Published in Oncogene on August 01, 1992
Transforming growth factor beta effects on expression of G1 cyclins and cyclin-dependent protein kinases. Proc Natl Acad Sci U S A (1993) 1.89
RNA fingerprinting using arbitrarily primed PCR identifies differentially regulated RNAs in mink lung (Mv1Lu) cells growth arrested by transforming growth factor beta 1. Proc Natl Acad Sci U S A (1993) 1.72
A role for transcriptional repression of p21CIP1 by c-Myc in overcoming transforming growth factor beta -induced cell-cycle arrest. Proc Natl Acad Sci U S A (2000) 1.61
Complementation by wild-type p53 of interleukin-6 effects on M1 cells: induction of cell cycle exit and cooperativity with c-myc suppression. Mol Cell Biol (1993) 1.56
Interactions among regulators of RNA abundance characterized using RNA fingerprinting by arbitrarily primed PCR. Nucleic Acids Res (1994) 1.07
Effects of transforming growth factor beta-1 on growth-regulatory genes in tumour-derived human oral keratinocytes. Br J Cancer (1995) 0.82
Abrogation of transforming growth factor-beta signaling in pancreatic cancer. World J Surg (2005) 0.79
Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line. J Cell Biol (1988) 16.82
SKP2 is required for ubiquitin-mediated degradation of the CDK inhibitor p27. Nat Cell Biol (1999) 9.92
Wild-type p53 induces apoptosis of myeloid leukaemic cells that is inhibited by interleukin-6. Nature (1991) 9.21
Cyclin D1 is a nuclear protein required for cell cycle progression in G1. Genes Dev (1993) 8.03
Cyclin A is required at two points in the human cell cycle. EMBO J (1992) 7.96
Cooperation between gene encoding p53 tumour antigen and ras in cellular transformation. Nature (1985) 7.07
Human cyclin E, a nuclear protein essential for the G1-to-S phase transition. Mol Cell Biol (1995) 6.41
Life and death partners: apoptosis, autophagy and the cross-talk between them. Cell Death Differ (2009) 5.28
Increased proteasome-dependent degradation of the cyclin-dependent kinase inhibitor p27 in aggressive colorectal carcinomas. Nat Med (1997) 5.10
Reversible tyrosine phosphorylation of cdc2: dephosphorylation accompanies activation during entry into mitosis. Cell (1989) 4.68
Human p53 gene localized to short arm of chromosome 17. Nature (1986) 4.67
Insights into SCF ubiquitin ligases from the structure of the Skp1-Skp2 complex. Nature (2000) 4.52
The cdc2 kinase is a nuclear protein that is essential for mitosis in mammalian cells. Cell (1989) 4.43
Phosphorylation and activation of human cdc25-C by cdc2--cyclin B and its involvement in the self-amplification of MPF at mitosis. EMBO J (1993) 4.33
Ubiquitination of p27 is regulated by Cdk-dependent phosphorylation and trimeric complex formation. Genes Dev (1999) 4.07
Molecular and cytogenetic analysis of immortalized human primary keratinocytes obtained after transfection with human papillomavirus type 16 DNA. Oncogene (1987) 4.02
Short-term effects of carbon monoxide exposure on the exercise performance of subjects with coronary artery disease. N Engl J Med (1989) 4.02
The F-box protein family. Genome Biol (2000) 4.00
p13suc1 acts in the fission yeast cell division cycle as a component of the p34cdc2 protein kinase. EMBO J (1987) 3.91
The cell-cycle regulatory protein Cks1 is required for SCF(Skp2)-mediated ubiquitinylation of p27. Nat Cell Biol (2001) 3.87
Viral load and disease progression in infants infected with human immunodeficiency virus type 1. Women and Infants Transmission Study Group. N Engl J Med (1997) 3.71
Regulation of the cdk inhibitor p27 and its deregulation in cancer. J Cell Physiol (2000) 3.65
Do clinical markers of barotrauma and oxygen toxicity explain interhospital variation in rates of chronic lung disease? The Neonatology Committee for the Developmental Network. Pediatrics (2000) 3.48
Guidelines for the use and interpretation of assays for monitoring cell death in higher eukaryotes. Cell Death Differ (2009) 3.44
Identification of a novel serine/threonine kinase and a novel 15-kD protein as potential mediators of the gamma interferon-induced cell death. Genes Dev (1995) 3.37
The human F box protein beta-Trcp associates with the Cul1/Skp1 complex and regulates the stability of beta-catenin. Oncogene (1999) 3.36
Identification of a family of human F-box proteins. Curr Biol (1999) 3.31
Abelson murine leukemia virus-induced tumors elicit antibodies against a host cell protein, P50. J Virol (1980) 3.30
Oncogenic mutations of the p53 tumor suppressor: the demons of the guardian of the genome. Cancer Res (2000) 3.30
cdc2 phosphorylation is required for its interaction with cyclin. EMBO J (1991) 3.22
Major deletions in the gene encoding the p53 tumor antigen cause lack of p53 expression in HL-60 cells. Proc Natl Acad Sci U S A (1985) 3.15
Identification of p34 and p13, human homologs of the cell cycle regulators of fission yeast encoded by cdc2+ and suc1+. Cell (1987) 3.12
A 60 kd cdc2-associated polypeptide complexes with the E1A proteins in adenovirus-infected cells. Cell (1989) 3.08
Reconstitution of p53 expression in a nonproducer Ab-MuLV-transformed cell line by transfection of a functional p53 gene. Cell (1984) 3.05
CDC25 phosphatases as potential human oncogenes. Science (1995) 2.84
Regulation of the cell cycle by the cdk2 protein kinase in cultured human fibroblasts. J Cell Biol (1993) 2.83
Nuclear accumulation of p53 protein is mediated by several nuclear localization signals and plays a role in tumorigenesis. Mol Cell Biol (1990) 2.73
Meth A fibrosarcoma cells express two transforming mutant p53 species. Oncogene (1988) 2.71
The death domain: a module shared by proteins with diverse cellular functions. Trends Biochem Sci (1995) 2.70
DAP-kinase is a Ca2+/calmodulin-dependent, cytoskeletal-associated protein kinase, with cell death-inducing functions that depend on its catalytic activity. EMBO J (1997) 2.69
Halting angiogenesis suppresses carcinoma cell invasion. Nat Med (1997) 2.61
Activation of the phosphatase activity of human cdc25A by a cdk2-cyclin E dependent phosphorylation at the G1/S transition. EMBO J (1994) 2.61
Increased concentration of an apparently identical cellular protein in cells transformed by either Abelson murine leukemia virus or other transforming agents. J Virol (1981) 2.56
Role of the F-box protein Skp2 in lymphomagenesis. Proc Natl Acad Sci U S A (2001) 2.55
Absence of host plasminogen activator inhibitor 1 prevents cancer invasion and vascularization. Nat Med (1998) 2.54
Close link between reduction of c-myc expression by interferon and, G0/G1 arrest. Nature (1985) 2.47
Risk of oral squamous cell carcinoma in 402 patients with oral lichen planus: a follow-up study in an Italian population. Oral Oncol (2004) 2.46
p27 cytoplasmic localization is regulated by phosphorylation on Ser10 and is not a prerequisite for its proteolysis. EMBO J (2001) 2.45
DAP kinase links the control of apoptosis to metastasis. Nature (1997) 2.39
Association of cdk2 kinase with the transcription factor E2F during S phase. Science (1992) 2.37
Cathepsin D protease mediates programmed cell death induced by interferon-gamma, Fas/APO-1 and TNF-alpha. EMBO J (1996) 2.36
c-Jun and JunB antagonistically control cytokine-regulated mesenchymal-epidermal interaction in skin. Cell (2000) 2.35
Differential modulation of cyclin gene expression by MYC. Proc Natl Acad Sci U S A (1993) 2.31
A likelihood-based method for real-time estimation of the serial interval and reproductive number of an epidemic. Stat Med (2008) 2.29
p53-mediated cell death: relationship to cell cycle control. Mol Cell Biol (1993) 2.27
Immunologically distinct p53 molecules generated by alternative splicing. Mol Cell Biol (1986) 2.20
Differential expression and regulation of Cyclin D1 protein in normal and tumor human cells: association with Cdk4 is required for Cyclin D1 function in G1 progression. Oncogene (1994) 2.18
Activation of protein kinase C triggers its ubiquitination and degradation. Mol Cell Biol (1998) 2.15
Using treatment failure under effective directly observed short-course chemotherapy programs to identify patients with multidrug-resistant tuberculosis. Int J Tuberc Lung Dis (2000) 2.15
Molecular basis for heterogeneity of the human p53 protein. Mol Cell Biol (1986) 2.14
Cyclin D1 protein oscillates and is essential for cell cycle progression in human tumour cell lines. Oncogene (1994) 2.10
DAP kinase activates a p19ARF/p53-mediated apoptotic checkpoint to suppress oncogenic transformation. Nat Cell Biol (2001) 2.09
Prognostic role of the cyclin-dependent kinase inhibitor p27 in non-small cell lung cancer. Cancer Res (1997) 2.05
Enhanced ribosomal association of p27(Kip1) mRNA is a mechanism contributing to accumulation during growth arrest. J Biol Chem (1997) 2.05
p53, a transformation-related cellular-encoded protein, can be used as a biochemical marker for the detection of primary mouse tumor cells. Proc Natl Acad Sci U S A (1983) 2.03
Csk inhibition of c-Src activity requires both the SH2 and SH3 domains of Src. EMBO J (1993) 2.02
Wnt/beta-catenin signaling induces the expression and activity of betaTrCP ubiquitin ligase receptor. Mol Cell (2000) 2.02
The cell cycle inhibitor p27 is an independent prognostic marker in small (T1a,b) invasive breast carcinomas. Cancer Res (1997) 2.00
Inactivation of p53 gene expression by an insertion of Moloney murine leukemia virus-like DNA sequences. Mol Cell Biol (1984) 2.00
DAP-kinase is a mediator of endoplasmic reticulum stress-induced caspase activation and autophagic cell death. Cell Death Differ (2008) 1.99
Hunger in children in the United States: potential behavioral and emotional correlates. Pediatrics (1998) 1.99
Isolation of two interferon-induced translational inhibitors: a protein kinase and an oligo-isoadenylate synthetase. Proc Natl Acad Sci U S A (1978) 1.97
Mutant p53 proteins bind DNA abnormally in vitro. Oncogene (1991) 1.96
The plasminogen activator inhibitor PAI-1 controls in vivo tumor vascularization by interaction with proteases, not vitronectin. Implications for antiangiogenic strategies. J Cell Biol (2001) 1.94
White matter disorders of prematurity: association with intraventricular hemorrhage and ventriculomegaly. The Developmental Epidemiology Network. J Pediatr (1999) 1.93
Identification of a Myc-dependent step during the formation of active G1 cyclin-cdk complexes. EMBO J (1995) 1.92
Loss or altered subcellular localization of p27 in Barrett's associated adenocarcinoma. Cancer Res (1998) 1.92
DAP-5, a novel homolog of eukaryotic translation initiation factor 4G isolated as a putative modulator of gamma interferon-induced programmed cell death. Mol Cell Biol (1997) 1.90
A genetic tool used to identify thioredoxin as a mediator of a growth inhibitory signal. Science (1991) 1.89
Differential expression and cell cycle regulation of the cyclin-dependent kinase 4 inhibitor p16Ink4. Cancer Res (1994) 1.88
Dephosphorylation of cdc25-C by a type-2A protein phosphatase: specific regulation during the cell cycle in Xenopus egg extracts. Mol Biol Cell (1993) 1.87
Rearrangements in the p53 gene in Philadelphia chromosome positive chronic myelogenous leukemia. Blood (1989) 1.85
DAP-kinase participates in TNF-alpha- and Fas-induced apoptosis and its function requires the death domain. J Cell Biol (1999) 1.85
Nuclear localization is essential for the activity of p53 protein. Oncogene (1991) 1.83
Regulation of the microtubule nucleating activity of centrosomes in Xenopus egg extracts: role of cyclin A-associated protein kinase. J Cell Biol (1992) 1.82
Tumorigenic conversion of immortal human keratinocytes through stromal cell activation. Proc Natl Acad Sci U S A (1998) 1.82
Activation of human CDC2 protein as a histone H1 kinase is associated with complex formation with the p62 subunit. Proc Natl Acad Sci U S A (1989) 1.80
Transcription regulation by mutant p53. Oncogene (2007) 1.78
Wild-type but not mutant p53 can repress transcription initiation in vitro by interfering with the binding of basal transcription factors to the TATA motif. Oncogene (1993) 1.77
Autocrine beta-related interferon controls c-myc suppression and growth arrest during hematopoietic cell differentiation. Cell (1986) 1.73
A novel form of DAP5 protein accumulates in apoptotic cells as a result of caspase cleavage and internal ribosome entry site-mediated translation. Mol Cell Biol (2000) 1.72
Isolation of a full-length mouse cDNA clone coding for an immunologically distinct p53 molecule. Mol Cell Biol (1985) 1.72
c-Myc trans-activates the p53 promoter through a required downstream CACGTG motif. Cell Growth Differ (1993) 1.72
Rescue of defective mitogenic signaling by D-type cyclins. Proc Natl Acad Sci U S A (1995) 1.71
Role of the F-box protein Skp2 in adhesion-dependent cell cycle progression. J Cell Biol (2001) 1.69