Published in Biophys J on September 01, 2002
Migration of tumor cells in 3D matrices is governed by matrix stiffness along with cell-matrix adhesion and proteolysis. Proc Natl Acad Sci U S A (2006) 7.48
The physics of filopodial protrusion. Biophys J (2005) 3.00
Emergence of large-scale cell morphology and movement from local actin filament growth dynamics. PLoS Biol (2007) 2.30
Ena/VASP proteins have an anti-capping independent function in filopodia formation. Mol Biol Cell (2007) 2.12
Periodic patterns of actin turnover in lamellipodia and lamellae of migrating epithelial cells analyzed by quantitative Fluorescent Speckle Microscopy. Biophys J (2005) 2.11
Spatio-temporal analysis of eukaryotic cell motility by improved force cytometry. Proc Natl Acad Sci U S A (2007) 2.11
The shape of motile cells. Curr Biol (2009) 2.00
Force generation by cytoskeletal filament end-tracking proteins. Biophys J (2004) 2.00
Tracking retrograde flow in keratocytes: news from the front. Mol Biol Cell (2005) 1.88
Growth velocities of branched actin networks. Biophys J (2003) 1.85
Mathematics of cell motility: have we got its number? J Math Biol (2008) 1.84
MULTISCALE TWO-DIMENSIONAL MODELING OF A MOTILE SIMPLE-SHAPED CELL. Multiscale Model Simul (2005) 1.83
Anomalous dynamics of cell migration. Proc Natl Acad Sci U S A (2008) 1.71
The forces behind cell movement. Int J Biol Sci (2007) 1.66
In silico reconstitution of actin-based symmetry breaking and motility. PLoS Biol (2009) 1.66
Phosphoinositides and Rho proteins spatially regulate actin polymerization to initiate and maintain directed movement in a one-dimensional model of a motile cell. Biophys J (2006) 1.58
Analysis of actin dynamics at the leading edge of crawling cells: implications for the shape of keratocyte lamellipodia. Eur Biophys J (2003) 1.52
Morphology of the lamellipodium and organization of actin filaments at the leading edge of crawling cells. Biophys J (2005) 1.50
Exploring the control circuit of cell migration by mathematical modeling. Biophys J (2008) 1.44
A mechanistic model of the actin cycle. Biophys J (2004) 1.36
Arp2 depletion inhibits sheet-like protrusions but not linear protrusions of fibroblasts and lymphocytes. Cell Motil Cytoskeleton (2008) 1.31
How cells integrate complex stimuli: the effect of feedback from phosphoinositides and cell shape on cell polarization and motility. PLoS Comput Biol (2012) 1.22
Pointed-end capping by tropomodulin3 negatively regulates endothelial cell motility. J Cell Biol (2003) 1.21
Direct observation of the uncapping of capping protein-capped actin filaments by CARMIL homology domain 3. J Biol Chem (2009) 1.21
Measurements of spatiotemporal changes in G-actin concentration reveal its effect on stimulus-induced actin assembly and lamellipodium extension. J Cell Biol (2011) 1.17
Excitable actin dynamics in lamellipodial protrusion and retraction. Biophys J (2012) 1.17
Actin filament curvature biases branching direction. Proc Natl Acad Sci U S A (2012) 1.17
Microfilament orientation constrains vesicle flow and spatial distribution in growing pollen tubes. Biophys J (2009) 1.13
Quantitative analysis of G-actin transport in motile cells. Biophys J (2008) 1.12
Spontaneous contractility-mediated cortical flow generates cell migration in three-dimensional environments. Biophys J (2011) 1.10
Cross-scale, cross-pathway evaluation using an agent-based non-small cell lung cancer model. Bioinformatics (2009) 1.10
Growing actin networks form lamellipodium and lamellum by self-assembly. Biophys J (2008) 1.10
Use of virtual cell in studies of cellular dynamics. Int Rev Cell Mol Biol (2010) 1.09
Actin dynamics: from nanoscale to microscale. Annu Rev Biophys (2010) 1.09
Active gels as a description of the actin-myosin cytoskeleton. HFSP J (2009) 1.09
Mathematical modeling of eukaryotic cell migration: insights beyond experiments. Annu Rev Cell Dev Biol (2013) 1.08
The effect of diffusion, depolymerization and nucleation promoting factors on actin gel growth. Eur Biophys J (2003) 1.08
Mathematical modelling and numerical simulation of the morphological development of neurons. BMC Neurosci (2006) 1.06
An open model of actin dendritic nucleation. Biophys J (2009) 1.05
Continuum model of cell adhesion and migration. J Math Biol (2008) 1.04
Depolymerization-driven flow in nematode spermatozoa relates crawling speed to size and shape. Biophys J (2008) 1.02
Mechanisms controlling cell size and shape during isotropic cell spreading. Biophys J (2010) 1.01
Membrane tension, myosin force, and actin turnover maintain actin treadmill in the nerve growth cone. Biophys J (2012) 1.01
The Moving Boundary Node Method: A level set-based, finite volume algorithm with applications to cell motility. J Comput Phys (2010) 1.01
Reaction-diffusion systems in intracellular molecular transport and control. Angew Chem Int Ed Engl (2010) 1.00
Redundant mechanisms for stable cell locomotion revealed by minimal models. Biophys J (2011) 0.99
A comparison of computational models for eukaryotic cell shape and motility. PLoS Comput Biol (2012) 0.97
Computational modeling of single-cell migration: the leading role of extracellular matrix fibers. Biophys J (2012) 0.97
Models for actin polymerization motors. J Math Biol (2008) 0.97
Attachment conditions control actin filament buckling and the production of forces. Biophys J (2007) 0.95
Myo1c facilitates G-actin transport to the leading edge of migrating endothelial cells. J Cell Biol (2012) 0.93
The key feature for early migratory processes: Dependence of adhesion, actin bundles, force generation and transmission on filopodia. Cell Adh Migr (2010) 0.92
Emergent complexity of the cytoskeleton: from single filaments to tissue. Adv Phys (2013) 0.92
Crowding effects on association reactions at membranes. Biophys J (2010) 0.91
A temporal model of cofilin regulation and the early peak of actin barbed ends in invasive tumor cells. Biophys J (2011) 0.90
Actin bundling: initiation mechanisms and kinetics. Phys Rev Lett (2008) 0.89
The effect of branching on the critical concentration and average filament length of actin. Biophys J (2005) 0.89
Bidirectional coupling between integrin-mediated signaling and actomyosin mechanics explains matrix-dependent intermittency of leading-edge motility. Mol Biol Cell (2013) 0.89
The Eps8/IRSp53/VASP network differentially controls actin capping and bundling in filopodia formation. PLoS Comput Biol (2011) 0.89
New proposed mechanism of actin-polymerization-driven motility. Biophys J (2008) 0.87
Mechano-chemical feedbacks regulate actin mesh growth in lamellipodial protrusions. Biophys J (2010) 0.87
Structural basis for capping protein sequestration by myotrophin (V-1). J Biol Chem (2010) 0.86
Signaling network triggers and membrane physical properties control the actin cytoskeleton-driven isotropic phase of cell spreading. Biophys J (2011) 0.85
Protrusive waves guide 3D cell migration along nanofibers. J Cell Biol (2015) 0.84
The effects of filament aging and annealing on a model lamellipodium undergoing disassembly by severing. Phys Biol (2010) 0.84
Physical model for membrane protrusions during spreading. Phys Biol (2008) 0.84
Modelling cellular signalling systems. Essays Biochem (2008) 0.84
Robust organizational principles of protrusive biopolymer networks in migrating living cells. PLoS One (2011) 0.83
Effect of capping protein on a growing filopodium. Biophys J (2010) 0.83
An experimental and computational study of the effect of ActA polarity on the speed of Listeria monocytogenes actin-based motility. PLoS Comput Biol (2009) 0.83
Distributed actin turnover in the lamellipodium and FRAP kinetics. Biophys J (2013) 0.83
Traveling wave solutions for a one-dimensional crawling nematode sperm cell model. J Math Biol (2004) 0.82
Geometrical and mechanical properties control actin filament organization. PLoS Comput Biol (2015) 0.82
Assembly and positioning of actomyosin rings by contractility and planar cell polarity. Elife (2015) 0.81
Modeling the synergy of cofilin and Arp2/3 in lamellipodial protrusive activity. Biophys J (2013) 0.81
MEDYAN: Mechanochemical Simulations of Contraction and Polarity Alignment in Actomyosin Networks. PLoS Comput Biol (2016) 0.81
A viscous two-phase model for contractile actomyosin bundles. J Math Biol (2013) 0.79
A phenomenological density-scaling approach to lamellipodial actin dynamics(†). Interface Focus (2014) 0.79
Damped and persistent oscillations in a simple model of cell crawling. J R Soc Interface (2011) 0.78
Migrating oligodendrocyte progenitor cells swell prior to soma dislocation. Sci Rep (2013) 0.78
Steric Effects Induce Geometric Remodeling of Actin Bundles in Filopodia. Biophys J (2016) 0.77
Actomyosin contraction, aggregation and traveling waves in a treadmilling actin array. Physica D (2016) 0.77
Protrusion of a Virtual Model Lamellipodium by Actin Polymerization: A Coarse-grained Langevin Dynamics Model. J Stat Phys (2008) 0.77
Modeling the formation of in vitro filopodia. J Math Biol (2010) 0.76
A microscopic formulation for the actin-driven motion of listeria in curved paths. Biophys J (2010) 0.76
Effects of molecular-scale processes on observable growth properties of actin networks. Phys Rev E Stat Nonlin Soft Matter Phys (2010) 0.76
When cell biology meets theory. J Cell Biol (2015) 0.76
Toward the structure of dynamic membrane-anchored actin networks: an approach using cryo-electron tomography. Cell Adh Migr (2007) 0.76
How capping protein enhances actin filament growth and nucleation on biomimetic beads. Phys Biol (2015) 0.75
Calcium-mediated actin reset (CaAR) mediates acute cell adaptations. Elife (2016) 0.75
A critical stress model for cell motility. Theor Biol Med Model (2012) 0.75
Simulation of lamellipodial fragments. J Math Biol (2011) 0.75
Network heterogeneity regulates steering in actin-based motility. Nat Commun (2017) 0.75
Actin-based cell motility and cell locomotion. Cell (1996) 10.30
Molecular mechanisms controlling actin filament dynamics in nonmuscle cells. Annu Rev Biophys Biomol Struct (2000) 10.11
The interaction of Arp2/3 complex with actin: nucleation, high affinity pointed end capping, and formation of branching networks of filaments. Proc Natl Acad Sci U S A (1998) 9.33
Reconstitution of actin-based motility of Listeria and Shigella using pure proteins. Nature (1999) 8.61
Arp2/3 complex and actin depolymerizing factor/cofilin in dendritic organization and treadmilling of actin filament array in lamellipodia. J Cell Biol (1999) 8.24
Actin microfilament dynamics in locomoting cells. Nature (1991) 8.03
Rate constants for the reactions of ATP- and ADP-actin with the ends of actin filaments. J Cell Biol (1986) 7.79
Cell motility driven by actin polymerization. Biophys J (1996) 7.29
Exchange of actin subunits at the leading edge of living fibroblasts: possible role of treadmilling. J Cell Biol (1985) 7.25
Analysis of the actin-myosin II system in fish epidermal keratocytes: mechanism of cell body translocation. J Cell Biol (1997) 6.67
Nascent focal adhesions are responsible for the generation of strong propulsive forces in migrating fibroblasts. J Cell Biol (2001) 6.32
Cellular motions and thermal fluctuations: the Brownian ratchet. Biophys J (1993) 5.99
Bioenergetics and kinetics of microtubule and actin filament assembly-disassembly. Int Rev Cytol (1982) 5.93
The rate of actin-based motility of intracellular Listeria monocytogenes equals the rate of actin polymerization. Nature (1992) 5.84
Scar, a WASp-related protein, activates nucleation of actin filaments by the Arp2/3 complex. Proc Natl Acad Sci U S A (1999) 5.62
Mechanism of actin-based motility. Science (2001) 5.04
Direct observation of dendritic actin filament networks nucleated by Arp2/3 complex and WASP/Scar proteins. Nature (2000) 4.73
Thrombin receptor ligation and activated Rac uncap actin filament barbed ends through phosphoinositide synthesis in permeabilized human platelets. Cell (1995) 4.39
How profilin promotes actin filament assembly in the presence of thymosin beta 4. Cell (1993) 4.20
Activation of the CDC42 effector N-WASP by the Shigella flexneri IcsA protein promotes actin nucleation by Arp2/3 complex and bacterial actin-based motility. J Cell Biol (1999) 4.20
Dynamics of capping protein and actin assembly in vitro: uncapping barbed ends by polyphosphoinositides. J Cell Biol (1996) 3.97
Influence of the C terminus of Wiskott-Aldrich syndrome protein (WASp) and the Arp2/3 complex on actin polymerization. Biochemistry (1999) 3.77
Membrane tether formation from blebbing cells. Biophys J (1999) 3.47
Deformation and flow of membrane into tethers extracted from neuronal growth cones. Biophys J (1996) 3.42
Dependence of locally measured cellular deformability on position on the cell, temperature, and cytochalasin B. Proc Natl Acad Sci U S A (1982) 3.38
Dimensional and mechanical dynamics of active and stable edges in motile fibroblasts investigated by using atomic force microscopy. Proc Natl Acad Sci U S A (1999) 3.33
Actin filament organization in the fish keratocyte lamellipodium. J Cell Biol (1995) 3.20
The actin-based nanomachine at the leading edge of migrating cells. Biophys J (1999) 3.19
Structure, subunit topology, and actin-binding activity of the Arp2/3 complex from Acanthamoeba. J Cell Biol (1997) 3.11
Comparison of actin and cell surface dynamics in motile fibroblasts. J Cell Biol (1992) 2.98
Sequences, structural models, and cellular localization of the actin-related proteins Arp2 and Arp3 from Acanthamoeba. J Cell Biol (1995) 2.77
Xenopus actin depolymerizing factor/cofilin (XAC) is responsible for the turnover of actin filaments in Listeria monocytogenes tails. J Cell Biol (1997) 2.66
Role of proteins of the Ena/VASP family in actin-based motility of Listeria monocytogenes. J Cell Biol (1999) 2.62
The Arp2/3 complex branches filament barbed ends: functional antagonism with capping proteins. Nat Cell Biol (2000) 2.46
Control of actin dynamics in cell motility. J Mol Biol (1997) 2.45
Actin polymerization and ATP hydrolysis. Science (1987) 2.42
Actin filaments elongate from their membrane-associated ends. J Cell Biol (1981) 2.40
Regulation of actin polymerization by Arp2/3 complex and WASp/Scar proteins. J Biol Chem (1999) 2.31
Actin-based movement of Listeria monocytogenes: actin assembly results from the local maintenance of uncapped filament barbed ends at the bacterium surface. J Cell Biol (1995) 2.27
Signaling to actin dynamics. J Cell Biol (1999) 2.26
Role of actin-filament disassembly in lamellipodium protrusion in motile cells revealed using the drug jasplakinolide. Curr Biol (1999) 2.21
An elastic analysis of Listeria monocytogenes propulsion. Biophys J (2000) 2.19
Membrane tension in swelling and shrinking molluscan neurons. J Neurosci (1998) 2.18
Separation of propulsive and adhesive traction stresses in locomoting keratocytes. J Cell Biol (1999) 2.16
Relationship between Arp2/3 complex and the barbed ends of actin filaments at the leading edge of carcinoma cells after epidermal growth factor stimulation. J Cell Biol (1999) 2.14
Secrets of actin-based motility revealed by a bacterial pathogen. Nat Rev Mol Cell Biol (2000) 2.12
New yeast actin-like gene required late in the cell cycle. Nature (1992) 2.12
Inhibition of the Arp2/3 complex-nucleated actin polymerization and branch formation by tropomyosin. Curr Biol (2001) 2.09
The Arp2/3 complex mediates actin polymerization induced by the small GTP-binding protein Cdc42. Proc Natl Acad Sci U S A (1998) 2.07
The Arp2/3 complex nucleates actin filament branches from the sides of pre-existing filaments. Nat Cell Biol (2001) 2.02
The composition and dynamics of cell-substratum adhesions in locomoting fish keratocytes. J Cell Sci (1997) 2.01
Regulating actin-filament dynamics in vivo. Trends Biochem Sci (2000) 1.97
GRB2 links signaling to actin assembly by enhancing interaction of neural Wiskott-Aldrich syndrome protein (N-WASp) with actin-related protein (ARP2/3) complex. J Biol Chem (2000) 1.97
Distinct roles of frontal and rear cell-substrate adhesions in fibroblast migration. Mol Biol Cell (2001) 1.93
Kinetic analysis of the interaction of actin-depolymerizing factor (ADF)/cofilin with G- and F-actins. Comparison of plant and human ADFs and effect of phosphorylation. J Biol Chem (1998) 1.85
How nematode sperm crawl. J Cell Sci (2002) 1.81
Membrane expansion increases endocytosis rate during mitosis. J Cell Biol (1999) 1.70
Control of actin dynamics in cell motility. Role of ADF/cofilin. J Biol Chem (1999) 1.66
The effects of Mg2+ at the high-affinity and low-affinity sites on the polymerization of actin and associated ATP hydrolysis. J Biol Chem (1986) 1.60
Self-organization of a propulsive actin network as an evolutionary process. Proc Natl Acad Sci U S A (2001) 1.60
Actin dynamics: assembly and disassembly of actin networks. Curr Biol (2001) 1.44
Chemotaxis in Dictyostelium. Annu Rev Physiol (1982) 1.43
Under physiological conditions actin disassembles slowly from the nonpreferred end of an actin filament. J Cell Biol (1983) 1.31
Acting like actin. The dynamics of the nematode major sperm protein (msp) cytoskeleton indicate a push-pull mechanism for amoeboid cell motility. J Cell Biol (2000) 1.27
Ciboulot regulates actin assembly during Drosophila brain metamorphosis. Cell (2000) 1.26
Cell motility: complex dynamics at the leading edge. Curr Biol (1997) 1.25
Local photorelease of caged thymosin beta4 in locomoting keratocytes causes cell turning. J Cell Biol (2001) 1.17
On the stall force for growing microtubules. Eur Biophys J (2000) 1.13
Signalling to actin: the Cdc42-N-WASP-Arp2/3 connection. Chem Biol (1999) 1.06
Control of actin filament length and turnover by actin depolymerizing factor (ADF/cofilin) in the presence of capping proteins and ARP2/3 complex. J Biol Chem (1999) 1.04
Gelsolin and ADF/cofilin enhance the actin dynamics of motile cells. Proc Natl Acad Sci U S A (2000) 1.03
Regulation of the actin cycle in vivo by actin filament severing. Proc Natl Acad Sci U S A (2000) 1.01
Gelsolin as a calcium-regulated actin filament-capping protein. Eur J Biochem (2000) 0.96
Distribution of F-actin elongation sites in lysed polymorphonuclear leukocytes parallels the distribution of endogenous F-actin. Cell Motil Cytoskeleton (1993) 0.96
Cdc42-induced actin filaments are protected from capping protein. Curr Biol (1999) 0.95
The deformability of BHK cells and polyoma virus-transformed BHK cells in relation to locomotory behaviour. J Cell Sci (1980) 0.83
How profilin/barbed-end synergy controls actin polymerization: a kinetic model of the ATP hydrolysis circuit. Cell Motil Cytoskeleton (1996) 0.80
Inferring individual rules from collective behavior. Proc Natl Acad Sci U S A (2010) 3.77
Polarization and movement of keratocytes: a multiscale modelling approach. Bull Math Biol (2006) 2.19
A comparison of mathematical models for polarization of single eukaryotic cells in response to guided cues. PLoS Comput Biol (2011) 2.00
Wave-pinning and cell polarity from a bistable reaction-diffusion system. Biophys J (2008) 1.86
Prevention of diabetes by manipulation of anti-IGRP autoimmunity: high efficiency of a low-affinity peptide. Nat Med (2005) 1.72
Phosphoinositides and Rho proteins spatially regulate actin polymerization to initiate and maintain directed movement in a one-dimensional model of a motile cell. Biophys J (2006) 1.58
Mathematical model for spatial segregation of the Rho-family GTPases based on inhibitory crosstalk. Bull Math Biol (2007) 1.46
How cells integrate complex stimuli: the effect of feedback from phosphoinositides and cell shape on cell polarization and motility. PLoS Comput Biol (2012) 1.22
Synthetic spatially graded Rac activation drives cell polarization and movement. Proc Natl Acad Sci U S A (2012) 1.14
ASYMPTOTIC AND BIFURCATION ANALYSIS OF WAVE-PINNING IN A REACTION-DIFFUSION MODEL FOR CELL POLARIZATION. SIAM J Appl Math (2011) 1.10
Role of social interactions in dynamic patterns of resource patches and forager aggregation. Proc Natl Acad Sci U S A (2012) 1.03
Modelling cell polarization driven by synthetic spatially graded Rac activation. PLoS Comput Biol (2012) 1.03
Actin filament branching and protrusion velocity in a simple 1D model of a motile cell. J Theor Biol (2006) 0.99
A quantitative comparison of rates of phagocytosis and digestion of apoptotic cells by macrophages from normal (BALB/c) and diabetes-prone (NOD) mice. J Appl Physiol (1985) (2007) 0.98
Inferring resource distributions from Atlantic bluefin tuna movements: an analysis based on net displacement and length of track. J Theor Biol (2006) 0.98
A comparison of computational models for eukaryotic cell shape and motility. PLoS Comput Biol (2012) 0.97
Quantifying macrophage defects in type 1 diabetes. J Theor Biol (2005) 0.92
Locust dynamics: behavioral phase change and swarming. PLoS Comput Biol (2012) 0.90
A temporal model of cofilin regulation and the early peak of actin barbed ends in invasive tumor cells. Biophys J (2011) 0.90
Deterministic versus stochastic cell polarisation through wave-pinning. Bull Math Biol (2012) 0.90
A conceptual model for milling formations in biological aggregates. Bull Math Biol (2008) 0.89
Pattern formation of Rho GTPases in single cell wound healing. Mol Biol Cell (2012) 0.87
A computational model of cell polarization and motility coupling mechanics and biochemistry. Multiscale Model Simul (2011) 0.86
Modelling the onset of Type 1 diabetes: can impaired macrophage phagocytosis make the difference between health and disease? Philos Trans A Math Phys Eng Sci (2006) 0.85
A model for intracellular actin waves explored by nonlinear local perturbation analysis. J Theor Biol (2013) 0.83
The role of low avidity T cells in the protection against type 1 diabetes: a modeling investigation. J Theor Biol (2008) 0.83
The pathogenicity of self-antigen decreases at high levels of autoantigenicity: a computational approach. Int Immunol (2010) 0.82
Modeling the synergy of cofilin and Arp2/3 in lamellipodial protrusive activity. Biophys J (2013) 0.81
Modeling effect of a γ-secretase inhibitor on amyloid-β dynamics reveals significant role of an amyloid clearance mechanism. Bull Math Biol (2010) 0.81
Chemotactic signaling, microglia, and Alzheimer's disease senile plaques: is there a connection? Bull Math Biol (2003) 0.81
On how monospecific memory-like autoregulatory CD8+ T cells can blunt diabetogenic autoimmunity: a computational approach. J Immunol (2010) 0.80
Analysis of a minimal Rho-GTPase circuit regulating cell shape. Phys Biol (2016) 0.79
Modeling competition among autoreactive CD8+ T cells in autoimmune diabetes: implications for antigen-specific therapy. Int Immunol (2006) 0.79
The effects of facilitation and competition on group foraging in patches. J Theor Biol (2012) 0.75