On the interaction of IgG subclasses with the low affinity Fc gamma RIIa (CD32) on human monocytes, neutrophils, and platelets. Analysis of a functional polymorphism to human IgG2.

PubWeight™: 2.04‹?› | Rank: Top 2%

🔗 View Article (PMC 443201)

Published in J Clin Invest on October 01, 1992

Authors

P W Parren1, P A Warmerdam, L C Boeije, J Arts, N A Westerdaal, A Vlug, P J Capel, L A Aarden, J G van de Winkel

Author Affiliations

1: Central Laboratory of the Netherlands Red Cross Blood Transfusion Service.

Articles citing this

A novel polymorphism of FcgammaRIIIa (CD16) alters receptor function and predisposes to autoimmune disease. J Clin Invest (1997) 2.48

Fc gamma RIIA alleles are heritable risk factors for lupus nephritis in African Americans. J Clin Invest (1996) 2.39

Activating and inhibitory IgG Fc receptors on human DCs mediate opposing functions. J Clin Invest (2005) 2.10

IgG subclasses and allotypes: from structure to effector functions. Front Immunol (2014) 1.95

Structural recognition and functional activation of FcgammaR by innate pentraxins. Nature (2008) 1.88

High immunoglobulin G2 (IgG2) and low IgG4 levels are associated with human resistance to Plasmodium falciparum malaria. Infect Immun (2000) 1.73

Effector function activities of a panel of mutants of a broadly neutralizing antibody against human immunodeficiency virus type 1. J Virol (2001) 1.64

Fcgamma receptor-mediated phagocytosis of Plasmodium falciparum-infected erythrocytes in vitro. Clin Exp Immunol (2002) 1.48

C-reactive protein binding to FcgammaRIIa on human monocytes and neutrophils is allele-specific. J Clin Invest (2000) 1.42

Role of neutrophil Fc gamma RIIa (CD32) and Fc gamma RIIIb (CD16) polymorphic forms in phagocytosis of human IgG1- and IgG3-opsonized bacteria and erythrocytes. Immunology (1994) 1.35

Utilization of immunoglobulin G Fc receptors by human immunodeficiency virus type 1: a specific role for antibodies against the membrane-proximal external region of gp41. J Virol (2009) 1.32

Human immunoglobulin G (IgG) Fc receptor IIA (CD32) polymorphism and IgG2-mediated bacterial phagocytosis by neutrophils. Infect Immun (1995) 1.24

Structural basis for Fc gammaRIIa recognition of human IgG and formation of inflammatory signaling complexes. J Immunol (2011) 1.23

Differences in Fcgamma receptor IIa genotypes and IgG subclass pattern of anti-malarial antibodies between sympatric ethnic groups in Mali. Malar J (2008) 1.13

Polymorphisms of TNF-enhancer and gene for FcgammaRIIa correlate with the severity of falciparum malaria in the ethnically diverse Indian population. Malar J (2008) 1.12

Use of allogeneic NK cells for cancer immunotherapy. Immunotherapy (2011) 1.11

Fcgamma receptors: structure, function and role as genetic risk factors in SLE. Genes Immun (2009) 1.10

Comparison among opsonic activity, antimeningococcal immunoglobulin G response, and serum bactericidal activity against meningococci in sera from vaccinees after immunization with a serogroup B outer membrane vesicle vaccine. Infect Immun (1995) 1.10

The lower serum immunoglobulin G2 level in severe cases than in mild cases of pandemic H1N1 2009 influenza is associated with cytokine dysregulation. Clin Vaccine Immunol (2010) 1.05

HLA class I antibodies trigger increased adherence of monocytes to endothelial cells by eliciting an increase in endothelial P-selectin and, depending on subclass, by engaging FcγRs. J Immunol (2013) 1.02

The exposure of autoantigens by microparticles underlies the formation of potent inflammatory components: the microparticle-associated immune complexes. EMBO Mol Med (2012) 1.01

Immunoglobulin G subclass response of juvenile periodontitis subjects to principal outer membrane proteins of Actinobacillus actinomycetemcomitans. Infect Immun (1995) 0.99

Evidence for non-random distribution of Fcgamma receptor genotype combinations. Immunogenetics (2003) 0.98

Contribution of Human FcγRs to Disease with Evidence from Human Polymorphisms and Transgenic Animal Studies. Front Immunol (2014) 0.98

FcgammaRIIa (CD32) polymorphism and anti-malarial IgG subclass pattern among Fulani and sympatric ethnic groups living in eastern Sudan. Malar J (2009) 0.97

Role of crosslinking for agonistic CD40 monoclonal antibodies as immune therapy of cancer. Cancer Immunol Res (2014) 0.97

Dynamics of the interaction of human IgG subtype immune complexes with cells expressing R and H allelic forms of a low-affinity Fc gamma receptor CD32A. J Immunol (2009) 0.96

Shifting FcγRIIA-ITAM from activation to inhibitory configuration ameliorates arthritis. J Clin Invest (2014) 0.95

Meningococcal disease and polymorphism of FcgammaRIIa (CD32) in late complement component-deficient individuals. Clin Exp Immunol (1998) 0.94

Fc γ receptor IIIB (FcγRIIIB) polymorphisms are associated with clinical malaria in Ghanaian children. PLoS One (2012) 0.94

Exploring the potential of monoclonal antibody therapeutics for HIV-1 eradication. AIDS Res Hum Retroviruses (2015) 0.94

Fcgamma receptor IIa, IIIa, and IIIb polymorphisms in German patients with systemic lupus erythematosus: association with clinical symptoms. Ann Rheum Dis (2002) 0.93

IgG2m4, an engineered antibody isotype with reduced Fc function. MAbs (2010) 0.93

Fc gamma receptor IIIb enhances Fc gamma receptor IIa function in an oxidant-dependent and allele-sensitive manner. J Clin Invest (1995) 0.92

Genetic polymorphisms associated with anti-malarial antibody levels in a low and unstable malaria transmission area in southern Sri Lanka. Malar J (2012) 0.92

No association between neutrophil FcgammaRIIa allelic polymorphism and anti-neutrophil cytoplasmic antibody (ANCA)-positive systemic vasculitis. Clin Exp Immunol (1999) 0.91

Immune complex processing in C1q-deficient mice. Clin Exp Immunol (2001) 0.90

Plasmodium falciparum merozoite surface protein 1 (MSP-1)-MSP-3 chimeric protein: immunogenicity determined with human-compatible adjuvants and induction of protective immune response. Infect Immun (2009) 0.89

Immunoglobulin subclass determines ability of immunoglobulin (Ig)G to capture and activate neutrophils presented as normal human IgG or disease-associated anti-neutrophil cytoplasm antibody (ANCA)-IgG. Clin Exp Immunol (2011) 0.87

Genetic diversity in human Fc receptor II for immunoglobulin G: Fc gamma receptor IIA ligand-binding polymorphism. Clin Diagn Lab Immunol (1994) 0.87

The Fcgamma receptor IIA-R/R131 genotype is associated with severe sepsis in community-acquired pneumonia. Clin Vaccine Immunol (2009) 0.87

Host immunity to Cryptococcus neoformans. Future Microbiol (2015) 0.85

A functional variant of Fcgamma receptor IIIA is associated with rheumatoid arthritis in individuals who are positive for anti-glucose-6-phosphate isomerase antibodies. Arthritis Res Ther (2005) 0.85

Relevance of immunoglobulin G Fc receptor polymorphism to recurrence of adult periodontitis in Japanese patients. Infect Immun (1997) 0.84

Increased proportion of responders to a murine anti-CD3 monoclonal antibody of the IgG1 class in patients with systemic lupus erythematosus (SLE). Clin Exp Immunol (1993) 0.84

Polymorphisms of CD16A and CD32 Fcγ receptors and circulating immune complexes in Ménière's disease: a case-control study. BMC Med Genet (2011) 0.83

Relevance of genetically determined host factors to the prognosis of meningococcal disease. Eur J Clin Microbiol Infect Dis (2004) 0.83

Evaluation of human FcgammaRIIA (CD32) and FcgammaRIIIB (CD16) polymorphisms in Caucasians and African-Americans using salivary DNA. Clin Diagn Lab Immunol (2000) 0.83

B cells in glomerulonephritis: focus on lupus nephritis. Semin Immunopathol (2007) 0.82

Tumor antigen-specific monoclonal antibodies and induction of T-cell immunity. Semin Oncol (2014) 0.80

Human FcR polymorphism and disease. Curr Top Microbiol Immunol (2014) 0.79

Clearance of red cells by monoclonal IgG3 anti-D in vivo is affected by the VF polymorphism of Fcgamma RIIIa (CD16). Clin Exp Immunol (2003) 0.79

Imprime PGG-Mediated Anti-Cancer Immune Activation Requires Immune Complex Formation. PLoS One (2016) 0.79

Lack of association of FcγRIIIb polymorphisms with systemic lupus erythematosus: a meta-analysis. Rheumatol Int (2010) 0.77

FCGR2A, FCGR3A polymorphisms and therapeutic efficacy of anti-EGFR monoclonal antibody in metastatic colorectal cancer. Oncotarget (2015) 0.77

The biological significance of evolution in autoimmune phenomena. Autoimmune Dis (2012) 0.77

Relevance of Fc gamma RIIIa-158V-F polymorphism to recurrence of adult periodontitis in Japanese patients. Clin Exp Immunol (1999) 0.77

Serum IgG2 concentration is associated with Gm-allotypes of IgG2 but not with the R131H polymorphism of human Fc-gamma receptor type IIa. J Clin Immunol (2002) 0.76

Could proteomic research deliver the next generation of treatments for pneumococcal meningitis? Interdiscip Perspect Infect Dis (2009) 0.76

Variability of the inhibition by total immunoglobulin of in vitro autoantibody-mediated erythrophagocytosis by mouse macrophages. Clin Exp Immunol (2006) 0.75

Association of Fc gamma-receptors IIa, IIIa, and IIIb genetic polymorphism with susceptibility to chronic periodontitis in South Indian population. Contemp Clin Dent (2015) 0.75

The impact of FcγRIIa and FcγRIIIa gene polymorphisms on responses to RCHOP chemotherapy in diffuse large B-cell lymphoma patients. Oncol Lett (2016) 0.75

FCGR2A and FCGR3A Genotypes in Human Immunodeficiency Virus Mother-to-Child Transmission. Open Forum Infect Dis (2015) 0.75

FCGRs Polymorphisms and Response to Trastuzumab in Patients With HER2-Positive Breast Cancer: Far From Predictive Value? World J Oncol (2015) 0.75

Male-specific association of the FCGR2A His167Arg polymorphism with Kawasaki disease. PLoS One (2017) 0.75

Articles cited by this

Production of hybridoma growth factor by human monocytes. Eur J Immunol (1987) 7.99

Fc receptors. Annu Rev Immunol (1991) 7.92

The T cell receptor/CD3 complex: a dynamic protein ensemble. Annu Rev Immunol (1988) 5.10

Comparison of the effector functions of human immunoglobulins using a matched set of chimeric antibodies. J Exp Med (1987) 3.82

Selective IgG subclass deficiency: quantification and clinical relevance. Clin Exp Immunol (1990) 3.20

Immune interferon induces the receptor for monomeric IgG1 on human monocytic and myeloid cells. J Exp Med (1983) 2.93

A single amino acid in the second Ig-like domain of the human Fc gamma receptor II is critical for human IgG2 binding. J Immunol (1991) 2.48

Biology of human immunoglobulin G Fc receptors. J Leukoc Biol (1991) 2.21

Function and heterogeneity of human Fc receptors for immunoglobulin G. J Clin Invest (1989) 2.04

Structure and expression of human IgG FcRII(CD32). Functional heterogeneity is encoded by the alternatively spliced products of multiple genes. J Exp Med (1989) 2.01

Serum IgG subclass concentrations in healthy adults: a study using monoclonal antisera. Clin Exp Immunol (1984) 1.99

Molecular basis for a polymorphism of human Fc gamma receptor II (CD32). J Exp Med (1990) 1.79

Monoclonal antibodies to human immune interferon and their use in a sensitive solid-phase ELISA. J Immunol Methods (1985) 1.62

Fc receptors for mouse IgG1 on human monocytes: polymorphism and role in antibody-induced T cell proliferation. J Immunol (1984) 1.59

Organization of the human and mouse low-affinity Fc gamma R genes: duplication and recombination. Science (1990) 1.55

Monitoring of platelet morphology during storage of platelet concentrates. Transfusion (1989) 1.47

Mechanisms by which accessory cells contribute in growth of resting T lymphocytes initiated by OKT3 antibody. Eur J Immunol (1985) 1.44

Monoclonal antibodies that bind to distinct epitopes on Fc gamma RI are able to trigger receptor function. J Immunol (1989) 1.41

An abnormality of the gene that encodes neutrophil Fc receptor III in a patient with systemic lupus erythematosus. J Clin Invest (1990) 1.41

Human IgG Fc receptor (hFcRII; CD32) exists as multiple isoforms in macrophages, lymphocytes and IgG-transporting placental epithelium. EMBO J (1989) 1.40

Fc gamma receptor III induces actin polymerization in human neutrophils and primes phagocytosis mediated by Fc gamma receptor II. J Immunol (1991) 1.38

Human IgG subclass pattern of inducing complement-mediated cytolysis depends on antigen concentration and to a lesser extent on epitope patchiness, antibody affinity and complement concentration. Eur J Immunol (1991) 1.36

Binding characteristics of dimeric IgG subclass complexes to human neutrophils. J Immunol (1989) 1.28

Induction of T cell proliferation with anti-CD3 switch-variant monoclonal antibodies: effects of heavy chain isotype in monocyte-dependent systems. Eur J Immunol (1987) 1.27

Molecular basis for a polymorphism involving Fc receptor II on human monocytes. J Immunol (1989) 1.27

Soluble Fc gamma receptor III in human plasma originates from release by neutrophils. J Clin Invest (1990) 1.27

A single amino acid distinguishes the high-responder from the low-responder form of Fc receptor II on human monocytes. Eur J Immunol (1991) 1.26

Biological activity of human-mouse IgG1, IgG2, IgG3, and IgG4 chimeric monoclonal antibodies with antitumor specificity. Proc Natl Acad Sci U S A (1988) 1.22

The monoclonal antibody 41H16 detects the Leu 4 responder form of human Fc gamma RII. J Immunol (1990) 1.19

Neutrophils express the high affinity receptor for IgG (Fc gamma RI, CD64) after in vivo application of recombinant human granulocyte colony-stimulating factor. Blood (1991) 1.10

Characterization of the IgG-Fc receptor on human platelets. Blood (1982) 1.09

Characterization of two Fc receptors for mouse immunoglobulins on human monocytes and cell lines. Scand J Immunol (1987) 1.02

Deficiency of glycosyl-phosphatidylinositol-linked membrane glycoproteins of leukocytes in paroxysmal nocturnal hemoglobinuria, description of a new diagnostic cytofluorometric assay. Blood (1990) 1.00

IgM anti-Fc gamma R autoantibodies trigger neutrophil degranulation. J Exp Med (1991) 0.96

Human Fc gamma receptors: stable inter-donor variation in quantitative expression on platelets correlates with functional responses. J Immunol (1987) 0.92

Binding of IgG containing immune complexes to human neutrophil Fc gamma RII and Fc gamma RIII induces actin polymerization by a pertussis toxin-insensitive transduction pathway. J Immunol (1991) 0.88

Selective modulation of two human monocyte Fc receptors for IgG by immobilized immune complexes. J Immunol (1988) 0.88

Characterization of IgG FcR-mediated proliferation of human T cells induced by mouse and human anti-CD3 monoclonal antibodies. Identification of a functional polymorphism to human IgG2 anti-CD3. J Immunol (1992) 0.87

Induction of intracellular Ca2+ mobilization and cytotoxicity by hybrid mouse monoclonal antibodies. Fc gamma RII regulation of Fc gamma RI-triggered functions or signaling? J Immunol (1991) 0.87

Fc-receptor for mouse IgG1 (Fc gamma RII) and antibody-mediated cell clearance in patients treated with Leu2a antibody. Transplantation (1989) 0.86

Induction of T-cell proliferation by recombinant mouse and chimeric mouse/human anti-CD3 monoclonal antibodies. Res Immunol (1992) 0.84

Preferential expression of human Fc gamma RIIIPMN (CD16) in paroxysmal nocturnal hemoglobinuria. Discordant expression of glycosyl phosphatidylinositol-linked proteins. J Clin Invest (1991) 0.82

Interleukin-6 enhances human Ig production, but not as a terminal differentiation factor for B lymphocytes. Res Immunol (1991) 0.79

Isolation of subclasses of human IgG with affinity chromatography. J Immunol Methods (1980) 0.79

Articles by these authors

Immunology of DNA. III. Crithidia luciliae, a simple substrate for the determination of anti-dsDNA with the immunofluorescence technique. Ann N Y Acad Sci (1975) 5.23

Increased plasma levels of interleukin-6 in sepsis. Blood (1989) 3.92

Functional discrimination between interleukin 6 and interleukin 1. Eur J Immunol (1988) 3.51

Human IgG Fc receptor heterogeneity: molecular aspects and clinical implications. Immunol Today (1993) 3.28

Polymorphism in mitogenic effect of IgG1 monoclonal antibodies against T3 antigen on human T cells. Nature (1983) 3.16

Prostaglandin-E2 is a potent inhibitor of human interleukin 12 production. J Exp Med (1995) 2.98

Impaired IgG-dependent anaphylaxis and Arthus reaction in Fc gamma RIII (CD16) deficient mice. Immunity (1996) 2.96

Molecular and quantitative analysis of helper T cell-replacing factors on the induction of antigen-sensitive B and T lymphocytes. J Immunol (1979) 2.79

Characteristics of a monoclonal antibody (WT-31) that recognizes a common epitope on the human T cell receptor for antigen. J Immunol (1985) 2.70

Interleukin 6 is involved in interleukin 1-induced activities. Eur J Immunol (1988) 2.63

Molecular cloning and nucleotide sequence of hog cholera virus strain Brescia and mapping of the genomic region encoding envelope protein E1. Virology (1990) 2.59

Molecular cloning and expression of hybridoma growth factor in Escherichia coli. J Immunol (1987) 2.59

Increased susceptibility to ultraviolet-B and carcinogens of mice lacking the DNA excision repair gene XPA. Nature (1995) 2.54

A single amino acid in the second Ig-like domain of the human Fc gamma receptor II is critical for human IgG2 binding. J Immunol (1991) 2.48

Serum levels of interleukin-6 and acute phase responses. Lancet (1987) 2.44

The Fc receptor gamma-chain and the tyrosine kinase Syk are essential for activation of mouse platelets by collagen. EMBO J (1997) 2.34

Experimental endotoxemia in humans: analysis of cytokine release and coagulation, fibrinolytic, and complement pathways. Blood (1990) 2.33

FcgammaRI (CD64) contributes substantially to severity of arthritis, hypersensitivity responses, and protection from bacterial infection. Immunity (2002) 2.31

Interleukin 6 (IL-6) in serum and urine of renal transplant recipients. Clin Exp Immunol (1988) 2.24

Anti-dsDNA and complement profiles as prognostic guides in systemic lupus erythematosus. Arthritis Rheum (1979) 2.23

Regulatory properties of LFA-1 alpha and beta chains in human T-lymphocyte activation. Nature (1988) 2.09

IgA and the IgA Fc receptor. Trends Immunol (2001) 2.05

Cross-reactivity of human and murine anti-DNA antibodies with heparan sulfate. The major glycosaminoglycan in glomerular basement membranes. J Clin Invest (1986) 2.00

The purification and quantitation of helper T cell-replacing factors secreted by murine spleen cells activated by concanavalin A. J Immunol (1979) 1.95

Activation of interleukin-2 gene transcription via the T-cell surface molecule CD28 is mediated through an NF-kB-like response element. J Biol Chem (1991) 1.92

Interleukin-8 in sepsis: relation to shock and inflammatory mediators. Infect Immun (1992) 1.85

Prevalence of acid reflux in functional dyspepsia and its association with symptom profile. Gut (2005) 1.82

Skewed distribution of IgG Fc receptor IIa (CD32) polymorphism is associated with renal disease in systemic lupus erythematosus patients. Arthritis Rheum (1995) 1.80

Cross-reactivity of anti-DNA antibodies with proteoglycans. Clin Exp Immunol (1984) 1.80

A growth-factor dependent B-cell hybridoma. Curr Top Microbiol Immunol (1986) 1.79

Molecular basis for a polymorphism of human Fc gamma receptor II (CD32). J Exp Med (1990) 1.79

The effect of interleukin-1, interleukin-6 and its interrelationship on the synthesis of serum amyloid A and C-reactive protein in primary cultures of adult human hepatocytes. Biochem Biophys Res Commun (1988) 1.76

An IL-13 promoter polymorphism associated with increased risk of allergic asthma. Genes Immun (1999) 1.75

Regulation of bioactive IL-12 production in lipopolysaccharide-stimulated human monocytes is determined by the expression of the p35 subunit. J Immunol (1996) 1.74

Modulation of adherence of coagulase-negative staphylococci to Teflon catheters in vitro. Eur J Clin Microbiol (1986) 1.73

Relationship between symptoms and ingestion of a meal in functional dyspepsia. Gut (2008) 1.67

Immunology of DNA. IV. Quantitative aspects of the Farr assay. J Immunol Methods (1976) 1.66

Effector function activities of a panel of mutants of a broadly neutralizing antibody against human immunodeficiency virus type 1. J Virol (2001) 1.64

Parathyroid hormone (PTH) and PTH-like protein (PLP) stimulate interleukin-6 production by osteogenic cells: a possible role of interleukin-6 in osteoclastogenesis. Biochem Biophys Res Commun (1989) 1.64

Immunology of DNA. I. The influence of reaction conditions on the Farr assay as used for the detection of anti-ds DNA. J Immunol Methods (1976) 1.63

Role of cytokines in sepsis. Adv Immunol (1997) 1.60

Fc receptors for mouse IgG1 on human monocytes: polymorphism and role in antibody-induced T cell proliferation. J Immunol (1984) 1.59

IgG receptor polymorphisms: risk factors for disease. Immunogenetics (1998) 1.59

Cocapping of the leukoadhesin molecules complement receptor type 3 and lymphocyte function-associated antigen-1 with Fc gamma receptor III on human neutrophils. Possible role of lectin-like interactions. J Immunol (1993) 1.55

Murine IgG1 complexes trigger immune effector functions predominantly via Fc gamma RIII (CD16). J Immunol (1998) 1.49

Clinical significance of IgG Fc receptors and Fc gamma R-directed immunotherapies. Immunol Today (1997) 1.48

Inflammation in autoimmunity: receptors for IgG revisited. Trends Immunol (2001) 1.41

Clinical immunology: a unified vision for Europe. Immunol Today (2000) 1.40

Tumor necrosis factor (TNF) inhibits interleukin (IL)-1 and/or IL-6 stimulated synthesis of C-reactive protein (CRP) and serum amyloid A (SAA) in primary cultures of human hepatocytes. Biochim Biophys Acta (1991) 1.38

Fc gamma receptor IIa (CD32) polymorphism in fulminant meningococcal septic shock in children. J Infect Dis (1994) 1.37

Prognostic value of anti-dsDNA in SLE. Ann Rheum Dis (1982) 1.35

Imaging and serum analysis of immune complex formation of radiolabelled infliximab and anti-infliximab in responders and non-responders to therapy for rheumatoid arthritis. Ann Rheum Dis (2006) 1.34

Signals involved in T cell activation. T cell proliferation induced through the synergistic action of anti-CD28 and anti-CD2 monoclonal antibodies. Eur J Immunol (1988) 1.34

Detection of antibodies to DNA by radioimmunoassay and immunofluorescence. Scand J Rheumatol Suppl (1975) 1.30

Phagocytosis of Staphylococcus aureus and Haemophilus influenzae type B opsonized with polyclonal human IgG1 and IgG2 antibodies. Functional hFc gamma RIIa polymorphism to IgG2. J Immunol (1993) 1.29

The binding of activated C3 to polysaccharides and immunoglobulins. J Immunol (1978) 1.29

Binding characteristics of dimeric IgG subclass complexes to human neutrophils. J Immunol (1989) 1.28

Induction of T cell proliferation with anti-CD3 switch-variant monoclonal antibodies: effects of heavy chain isotype in monocyte-dependent systems. Eur J Immunol (1987) 1.27

The quantification of human IgG subclasses in reference preparations. Clin Chim Acta (1985) 1.27

Evaluation of monoclonal antibodies having specificity for human IgG subclasses: results of the 2nd IUIS/WHO collaborative study. Immunol Lett (1992) 1.26

The p85 subunit of phosphatidylinositol 3-kinase associates with the Fc receptor gamma-chain and linker for activitor of T cells (LAT) in platelets stimulated by collagen and convulxin. J Biol Chem (1998) 1.25

Development of a human interleukin-6 receptor antagonist. J Biol Chem (1994) 1.25

Fc gamma receptor IIa (CD32) heterogeneity in patients with recurrent bacterial respiratory tract infections. J Infect Dis (1994) 1.25

Structure-function analysis of human IL-6. Epitope mapping of neutralizing monoclonal antibodies with amino- and carboxyl-terminal deletion mutants. J Immunol (1990) 1.25

Induction of immunoglobulin synthesis by interleukin 2 is T4+/T8- cell dependent. A role for interleukin 2 in the pokeweed mitogen-driven system. Eur J Immunol (1985) 1.24

Human immunoglobulin G (IgG) Fc receptor IIA (CD32) polymorphism and IgG2-mediated bacterial phagocytosis by neutrophils. Infect Immun (1995) 1.24

IL-6 is an intermediate in IL-1-induced thymocyte proliferation. J Immunol (1989) 1.23

Functional association between the human myeloid immunoglobulin A Fc receptor (CD89) and FcR gamma chain. Molecular basis for CD89/FcR gamma chain association. J Biol Chem (1995) 1.23

Antigen targeting to myeloid-specific human Fc gamma RI/CD64 triggers enhanced antibody responses in transgenic mice. J Clin Invest (1996) 1.23

Interleukin-6 (IL-6) in synovial fluid and serum of patients with rheumatic diseases. Scand J Rheumatol (1988) 1.22

Histone and DNA detection in swollen spermatozoa and somatic cells, by immunofluorescence. Clin Exp Immunol (1976) 1.21

Detection of anti-dsDNA as diagnostic tool. Ann Rheum Dis (1981) 1.21

Inhibition of cytokine production by methotrexate. Studies in healthy volunteers and patients with rheumatoid arthritis. Rheumatology (Oxford) (2003) 1.20

Reduced production of IL-12 and IL-12-dependent IFN-gamma release in patients with allergic asthma. J Immunol (1997) 1.20

Histamine inhibits the production of interleukin-12 through interaction with H2 receptors. J Clin Invest (1998) 1.20

FcalphaRI-positive liver Kupffer cells: reappraisal of the function of immunoglobulin A in immunity. Nat Med (2000) 1.19

Immunoglobulin A-mediated protection against Bordetella pertussis infection. Infect Immun (2001) 1.19

Characterization of an interleukin-6-mediated autocrine growth loop in the human multiple myeloma cell line, U266. Blood (1991) 1.19

Mac-1 (CD11b/CD18) is essential for Fc receptor-mediated neutrophil cytotoxicity and immunologic synapse formation. Blood (2001) 1.18

Induction of nonspecific cytotoxicity by monoclonal anti-T3 antibodies. J Immunol (1985) 1.18

Activation of toll-like receptors 2 and 4 by gram-negative periodontal bacteria. Oral Microbiol Immunol (2007) 1.18

Effects on leukocytes after injection of tumor necrosis factor into healthy humans. Blood (1992) 1.17

Functional analysis of human Fc gamma RII (CD32) isoforms expressed in B lymphocytes. J Immunol (1994) 1.17

Therapeutic efficacy of intravenous immunoglobulin preparations depends on the immunoglobulin G dimers: studies in experimental immune thrombocytopenia. Blood (2001) 1.17