldehyde dehydrogenase with benzaldehyde. Biochemistry (1984) 0.98
Mechanisms of enzymatic and acid-catalyzed decarboxylations of prephenate. Biochemistry (1984) 0.98
The use of isotope effects to determine transition-state structure for enzymic reactions. Methods Enzymol (1982) 0.98
Sequence analysis of bovine lens aldose reductase. J Biol Chem (1990) 0.97
Kinetic and isotope-exchange studies on shikimate dehydrogenase from Pisum sativum. Biochemistry (1971) 0.97
Use of primary deuterium and 15N isotope effects to deduce the relative rates of steps in the mechanisms of alanine and glutamate dehydrogenases. Biochemistry (1988) 0.97
pH variation of the kinetic parameters and the catalytic mechanism of malic enzyme. Biochemistry (1977) 0.97
Use of isotope effects to deduce the chemical mechanism of fumarase. Biochemistry (1980) 0.97
Use of chromium-adenosine triphosphate and lyxose to elucidate the kinetic mechanism and coordination state of the nucleotide substrate for yeast hexokinase. Biochemistry (1975) 0.96
Ligand-induced changes in membrane-bound acetylcholine receptor observed by ethidium fluorescence. 2. Stopped-flow studies with agonists and antagonists. Biochemistry (1979) 0.96
pH properties and chemical mechanism of action of 3-hydroxy-3-methylglutaryl coenzyme A reductase. Biochemistry (1981) 0.96
Meanings of Ki for conventional and alternate-substrate inhibitors. Biochem Pharmacol (1981) 0.96
Rat liver pyruvate carboxylase. 3. Isotopic exchange studies of the first partial reaction. J Biol Chem (1971) 0.96
Purification and mechanism of action of hog liver mevalonic kinase. J Biol Chem (1970) 0.95
Studies of the microsomal acylation of L-glycerol-3-phosphate. I. The specificity of the rat brain enzyme. Biochim Biophys Acta (1969) 0.95
Evidence from nitrogen-15 and solvent deuterium isotope effects on the chemical mechanism of adenosine deaminase. Biochemistry (1987) 0.95
15N kinetic isotope effects on uncatalyzed and enzymatic deamination of cytidine. Biochemistry (2002) 0.95
Mechanistic roles of Thr134, Tyr160, and Lys 164 in the reaction catalyzed by dTDP-glucose 4,6-dehydratase. Biochemistry (2001) 0.95
Purification and kinetic studies of the citrate cleavage enzyme. J Biol Chem (1967) 0.94
Isotope effect studies of the chemical mechanism of pig heart NADP isocitrate dehydrogenase. Biochemistry (1988) 0.94
Kinetics and mechanism of benzoylformate decarboxylase using 13C and solvent deuterium isotope effects on benzoylformate and benzoylformate analogues. Biochemistry (1988) 0.94
Reaction intermediate analogues for enolase. Biochemistry (1984) 0.93
Primary and secondary deuterium isotope effects on equilibrium constants for enzyme-catalyzed reactions. Biochemistry (1980) 0.93
Substrate activity of (adenosine triphosphato)tetraamminecobalt(III) with yeast hexokinase and separation of diastereomers using the enzyme. Biochemistry (1978) 0.93
Response. Science (1995) 0.93
Isolation and characterization of monoclonal antibodies specific for the cardiac muscarinic acetylcholine receptor. Biochemistry (1987) 0.92
Determination of the chemical mechanism of glutamate dehydrogenase from pH studies. Biochemistry (1980) 0.92
Kinetics of aminoacyl-tRNA synthetases catalyzed ATP-PPi exchange. Methods Enzymol (1974) 0.92
Substrate synergism and the kinetic mechanism of yeast hexokinase. Biochemistry (1982) 0.92
Measurement of isotope effects by the equilibrium perturbation technique. Methods Enzymol (1980) 0.92
The fate of the hydrogens of phosphoenolpyruvate in the reaction catalyzed by 5-enolpyruvylshikimate-3-phosphate synthase. Isotope effects and isotope exchange. J Biol Chem (1982) 0.92
Inhibition of creatine kinase by chromium nucleotides. J Biol Chem (1973) 0.91