Human arterial smooth muscle cells in culture: inverse relationship between proliferation and expression of contractile proteins.

PubWeight™: 1.04‹?› | Rank: Top 15%

🔗 View Article (PMID 2661518)

Published in In Vitro Cell Dev Biol on June 01, 1989

Authors

G Fager1, G K Hansson, A M Gown, D M Larson, O Skalli, G Bondjers

Author Affiliations

1: Department of Medicine I, University of Göteborg, Sweden.

Articles by these authors

A monoclonal antibody against alpha-smooth muscle actin: a new probe for smooth muscle differentiation. J Cell Biol (1986) 6.83

Regional accumulations of T cells, macrophages, and smooth muscle cells in the human atherosclerotic plaque. Arteriosclerosis (1986) 5.23

Persistent and therapeutic concentrations of human factor IX in mice after hepatic gene transfer of recombinant AAV vectors. Nat Genet (1997) 4.72

Alpha-smooth muscle actin is transiently expressed by myofibroblasts during experimental wound healing. Lab Invest (1990) 4.67

Human atherosclerosis. II. Immunocytochemical analysis of the cellular composition of human atherosclerotic lesions. Am J Pathol (1986) 4.51

Clear cell tumor of the lung. Immunohistochemical and ultrastructural evidence of melanogenesis. Am J Surg Pathol (1991) 4.48

Characterization of the early lesion of 'degenerative' valvular aortic stenosis. Histological and immunohistochemical studies. Circulation (1994) 4.32

T lymphocytes from human atherosclerotic plaques recognize oxidized low density lipoprotein. Proc Natl Acad Sci U S A (1995) 3.54

Analysis of proliferative grade using anti-PCNA/cyclin monoclonal antibodies in fixed, embedded tissues. Comparison with flow cytometric analysis. Am J Pathol (1989) 3.43

Expression of myogenic regulatory proteins (myogenin and MyoD1) in small blue round cell tumors of childhood. Am J Pathol (1995) 3.37

Localization of PDGF-B protein in macrophages in all phases of atherogenesis. Science (1990) 3.27

Cytokine expression in advanced human atherosclerotic plaques: dominance of pro-inflammatory (Th1) and macrophage-stimulating cytokines. Atherosclerosis (1999) 3.21

Transfer of CD4(+) T cells aggravates atherosclerosis in immunodeficient apolipoprotein E knockout mice. Circulation (2000) 3.17

Specificity of HercepTest in determining HER-2/neu status of breast cancers using the United States Food and Drug Administration-approved scoring system. J Clin Oncol (1999) 3.04

HHF35, a muscle-actin-specific monoclonal antibody. I. Immunocytochemical and biochemical characterization. Am J Pathol (1987) 2.91

Involvement of the immune system in human atherogenesis: current knowledge and unanswered questions. Lab Invest (1991) 2.76

Expression of smooth muscle cell phenotype by rat mesangial cells in immune complex nephritis. Alpha-smooth muscle actin is a marker of mesangial cell proliferation. J Clin Invest (1991) 2.58

Apolipoprotein(a) and ischaemic heart disease in familial hypercholesterolaemia. Lancet (1990) 2.55

HER-2/neu protein expression in breast cancer evaluated by immunohistochemistry. A study of interlaboratory agreement. Am J Clin Pathol (2000) 2.53

Monoclonal antibodies to intermediate filament proteins of human cells: unique and cross-reacting antibodies. J Cell Biol (1982) 2.45

Monoclonal antibodies to human intermediate filament proteins. II. Distribution of filament proteins in normal human tissues. Am J Pathol (1984) 2.42

A smooth muscle-specific monoclonal antibody recognizes smooth muscle actin isozymes. J Cell Biol (1985) 2.38

Hypercholesterolemia is associated with a T helper (Th) 1/Th2 switch of the autoimmune response in atherosclerotic apo E-knockout mice. J Clin Invest (1998) 2.27

Immunocytochemical analysis of cellular components in atherosclerotic lesions. Use of monoclonal antibodies with the Watanabe and fat-fed rabbit. Arteriosclerosis (1986) 2.27

Detection of Chlamydia pneumoniae in aortic lesions of atherosclerosis by immunocytochemical stain. Arterioscler Thromb (1993) 2.27

Monoclonal antibodies specific for melanocytic tumors distinguish subpopulations of melanocytes. Am J Pathol (1986) 2.26

Expression of class II transplantation antigen on vascular smooth muscle cells in human atherosclerosis. J Clin Invest (1985) 2.16

Cytoskeleton of rat aortic smooth muscle cells. Normal conditions and experimental intimal thickening. Lab Invest (1984) 2.15

T lymphocytes in human atherosclerotic plaques are memory cells expressing CD45RO and the integrin VLA-1. Arterioscler Thromb (1992) 2.09

Smooth-muscle differentiation in stromal cells of malignant and non-malignant breast tissues. Int J Cancer (1988) 2.01

Application of photoshop-based image analysis to quantification of hormone receptor expression in breast cancer. J Histochem Cytochem (1997) 1.99

Evidence for a local immune response in atherosclerosis. CD4+ T cells infiltrate lesions of apolipoprotein-E-deficient mice. Am J Pathol (1996) 1.88

Direct evidence for a protein recognized by a monoclonal antibody against oxidatively modified LDL in atherosclerotic lesions from a Watanabe heritable hyperlipidemic rabbit. Am J Pathol (1989) 1.87

Interferon-gamma inhibits scavenger receptor expression and foam cell formation in human monocyte-derived macrophages. J Clin Invest (1992) 1.83

Immunoglobulin treatment reduces atherosclerosis in apo E knockout mice. J Clin Invest (1998) 1.80

Comparison of fluorescence in situ hybridization and immunohistochemistry for the evaluation of HER-2/neu in breast cancer. J Clin Oncol (1999) 1.77

Monitoring gene expression profile changes in ovarian carcinomas using cDNA microarray. Gene (1999) 1.73

Class II MHC antigen expression in the atherosclerotic plaque: smooth muscle cells express HLA-DR, HLA-DQ and the invariant gamma chain. Clin Exp Immunol (1986) 1.70

In vivo downregulation of T helper cell 1 immune responses reduces atherogenesis in apolipoprotein E-knockout mice. Circulation (2001) 1.69

Nuclear factor kappa-B and the heart. J Am Coll Cardiol (2001) 1.68

PDGF B-chain in neurons of the central nervous system, posterior pituitary, and in a transgenic model. Cell (1991) 1.67

Quality control in immunohistochemistry. Report of a workshop sponsored by the Biological Stain Commission. Am J Clin Pathol (1989) 1.65

Platelet-derived growth factor (PDGF) and PDGF receptor are induced in mesangial proliferative nephritis in the rat. Proc Natl Acad Sci U S A (1991) 1.64

Chlamydia pneumoniae infection does not induce or modify atherosclerosis in mice. Circulation (2001) 1.63

Fatty streak initiation in Watanabe Heritable Hyperlipemic and comparably hypercholesterolemic fat-fed rabbits. Arteriosclerosis (1987) 1.63

Thrombospondin in early human wound tissue. J Invest Dermatol (1987) 1.62

Induction of arteriosclerosis in normocholesterolemic rabbits by immunization with heat shock protein 65. Arterioscler Thromb (1992) 1.59

HHF35, a muscle actin-specific monoclonal antibody. II. Reactivity in normal, reactive, and neoplastic human tissues. Am J Pathol (1987) 1.58

Widespread p53 overexpression in human malignant tumors. An immunohistochemical study using methacarn-fixed, embedded tissue. Am J Pathol (1992) 1.57

Interferon-gamma and tumor necrosis factor synergize to induce nitric oxide production and inhibit mitochondrial respiration in vascular smooth muscle cells. Circ Res (1992) 1.56

Distribution of SPARC in normal and neoplastic human tissue. J Histochem Cytochem (1995) 1.55

Medical and surgical therapy in diverticular disease: a comparative study. Gastroenterology (1976) 1.53

Detection of stromal invasion in breast cancer: the myoepithelial markers. Adv Anat Pathol (2000) 1.52

Quantitative evaluation of HER-2/neu status in breast cancer by fluorescence in situ hybridization and by immunohistochemistry with image analysis. Am J Clin Pathol (2001) 1.51

Somatic mutations are frequent and increase with age in human kidney epithelial cells. Hum Mol Genet (1996) 1.50

Monoclonal antibodies to human intermediate filament proteins. III. Analysis of tumors. Am J Clin Pathol (1985) 1.50

Correlations between clinical variables and gene-expression profiles in carotid plaque instability. Eur J Vasc Endovasc Surg (2011) 1.50

Pravastatin and gemfibrozil alone and in combination for the treatment of hypercholesterolemia. Am J Med (1993) 1.50

Alpha-smooth muscle actin in parenchymal cells of bleomycin-injured rat lung. Lab Invest (1989) 1.50

Molecular cloning and functional expression of human connexin37, an endothelial cell gap junction protein. J Clin Invest (1993) 1.48

Routine pathologic parameters can predict Oncotype DX recurrence scores in subsets of ER positive patients: who does not always need testing? Breast Cancer Res Treat (2011) 1.47

Immunohistochemical detection of macrophages and T lymphocytes in atherosclerotic lesions of cholesterol-fed rabbits. Arterioscler Thromb (1991) 1.46

Enhanced expression of "muscle-specific" actin in glomerulonephritis. Kidney Int (1992) 1.46

Induction of B-type receptors for platelet-derived growth factor in vascular inflammation: possible implications for development of vascular proliferative lesions. Lancet (1988) 1.46

Complete chromogen separation and analysis in double immunohistochemical stains using Photoshop-based image analysis. J Histochem Cytochem (1999) 1.44

Cytoskeletal features of rat aortic cells during development. An electron microscopic, immunohistochemical, and biochemical study. Circ Res (1985) 1.43

Apoptosis of vascular smooth muscle cells induced by in vitro stimulation with interferon-gamma, tumor necrosis factor-alpha, and interleukin-1 beta. Arterioscler Thromb Vasc Biol (1996) 1.41

Mechanisms of arterial graft failure. 1. Role of cellular proliferation in early healing of PTFE prostheses. Am J Pathol (1985) 1.40

Anorectal complications of vaginal delivery. Dis Colon Rectum (1989) 1.40

Induction of tenascin in rat arterial injury. Relationship to altered smooth muscle cell phenotype. Am J Pathol (1991) 1.39

Colonic pericryptal fibroblasts. Differentiation pattern in embryogenesis and phenotypic modulation in epithelial proliferative lesions. Virchows Arch A Pathol Anat Histopathol (1989) 1.39

Alpha-smooth muscle actin is transiently expressed in embryonic rat cardiac and skeletal muscles. Differentiation (1988) 1.39

LDL immunization induces T-cell-dependent antibody formation and protection against atherosclerosis. Arterioscler Thromb Vasc Biol (2001) 1.39

Reduced frequency of memory CD8+ T lymphocytes in cerebrospinal fluid and blood of patients with multiple sclerosis. Autoimmunity (1995) 1.39

Assessment of proliferative activity in breast cancer: MIB-1 immunohistochemistry versus mitotic figure count. Hum Pathol (1999) 1.38

Cyclosporin A inhibits smooth muscle proliferation in the vascular response to injury. Proc Natl Acad Sci U S A (1988) 1.38

Rural EMS: making it work in Minnesota. Minn Med (1992) 1.38

Poorly differentiated synovial sarcoma: immunohistochemical distinction from primitive neuroectodermal tumors and high-grade malignant peripheral nerve sheath tumors. Am J Surg Pathol (1998) 1.38

Effects of sex and age on atherosclerosis and autoimmunity in apoE-deficient mice. Atherosclerosis (1999) 1.38

Renal angiomyolipoma: further immunophenotypic characterization of an expanding morphologic spectrum. Arch Pathol Lab Med (2001) 1.37

Transient immunomodulation with anti-CD40 ligand antibody and CTLA4Ig enhances persistence and secondary adenovirus-mediated gene transfer into mouse liver. Proc Natl Acad Sci U S A (1997) 1.35

Polyclonal origin of T lymphocytes in human atherosclerotic plaques. Lab Invest (1991) 1.35

Cytokeratin 8 immunostaining pattern and E-cadherin expression distinguish lobular from ductal breast carcinoma. Am J Clin Pathol (2000) 1.34

P504S immunohistochemical detection in 405 prostatic specimens including 376 18-gauge needle biopsies. Am J Surg Pathol (2002) 1.33

Cytodifferentiation and expression of alpha-smooth muscle actin mRNA and protein during primary culture of aortic smooth muscle cells. Correlation with cell density and proliferative state. Arteriosclerosis (1989) 1.32

Oligoclonal T cell expansions in atherosclerotic lesions of apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol (2000) 1.30

Atheroma: the artery wall and the environment. Int Rev Exp Pathol (1980) 1.30

Expression of platelet-derived growth factor B-chain and the platelet-derived growth factor receptor beta subunit in human breast tissue and breast carcinoma. Cancer Res (1995) 1.29

The immunophenotype of hemangiopericytomas and glomus tumors, with special reference to muscle protein expression: an immunohistochemical study and review of the literature. Mod Pathol (1991) 1.28

Myocardial infarction mediated by endothelin receptor signaling in hypercholesterolemic mice. Proc Natl Acad Sci U S A (1999) 1.28

Heterogeneity of myosin antigenic expression in vascular smooth muscle in vivo. Lab Invest (1984) 1.26

Association of apo B lipoproteins with arterial proteoglycans: pathological significance and molecular basis. Atherosclerosis (1998) 1.24

Generation of RCAS vectors useful for functional genomic analyses. DNA Res (2001) 1.23

Specific demonstration of myoepithelial cells by anti-alpha smooth muscle actin antibody. J Histochem Cytochem (1988) 1.22

Prelesional complement activation in experimental atherosclerosis. Terminal C5b-9 complement deposition coincides with cholesterol accumulation in the aortic intima of hypercholesterolemic rabbits. Lab Invest (1989) 1.21

Human atherosclerosis. IV. Immunocytochemical analysis of cell activation and proliferation in lesions of young adults. Am J Pathol (1993) 1.20

Intermediate filament proteins and actin isoforms as markers for soft tissue tumor differentiation and origin. I. Smooth muscle tumors. Am J Pathol (1987) 1.19