Interleukin 6 is involved in interleukin 1-induced activities.

PubWeight™: 2.63‹?› | Rank: Top 1%

🔗 View Article (PMID 3260188)

Published in Eur J Immunol on June 01, 1988

Authors

M Helle1, J P Brakenhoff, E R De Groot, L A Aarden

Author Affiliations

1: Central Laboratory, The Netherlands Red Cross Blood Transfusion Service, Amsterdam.

Articles citing this

Interleukin 10(IL-10) inhibits cytokine synthesis by human monocytes: an autoregulatory role of IL-10 produced by monocytes. J Exp Med (1991) 16.81

Interleukin-6 and the acute phase response. Biochem J (1990) 7.97

The effect of novel polymorphisms in the interleukin-6 (IL-6) gene on IL-6 transcription and plasma IL-6 levels, and an association with systemic-onset juvenile chronic arthritis. J Clin Invest (1998) 6.76

Activation of interleukin-6 gene expression through the NF-kappa B transcription factor. Mol Cell Biol (1990) 6.57

Interleukin-6 response of epithelial cell lines to bacterial stimulation in vitro. Infect Immun (1992) 2.82

Arterial inflammation in mice lacking the interleukin 1 receptor antagonist gene. J Exp Med (2000) 2.50

Interleukin-6 in the injured patient. Marker of injury or mediator of inflammation? Ann Surg (1996) 2.24

Interleukin-6 response to deliberate colonization of the human urinary tract with gram-negative bacteria. Infect Immun (1991) 2.22

Interleukin-6 induced at mucosal surfaces by gram-negative bacterial infection. Infect Immun (1989) 2.13

Interleukin 6 influences germinal center development and antibody production via a contribution of C3 complement component. J Exp Med (1998) 1.78

Acute-phase reaction induces a specific complex between hepatic nuclear proteins and the interleukin 6 response element of the rat alpha 2-macroglobulin gene. Proc Natl Acad Sci U S A (1990) 1.66

Synergistic action of interleukin-6 and glucocorticoids is mediated by the interleukin-6 response element of the rat alpha 2 macroglobulin gene. Mol Cell Biol (1992) 1.46

Uroepithelial cells are part of a mucosal cytokine network. Infect Immun (1994) 1.24

Tumor necrosis factor and interleukin-6 in Candida albicans infection in normal and granulocytopenic mice. Infect Immun (1992) 1.22

Effects of anti-inflammatory agents on mucosal inflammation induced by infection with gram-negative bacteria. Infect Immun (1990) 1.14

Bronchial inflammation in chronic bronchitis assessed by measurement of cell products in bronchial lavage fluid. Thorax (1995) 1.14

Release of vasoactive cytokines by antibody-enhanced dengue virus infection of a human mast cell/basophil line. J Virol (2000) 1.13

Elevated plasma interleukin-6 and increased severity and mortality in alcoholic hepatitis. Clin Exp Immunol (1991) 1.05

Interleukin-6 and ACTH act synergistically to stimulate the release of corticosterone from adrenal gland cells. Clin Exp Immunol (1990) 1.02

The role of C5a in interleukin-6 production induced by lipopolysaccharide or interleukin-1. Immunology (1991) 0.97

Neuromodulative actions of cytokines. Yale J Biol Med (1990) 0.95

Leucocytosis induced in rabbits by intravenous or central injection of granulocyte colony stimulating factor. J Physiol (1990) 0.94

Production of IL-6 by T cells from the femoral head of patients with rapidly destructive coxopathy (RDC). Clin Exp Immunol (1996) 0.91

Opium addiction increases interleukin 1 receptor antagonist (IL-1Ra) in the coronary artery disease patients. PLoS One (2012) 0.91

Somnogenic cytokines and models concerning their effects on sleep. Yale J Biol Med (1990) 0.89

Lipopolysaccharide-induced biliary factors enhance invasion of Salmonella enteritidis in a rat model. Infect Immun (2000) 0.88

(-)-Epigallocatechin gallate reduces platelet-derived growth factor-BB-stimulated interleukin-6 synthesis in osteoblasts: suppression of SAPK/JNK. Mediators Inflamm (2009) 0.88

Human interleukin-1 induces a rapid relaxation of the rabbit isolated mesenteric artery. Br J Pharmacol (1991) 0.87

Interleukin 6 is autoregulated by transcriptional mechanisms in cultures of rat osteoblastic cells. J Clin Invest (1997) 0.87

Production and modulation of interleukin 6 synthesis by synoviocytes derived from patients with arthritic disease. Ann Rheum Dis (1992) 0.86

Epithelial glucosphingolipid expression as a determinant of bacterial adherence and cytokine production. Infect Immun (1994) 0.84

Endogenous cannabinoids induce fever through the activation of CB1 receptors. Br J Pharmacol (2009) 0.83

Functional and structural differences in febrile mechanism between rabbits and rats. J Physiol (1990) 0.83

Islet inflammation and hyperplasia induced by the pancreatic islet-specific overexpression of interleukin-6 in transgenic mice. Am J Pathol (1994) 0.82

Role of acute-phase proteins in interleukin-1-induced nonspecific resistance to bacterial infections in mice. Antimicrob Agents Chemother (1993) 0.81

p-Cymene modulates in vitro and in vivo cytokine production by inhibiting MAPK and NF-κB activation. Inflammation (2013) 0.81

Ciliary neurotrophic factor is an endogenous pyrogen. Proc Natl Acad Sci U S A (1993) 0.81

Affinity-purified soluble Fc epsilon RII/CD23 derived from a culture supernatant of an EBV-immortalized B-cell line induced a monophasic fever in rabbits. Immunology (1991) 0.80

Unresponsiveness of CD4-8+/- thymocytes to lectin stimulation in LEC mutant rats. Immunology (1998) 0.80

Effects of physical training on febrile and acute-phase responses induced in rats by bacterial endotoxin or interleukin-1. J Physiol (1990) 0.80

The selective antigen-presenting cell capacity of activated B lymphocytes in HLA-II-restricted responses of CD4+ T lymphocytes. Immunology (1989) 0.79

Production of interleukin-1 by draining lymph node cells during the induction phase of contact sensitization in mice. Immunology (1990) 0.79

Febrile response induced by cecal ligation and puncture (CLP) in rats: involvement of prostaglandin E2 and cytokines. Med Microbiol Immunol (2011) 0.78

Interactions between rnacrophage cytokines and eicosanoids in expression of antitumour activity. Mediators Inflamm (1992) 0.77

Expression of interleukin-1 alpha, interleukin-1 beta and interleukin-6 in chronic B lymphocytic leukaemia (B-CLL) cells from patients at different stages of disease progression. Clin Exp Immunol (1991) 0.76

Conditioned medium from concanavalin A-stimulated spleen cells inhibits the IgE-dependent sensitization of murine peritoneal mast cells in vitro. Immunology (1990) 0.75

Effects of low and standard intra-abdominal pressure on systemic inflammation and immune response in laparoscopic adrenalectomy: A prospective randomised study. J Minim Access Surg (2016) 0.75

Articles by these authors

Production of hybridoma growth factor by human monocytes. Eur J Immunol (1987) 7.99

Major transcript of the frameshifted coxII gene from trypanosome mitochondria contains four nucleotides that are not encoded in the DNA. Cell (1986) 5.49

Immunology of DNA. III. Crithidia luciliae, a simple substrate for the determination of anti-dsDNA with the immunofluorescence technique. Ann N Y Acad Sci (1975) 5.23

Increased plasma levels of interleukin-6 in sepsis. Blood (1989) 3.92

Functional discrimination between interleukin 6 and interleukin 1. Eur J Immunol (1988) 3.51

Prostaglandin-E2 is a potent inhibitor of human interleukin 12 production. J Exp Med (1995) 2.98

Molecular and quantitative analysis of helper T cell-replacing factors on the induction of antigen-sensitive B and T lymphocytes. J Immunol (1979) 2.79

Molecular cloning and expression of hybridoma growth factor in Escherichia coli. J Immunol (1987) 2.59

I. A bioactive designer cytokine for human hematopoietic progenitor cell expansion. Nat Biotechnol (1997) 2.47

Serum levels of interleukin-6 and acute phase responses. Lancet (1987) 2.44

Experimental endotoxemia in humans: analysis of cytokine release and coagulation, fibrinolytic, and complement pathways. Blood (1990) 2.33

FcgammaRI (CD64) contributes substantially to severity of arthritis, hypersensitivity responses, and protection from bacterial infection. Immunity (2002) 2.31

Interleukin 6 (IL-6) in serum and urine of renal transplant recipients. Clin Exp Immunol (1988) 2.24

Anti-dsDNA and complement profiles as prognostic guides in systemic lupus erythematosus. Arthritis Rheum (1979) 2.23

Regulatory properties of LFA-1 alpha and beta chains in human T-lymphocyte activation. Nature (1988) 2.09

On the interaction of IgG subclasses with the low affinity Fc gamma RIIa (CD32) on human monocytes, neutrophils, and platelets. Analysis of a functional polymorphism to human IgG2. J Clin Invest (1992) 2.04

The purification and quantitation of helper T cell-replacing factors secreted by murine spleen cells activated by concanavalin A. J Immunol (1979) 1.95

Activation of interleukin-2 gene transcription via the T-cell surface molecule CD28 is mediated through an NF-kB-like response element. J Biol Chem (1991) 1.92

Interleukin-8 in sepsis: relation to shock and inflammatory mediators. Infect Immun (1992) 1.85

A growth-factor dependent B-cell hybridoma. Curr Top Microbiol Immunol (1986) 1.79

The effect of interleukin-1, interleukin-6 and its interrelationship on the synthesis of serum amyloid A and C-reactive protein in primary cultures of adult human hepatocytes. Biochem Biophys Res Commun (1988) 1.76

An IL-13 promoter polymorphism associated with increased risk of allergic asthma. Genes Immun (1999) 1.75

Regulation of bioactive IL-12 production in lipopolysaccharide-stimulated human monocytes is determined by the expression of the p35 subunit. J Immunol (1996) 1.74

Immunology of DNA. IV. Quantitative aspects of the Farr assay. J Immunol Methods (1976) 1.66

Parathyroid hormone (PTH) and PTH-like protein (PLP) stimulate interleukin-6 production by osteogenic cells: a possible role of interleukin-6 in osteoclastogenesis. Biochem Biophys Res Commun (1989) 1.64

Immunology of DNA. I. The influence of reaction conditions on the Farr assay as used for the detection of anti-ds DNA. J Immunol Methods (1976) 1.63

Role of cytokines in sepsis. Adv Immunol (1997) 1.60

Tumor necrosis factor (TNF) inhibits interleukin (IL)-1 and/or IL-6 stimulated synthesis of C-reactive protein (CRP) and serum amyloid A (SAA) in primary cultures of human hepatocytes. Biochim Biophys Acta (1991) 1.38

Prognostic value of anti-dsDNA in SLE. Ann Rheum Dis (1982) 1.35

Signals involved in T cell activation. T cell proliferation induced through the synergistic action of anti-CD28 and anti-CD2 monoclonal antibodies. Eur J Immunol (1988) 1.34

Imaging and serum analysis of immune complex formation of radiolabelled infliximab and anti-infliximab in responders and non-responders to therapy for rheumatoid arthritis. Ann Rheum Dis (2006) 1.34

Production and characterization of monoclonal antibodies raised against recombinant human granzymes A and B and showing cross reactions with the natural proteins. J Immunol Methods (1993) 1.33

Detection of antibodies to DNA by radioimmunoassay and immunofluorescence. Scand J Rheumatol Suppl (1975) 1.30

Induction of T cell proliferation with anti-CD3 switch-variant monoclonal antibodies: effects of heavy chain isotype in monocyte-dependent systems. Eur J Immunol (1987) 1.27

Development of a human interleukin-6 receptor antagonist. J Biol Chem (1994) 1.25

Structure-function analysis of human IL-6. Epitope mapping of neutralizing monoclonal antibodies with amino- and carboxyl-terminal deletion mutants. J Immunol (1990) 1.25

Induction of immunoglobulin synthesis by interleukin 2 is T4+/T8- cell dependent. A role for interleukin 2 in the pokeweed mitogen-driven system. Eur J Immunol (1985) 1.24

IL-6 is an intermediate in IL-1-induced thymocyte proliferation. J Immunol (1989) 1.23

Interleukin-6 (IL-6) in synovial fluid and serum of patients with rheumatic diseases. Scand J Rheumatol (1988) 1.22

Histone and DNA detection in swollen spermatozoa and somatic cells, by immunofluorescence. Clin Exp Immunol (1976) 1.21

Detection of anti-dsDNA as diagnostic tool. Ann Rheum Dis (1981) 1.21

Inhibition of cytokine production by methotrexate. Studies in healthy volunteers and patients with rheumatoid arthritis. Rheumatology (Oxford) (2003) 1.20

Reduced production of IL-12 and IL-12-dependent IFN-gamma release in patients with allergic asthma. J Immunol (1997) 1.20

Histamine inhibits the production of interleukin-12 through interaction with H2 receptors. J Clin Invest (1998) 1.20

Characterization of an interleukin-6-mediated autocrine growth loop in the human multiple myeloma cell line, U266. Blood (1991) 1.19

Structure-function analysis of interleukin-6 utilizing human/murine chimeric molecules. Involvement of two separate domains in receptor binding. J Biol Chem (1993) 1.18

Activation of toll-like receptors 2 and 4 by gram-negative periodontal bacteria. Oral Microbiol Immunol (2007) 1.18

Effects on leukocytes after injection of tumor necrosis factor into healthy humans. Blood (1992) 1.17

Induction of urinary interleukin-1 (IL-1), IL-2, IL-6, and tumour necrosis factor during intravesical immunotherapy with bacillus Calmette-Guérin in superficial bladder cancer. Cancer Immunol Immunother (1992) 1.15

Immobilized anti-CD3 monoclonal antibodies induce accessory cell-independent lymphokine production, proliferation and helper activity in human T lymphocytes. Immunology (1989) 1.15

Interleukin-6 and its relation to the humoral immune response and clinical parameters in burned patients. Surgery (1991) 1.14

Chromatin-independent binding of serum amyloid P component to apoptotic cells. J Immunol (2001) 1.14

Interleukin-6 mediates host defense responses induced by abdominal surgery. Surgery (1993) 1.13

Release of interleukin-12 in experimental Escherichia coli septic shock in baboons: relation to plasma levels of interleukin-10 and interferon-gamma. Blood (1996) 1.12

Time between onset of apoptosis and release of nucleosomes from apoptotic cells: putative implications for systemic lupus erythematosus. Ann Rheum Dis (2003) 1.11

Human acid alpha-glucosidase from rabbit milk has therapeutic effect in mice with glycogen storage disease type II. Hum Mol Genet (1999) 1.10

A possible autocrine role for interleukin-6 in two lymphoma cell lines. Blood (1989) 1.09

Identification of two novel regions of human IL-6 responsible for receptor binding and signal transduction. J Immunol (1994) 1.09

Functional polymorphisms of Fc receptors in human monocyte-mediated cytotoxicity towards erythrocytes induced by murine isotype switch variants. J Immunol (1989) 1.08

Dissociation of DNA/anti-DNA complexes at high pH. Immunol Commun (1980) 1.07

High IL-13 production by human neonatal T cells: neonate immune system regulator? Eur J Immunol (2001) 1.07

Immunogenicity does not influence treatment with etanercept in patients with ankylosing spondylitis. Ann Rheum Dis (2008) 1.05

Chimaeric anti-interleukin 6 monoclonal antibodies in the treatment of advanced multiple myeloma: a phase I dose-escalating study. Br J Haematol (1998) 1.05

Decreased clinical response to adalimumab in ankylosing spondylitis is associated with antibody formation. Ann Rheum Dis (2009) 1.04

The first international standard for antibodies to double stranded DNA. Ann Rheum Dis (1988) 1.01

Analysis of human IL-6 mutants expressed in Escherichia coli. Biologic activities are not affected by deletion of amino acids 1-28. J Immunol (1989) 1.01

Clusterin: a protective mediator for ischemic cardiomyocytes? Am J Physiol Heart Circ Physiol (2005) 1.00

Endogenous interleukin 6 production in multiple myeloma patients treated with chimeric monoclonal anti-IL6 antibodies indicates the existence of a positive feed-back loop. J Clin Invest (1996) 1.00

Inefficacy of infliximab in ankylosing spondylitis is correlated with antibody formation. Ann Rheum Dis (2007) 0.99

Development of an interleukin (IL) 6 receptor antagonist that inhibits IL-6-dependent growth of human myeloma cells. J Exp Med (1994) 0.99

The relation among stress, adrenalin, interleukin 6 and acute phase proteins in the rat. Clin Immunol Immunopathol (1990) 0.99

Murine monoclonal isotype switch variants. Detection with rat monoclonal antibodies in ELISA and isolation by sequential sublining. J Immunol Methods (1988) 0.99

Cytokine production in whole blood cell cultures of patients with rheumatoid arthritis. Ann Rheum Dis (1997) 0.98

T cell triggering by lectins. I. Requirements for interleukin 2 production; lectin concentration determines the accessory cell dependency. Eur J Immunol (1985) 0.97

Interleukin-6 (IL-6) and acute phase proteins in the disease course of patients with systemic lupus erythematosus. Rheumatol Int (1989) 0.96

Immunology of DNA. VI. The effect of mercaptans on IgG and IgM anti-dsDNA. J Immunol Methods (1977) 0.96

Soluble human interleukin-6 receptor. Expression in insect cells, purification and characterization. Eur J Biochem (1995) 0.96

Involvement of the Arg179 in the active site of human IL-6. Eur J Biochem (1993) 0.96

T cell triggering by lectins. II. Stimuli for induction of interleukin 2 responsiveness and interleukin 2 production differ only in quantitative aspects. Eur J Immunol (1985) 0.96

Mannan binding lectin in febrile adults: no correlation with microbial infection and complement activation. J Clin Pathol (2003) 0.95

Mechanism of inhibition and induction of cytolytic activity in cytotoxic T lymphocytes by CD3 monoclonal antibodies. J Immunol (1987) 0.95

Evidence for a role of CD28RE as a response element for distinct mitogenic T cell activation signals. Eur J Immunol (1992) 0.95

The role of IL-13 in IgE synthesis by allergic asthma patients. Clin Exp Immunol (1998) 0.95

Pentoxifylline attenuates neutrophil activation in experimental endotoxemia in chimpanzees. J Immunol (1993) 0.95

Phagocytosis and degradation of DNA-anti-DNA complexes by human phagocytes. I. Assay conditions, quantitative aspects and differences between human blood monocytes and neutrophils. Eur J Immunol (1981) 0.94

Type 1- and type 2-like lesional skin-derived Mycobacterium leprae-responsive T cell clones are characterized by coexpression of IFN-gamma/TNF-alpha and IL-4/IL-5/IL-13, respectively. J Immunol (1998) 0.94

Cytokine production (IL-6 and TNF alpha) in whole blood cell cultures of patients with systemic lupus erythematosus. Scand J Rheumatol (1996) 0.91

Effects of smoking on the ex vivo cytokine production in periodontitis. J Periodontal Res (2008) 0.91

Two monoclonal anti-CD3 antibodies can induce different events in human T lymphocyte activation. Eur J Immunol (1987) 0.90

Regulation of IL-12 production by human monocytes and the influence of prostaglandin E2. Ann N Y Acad Sci (1996) 0.90

An improved incubation apparatus for Western blots used for the detection of antinuclear antibodies. J Immunol Methods (1986) 0.90

Functional studies with anti-CD3 heavy chain isotype switch-variant monoclonal antibodies. Accessory cell-independent induction of interleukin 2 responsiveness in T cells by epsilon-anti-CD3. J Immunol (1987) 0.89