Published in Clin Pharmacol Ther on October 01, 1965
Genetic control of the phenobarbital-induced shortening of plasma antipyrine half-lives in man. J Clin Invest (1969) 2.47
Genetic control of dicumarol levels in man. J Clin Invest (1968) 2.45
Genetic control of phenylbutazone metabolism in man. Br Med J (1970) 1.58
Enhancement of methyldopa metabolism with barbiturate. Br Med J (1971) 1.01
Induction of a deficiency of steroid delta 4-5 alpha-reductase activity in liver by a porphyrinogenic drug. J Clin Invest (1977) 0.79
Drugs and enzymes. Br Med J (1970) 0.75
Absence of changes in drug disposition and catecholamine sensitivity in the hyperthyroid dog. Br J Pharmacol (1980) 0.75
Phenytoin in post-operative cardiac arrhythmias. Br Heart J (1969) 0.75
The physiological disposition of phenylbutazone (butazolidin) in man and a method for its estimation in biological material. J Pharmacol Exp Ther (1953) 3.60
Substrate-induced synthesis and other properties of benzpyrene hydroxylase in rat liver. J Biol Chem (1957) 3.05
The fate of pentobarbital in man and dog and a method for its estimation in biological material. J Pharmacol Exp Ther (1953) 2.38
A potent new uricosuric agent, the sulfoxide metabolite of the phenylbutazone analogue, G-25671. J Pharmacol Exp Ther (1957) 2.20
Adaptive increases in drug-metabolizing enzymes induced by phenobarbital and other drugs. J Pharmacol Exp Ther (1960) 2.04
The metabolic fate of phenylbutazone (butazolidin) in man. J Pharmacol Exp Ther (1955) 1.76
The metabolism of methylated aminoazo dyes. V. Evidence for induction of enzyme synthesis in the rat by 3-methylcholanthrene. Cancer Res (1956) 1.64
Ascorbic acid synthesis in normal and drug-treated rats, studied with L-ascorbic-1-C14 acid. J Biol Chem (1954) 1.61
The synthesis of l-ascorbic acid by the albino rat. J Biol Chem (1950) 1.53
PUROMYCIN INHIBITION OF ENZYME INDUCTION BY 3-METHYLCHOLANTHRENE AND PHENOBARBITAL. J Biol Chem (1963) 1.44
Metabolism of drugs in subjects with Laennec's cirrhosis. Med Exp Int J Exp Med (1959) 1.38
Stimulatory effect of foreign compounds on ascorbic acid biosynthesis and on drug-metabolizing enzymes. Nature (1959) 1.26
Contrasting effects of thyroxin on zoxazolamine and hexobarbital metabolism. Biochem Pharmacol (1961) 1.22
Missing step in guinea pigs required for the biosynthesis of L-ascorbic acid. Science (1956) 1.22
Observations on the antirheumatic and physiologic effects of phenylbutazone (butazolidin) and some comparisons with cortisone. Am J Med (1954) 1.22
Stimulatory effect of barbital on urinary excretion of L-ascorbic acid and nonconjugated D-glucuronic acid. J Biol Chem (1957) 1.20
DRUG-INDUCED CHANGES IN STEROID METABOLISM. Ann N Y Acad Sci (1965) 1.19
Results of a clinical trial of G-28315, a sulfoxide analog of phenylbutazone, as a uricosuric agent in gouty subjects. Arthritis Rheum (1958) 1.18
Metabolism of ascorbic acid and related uronic acids, aldonic acids, and pentoses. Ann N Y Acad Sci (1961) 1.15
Metabolic interactions between L-ascorbic acid and drugs. Ann N Y Acad Sci (1961) 1.12
The metabolism of methylated aminoazo dyes. VI. Intracellular distribution and properties of the demethylase system. Cancer Res (1957) 1.11
Induction of microsomal enzyme synthesis by polycyclic aromatic hydrocarbons of different molecular sizes. J Biol Chem (1961) 1.10
The metabolism of 1-C14-L-ascorbic acid in guinea pigs. J Biol Chem (1951) 1.10
A study of the inverse relationship between pKa and rate of renal excretion of phenylbutazone analogs in man and dog. Am J Med (1960) 1.08
Biochemical pharmacological considerations of phenylbutazone and its analogues. Ann N Y Acad Sci (1960) 1.08
The biotransformation of ethyl biscoumacetate (tromexan) in man, rabbit and dog. J Pharmacol Exp Ther (1953) 1.08
The synthesis of L-ascorbic acid in the rat from D-glucuronolactone and L-gulonolactone. J Biol Chem (1956) 1.07
Phenylbutazone metabolites: antirheumatic, sodium-retaining and uricosuric effects in man. J Pharmacol Exp Ther (1958) 1.07
Metabolism of L-ascorbic acid-1-C14 in man. J Biol Chem (1958) 1.06
Studies on the glucuronic acid pathway of glucose metabolism. J Biol Chem (1959) 1.06
Missing step in man, monkey and guinea pig required for the biosynthesis of L-ascorbic acid. Nature (1957) 1.05
Zoxazolamine: physiological disposition, uricosuric properties. Am J Med (1958) 1.04
Observations on the drug-induced synthesis of D-glucuronic, L-gulonic and L-ascorbic acids in rats. J Pharmacol Exp Ther (1960) 1.03
SIMILARITIES BETWEEN OXIDATIVE DRUG-METABOLIZING ENZYMES AND STEROID HYDROXYLASES IN LIVER MICROSOMES. J Pharmacol Exp Ther (1964) 1.02
STIMULATORY EFFECT OF PHENOBARBITAL ON THE METABOLISM OF DIPHENYLHYDANTOIN. J Pharmacol Exp Ther (1963) 1.02
Induced synthesis of liver microsomal enzymes which metabolize foreign compounds. Science (1959) 1.01
Increased activity of androgen hydroxylases in liver microsomes of rats pretreated with phenobarbital and other drugs. J Biol Chem (1963) 1.01
The physiological disposition and fate of meperidine (demerol) in man and a method for its estimation in plasma. J Pharmacol Exp Ther (1955) 1.01
Intravenous anesthetics; new concepts. I. Experimental aspects. Curr Res Anesth Analg (1952) 0.98
Metabolism of L-gulonolactone in rats via pentose formation. Biochim Biophys Acta (1957) 0.97
Observations on G-25671, a phenylbutazone analogue (4-phenylthioethyl)-1,2-diphenyl 3,5-pyrazolidinedione). Proc Soc Exp Biol Med (1955) 0.97
Further observations on the metabolism of L-ascorbic acid in guinea pigs. J Biol Chem (1956) 0.97
The appearance of procaine in the spinal fluid during peridural block in man. J Pharmacol Exp Ther (1953) 0.96
Observations on vitamin C activity of D-ascorbic acid. Proc Soc Exp Biol Med (1959) 0.95
APPLICATION OF DRUG METABOLISM TO DRUG TOXICITY STUDIES. Ann N Y Acad Sci (1965) 0.95
Relationship between pKa and uricosuric activity in phenylbutazone analogues. Nature (1958) 0.95
INDUCED SYNTHESIS OF OXIDATIVE ENZYMES IN LIVER MICROSOMES BY POLYCYCLIC HYDROCARBONS AND DRUGS. Adv Enzyme Regul (1963) 0.94
Effect of a phenylbutazone analog (4-[phenylthioethyl]-1, 2-diphenyl 3, 5-pyrazolidinedione) on urate clearance and other discrete renal functions in gouty subjects; evaluation as uricosuric agent. J Clin Invest (1956) 0.93
BLOCKADE OF SOME METABOLIC EFFECTS OF CATECHOLAMINES BY N-ISOPROPYL METHOXAMINE (B.W. 61-43). J Pharmacol Exp Ther (1964) 0.92
The passage of thiopental into brain. J Pharmacol Exp Ther (1957) 0.91
Observations on the metabolic transformation and effects of phenylbutazone in subjects with hepatic disease. Am J Med Sci (1954) 0.91
IMPLICATIONS ON ENZYME INDUCTION FOR DRUG THERAPY. Am J Med (1964) 0.91
The passage of thiobarbiturates and their oxygen analogs into brain. J Pharmacol Exp Ther (1958) 0.90
Metabolism of sulfinpyrazone (Anturane) and other thio analogues of phenylbutazone in man. J Pharmacol Exp Ther (1961) 0.87
Conversion of myo-inositol to D-glucuronic acid and L-gulonic acid in the rat. Biochim Biophys Acta (1959) 0.87
Metabolism of C14-labeled ascorbic, dehydroascorbic and diketoglulonic acids in guinea pigs. Arch Biochem Biophys (1959) 0.87
The control of prothrombin activity with tromexan therapy. Am J Med (1953) 0.85
The physiological disposition of ethyl biscoumacetate (tromexan) in man and a method for its estimation in biological material. J Pharmacol Exp Ther (1952) 0.84
INHIBITION OF LIPID MOBILIZATION BY N-ISOPROPYL METHOXAMINE (B.W. 61-43). J Pharmacol Exp Ther (1964) 0.83
Metabolism of D-galactose to D-glucuronic acid, L-gulonic acid and L-ascorbic acid in normal and barbital-treated rats. Biochim Biophys Acta (1960) 0.82
Further observations on the biosynthesis of L-ascorbic acid from D-glucose in the rat. J Biol Chem (1956) 0.82
Metabolism of L-ascorbic acid in rat kidney. J Biol Chem (1958) 0.82
Studies on the incorporation of C14 administered as L-sorbose into L-ascorbic acid and D-glucose in rats. J Biol Chem (1955) 0.81
Studies of the mechanism of L-xylulose formation by kidney enzymes. J Biol Chem (1959) 0.80
Biosynthesis of L-ascorbic acid; basic defect in scurvy. Am J Med (1959) 0.80
The metabolic fate of zoxazolamine (flexin) in man. J Pharmacol Exp Ther (1960) 0.78
PHYSIOLOGICAL DISTRIBUTION AND METABOLIC INACTIVATION OF CHLORCYCLIZINE AND CYCLIZINE. J Pharmacol Exp Ther (1965) 0.77
The transmission of meperidine across the human placenta. Am J Obstet Gynecol (1952) 0.77
ENHANCED ANDROGEN HYDROXYLASE ACTIVITY IN LIVER MICROSOMES OF RATS AND DOGS TREATED WITH PHENYLBUTAZONE. J Pharmacol Exp Ther (1964) 0.77
Formation of L-lyxonic and L-xylonic acids from L-ascorbic acid in rat kidney. J Biol Chem (1960) 0.77
Physiological disposition and metabolic fate of chlorzoxazone (paraflex) in man. J Pharmacol Exp Ther (1960) 0.77
LOCAL BLOOD FLOW IN HUMAN LEG MUSCLE MEASURED BY A TRANSIENT RESPONSE THERMOELECTRIC METHOD. Biophys J (1965) 0.75
LOWERING EFFECT OF NEOSTIGMINE ON PLASMA FREE FATTY ACIDS. Nature (1964) 0.75
Metabolism of D-ascorbic acid-1-C14 in guinea pigs and rats. J Biol Chem (1958) 0.75
Biochemical pharmacological considerations of zoxazolamine and chlorzoxazone metabolism. Ann N Y Acad Sci (1960) 0.75
Stimulatory effect of chlorcyclizine on barbiturate metabolism. J Pharmacol Exp Ther (1961) 0.75
A p-nitro analogue of phenylbutazone possessing potent antirheumatic, sodium retaining and uricosuric properties. J Pharmacol Exp Ther (1959) 0.75
Water-soluble vitamins, Part I. (Ascorbic acid, nicotinic acid, vitamin B6, biotin, inositol). Annu Rev Biochem (1960) 0.75
Clinical application of studies of the physiologic disposition of thiopental. N Y State J Med (1956) 0.75
Physiologic disposition and uricosuric effect of a keto analog of oxyphenbutazone (G-29701). Arthritis Rheum (1960) 0.75
Role of ascorbic acid in the formation and maintenance of dental structures. Ann N Y Acad Sci (1961) 0.75
Observations on bound ascorbic acid in guinea pig liver. Proc Soc Exp Biol Med (1956) 0.75
THERAPEUTIC IMPLICATIONS OF DRUG METABOLISM. Semin Hematol (1964) 0.75
The induction of aminoazo dye N-demethylase in nonhepatic tissues by 3-methylcholanthrene. Biochem Pharmacol (1963) 0.75
Observations on effect of 3-methylcholanthrene in scorbutic guinea pigs. Proc Soc Exp Biol Med (1961) 0.75
Physiological disposition of certain N-alkyl thiobarbiturates. Anesthesiology (1955) 0.75