Published in Circ Res on November 01, 1992
T lymphocytes from human atherosclerotic plaques recognize oxidized low density lipoprotein. Proc Natl Acad Sci U S A (1995) 3.54
Persistent inhibition of cell respiration by nitric oxide: crucial role of S-nitrosylation of mitochondrial complex I and protective action of glutathione. Proc Natl Acad Sci U S A (1998) 3.10
Inflammatory cytokines in vascular dysfunction and vascular disease. Biochem Pharmacol (2009) 3.05
Evidence for apoptosis in advanced human atheroma. Colocalization with interleukin-1 beta-converting enzyme. Am J Pathol (1995) 2.54
What is the real physiological NO concentration in vivo? Nitric Oxide (2009) 1.88
Abnormal contractile function due to induction of nitric oxide synthesis in rat cardiac myocytes follows exposure to activated macrophage-conditioned medium. J Clin Invest (1993) 1.54
Circulating neutrophils maintain physiological blood pressure by suppressing bacteria and IFNgamma-dependent iNOS expression in the vasculature of healthy mice. Blood (2008) 1.53
Role of tumour necrosis factor in the induction of nitric oxide synthase in a rat model of endotoxin shock. Br J Pharmacol (1993) 1.40
Regulation of endothelial function by mitochondrial reactive oxygen species. Antioxid Redox Signal (2011) 1.25
Attenuation of the induction of nitric oxide synthase by endogenous glucocorticoids accounts for endotoxin tolerance in vivo. Proc Natl Acad Sci U S A (1994) 1.23
Arterial smooth muscle cells express nitric oxide synthase in response to endothelial injury. J Exp Med (1994) 1.14
The role of nitric oxide in cardiac depression induced by interleukin-1 beta and tumour necrosis factor-alpha. Br J Pharmacol (1995) 1.12
Nitric oxide deficiency in pulmonary hypertension: Pathobiology and implications for therapy. Pulm Circ (2013) 1.05
The lethal effects of cytokine-induced nitric oxide on cardiac myocytes are blocked by nitric oxide synthase antagonism or transforming growth factor beta. J Clin Invest (1995) 1.05
Assessing the physiological concentration and targets of nitric oxide in brain tissue. J Physiol (2008) 1.03
Altered regulation of inducible nitric oxide synthase expression in macrophages from senescent mice. Infect Immun (1996) 1.01
Induction of nitric oxide production by polyosides from the cell walls of Streptococcus mutans OMZ 175, a gram-positive bacterium, in the rat aorta. Infect Immun (1997) 0.96
Chronic exposure to nitric oxide alters the free iron pool in endothelial cells: role of mitochondrial respiratory complexes and heat shock proteins. Proc Natl Acad Sci U S A (2003) 0.95
Integrative pathway dissection of molecular mechanisms of moxLDL-induced vascular smooth muscle phenotype transformation. BMC Cardiovasc Disord (2013) 0.95
Effect of recombinant human tumor necrosis factor-alpha on cerebral oxygen uptake, cerebrospinal fluid lactate, and cerebral blood flow in the rabbit: role of nitric oxide. J Clin Invest (1995) 0.93
Continuous exposure to high concentrations of nitric oxide leads to persistent inhibition of oxygen consumption by J774 cells as well as extraction of oxygen by the extracellular medium. Biochem J (2000) 0.90
Inducible and endothelial nitric oxide synthase expression during development of transplant arteriosclerosis in rat aortic grafts. Am J Pathol (1996) 0.89
Induction of L-arginine transport and nitric oxide synthase in vascular smooth muscle cells: synergistic actions of pro-inflammatory cytokines and bacterial lipopolysaccharide. Br J Pharmacol (1995) 0.88
Regulation of smooth muscle cell growth by endothelium-derived factors. Tex Heart Inst J (1994) 0.88
Increased expression of bFGF is associated with carotid atherosclerotic plaques instability engaging the NF-κB pathway. J Cell Mol Med (2010) 0.83
Myocardial calcium-independent nitric oxide synthase activity is present in dilated cardiomyopathy, myocarditis, and postpartum cardiomyopathy but not in ischaemic or valvar heart disease. Br Heart J (1995) 0.83
Linking immunity to atherosclerosis: implications for vascular pharmacology--a tribute to Göran K. Hansson. Vascul Pharmacol (2011) 0.79
Excess no predisposes mitochondrial succinate-cytochrome c reductase to produce hydroxyl radical. Biochim Biophys Acta (2011) 0.79
A journey in science: medical scientist in translation. Mol Med (2014) 0.76
Tumor necrosis factor (TNF) and nitric oxide (NO) mediate the acute cardiovascular effects of endotoxemia. Ann Surg (1997) 0.75
IL-4 Protects the Mitochondria Against TNFα and IFNγ Induced Insult During Clearance of Infection with Citrobacter rodentium and Escherichia coli. Sci Rep (2015) 0.75
Autocrine growth inhibition of IL-1 beta-treated cultured human aortic smooth muscle cells: possible role of nitric oxide. Heart Vessels (1996) 0.75
H89 enhances the sensitivity of cancer cells to glyceryl trinitrate through a purinergic receptor-dependent pathway. Oncotarget (2015) 0.75
Tumor Necrosis Factor a Promotes Phosphoinositide 3-Kinase Enhancer A and Amp-Activated Protein Kinase Interaction to Suppress Lipid Oxidation in Skeletal Muscle. Diabetes (2017) 0.75
Therapy with immunoglobulin in patients with acute myocarditis and cardiomyopathy: analysis of leukocyte balance. Heart Vessels (2013) 0.75
Regional accumulations of T cells, macrophages, and smooth muscle cells in the human atherosclerotic plaque. Arteriosclerosis (1986) 5.23
Treatment of hereditary tyrosinaemia type I by inhibition of 4-hydroxyphenylpyruvate dioxygenase. Lancet (1992) 4.23
T lymphocytes from human atherosclerotic plaques recognize oxidized low density lipoprotein. Proc Natl Acad Sci U S A (1995) 3.54
Cytokine expression in advanced human atherosclerotic plaques: dominance of pro-inflammatory (Th1) and macrophage-stimulating cytokines. Atherosclerosis (1999) 3.21
Transfer of CD4(+) T cells aggravates atherosclerosis in immunodeficient apolipoprotein E knockout mice. Circulation (2000) 3.17
Involvement of the immune system in human atherogenesis: current knowledge and unanswered questions. Lab Invest (1991) 2.76
Progressive increase of the mutated mitochondrial DNA fraction in Kearns-Sayre syndrome. Pediatr Res (1990) 2.47
Superoxide dismutase in extracellular fluids. Clin Chim Acta (1982) 2.32
Hypercholesterolemia is associated with a T helper (Th) 1/Th2 switch of the autoimmune response in atherosclerotic apo E-knockout mice. J Clin Invest (1998) 2.27
Expression of class II transplantation antigen on vascular smooth muscle cells in human atherosclerosis. J Clin Invest (1985) 2.16
T lymphocytes in human atherosclerotic plaques are memory cells expressing CD45RO and the integrin VLA-1. Arterioscler Thromb (1992) 2.09
Mitochondrial encephalomyopathies in childhood. I. Biochemical and morphologic investigations. J Pediatr (1991) 2.04
Cardiomyopathy in children with mitochondrial disease; clinical course and cardiological findings. Eur Heart J (2003) 1.95
Evidence for a local immune response in atherosclerosis. CD4+ T cells infiltrate lesions of apolipoprotein-E-deficient mice. Am J Pathol (1996) 1.88
Interferon-gamma inhibits scavenger receptor expression and foam cell formation in human monocyte-derived macrophages. J Clin Invest (1992) 1.83
Immunoglobulin treatment reduces atherosclerosis in apo E knockout mice. J Clin Invest (1998) 1.80
Segregation and manifestations of the mtDNA tRNA(Lys) A-->G(8344) mutation of myoclonus epilepsy and ragged-red fibers (MERRF) syndrome. Am J Hum Genet (1992) 1.73
Class II MHC antigen expression in the atherosclerotic plaque: smooth muscle cells express HLA-DR, HLA-DQ and the invariant gamma chain. Clin Exp Immunol (1986) 1.70
In vivo downregulation of T helper cell 1 immune responses reduces atherogenesis in apolipoprotein E-knockout mice. Circulation (2001) 1.69
Clonal expansion of mitochondrial DNA with multiple deletions in autosomal dominant progressive external ophthalmoplegia. Ann Neurol (1996) 1.69
Nuclear factor kappa-B and the heart. J Am Coll Cardiol (2001) 1.68
Humoral and cellular immune responses up to 7.5 years after administration of streptokinase for acute myocardial infarction. Eur Heart J (1999) 1.64
Low levels of mitochondrial transcription factor A in mitochondrial DNA depletion. Biochem Biophys Res Commun (1994) 1.63
Chlamydia pneumoniae infection does not induce or modify atherosclerosis in mice. Circulation (2001) 1.63
The incidence of mitochondrial encephalomyopathies in childhood: clinical features and morphological, biochemical, and DNA anbormalities. Ann Neurol (2001) 1.53
Recurrent metabolic decompensation in profound carnitine palmitoyltransferase II deficiency. J Pediatr (1993) 1.52
Correlations between clinical variables and gene-expression profiles in carotid plaque instability. Eur J Vasc Endovasc Surg (2011) 1.50
Genotype and phenotype in patients with dihydropyrimidine dehydrogenase deficiency. Hum Genet (1999) 1.48
Leber's hereditary optic neuropathy and complex I deficiency in muscle. Ann Neurol (1991) 1.46
Induction of B-type receptors for platelet-derived growth factor in vascular inflammation: possible implications for development of vascular proliferative lesions. Lancet (1988) 1.46
Automatic sequencing of mitochondrial tRNA genes in patients with mitochondrial encephalomyopathy. Biochim Biophys Acta (1994) 1.44
Apoptosis of vascular smooth muscle cells induced by in vitro stimulation with interferon-gamma, tumor necrosis factor-alpha, and interleukin-1 beta. Arterioscler Thromb Vasc Biol (1996) 1.41
IgA class anticardiolipin antibodies in cutaneous leukocytoclastic vasculitis. J Am Acad Dermatol (1996) 1.40
Induction of tenascin in rat arterial injury. Relationship to altered smooth muscle cell phenotype. Am J Pathol (1991) 1.39
LDL immunization induces T-cell-dependent antibody formation and protection against atherosclerosis. Arterioscler Thromb Vasc Biol (2001) 1.39
Reduced frequency of memory CD8+ T lymphocytes in cerebrospinal fluid and blood of patients with multiple sclerosis. Autoimmunity (1995) 1.39
Cyclosporin A inhibits smooth muscle proliferation in the vascular response to injury. Proc Natl Acad Sci U S A (1988) 1.38
Effects of sex and age on atherosclerosis and autoimmunity in apoE-deficient mice. Atherosclerosis (1999) 1.38
Polyclonal origin of T lymphocytes in human atherosclerotic plaques. Lab Invest (1991) 1.35
Oligoclonal T cell expansions in atherosclerotic lesions of apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol (2000) 1.30
Simultaneous A8344G heteroplasmy and mitochondrial DNA copy number quantification in myoclonus epilepsy and ragged-red fibers (MERRF) syndrome by a multiplex molecular beacon based real-time fluorescence PCR. Nucleic Acids Res (2001) 1.30
Myocardial infarction mediated by endothelin receptor signaling in hypercholesterolemic mice. Proc Natl Acad Sci U S A (1999) 1.28
Prelesional complement activation in experimental atherosclerosis. Terminal C5b-9 complement deposition coincides with cholesterol accumulation in the aortic intima of hypercholesterolemic rabbits. Lab Invest (1989) 1.21
Activation of inducible nitric oxide synthase/nitric oxide by curli fibers leads to a fall in blood pressure during systemic Escherichia coli infection in mice. J Infect Dis (2001) 1.19
Severe hypercholesterolaemia leads to strong Th2 responses to an exogenous antigen. Scand J Immunol (2004) 1.19
Smooth muscle cells express Ia antigens during arterial response to injury. Lab Invest (1988) 1.18
Interferon-gamma inhibits lipoprotein lipase in human monocyte-derived macrophages. Biochim Biophys Acta (1990) 1.18
Detection of B cells and proinflammatory cytokines in atherosclerotic plaques of hypercholesterolaemic apolipoprotein E knockout mice. Scand J Immunol (1999) 1.17
Endothelial dysfunction in response to psychosocial stress in monkeys. Circ Res (1991) 1.14
Fc-mediated binding of IgG to vimentin-type intermediate filaments in vascular endothelial cells. Proc Natl Acad Sci U S A (1984) 1.14
Complement receptors and regulatory proteins in human atherosclerotic lesions. Arteriosclerosis (1990) 1.13
Immunohistochemical localization of lipoprotein lipase in human adipose tissue. Atherosclerosis (1984) 1.12
Autoimmunity in atherosclerosis: a protective response losing control? J Intern Med (2008) 1.12
Cellular immunity, low-density lipoprotein and atherosclerosis: break of tolerance in the artery wall. Thromb Haemost (2011) 1.10
Decreased C3b receptors (CR1) on erythrocytes from patients with systemic lupus erythematosus. Clin Exp Immunol (1986) 1.09
Evidence for antigen-driven T-cell response in unstable angina. Circulation (2000) 1.09
Immunopathological features of rat Staphylococcus aureus arthritis. Infect Immun (1994) 1.08
Differential expression of scavenger receptor isoforms during monocyte-macrophage differentiation and foam cell formation. Arterioscler Thromb (1994) 1.07
Accumulation of IgG and complement factor C3 in human arterial endothelium and atherosclerotic lesions. Acta Pathol Microbiol Immunol Scand A (1984) 1.07
Overexpression of inducible nitric oxide synthase by neointimal smooth muscle cells. Circ Res (1998) 1.06
Immune mechanisms in atherosclerosis. Coron Artery Dis (1994) 1.06
Decreased aminoacylation of mutant tRNAs in MELAS but not in MERRF patients. Hum Mol Genet (2000) 1.05
Expression of inducible nitric oxide synthase inhibits platelet adhesion and restores blood flow in the injured artery. Circ Res (1996) 1.04
Human arterial smooth muscle cells in culture: inverse relationship between proliferation and expression of contractile proteins. In Vitro Cell Dev Biol (1989) 1.04
Possibilities for treatment and for early prenatal diagnosis of hereditary tyrosinaemia. Lancet (1985) 1.03
Ultrastructural studies on the localization of IgG in the aortic endothelium and subendothelial intima of atherosclerotic and nonatherosclerotic rabbits. Exp Mol Pathol (1980) 1.02
Mitochondrial DNA deletions and cytochrome c oxidase deficiency in muscle fibres. J Neurol Sci (1992) 1.01
Nuclear factor-kappa B regulates induction of apoptosis and inhibitor of apoptosis protein-1 expression in vascular smooth muscle cells. Circ Res (1999) 1.01
The macrophage scavenger receptor type A directs modified proteins to antigen presentation. Eur J Immunol (1999) 1.01
Expression of interleukin-15 in mouse and human atherosclerotic lesions. Am J Pathol (2001) 1.00
Mitochondrial DNA deletions in muscle fibers in inclusion body myositis. J Neuropathol Exp Neurol (1995) 1.00
Prevention of immune precipitation by purified components of the alternative pathway. Clin Exp Immunol (1985) 1.00
Evidence for cell death in the vascular endothelium in vivo and in vitro. Am J Pathol (1983) 1.00
Aortic endothelial cell death and replication in normal and lipopolysaccharide-treated rats. Am J Pathol (1985) 1.00
Human arterial smooth muscle cells in culture. Effects of platelet-derived growth factor and heparin on growth in vitro. Exp Cell Res (1988) 0.99
Mitochondrial DNA deletions in inclusion body myositis. Brain (1993) 0.99
Adhesion molecule expression on cerebrospinal fluid T lymphocytes: evidence for common recruitment mechanisms in multiple sclerosis, aseptic meningitis, and normal controls. Ann Neurol (1993) 0.98
Deficiency of mitochondrial ATP synthase of nuclear genetic origin. Neuromuscul Disord (2006) 0.96
Fc-dependent binding of monocytes to areas with endothelial injury in the rabbit aorta. Exp Mol Pathol (1981) 0.96
Augmented expression of inducible NO synthase in vascular smooth muscle cells during aging is associated with enhanced NF-kappaB activation. Arterioscler Thromb Vasc Biol (1999) 0.96
Decay-accelerating factor is expressed on vascular smooth muscle cells in human atherosclerotic lesions. J Clin Invest (1989) 0.96
Expression of the macrophage scavenger receptor in atheroma. Relationship to immune activation and the T-cell cytokine interferon-gamma. Arterioscler Thromb Vasc Biol (1995) 0.96
Neonatal screen for hereditary tyrosinaemia type I. Lancet (1992) 0.96
The antiviral cytomegalovirus inducible gene 5/viperin is expressed in atherosclerosis and regulated by proinflammatory agents. Arterioscler Thromb Vasc Biol (2005) 0.95
MHC class II antigen expression in human vascular smooth muscle cells is induced by interferon-gamma and modulated by tumour necrosis factor and lymphotoxin. Immunology (1990) 0.95
Expression of cyclo-oxygenase-2 in human atherosclerotic carotid arteries. Eur J Vasc Endovasc Surg (2000) 0.95
Retinoic acid regulates arterial smooth muscle cell proliferation and phenotypic features in vivo and in vitro through an RARalpha-dependent signaling pathway. Arterioscler Thromb Vasc Biol (1999) 0.95
A kinetic study of thymine 7-hydroxylase from neurospora crassa. Biochemistry (1975) 0.94
Ophthalmological findings in children and young adults with genetically verified mitochondrial disease. Br J Ophthalmol (2010) 0.94
Lipoprotein lipase in atherosclerosis: its presence in smooth muscle cells and absence from macrophages. J Lipid Res (1987) 0.94
Isolation and characterization of endothelial cells from the epididymal fat pad of the rat. J Lipid Res (1983) 0.93
Lack of transmission of deleted mtDNA from a woman with Kearns-Sayre syndrome to her child. Am J Hum Genet (1992) 0.93
Threshold expression of the tRNA(Lys) A8344G mutation in single muscle fibres. Neuromuscul Disord (1998) 0.93
Cytokine-induced expression of nitric oxide synthase results in nitrosylation of heme and nonheme iron proteins in vascular smooth muscle cells. Exp Cell Res (1994) 0.92
Two new mutations in the MTATP6 gene associated with Leigh syndrome. Neuropediatrics (2005) 0.92
Progressive encephalopathy and complex I deficiency associated with mutations in MTND1. Neuropediatrics (2008) 0.92
Complement activation in Henoch-Schönlein purpura. Pediatr Nephrol (1997) 0.92
Genetic variants of TNFSF4 and risk for carotid artery disease and stroke. J Mol Med (Berl) (2008) 0.91
Unstable angina activates myocardial heat shock protein 72, endothelial nitric oxide synthase, and transcription factors NFkappaB and AP-1. Cardiovasc Res (2000) 0.91