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1
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Use of high potency statins and rates of admission for acute kidney injury: multicenter, retrospective observational analysis of administrative databases.
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BMJ
|
2013
|
4.90
|
|
2
|
Long-term natural history of chronic obstructive pulmonary disease: severe exacerbations and mortality.
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Thorax
|
2012
|
4.06
|
|
3
|
Inhaled corticosteroids in COPD and the risk of serious pneumonia.
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Thorax
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2013
|
3.62
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|
4
|
Adult Asthma Consensus Guidelines update 2003.
|
Can Respir J
|
2004
|
3.61
|
|
5
|
Increased risk of childhood asthma from antibiotic use in early life.
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Chest
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2007
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3.11
|
|
6
|
Bronchodilator use and the risk of arrhythmia in COPD: part 1: Saskatchewan cohort study.
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Chest
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2012
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2.65
|
|
7
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Should combination therapy with inhaled corticosteroids and long-acting beta2-agonists be prescribed as initial maintenance treatment for asthma?
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CMAJ
|
2002
|
2.30
|
|
8
|
Fluoroquinolones and the risk of serious arrhythmia: a population-based study.
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Clin Infect Dis
|
2012
|
2.17
|
|
9
|
Cardiovascular morbidity and mortality in COPD.
|
Chest
|
2005
|
2.01
|
|
10
|
Underreporting exacerbation of chronic obstructive pulmonary disease in a longitudinal cohort.
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Am J Respir Crit Care Med
|
2007
|
1.85
|
|
11
|
Gender differences in survival following hospitalisation for COPD.
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Thorax
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2010
|
1.73
|
|
12
|
The use of inhaled corticosteroids and the risk of adrenal insufficiency.
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Eur Respir J
|
2012
|
1.67
|
|
13
|
Inhaled corticosteroids and the risks of diabetes onset and progression.
|
Am J Med
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2010
|
1.66
|
|
14
|
Canadian Pediatric Asthma Consensus guidelines, 2003 (updated to December 2004): introduction.
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CMAJ
|
2005
|
1.63
|
|
15
|
Airway remodeling in subjects with severe asthma with or without chronic persistent airflow obstruction.
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J Allergy Clin Immunol
|
2009
|
1.52
|
|
16
|
Differences in airway remodeling between subjects with severe and moderate asthma.
|
J Allergy Clin Immunol
|
2005
|
1.52
|
|
17
|
Airway inflammation assessed by invasive and noninvasive means in severe asthma: eosinophilic and noneosinophilic phenotypes.
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J Allergy Clin Immunol
|
2006
|
1.43
|
|
18
|
Bronchodilator use and the risk of arrhythmia in COPD: part 2: reassessment in the larger Quebec cohort.
|
Chest
|
2012
|
1.42
|
|
19
|
Increased expression of ADAM33 and ADAM8 with disease progression in asthma.
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J Allergy Clin Immunol
|
2007
|
1.40
|
|
20
|
Differences in airway cytokine profile in severe asthma compared to moderate asthma.
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Chest
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2007
|
1.36
|
|
21
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Implementing practice guidelines: a workshop on guidelines dissemination and implementation with a focus on asthma and COPD.
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Can Respir J
|
2006
|
1.32
|
|
22
|
Proton pump inhibitors and the risk of hospitalisation for community-acquired pneumonia: replicated cohort studies with meta-analysis.
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Gut
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2013
|
1.26
|
|
23
|
CNODES: the Canadian Network for Observational Drug Effect Studies.
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Open Med
|
2012
|
1.26
|
|
24
|
Geographic and gender variability in the prevalence of bronchial responsiveness in Canada.
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Chest
|
2004
|
1.26
|
|
25
|
Prevalence of obstructive sleep apnea-hypopnea in severe versus moderate asthma.
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J Allergy Clin Immunol
|
2009
|
1.18
|
|
26
|
Childhood predictors of smoking in adolescence: a follow-up study of Montreal schoolchildren.
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CMAJ
|
2005
|
1.16
|
|
27
|
Bias in observational study of the effectiveness of nasal corticosteroids in asthma.
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J Allergy Clin Immunol
|
2005
|
1.14
|
|
28
|
Risks of pneumonia in patients with asthma taking inhaled corticosteroids.
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Am J Respir Crit Care Med
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2010
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1.12
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29
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Implementation of a targeted screening program to detect airflow obstruction suggestive of chronic obstructive pulmonary disease within a presurgical screening clinic.
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Can Respir J
|
2015
|
1.09
|
|
30
|
Inhaled and nasal corticosteroid use and the risk of fracture.
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Am J Respir Crit Care Med
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2003
|
1.07
|
|
31
|
T Cells localize with proliferating smooth muscle alpha-actin+ cell compartments in asthma.
|
Am J Respir Crit Care Med
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2010
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1.04
|
|
32
|
The Asthma Quiz for Kidz: a validated tool to appreciate the level of asthma control in children.
|
Can Respir J
|
2004
|
0.96
|
|
33
|
The determinants of prevalence of health complaints among young competitive swimmers.
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Int Arch Occup Environ Health
|
2006
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0.96
|
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34
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Adjustable maintenance dosing with budesonide/formoterol reduces asthma exacerbations compared with traditional fixed dosing: a five-month multicentre Canadian study.
|
Can Respir J
|
2003
|
0.95
|
|
35
|
Inhaled corticosteroids and risk of tuberculosis in patients with respiratory diseases.
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Am J Respir Crit Care Med
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2010
|
0.94
|
|
36
|
Oral corticosteroid use and the risk of acute myocardial infarction in chronic obstructive pulmonary disease.
|
Can Respir J
|
2006
|
0.93
|
|
37
|
Inhaled corticosteroid use in asthma and the prevention of myocardial infarction.
|
Am J Med
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2003
|
0.91
|
|
38
|
The impact of over-the-counter simvastatin on the number of statin prescriptions in the United Kingdom: a view from the General Practice Research Database.
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Pharmacoepidemiol Drug Saf
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2007
|
0.90
|
|
39
|
TNF-alpha antagonists and the prevention of hospitalisation for chronic obstructive pulmonary disease.
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Pulm Pharmacol Ther
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2007
|
0.90
|
|
40
|
Symposium on obesity and asthma - November 2, 2006.
|
Can Respir J
|
2007
|
0.89
|
|
41
|
Leflunomide use and the risk of interstitial lung disease in rheumatoid arthritis.
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Arthritis Rheum
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2006
|
0.87
|
|
42
|
Effect of a web-based chronic disease management system on asthma control and health-related quality of life: study protocol for a randomized controlled trial.
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Trials
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2011
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0.86
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43
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Airflow obstruction in young adults in Canada.
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Can Respir J
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2007
|
0.86
|
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44
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Discontinuation of Inhaled Corticosteroids in COPD and the Risk Reduction of Pneumonia.
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Chest
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2015
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0.85
|
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45
|
Women and asthma: lessons from a gender analysis of the asthma in Canada survey.
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J Asthma
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2006
|
0.85
|
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46
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Patterns and determinants of compliance with inhaled steroids in adults with asthma.
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Can Respir J
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2005
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0.85
|
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47
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Statins and the risk of interstitial lung disease: a cohort study.
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Thorax
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2013
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0.84
|
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48
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Evaluating asthma control: a comparison of measures using an item response theory approach.
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J Asthma
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2007
|
0.83
|
|
49
|
Psychologic distress and maladaptive coping styles in patients with severe vs moderate asthma.
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Chest
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2010
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0.83
|
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50
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Development and validation of a predictive algorithm to identify adult asthmatics from medical services and pharmacy claims databases.
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Health Serv Res
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2011
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0.83
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51
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Rates and patterns of chronic obstructive pulmonary disease exacerbations.
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Can Respir J
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2004
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0.83
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52
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Increased glucocorticoid receptor-beta expression, but not decreased histone deacetylase 2, in severe asthma.
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J Allergy Clin Immunol
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2006
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0.83
|
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53
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Altitude-related hypoxia: risk assessment and management for passengers on commerical aircraft.
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Aviat Space Environ Med
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2003
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0.82
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54
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Asthma and allergic rhinitis in Quebec children.
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Can Respir J
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2004
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0.81
|
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55
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Risk of glaucoma in elderly patients treated with inhaled corticosteroids for chronic airflow obstruction.
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Pulm Pharmacol Ther
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2009
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0.81
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56
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Facilitators and solutions for practicing optimal guided asthma self-management: the physician perspective.
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Can Respir J
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2013
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0.81
|
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57
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Correlates of quality of life in patients with asthma.
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Ann Allergy Asthma Immunol
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2005
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0.81
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58
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Pesticide exposure and asthma.
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Am J Respir Crit Care Med
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2002
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0.80
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59
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Validation of The 30 Second Asthma Test as a measure of asthma control.
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Can Respir J
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2007
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0.80
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60
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Newer disease-modifying antirheumatic drugs and the risk of serious hepatic adverse events in patients with rheumatoid arthritis.
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Am J Med
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2004
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0.78
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61
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Safety and efficacy of HFA-134a beclomethasone dipropionate extra-fine aerosol over six months.
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Can Respir J
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2004
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0.78
|
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62
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Effectiveness of combination therapies in asthma: an observational study.
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Pulm Pharmacol Ther
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2008
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0.78
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63
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Integrated interdisciplinary care for patients with chronic obstructive pulmonary disease reduces emergency department visits, admissions and costs: a quality assurance study.
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Can Respir J
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2013
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0.77
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64
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Evaluation of the use of an integrated drug information system by primary care physicians for vulnerable population.
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Int J Med Inform
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2007
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0.77
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65
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A population-based evaluation of a regional asthma education centre.
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Can Respir J
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2004
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0.76
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66
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β-blockers for COPD inpatients.
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Thorax
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2012
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0.76
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67
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Association between physician competence at licensure and the quality of asthma management among patients with out-of-control asthma.
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Arch Intern Med
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2011
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0.76
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68
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Predictors of perceived asthma control among patients managed in primary care clinics.
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Qual Life Res
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2014
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0.76
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69
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Inhaled corticosteroids and fracture risk in COPD.
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Am J Respir Crit Care Med
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2004
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0.75
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70
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Differences between asthmatics and nonasthmatics hospitalised with influenza A infection.
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Eur Respir J
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2013
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0.75
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71
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Antibiotic therapy in patients hospitalized with acute chronic obstructive pulmonary disease.
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JAMA
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2010
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0.75
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72
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Asthma worsenings: approaches to prevention and management from the Asthma Worsenings Working Group.
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Can Respir J
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2009
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0.75
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73
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The effects of a multisite aerobic exercise intervention on asthma morbidity in sedentary adults with asthma: the Ex-asthma study randomised controlled trial protocol.
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BMJ Open
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2013
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0.75
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74
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Reply to Trezza et Al.
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Clin Infect Dis
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2013
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0.75
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75
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Response.
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Chest
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2013
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0.75
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76
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Taking airway disease seriously.
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Thorax
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2014
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0.75
|
|
77
|
Environmental measures and asthma.
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Chest
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2002
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0.75
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|
78
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How much did biases in the study of chronic obstructive pulmonary disease medications and mortality affect the outcome?
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Ann Intern Med
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2009
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0.75
|
|
79
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Mega trials in COPD--clinical data analysis and design issues.
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Pneumonol Alergol Pol
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2011
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0.75
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|
80
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Teaching time for metered-dose inhalers in the emergency setting.
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Chest
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2002
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0.75
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|
81
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Total and specific immunoglobulin E and their relationship to respiratory symptoms in Quebéc children and adolescents.
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Can Respir J
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2005
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0.75
|
|
82
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Phenotypic heterogeneity of potentially curable non-small-cell lung cancer: cohort study with cluster analysis.
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J Thorac Oncol
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2015
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0.75
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