Published in J Cell Biol on October 01, 1992
Arp2/3 complex and actin depolymerizing factor/cofilin in dendritic organization and treadmilling of actin filament array in lamellipodia. J Cell Biol (1999) 8.24
Traction forces generated by locomoting keratocytes. J Cell Biol (1994) 4.97
Actomyosin-based retrograde flow of microtubules in the lamella of migrating epithelial cells influences microtubule dynamic instability and turnover and is associated with microtubule breakage and treadmilling. J Cell Biol (1997) 4.55
Visualizing infection of individual influenza viruses. Proc Natl Acad Sci U S A (2003) 4.10
Mechanical integration of actin and adhesion dynamics in cell migration. Annu Rev Cell Dev Biol (2010) 4.06
Identification of novel graded polarity actin filament bundles in locomoting heart fibroblasts: implications for the generation of motile force. J Cell Biol (1997) 3.25
Regulated actin cytoskeleton assembly at filopodium tips controls their extension and retraction. J Cell Biol (1999) 3.23
Actin filament organization in the fish keratocyte lamellipodium. J Cell Biol (1995) 3.20
The actin-based nanomachine at the leading edge of migrating cells. Biophys J (1999) 3.19
Regulation of actin dynamics in rapidly moving cells: a quantitative analysis. Biophys J (2002) 2.84
Visualization and molecular analysis of actin assembly in living cells. J Cell Biol (1998) 2.70
Slipping or gripping? Fluorescent speckle microscopy in fish keratocytes reveals two different mechanisms for generating a retrograde flow of actin. Mol Biol Cell (2004) 2.59
Role of cofilin in epidermal growth factor-stimulated actin polymerization and lamellipod protrusion. J Cell Biol (2000) 2.56
Cortical and cytoplasmic flow polarity in early embryonic cells of Caenorhabditis elegans. J Cell Biol (1993) 2.54
Comparative dynamics of retrograde actin flow and focal adhesions: formation of nascent adhesions triggers transition from fast to slow flow. PLoS One (2008) 2.11
Periodic patterns of actin turnover in lamellipodia and lamellae of migrating epithelial cells analyzed by quantitative Fluorescent Speckle Microscopy. Biophys J (2005) 2.11
Cytoskeletal remodeling during growth cone-target interactions. J Cell Biol (1993) 1.93
Cofilin promotes stimulus-induced lamellipodium formation by generating an abundant supply of actin monomers. J Cell Biol (2007) 1.93
Force transmission in migrating cells. J Cell Biol (2010) 1.89
Tracking retrograde flow in keratocytes: news from the front. Mol Biol Cell (2005) 1.88
Actin dynamics is essential for myosin-based transport of membrane organelles. Curr Biol (2008) 1.80
Simultaneous measurements of actin filament turnover, filament fraction, and monomer diffusion in endothelial cells. Biophys J (1998) 1.77
Moving and stationary actin filaments are involved in spreading of postmitotic PtK2 cells. J Cell Biol (1993) 1.75
Coordination of protrusion and translocation of the keratocyte involves rolling of the cell body. J Cell Biol (1996) 1.70
Isolation and characterization of a regulated form of actin depolymerizing factor. J Cell Biol (1993) 1.56
Control of neural crest cell behavior and migration: Insights from live imaging. Cell Adh Migr (2011) 1.51
Investigation of the mechanism of retraction of the cell margin and rearward flow of nodules during mitotic cell rounding. Mol Biol Cell (1997) 1.47
Cellular symmetry breaking during Caenorhabditis elegans development. Cold Spring Harb Perspect Biol (2009) 1.47
Accumulation of actin in subsets of pioneer growth cone filopodia in response to neural and epithelial guidance cues in situ. J Cell Biol (1993) 1.43
Slow local movements of collagen fibers by fibroblasts drive the rapid global self-organization of collagen gels. J Cell Biol (2002) 1.34
Fibroblasts and the ground they walk on. Physiology (Bethesda) (2013) 1.34
Rho-kinase and myosin II affect dynamic neural crest cell behaviors during epithelial to mesenchymal transition in vivo. Dev Biol (2008) 1.34
Interpreting photoactivated fluorescence microscopy measurements of steady-state actin dynamics. Biophys J (1995) 1.31
Cell crawling: first the motor, now the transmission. J Cell Biol (1998) 1.30
Focusing on unpolymerized actin. J Cell Biol (1993) 1.24
Role of focal adhesions and mechanical stresses in the formation and progression of the lamellipodium-lamellum interface [corrected]. Biophys J (2009) 1.14
Morphological control of inositol-1,4,5-trisphosphate-dependent signals. J Cell Biol (1999) 1.10
Oscillating activity of a Ca(2+)-sensitive K+ channel. A prerequisite for migration of transformed Madin-Darby canine kidney focus cells. J Clin Invest (1994) 1.10
Actin dynamics: from nanoscale to microscale. Annu Rev Biophys (2010) 1.09
Fluorescent actin analogs with a high affinity for profilin in vitro exhibit an enhanced gradient of assembly in living cells. J Cell Biol (1994) 1.07
Actin dynamics at the living cell submembrane imaged by total internal reflection fluorescence photobleaching. Biophys J (2000) 1.05
Actin dynamics affect mitochondrial quality control and aging in budding yeast. Curr Biol (2013) 1.03
A new dimension in retrograde flow: centripetal movement of engulfed particles. Biophys J (2001) 1.03
Regulation of the actin cycle in vivo by actin filament severing. Proc Natl Acad Sci U S A (2000) 1.01
Imaging of dynamic changes of the actin cytoskeleton in microextensions of live NIH3T3 cells with a GFP fusion of the F-actin binding domain of moesin. BMC Cell Biol (2000) 0.97
Intermediate filaments in motion: observations of intermediate filaments in cells using green fluorescent protein-vimentin. Mol Biol Cell (1999) 0.95
Polarization of actin cytoskeleton is reduced in dendritic protrusions during early spine development in hippocampal neuron. Mol Biol Cell (2012) 0.93
An analysis of actin delivery in the acrosomal process of thyone. Biophys J (1999) 0.91
Diffusion, capture and recycling of SCAR/WAVE and Arp2/3 complexes observed in cells by single-molecule imaging. J Cell Sci (2012) 0.90
New single-molecule speckle microscopy reveals modification of the retrograde actin flow by focal adhesions at nanometer scales. Mol Biol Cell (2014) 0.84
Structure and activation dynamics of RBL-2H3 cells observed with scanning force microscopy. Biophys J (1994) 0.81
Visualization of cytoskeletal dynamics in podocytes using adenoviral vectors. Cytoskeleton (Hoboken) (2014) 0.79
Competition and collaboration between different actin assembly pathways allows for homeostatic control of the actin cytoskeleton. Bioarchitecture (2015) 0.78
Analysis of actin FLAP dynamics in the leading lamella. PLoS One (2010) 0.76
Extending the molecular clutch beyond actin-based cell motility. New J Phys (2014) 0.76
Prediction of traction forces of motile cells. Interface Focus (2016) 0.76
Actin microfilament dynamics in locomoting cells. Nature (1991) 8.03
Rate constants for the reactions of ATP- and ADP-actin with the ends of actin filaments. J Cell Biol (1986) 7.79
Exchange of actin subunits at the leading edge of living fibroblasts: possible role of treadmilling. J Cell Biol (1985) 7.25
Actions of cytochalasins on the organization of actin filaments and microtubules in a neuronal growth cone. J Cell Biol (1988) 6.19
Polewards microtubule flux in the mitotic spindle: evidence from photoactivation of fluorescence. J Cell Biol (1989) 6.05
Cytoskeletal dynamics and nerve growth. Neuron (1988) 5.53
The locomotion of fibroblasts in culture. I. Movements of the leading edge. Exp Cell Res (1970) 4.91
Mobility of microinjected rhodamine actin within living chicken gizzard cells determined by fluorescence photobleaching recovery. Cell (1982) 4.87
Cortical flow in animal cells. Science (1988) 4.66
The locomotion of fibroblasts in culture. 3. Movements of particles on the dorsal surface of the leading lamella. Exp Cell Res (1970) 4.61
Control of actin polymerization in live and permeabilized fibroblasts. J Cell Biol (1991) 4.16
Directed lipid flow in cell membranes. Nature (1976) 3.19
The direction of membrane lipid flow in locomoting polymorphonuclear leukocytes. Science (1990) 2.58
Neuronal cytomechanics: the actin-based motility of growth cones. Science (1988) 2.44
Cell migration does not produce membrane flow. J Cell Biol (1990) 2.42
The physics of cell motility. J Cell Sci Suppl (1987) 2.13
The movements of fibrocytes. Exp Cell Res (1961) 1.96
Centripetal transport of cytoplasm, actin, and the cell surface in lamellipodia of fibroblasts. Cell Motil Cytoskeleton (1988) 1.96
Actin dynamics in growth cones. J Neurosci (1991) 1.72
Incorporation and turnover of biotin-labeled actin microinjected into fibroblastic cells: an immunoelectron microscopic study. J Cell Biol (1989) 1.70
Cell locomotion: new research tests old ideas on membrane and cytoskeletal flow. Cell Motil Cytoskeleton (1991) 1.64
Motion of particles adhering to the leading lamella of crawling cells. J Cell Biol (1981) 1.60
Subunit treadmilling of microtubules or actin in the presence of cellular barriers: possible conversion of chemical free energy into mechanical work. Proc Natl Acad Sci U S A (1982) 1.46
Probing the mechanism of incorporation of fluorescently labeled actin into stress fibers. J Cell Biol (1986) 1.41
Actin cytoskeleton of spread fibroblasts appears to assemble at the cell edges. J Cell Sci (1986) 1.40
Cytostructural dynamics of spreading and translocating cells. J Cell Biol (1982) 1.33
Leading edge movement and ultrastructure in mouse macrophages. J Struct Biol (1991) 1.23
Comparative behavior of membrane protein-antibody complexes on motile fibroblasts: implications for a mechanism of capping. J Cell Biol (1990) 1.07
Mapping trajectories of Pgp-1 membrane protein patches on surfaces of motile fibroblasts reveals a distinct boundary separating capping on the lamella and forward transport on the retracting tail. J Cell Sci (1991) 0.95
Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen. Science (1999) 12.52
Microtubule polymerization dynamics. Annu Rev Cell Dev Biol (1997) 12.39
Actin microfilament dynamics in locomoting cells. Nature (1991) 8.03
Mitotic spindle organization by a plus-end-directed microtubule motor. Nature (1992) 6.52
Kin I kinesins are microtubule-destabilizing enzymes. Cell (1999) 6.07
The rate of actin-based motility of intracellular Listeria monocytogenes equals the rate of actin polymerization. Nature (1992) 5.84
Probing spindle assembly mechanisms with monastrol, a small molecule inhibitor of the mitotic kinesin, Eg5. J Cell Biol (2000) 5.75
Actin polymerization is induced by Arp2/3 protein complex at the surface of Listeria monocytogenes. Nature (1997) 5.45
A heterodimeric coiled-coil protein required for mitotic chromosome condensation in vitro. Cell (1994) 5.43
XKCM1: a Xenopus kinesin-related protein that regulates microtubule dynamics during mitotic spindle assembly. Cell (1996) 5.21
Polewards chromosome movement driven by microtubule depolymerization in vitro. Nature (1988) 4.97
Real-time visualization of cell cycle-dependent changes in microtubule dynamics in cytoplasmic extracts. Cell (1990) 4.92
Interaction of human Arp2/3 complex and the Listeria monocytogenes ActA protein in actin filament nucleation. Science (1998) 4.74
The human Arp2/3 complex is composed of evolutionarily conserved subunits and is localized to cellular regions of dynamic actin filament assembly. J Cell Biol (1997) 4.34
Identification of a protein that interacts with tubulin dimers and increases the catastrophe rate of microtubules. Cell (1996) 4.32
The use of Xenopus egg extracts to study mitotic spindle assembly and function in vitro. Methods Cell Biol (1999) 4.31
Properties of the kinetochore in vitro. II. Microtubule capture and ATP-dependent translocation. J Cell Biol (1985) 4.21
Control of actin polymerization in live and permeabilized fibroblasts. J Cell Biol (1991) 4.16
Non-equilibration of hydrostatic pressure in blebbing cells. Nature (2005) 4.08
Role of GTP hydrolysis in microtubule dynamics: information from a slowly hydrolyzable analogue, GMPCPP. Mol Biol Cell (1992) 4.02
Two different microtubule-based motor activities with opposite polarities in kinetochores. Nature (1991) 3.93
Identification and partial characterization of mitotic centromere-associated kinesin, a kinesin-related protein that associates with centromeres during mitosis. J Cell Biol (1995) 3.73
Actin-dependent propulsion of endosomes and lysosomes by recruitment of N-WASP. J Cell Biol (2000) 3.71
Spatial control of actin polymerization during neutrophil chemotaxis. Nat Cell Biol (1999) 3.45
Mitotic spindle assembly by two different pathways in vitro. J Cell Biol (1991) 3.45
The bipolar kinesin, KLP61F, cross-links microtubules within interpolar microtubule bundles of Drosophila embryonic mitotic spindles. J Cell Biol (1999) 3.44
A model for the proposed roles of different microtubule-based motor proteins in establishing spindle bipolarity. Curr Biol (1998) 3.42
Involvement of profilin in the actin-based motility of L. monocytogenes in cells and in cell-free extracts. Cell (1994) 3.42
Identification of novel graded polarity actin filament bundles in locomoting heart fibroblasts: implications for the generation of motile force. J Cell Biol (1997) 3.25
The kinetochore microtubule minus-end disassembly associated with poleward flux produces a force that can do work. Mol Biol Cell (1996) 3.16
Microtubule-motor activity of a yeast centromere-binding protein complex. Nature (1992) 3.11
Localization of antigenic determinants in whole Drosophila embryos. Dev Biol (1983) 3.04
Myosin is involved in postmitotic cell spreading. J Cell Biol (1995) 3.03
Characterization of two related Drosophila gamma-tubulin complexes that differ in their ability to nucleate microtubules. J Cell Biol (1999) 2.88
Evidence for kinesin-related proteins in the mitotic apparatus using peptide antibodies. J Cell Sci (1992) 2.87
Behaviour of microtubules and actin filaments in living Drosophila embryos. Development (1988) 2.87
Mutations in the kinesin-like protein Eg5 disrupting localization to the mitotic spindle. Proc Natl Acad Sci U S A (1995) 2.82
Poleward microtubule flux mitotic spindles assembled in vitro. J Cell Biol (1991) 2.80
Polymerization of purified yeast septins: evidence that organized filament arrays may not be required for septin function. J Cell Biol (1998) 2.80
A small-molecule inhibitor of skeletal muscle myosin II. Nat Cell Biol (2002) 2.78
A purified Drosophila septin complex forms filaments and exhibits GTPase activity. J Cell Biol (1996) 2.76
Properties of the kinetochore in vitro. I. Microtubule nucleation and tubulin binding. J Cell Biol (1985) 2.75
Xenopus actin depolymerizing factor/cofilin (XAC) is responsible for the turnover of actin filaments in Listeria monocytogenes tails. J Cell Biol (1997) 2.66
Actin dynamics in vivo. Curr Opin Cell Biol (1997) 2.58
Functional analysis of a human homologue of the Drosophila actin binding protein anillin suggests a role in cytokinesis. J Cell Biol (2000) 2.57
Topoisomerase II does not play a scaffolding role in the organization of mitotic chromosomes assembled in Xenopus egg extracts. J Cell Biol (1993) 2.30
Eg5 is static in bipolar spindles relative to tubulin: evidence for a static spindle matrix. J Cell Biol (2001) 2.23
Anaphase A chromosome movement and poleward spindle microtubule flux occur At similar rates in Xenopus extract spindles. J Cell Biol (1998) 2.08
A new role for motor proteins as couplers to depolymerizing microtubules. J Cell Biol (1995) 2.06
Assembly properties of fluorescein-labeled tubulin in vitro before and after fluorescence bleaching. J Cell Biol (1984) 2.03
Colloid surface chemistry critically affects multiple particle tracking measurements of biomaterials. Biophys J (2004) 2.02
Isolation of mammalian centrosomes. Methods Enzymol (1986) 1.94
Kinesin-related proteins at mitotic spindle poles: function and regulation. Cell (1996) 1.84
The three faces of profilin. Cell (1993) 1.84
Moving and stationary actin filaments are involved in spreading of postmitotic PtK2 cells. J Cell Biol (1993) 1.75
XCTK2: a kinesin-related protein that promotes mitotic spindle assembly in Xenopus laevis egg extracts. J Cell Biol (1997) 1.71
Microtubule flux in mitosis is independent of chromosomes, centrosomes, and antiparallel microtubules. Mol Biol Cell (1994) 1.70
Phenotypic screening of small molecule libraries by high throughput cell imaging. Comb Chem High Throughput Screen (2003) 1.70
The SMC family: from chromosome condensation to dosage compensation. Curr Opin Cell Biol (1995) 1.68
Actin-dependent motile forces and cell motility. Curr Opin Cell Biol (1994) 1.67
Microtubule polymer assembly and transport during axonal elongation. J Cell Biol (1991) 1.58
Dissecting cellular processes using small molecules: identification of colchicine-like, taxol-like and other small molecules that perturb mitosis. Chem Biol (2000) 1.55
Cell cycle control of higher-order chromatin assembly around naked DNA in vitro. J Cell Biol (1991) 1.54
Investigation of the mechanism of retraction of the cell margin and rearward flow of nodules during mitotic cell rounding. Mol Biol Cell (1997) 1.47
Rappaport rules: cleavage furrow induction in animal cells. Proc Natl Acad Sci U S A (1997) 1.34
The nucleation-release model of actin filament dynamics in cell motility. Trends Cell Biol (1992) 1.29
Modulation of microtubule stability by kinetochores in vitro. J Cell Biol (1990) 1.28
Mechanical properties of Xenopus egg cytoplasmic extracts. Biophys J (2004) 1.22
A chemical inhibitor of N-WASP reveals a new mechanism for targeting protein interactions. Proc Natl Acad Sci U S A (2001) 1.22
Mitosis. Kinetochores pass the IQ test. Curr Biol (1994) 1.20
Actin, cofilin and cognition. Nature (1998) 1.14
The bulk of unpolymerized actin in Xenopus egg extracts is ATP-bound. Mol Biol Cell (1995) 1.12
Purification of cytoskeletal proteins using peptide antibodies. Methods Enzymol (1998) 1.11
Allele-specific activators and inhibitors for kinesin. Proc Natl Acad Sci U S A (1999) 1.10
A method that allows the assembly of kinetochore components onto chromosomes condensed in clarified Xenopus egg extracts. Proc Natl Acad Sci U S A (1997) 1.08
Regulation of the direction of chromosome movement. Cold Spring Harb Symp Quant Biol (1991) 1.06
Purification and assay of the platelet Arp2/3 complex. Methods Enzymol (1998) 0.95
Preparation and characterization of caged fluorescein tubulin. Methods Enzymol (1998) 0.95
Cell biology: powerful curves. Nature (2005) 0.94
Cell biology: How cilia beat. Nature (2010) 0.93
An assay for the activity of microtubule-based motors on the kinetochores of isolated Chinese hamster ovary chromosomes. Methods Cell Biol (1993) 0.88
Live imaging of the cytoskeleton in early cleavage-stage zebrafish embryos. Methods Cell Biol (2011) 0.86
Mitosis. The kinetochore in captivity. Nature (1990) 0.83
A GTPase controls cell-substrate adhesion in Xenopus XTC fibroblasts. J Cell Biol (1992) 0.82
Tubulin and FtsZ structures: functional and therapeutic implications. Bioessays (1998) 0.80
Purification and assay of a septin complex from Drosophila embryos. Methods Enzymol (1998) 0.80
Antigen processing: current issues, exceptional cases (Thy 1 alloantigen, MHC class-II-restricted cytolytic T cells), and implications for vaccine development. J Autoimmun (1989) 0.78
Dynamic confocal imaging of mitochondria in swimming Tetrahymena and of microtubule poleward flux in Xenopus extract spindles. Biol Bull (1999) 0.76
An efficient substitution reaction for the preparation of thyroid hormone analogues. Bioorg Med Chem (1998) 0.76
Cell motility: good things from slime. Nature (1987) 0.75